每日简报

基于常微分方程的非线性混合效应模型的变分自编码器推断AI 解读

We propose a variational autoencoder (VAE) approach for parameter estimation in nonlinear mixed-effects models based on ordinary differential equations (NLME-ODEs) using longitudinal data from multiple subjects. In moderate dimensions, likelihood-based inference via the stochastic approximation EM algorithm (SAEM) is widely used, but it relies on Markov Chain Monte-Carlo (MCMC) to approximate subject-specific posteriors. As model complexity increases or observations per…

基于地标超级模型与提升树的时间依赖协变量事件史分析AI 解读

We propose a nonparametric method for dynamic prediction in event history analysis with high-dimensional, time-dependent covariates. The approach estimates future conditional hazards by combining landmarking supermodels with gradient boosted trees. Unlike joint modeling or Cox landmarking models, the proposed estimator flexibly captures interactions and nonlinear effects without imposing restrictive parametric assumptions or requiring the covariate process to be Markovian.…

通过 Wasserstein 生成对抗网络恢复反事实分布AI 解读

Standard Distributional Synthetic Controls (DSC) estimate counterfactual distributions by minimizing the Euclidean $L_2$ distance between quantile functions. We demonstrate that this geometric reliance renders estimators fragile: they lack informative gradients under support mismatch and produce structural artifacts when outcomes are multimodal. This paper proposes a robust estimator grounded in Optimal Transport (OT). We construct the synthetic control by minimizing the…

ARMAr-LASSO：缓解预测变量序列相关对 LASSO 的影响AI 解读

We explore estimation and forecast accuracy for sparse linear models, focusing on scenarios where both predictors and errors carry serial correlations. We establish a clear link between predictor serial correlation and the performance of the LASSO, showing that even orthogonal or weakly correlated stationary AR processes can lead to significant spurious correlations due to their serial correlations. To address this challenge, we propose a novel approach named ARMAr-LASSO…

变系数的 Wald 推断AI 解读

We present simple to implement Wald-type statistics that deliver a general nonparametric inference theory for linear restrictions on varying coefficients in a range of regression models allowing for cross-sectional or spatial dependence. We provide a general central limit theorem that covers a broad range of error spatial dependence structures, allows for a degree of misspecification robustness via nonparametric spatial weights and permits inference on both varying…

利用扩展传染病模型进行因果推断AI 解读

Epidemic models describe the evolution of a communicable disease over time. These models are often modified to include the effects of interventions (control measures) such as vaccination, social distancing, school closings etc. Many such models were proposed during the COVID-19 epidemic. Inevitably these models are used to answer the question: What is the effect of the intervention on the epidemic? These models can either be interpreted as data generating models describing…

结果随机缺失时的有效双重差分估计AI 解读

The Difference-in-Differences (DiD) method is a fundamental tool for causal inference, yet its application is often complicated by missing data. Although recent work has developed robust DiD estimators for complex settings like staggered treatment adoption, these methods typically assume complete data and fail to address the critical challenge of outcomes that are missing at random (MAR) -- a common problem that invalidates standard estimators. We develop a rigorous…