每日简报

小噪声下维度发散的网络随机微分方程推断AI 解读

We consider inference for network stochastic differential equations in a small-noise, high-dimensional regime, where the diffusion coefficient vanishes with $\ep\to0$ while the network size and parameter dimension may diverge. We develop a minimum-distance estimation framework based on a deterministic measurement model that may omit nuisance terms in the drift, and derive a non-asymptotic error bound decomposing the estimation error into stochastic fluctuation, nuisance…

协变量密度有界条件下期望条件协方差的极小极大估计AI 解读

In many scientific studies, evaluating the association between two responses requires adjusting for shared covariates. The expected conditional covariance measures this adjusted association and is used in conditional independence testing and treatment effect estimation. Researchers often estimate it using fitted conditional means, but removing the bias caused by the estimation errors of these conditional means remains a difficult task. This difficulty can increase when the…

暴露与结局关系非线性时，两样本孟德尔随机化估计什么？AI 解读

Two-sample Mendelian randomization with summary statistics has become a popular MR design in Epidemiology. Its ratio estimate has an average causal effect interpretation only under strong untestable assumptions including linearity. We derive what the per-variant ratio, and the pooled and robust estimators built from it, estimate when a continuous exposure has a nonlinear effect, under two conditions on how genetic variation and unmeasured factors shape exposure: no…

利用辅助事件信息进行删失结局的因果推断AI 解读

Clinical trials with survival endpoints lose information when participants are censored before death is observed. We develop target-preserving estimators that use posttreatment disease history, such as recurrence or progression, to recover information lost to censoring for marginal survival and restricted mean survival effects. The difficulty is that the intermediate event is downstream of treatment: naive adjustment can change the causal estimand, and the useful information…

删失随机试验中限制平均生存时间处理获益排序的直接学习AI 解读

In precision medicine, treatment decisions often depend more on identifying which patients are most likely to benefit from treatment than on accurately estimating benefit for every patient. However, existing methods estimate patient-specific treatment effects and derive patient rankings as a secondary step. We propose a direct ranking approach for conditional RMST treatment benefit in randomized trials with right-censored outcomes. We first construct a censoring-adjusted…

跨度之外共同冲击下的合成控制：诊断、暴露平衡与修正AI 解读

Synthetic control relies on pre-treatment fit to balance the unobserved factors that drive untreated outcomes. The argument fails when an observed common shock, such as a commodity price, moves with the latent factors before treatment and departs from them afterwards and pre-treatment fit then says almost nothing about the synthetic unit's exposure to the shock. I derive a period-specific bound that links the post-treatment bias of any weighting estimator to pre-treatment…

二元结果混合对照试验的稳健估计与推断：非小细胞肺癌案例AI 解读

Hybrid controlled trials (HCTs), which augment randomized controlled trials (RCTs) with external controls (ECs), are increasingly receiving attention as a way to address limited power, slow accrual, and ethical concerns in clinical research. However, borrowing from ECs raises critical statistical challenges in estimation and inference, especially for binary outcomes where hidden bias is harder to detect and estimands such as risk difference, risk ratio, and odds ratio are of…

稀疏依赖下二元配置概率的对抗估计AI 解读

We consider the problem of estimating binary configuration probabilities, which is common in operations management applications, including product bundling, advertising, etc. Existing approaches typically model each assortment as a category and apply multinomial models to estimate the choice probabilities; while computationally convenient, these methods do not exploit independence structures in the joint distribution and may therefore be statistically inefficient when the…