每日简报

面向生物样本库规模高维组学数据的单变量引导稀疏回归AI 解读

We present a scalable framework for computing polygenic risk scores (PRS) in high-dimensional genomic settings using the recently introduced Univariate-Guided Sparse Regression (uniLasso). UniLasso is a two-stage penalized regression procedure that leverages univariate coefficients and magnitudes to stabilize feature selection and enhance interpretability. Building on its theoretical and empirical advantages, we adapt uniLasso for application to the UK Biobank, a…

Wasserstein 自回归的诊断检验AI 解读

Wasserstein autoregression provides a robust framework for modeling serial dependence among probability distributions, with wide-ranging applications in economics, finance, and climate science. In this paper, we develop portmanteau-type diagnostic tests for assessing the adequacy of Wasserstein autoregressive models. By defining autocorrelation functions for model errors and residuals in the Wasserstein space, we construct two related tests: one analogous to the classical…

因果推断的设计型理论AI 解读

Causal inference, as a major research area in statistics and data science, plays a central role across diverse fields such as medicine, economics, education, and the social sciences. Design-based causal inference begins with randomized experiments and emphasizes conducting statistical inference by leveraging the known randomization mechanism, thereby enabling identification and estimation of causal effects under weak model dependence. Grounded in the seminal works of Fisher…

计算流体动力学模拟中的初始暂态检测与收敛统计评估AI 解读

Time series data often contain initial transient periods before reaching a stable state, posing challenges in analysis and interpretation. In this paper, we propose a novel approach to detect and estimate the end of the initial transient in time series data. Our method leverages the reversal mean standard error (RMSE) as a metric for assessing the stability of the data. Additionally, we employ fractional filtering techniques to enhance the detection accuracy by filtering out…

工具变量模型中不可观测的异质溢出效应AI 解读

This paper develops a general framework for identifying causal effects in settings with spillovers, where both outcomes and endogenous treatment decisions are influenced by peers within a known group. It introduces the generalized local average controlled spillover and direct effects (LACSEs and LACDEs), which extend the local average treatment effect framework to settings with spillovers and establish sufficient conditions for their point identification without restricting…

部分数据缺失下的广义矩估计AI 解读

We consider a generalized method of moments framework in which a part of the data vector is missing for some units in a completely unrestricted, potentially endogenous way. In this setup, the parameters of interest are usually only partially identified. We characterize the identified set for such parameters using the support function of the convex set of moment predictions consistent with the data. This identified set is sharp, valid for both continuous and discrete data,…

有限重叠下因果推断的敏感性方法AI 解读

Limited overlap between treated and control groups is a key challenge in observational analysis. Standard approaches like trimming importance weights can reduce variance but introduce a fundamental bias. We propose a sensitivity framework for contextualizing findings under limited overlap, where we assess how irregular the outcome function has to be in order for the main finding to be invalidated. Our approach is based on worst-case confidence bounds on the bias introduced…

基于设计的嵌套工具变量分析AI 解读

Two binary instrumental variables (IVs) are nested if individuals who comply under one binary IV also comply under the other. This situation often arises when the two IVs represent different intensities of encouragement or discouragement to take the treatment, with one stronger than the other. In a nested IV structure, treatment effects can be identified for two latent subgroups: always-compliers and switchers. Always-compliers are individuals who comply even under the…

仅用两个参数和少量数据预测登革热病例：美国佛罗里达州2022—2023年疫情AI 解读

Reliable and timely dengue predictions can provide an actionable lead time for targeted vector control and clinical preparedness, reducing preventable disease and health-system costs in at-risk communities. However, many forecasting approaches depend on site-specific covariates and entomological surveillance, which limits portability to data-sparse settings. In this work, we mathematically prove that a parabolic ICC structure, previously established for the basic SIR model,…

TabPFN：一个模型能否包办所有任务？AI 解读

Hollmann et al. (Nature 637 (2025) 319-326) recently introduced TabPFN, a transformer-based deep learning model for regression and classification on tabular data, which they claim "outperforms all previous methods on datasets with up to 10,000 samples by a wide margin, using substantially less training time." Furthermore, they have called TabPFN a "foundation model" for tabular data, as it can support "data generation, density estimation, learning reusable embeddings and…

多变量贝叶斯机器学习模型的情景分析AI 解读

We present an econometric framework that adapts tools for scenario analysis, such as variants of conditional forecasts and generalized impulse responses, for use with dynamic nonparametric models. The proposed algorithms are based on predictive simulation and sequential Monte Carlo methods. Their utility is demonstrated with three applications: (1) conditional forecasts based on stress test scenarios, measuring (2) macroeconomic risk under varying financial stress, and…