每日简报

DoubleML：R 中双重机器学习的面向对象实现AI 解读

The R package DoubleML implements the double/debiased machine learning framework of Chernozhukov et al. (2018). It provides functionalities to estimate parameters in causal models based on machine learning methods. The double machine learning framework consist of three key ingredients: Neyman orthogonality, high-quality machine learning estimation and sample splitting. Estimation of nuisance components can be performed by various state-of-the-art machine learning methods…

未观测混杂下利用负向对照的因果推断：极小极大学习方法AI 解读

We study the estimation of causal parameters when not all confounders are observed and instead negative controls are available. Recent work has shown how these can enable identification and efficient estimation via two so-called bridge functions. In this paper, we tackle the primary challenge to causal inference using negative controls: the identification and estimation of these bridge functions. Previous work has relied on completeness conditions on these functions to…

重新审视 g-null 悖论AI 解读

The parametric g-formula is an approach to estimating causal effects of sustained treatment strategies from observational data. An often cited limitation of the parametric g-formula is the g-null paradox: a phenomenon in which model misspecification in the parametric g-formula is guaranteed under the conditions that motivate its use (i.e., when identifiability conditions hold and measured time-varying confounders are affected by past treatment). Many users of the parametric…

非嵌套设计中将试验证据推广至目标人群：艾滋病临床试验应用AI 解读

Comparative effectiveness evidence from randomized trials may not be directly generalizable to a target population of substantive interest when, as in most cases, trial participants are not randomly sampled from the target population. Motivated by the need to generalize evidence from two trials conducted in the AIDS Clinical Trials Group (ACTG), we consider weighting, regression and doubly robust estimators to estimate the causal effects of HIV interventions in a specified…

异质数据来源下个性化处理效应的树模型平均方法AI 解读

Accurately estimating personalized treatment effects within a study site (e.g., a hospital) has been challenging due to limited sample size. Furthermore, privacy considerations and lack of resources prevent a site from leveraging subject-level data from other sites. We propose a tree-based model averaging approach to improve the estimation accuracy of conditional average treatment effects (CATE) at a target site by leveraging models derived from other potentially…

成本不确定时的处理分配AI 解读

We consider the problem of learning how to optimally allocate treatments whose cost is uncertain and can vary with pre-treatment covariates. This setting may arise in medicine if we need to prioritize access to a scarce resource that different patients would use for different amounts of time, or in marketing if we want to target discounts whose cost to the company depends on how much the discounts are used. Here, we show that the optimal treatment allocation rule under…

NCoRE：组合治疗的神经网络反事实表示学习AI 解读

Estimating an individual's potential response to interventions from observational data is of high practical relevance for many domains, such as healthcare, public policy or economics. In this setting, it is often the case that combinations of interventions may be applied simultaneously, for example, multiple prescriptions in healthcare or different fiscal and monetary measures in economics. However, existing methods for counterfactual inference are limited to settings in…

是个体构成还是所在环境？分解跨站点处理效应差异AI 解读

Multisite trials, in which treatment is randomized separately in multiple sites, offer a unique opportunity to disentangle treatment effect variation due to "compositional" differences in the distributions of unit-level features from variation due to "contextual" differences in site-level features. In particular, if we can re-weight (or "transport") each site to have a common distribution of unit-level covariates, the remaining effect variation captures contextual…

工具变量面板设计的更稳健估计：以中国进口对美国就业的影响为例AI 解读

We show that first-difference two-stages-least-squares regressions identify non-convex combinations of location-and-period-specific treatment effects. Thus, those regressions could be biased if effects are heterogeneous. We propose an alternative instrumental-variable correlated-random-coefficient (IV-CRC) estimator, that is more robust to heterogeneous effects. We revisit Autor et al. (2013), who use a first-difference two-stages-least-squares regression to estimate the…

你喜欢有向无环图吗？结构学习与因果发现综述AI 解读

Causal reasoning is a crucial part of science and human intelligence. In order to discover causal relationships from data, we need structure discovery methods. We provide a review of background theory and a survey of methods for structure discovery. We primarily focus on modern, continuous optimization methods, and provide reference to further resources such as benchmark datasets and software packages. Finally, we discuss the assumptive leap required to take us from…

暴露映射误设下的因果推断：分离效应定义与结构假设AI 解读

Exposure mappings facilitate investigations of complex causal effects when units interact in experiments. Current methods require experimenters to use the same exposure mappings both to define the effect of interest and to impose assumptions on the interference structure. However, the two roles rarely coincide in practice, and experimenters are forced to make the often questionable assumption that their exposures are correctly specified. This paper argues that the two roles…

带约束的经验福利最大化AI 解读

Empirical Welfare Maximization (EWM) is a framework that can be used to select welfare program eligibility policies based on data. This paper extends EWM by allowing for uncertainty in estimating the budget needed to implement the selected policy, in addition to its welfare. Due to the additional estimation error, I show there exist no rules that achieve the highest welfare possible while satisfying a budget constraint uniformly over a wide range of DGPs. This differs from…

