Transporting summary measures of relative effects from randomised trials to the treated patient population: an application to breast cancer endocrine therapy
将随机试验的相对效应汇总量迁移至已治疗患者:乳腺癌内分泌治疗应用
Randomised trials often report relative treatment effects, such as risk ratios and hazard ratios, for trial populations. Clinical decision-making, however, often benefits from estimates of absolute treatment effects in the population eligible for treatment. Trial participants may not represent this target population well, and restrictions on access to individual participant trial data can further complicate absolute effect estimation. Routine care data are often…