Two-phase validation sampling via principal components to improve efficiency in multi-model estimation from error-prone biomedical databases
基于主成分的两阶段验证抽样:提升多模型估计效率
Two-phase sampling offers a cost-effective way to validate error-prone covariate measurements in biomedical databases. Inexpensive or easy-to-obtain information is collected for the entire study in Phase I. Then, a subset of patients undergoes cost-intensive validation (e.g., expert chart review) to collect more accurate data in Phase II. When balancing primary and secondary analyses, competing models and priorities can result in poorly defined objectives for the most…