Prenatal alcohol exposure and child cognition: semi-continuous exposures, causal inference and evidence synthesis
产前酒精暴露与儿童认知:半连续暴露的因果推断与证据综合
We address the challenge of causal inference status and the dose-response effects with a semi-continuous exposure. A two-stage approach is proposed using estimating equation for multiple outcomes with large sample properties derived for the resulting estimators. Homogeneity tests are developed to assess whether causal effects of exposure status and the dose-response effects are the same across multiple outcomes. A global homogeneity test is also developed to assess whether…