每日简报

数据稀疏临床队列生存风险分层的结构化迁移学习AI 解读

Background: Survival prediction models are often less reliable in clinical groups with limited sample sizes or few outcome events. Target-only models may be unstable, whereas models from larger cohorts may transfer poorly when risk-factor effects differ across populations. We evaluated whether structured transfer learning can improve survival risk stratification in data-sparse cohorts while allowing cohort-specific adaptation. Methods: We developed the COhort-shared…

高维平滑支持向量机的统计推断：从离线到在线数据AI 解读

High-dimensional classification problems often rely on the Lasso-penalized linear Support Vector Machines (SVMs). However, the double non-smoothness induced by the hinge loss and Lasso penalty in this model makes statistical inference challenging and impedes computational efficiency. In this paper, we propose a unified inference framework in both offline and online settings. In the offline case, by applying a convolution smoothing technique to the hinge loss, we construct a…

时间序列长期方差估计中的尾部后着色AI 解读

Prewhitening is a common approach to deal with strong autocorrelation. In this article, we propose a new approach called tail postcoloring, motivated by it. It uses parametric models to project, or color back, the neglected tail autocovariances in nonparametric estimators onto the final estimator. This approach bridges the non-parametric variance estimator and the parametric coloring model through a scaling factor. It automatically switches between these two arms using a…

利用异质性实现可识别性：多个有向无环图的贝叶斯排序学习AI 解读

We propose a joint order-based scoring framework for causal structure learning of directed acyclic graph (DAG) models under heterogeneous data settings. We show that leveraging heterogeneity improves the accuracy of causal ordering estimation. In the most favorable case, the causal ordering is identifiable up to two permutations. Building on this framework, we propose an order-based Bayesian method for Gaussian DAG models and establish its theoretical properties in the…

重新审视并校准用于因果推断的加权生存分析AI 解读

Causal inference with time-to-event outcomes is fundamental in various scientific studies. In a static setup with fitted propensity scores, weighted Kaplan-Meier estimation for survival probabilities and weighted Breslow-Peto estimation for hazard ratios have been widely used, but their statistical properties have been overlooked or studied only to a limited extent. We re-examine the weighted Kaplan-Meier method by formally linking it with the general framework of augmented…

具有图 Ornstein–Uhlenbeck 动态的边索引网络时间序列AI 解读

We introduce a class of Lévy-driven graph Ornstein-Uhlenbeck (grOU) models for edge-indexed network time series. The proposed framework extends generalized network autoregressive (GNAR) processes for edge-indexed network time series to continuous time and adapts graph Ornstein-Uhlenbeck dynamics, originally developed for node-indexed processes, to the edge-indexed setting. The model accommodates general Lévy noise and therefore captures both Brownian and jump behavior. We…

准贝叶斯局部投影工具变量法：可再生能源与电价应用AI 解读

This paper introduces a quasi-Bayesian approach for local projection instrumental-variables (LP-IV) estimation. It builds a moment-based quasi-posterior using the generalized method of moments (GMM) objective and applies a roughness-penalty prior to smooth impulse responses over different horizons. The approach maintains the key first-order features of traditional LP-IV methods, while enhancing stability in finite samples and allowing for joint inference through simultaneous…

无界支撑上的最近邻匹配与协变量漂移迁移AI 解读

Expectations of multivariate functions with missing labels occur in various fields such as transfer learning and average treatment effects. Although non-parametric estimators based on nearest-neighbour matching are frequently used in this context, the existing literature assumes that the covariates live in some well-shaped compact subset of $\R^d$, with densities that are bounded away from zero. In this paper, we show that the usual rates of convergence can be achieved with…

基于观察数据的政策学习：HIV/HCV 共感染患者的丙肝治疗AI 解读

Decision-makers frequently must choose a single action from a finite set of alternatives -- for example, physicians selecting a treatment, investors choosing a portfolio risk level, or judges determining sentences. To improve outcomes, policymakers often issue policy rules or guidelines to inform such choices. In this paper, I show how to generally derive policy rules from observational data in a multi-action framework under relatively weak assumptions about the underlying…

