Scalable Bayesian structure learning of directed acyclic graphs via Laplace approximation, with an application to breast cancer gene expression networks
通过拉普拉斯近似实现可扩展的贝叶斯有向无环图结构学习及乳腺癌应用
Structure learning of directed acyclic graphs (DAGs) from observational data is a foundational task in causal discovery and is widely used to infer regulatory networks from medical and genomic measurements. The Bayesian formulation quantifies model uncertainty and admits prior biological knowledge, but its practical use has been hampered by the super-exponential growth of the DAG space and by the intractability of the node-marginal likelihood under flexible, non-conjugate…