利用控制变量法进行多来源因果推断AI 解读

While many areas of machine learning have benefited from the increasing availability of large and varied datasets, the benefit to causal inference has been limited given the strong assumptions needed to ensure identifiability of causal effects; these are often not satisfied in real-world datasets. For example, many large observational datasets (e.g., case-control studies in epidemiology, click-through data in recommender systems) suffer from selection bias on the outcome,…

时间序列干预因果效应的估计：C-ARIMA 方法AI 解读

The Rubin Causal Model (RCM) is a framework that allows to define the causal effect of an intervention as a contrast of potential outcomes. In recent years, several methods have been developed under the RCM to estimate causal effects in time series settings. None of these makes use of ARIMA models, which are instead very common in the econometrics literature. In this paper, we propose a novel approach, C-ARIMA, to define and estimate the causal effect of an intervention in a…

中位数最优处理规则AI 解读

Optimal treatment regimes are personalized policies for making a treatment decision based on subject characteristics, with the policy chosen to maximize some value. It is common to aim to maximize the mean outcome in the population, via a regime assigning treatment only to those whose mean outcome is higher under treatment versus control. However, the mean can be an unstable measure of centrality, resulting in imprecise statistical procedures, as well as unrobust decisions…

时间一致的中心极限定理与渐近置信序列AI 解读

Confidence intervals based on the central limit theorem (CLT) are a cornerstone of classical statistics. Despite being only asymptotically valid, they are ubiquitous because they permit statistical inference under weak assumptions and can often be applied to problems even when nonasymptotic inference is impossible. This paper introduces time-uniform analogues of such asymptotic confidence intervals, adding to the literature on confidence sequences (CS) -- sequences of…

工具变量设计中依从者的特征刻画AI 解读

Instrumental variable (IV) analyses are becoming common in health services research and epidemiology. IV analyses can be used both to analyze randomized trials with noncompliance and as a form of natural experiment. In these analyses, investigators often adopt a monotonicity assumption, which implies that the relevant effect only applies to a subset of the study population known as compliers. Since the estimated effect is not the average treatment effect of the study…

用于电力消费预测的面板半参数分位数回归神经网络AI 解读

China has made great achievements in electric power industry during the long-term deepening of reform and opening up. However, the complex regional economic, social and natural conditions, electricity resources are not evenly distributed, which accounts for the electricity deficiency in some regions of China. It is desirable to develop a robust electricity forecasting model. Motivated by which, we propose a Panel Semiparametric Quantile Regression Neural Network (PSQRNN) by…

利用历史数据进行高维回归调整：复合协变量方法AI 解读

The amount of data collected from patients involved in clinical trials is continuously growing. All patient characteristics are potential covariates that could be used to improve clinical trial analysis and power. However, the restricted number of patients in phases I and II studies limits the possible number of covariates included in the analyses. In this paper, we investigate the cost/benefit ratio of including covariates in the analysis of clinical trials. Within this…

新处理长期效应的估计AI 解读

Policy makers typically face the problem of wanting to estimate the long-term effects of novel treatments, while only having historical data of older treatment options. We assume access to a long-term dataset where only past treatments were administered and a short-term dataset where novel treatments have been administered. We propose a surrogate based approach where we assume that the long-term effect is channeled through a multitude of available short-term proxies. Our…

利用贝叶斯加性回归树将外部数据纳入临床试验分析AI 解读

Most clinical trials involve the comparison of a new treatment to a control arm (e.g., the standard of care) and the estimation of a treatment effect. External data, including historical clinical trial data and real-world observational data, are commonly available for the control arm. Borrowing information from external data holds the promise of improving the estimation of relevant parameters and increasing the power of detecting a treatment effect if it exists. In this…

非正态误差大面板的截面独立性拉格朗日乘子检验扩展AI 解读

This paper reexamines the seminal Lagrange multiplier test for cross-section independence in a large panel model where both the number of cross-sectional units n and the number of time series observations T can be large. The first contribution of the paper is an enlargement of the test with two extensions: firstly the new asymptotic normality is derived in a simultaneous limiting scheme where the two dimensions (n, T) tend to infinity with comparable magnitudes; second, the…

量化因果推断所需的充分随机性AI 解读

Spurious association arises from covariance between propensity for the treatment and individual risk for the outcome. For sensitivity analysis with stochastic counterfactuals we introduce a methodology to characterize uncertainty in causal inference from natural experiments and quasi-experiments. Our sensitivity parameters are standardized measures of variation in propensity and individual risk, and one minus their geometric mean is an intuitive measure of randomness in the…

因果效应估计的贝叶斯模型平均及高斯尺度混合近似AI 解读

In the estimation of the causal effect under linear Structural Causal Models (SCMs), it is common practice to first identify the causal structure, estimate the probability distributions, and then calculate the causal effect. However, if the goal is to estimate the causal effect, it is not necessary to fix a single causal structure or probability distributions. In this paper, we first show from a Bayesian perspective that it is Bayes optimal to weight (average) the causal…