每日简报

基于中介相关引导贝叶斯变量选择的高维广义线性模型中介分析AI 解读

High-dimensional mediation analysis aims to identify mediating pathways and to estimate indirect effects linking an exposure to an outcome. In this paper, we propose a Bayesian framework to address key challenges in these analyses, including high dimensionality, complex dependence among omics mediators, and non-continuous outcomes. Furthermore, commonly used approaches assume independent mediators or ignore correlations in the selection stage, which can reduce power when…

线性反问题中的批量贝叶斯最优实验设计AI 解读

Experimental design is central to science and engineering. A ubiquitous challenge is how to maximize the value of information obtained from expensive or constrained experimental settings. Bayesian optimal experimental design (OED) provides a principled framework for addressing such questions. In this paper, we study experimental design problems such as the optimization of sensor locations over a continuous domain in the context of linear Bayesian inverse problems. We focus…

利用聚类刀切法改进 CSDID 推断AI 解读

Obtaining reliable inferences with traditional difference-in-differences (DiD) methods can be difficult. Problems can arise when both outcomes and errors are serially correlated, when there are few clusters or few treated clusters, when cluster sizes vary greatly, and in various other cases. In recent years, recognition of the ``staggered adoption'' problem has shifted the focus away from inference towards consistent estimation of treatment effects. One of the most popular…

误设下溢出效应的分解：伪真估计目标与局部—全局扩展AI 解读

To measure spillovers, researchers often summarize who else was treated with a simple measure, such as the share of treated neighbors. We study what the researcher estimates when that summary is misspecified. We show that the researcher estimates the best approximation to the true policy effect among all functionals of the chosen summary, and that the usual direct and spillover estimates are exactly the components of this approximation. Under a monotonicity restriction, the…

近似留一交叉验证与平均场推断的同步分析AI 解读

Approximate Leave-One-Out Cross-Validation (ALO-CV) is a method that has been proposed to estimate the generalization error of a regularized estimator in the high-dimensional regime where dimension and sample size are of the same order, the so-called ``proportional regime''. A new analysis is developed to derive the consistency of ALO-CV for non-differentiable regularizers under Gaussian covariates and strong convexity. Using a conditioning argument, the difference between…

单指标模型中正则化 M 估计量的可观测调整AI 解读

We consider observations $(X,y)$ from single index models with unknown link function, Gaussian covariates and a regularized M-estimator $\hatβ$ constructed from convex loss function and regularizer. In the regime where sample size $n$ and dimension $p$ are both increasing such that $p/n$ has a finite limit, the behavior of the empirical distribution of $\hatβ$ and the predicted values $X\hatβ$ has been previously characterized in a number of models: The empirical…

从适度相互作用随机粒子系统严格推导退化抛物-椭圆Keller-Segel系统：第二部分 混沌传播AI 解读

This work is a series of two articles. The main goal is to rigorously derive the degenerate parabolic-elliptic Keller-Segel system in the sub-critical regime from a moderately interacting stochastic particle system. In the first article [7], we establish the classical solution theory of the degenerate parabolic-elliptic Keller-Segel system and its non-local version. In the second article, which is the current one, we derive a propagation of chaos result, where the classical…

超越平均处理效应：A/B 测试的多准则设计AI 解读

In the era of large-scale AI deployment and high-stakes clinical trials, adaptive experimentation faces a ``trilemma'' of conflicting objectives: minimizing cumulative regret (welfare loss during the experiment), maximizing the estimation accuracy of heterogeneous treatment effects (CATE), and ensuring differential privacy (DP) for participants. Existing literature typically optimizes these metrics in isolation or under restrictive parametric assumptions. In this work, we…

正值性违反下连续处理的可行剂量反应曲线AI 解读

Positivity violations can complicate estimation and interpretation of causal dose-response curves (CDRCs) for continuous interventions. Weighting-based methods are designed to handle limited overlap, but the resulting weighted targets can be hard to interpret scientifically. Modified treatment policies can be less sensitive to support limitations, yet they typically target policy-defined effects that may not align with the original dose-response question. We develop an…

半离散最优输运中的分位数优化AI 解读

Optimal transport is the problem of designing a joint distribution for two random variables with fixed marginals. In virtually the entire literature on this topic, the objective is to minimize expected cost. This paper is the first to study a variant in which the goal is to minimize a quantile of the cost, rather than the mean. For the semidiscrete setting, where one distribution is continuous and the other is discrete, we derive a complete characterization of the optimal…

含随机效应的混合分数 Black–Scholes 模型：离散观测下的混合估计AI 解读

We propose a hybrid estimation procedure to estimate global fixed parameters and subject-specific random effects in a mixed fractional Black-Scholes model based on discrete-time observations. Specifically, we consider $N$ independent stochastic processes, each driven by a linear combination of standard Brownian motion and an independent fractional Brownian motion, and governed by a drift term that depends on an unobserved random effect with unknown distribution. Based on $n$…

通过条件最优输运实现因果部分识别AI 解读

We study the estimation of causal estimand involving the joint distribution of treatment and control outcomes for a single unit. In typical causal inference settings, it is impossible to observe both outcomes simultaneously, which places our estimation within the domain of partial identification (PI). Pre-treatment covariates can substantially reduce estimation uncertainty by shrinking the partially identified set. Recent work has shown that covariate-assisted PI sets can be…

早期临床试验中兼顾风险的情境多臂老虎机AI 解读

Early-phase clinical trials face the challenge of selecting optimal drug doses that balance safety and efficacy due to uncertain dose-response relationships and varied participant characteristics. Traditional randomized dose allocation often exposes participants to sub-optimal doses by not considering individual covariates, necessitating larger sample sizes and prolonging drug development. This paper introduces a risk-inclusive contextual bandit algorithm that utilizes…