Tweedie 公式与得分驱动更新AI 解读

Score-driven models update time-varying parameters using conditional likelihood scores. This paper develops a Bayesian interpretation of such updates through Tweedie's formula, which connects posterior mean corrections with marginal scores. In Gaussian signal extraction, this gives an exact posterior-correction identity. For natural exponential families, related identities characterize posterior means in natural- and expectation-parameter spaces. Building on these…

Incentives in experimental design are often misaligned: experimenters design and finance experiments to seek regulatory approval, while regulators seek to maximize social welfare. This incentive misalignment is especially relevant for Bayesian and adaptive trial designs, which have gained substantial popularity in recent years and have been actively encouraged by the US Food and Drug Administration. We propose a framework to resolve this conflict, wherein regulators set a…

NMF-FFB：具有前馈-反馈结构的非负矩阵分解AI 解读

Non-negative matrix factorization (NMF) approximates a non-negative endogenous data matrix as $Y_1 \approx XB$, with non-negative latent components $X$ and coefficients $B$. Standard covariate-aware NMF is feedforward: $B$ depends only on exogenous variables $Y_2$, with no latent feedback among endogenous variables. We propose NMF-FFB (NMF with feedforward-feedback structure), an exploratory data-fitting framework that embeds the simultaneous equation $B = Θ_1 Y_1 + Θ_2 Y_2$…

稀疏Probit回归的均值场变分贝叶斯方法AI 解读

We consider Bayesian variable selection for binary outcomes under a probit link with a spike-and-slab prior on the regression coefficients. Motivated by the computational challenges encountered by Markov chain Monte Carlo (MCMC) samplers in high-dimensional regimes, we develop a mean-field variational Bayes approximation in which all variational factors admit closed-form updates, and the evidence lower bound is available in closed form. This, in turn, allows the development…

收入分布与COPD患病率的空间异质成分回归：地理加权惩罚方法AI 解读

Income inequality is a major contributor to health disparities, yet its effects often vary by geography and are commonly represented as compositional distributions (e.g., proportions of households across income brackets). Existing spatial regression methods struggle in this setting: they typically assume smooth spatial variation, cannot accommodate abrupt spatial heterogeneity, and lack principled treatment of compositional covariates. We propose a geographically weighted…

具有干扰、时间序列数据与随机网络的二部因果推断AI 解读

In bipartite causal inference with interference, interventional units might receive treatment or control, and they might affect the outcome of outcome units through their connections on a bipartite network. We study bipartite causal inference with interference based on observational data across time and a changing bipartite network. Under an exposure mapping framework, we define the immediate and carryover causal effects for each outcome unit, representing contrasts of…

高斯序列因果条件有向信息率的非渐近误差界AI 解读

Directed information and its causally conditioned variations are often used to measure causal influences between random processes. In practice, these quantities must be measured from data. Non-asymptotic error bounds for these estimates are known for sequences over finite alphabets, but less is known for real-valued data. This paper examines the case in which the data are sequences of Gaussian vectors. We provide an explicit formula for causally conditioned directed…

观察研究中效应修饰的子群感知评分方法AI 解读

Effect modification means the size of a treatment effect varies with an observed covariate. Generally speaking, a larger treatment effect with more stable error terms is less sensitive to bias. Thus, we might be able to conclude that a study is less sensitive to unmeasured bias by using these subgroups experiencing larger treatment effects. Lee et al. (2018) proposed the submax method that leverages the joint distribution of test statistics from subgroups to draw a firmer…

再随机化与分层再随机化下灵活协变量调整的渐近推断AI 解读

Rerandomization is an effective treatment allocation procedure to control for baseline covariate imbalance. For estimating the average treatment effect, rerandomization has been previously shown to improve the precision of the unadjusted and the linearly-adjusted estimators over simple randomization without compromising consistency. However, it remains unclear whether such results apply more generally to the class of M-estimators, including the g-computation formula with…

在目标试验中嵌入目标研究：评估干预对群体差距的影响AI 解读

We present a novel framework (TS+TT) to nest a Target Study (TS) within a Target Trial (TT) for evaluating the effects of interventions on disparities. The TS component grounds the measurement of disparity in ethical assumptions, based on the concept of allowability, and anchors it to an explicit population within calendar time. It specifies an enrollment plan of stratified sampling of eligible persons to yield a sample where social groups are distributionally similar on…