每日简报

正值性假设违反时的倾向得分加权方法教程AI 解读

Violations of the positivity assumption can render conventional causal estimands unidentifiable, including the average treatment effect (ATE), the average treatment effect on the treated (ATT), and the average treatment effect on the controls (ATC). Shifting the inferential focus to their alternative counterparts -- the weighted ATE (WATE), the weighted ATT (WATT), and the weighted ATC (WATC) -- offers valuable insights into treatment effects while preserving internal…

因果图不确定时的有效调整集选择AI 解读

Precise knowledge of causal directed acyclic graphs (DAGs) is assumed for standard approaches towards valid adjustment set selection for unbiased estimation, but in practice, the DAG is often inferred from data or expert knowledge, introducing uncertainty. We present techniques to identify valid adjustment sets despite potential errors in the estimated causal graph. Specifically, we assume that only the skeleton of the DAG is known. Under a Bayesian framework, we place a…

通过数据复用降低医疗 AI 模型随机试验成本AI 解读

Randomized controlled trials (RCTs) are indispensable for establishing the clinical value of medical artificial-intelligence (AI) tools, yet their high cost and long timelines hinder timely validation as new models emerge rapidly. Here, we propose BRIDGE, a data-reuse RCT design for AI-based risk models. AI risk models support a broad range of interventions, including screening, treatment selection, and clinical alerts. BRIDGE trials recycle participant-level data from…