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用贝叶斯决策树集成估计异质性因果中介效应AI 解读

The causal inference literature has increasingly recognized that targeting treatment effect heterogeneity can lead to improved scientific understanding and policy recommendations. Similarly, studying the causal pathway connecting the treatment to the outcome can be useful. We address these problems in the context of causal mediation analysis . We introduce a varying coefficient model based on Bayesian additive regression trees to estimate and regularize heterogeneous causal…

通过外推进行安全政策学习：审前风险评估应用AI 解读

Algorithmic recommendations and decisions have become ubiquitous in today’s society. Many of these data-driven policies, especially in the realm of public policy, are based on known, deterministic rules to ensure their transparency and interpretability. We examine a particular case of algorithmic pre-trial risk assessments in the US criminal justice system, which provide deterministic classification scores and recommendations to help judges make release decisions. Our goal…

存在未测量混杂时广义线性模型的同时推断AI 解读

Tens of thousands of simultaneous hypothesis tests are routinely performed in genomic studies to identify differentially expressed genes. However, due to unmeasured confounders, many standard statistical approaches may be substantially biased. This article investigates the large-scale hypothesis testing problem for multivariate generalized linear models in the presence of confounding effects. Under arbitrary confounding mechanisms, we propose a unified statistical estimation…

复杂区域上分位数空间变系数模型的估计与推断AI 解读

This article presents a flexible quantile spatially varying coefficient model (QSVCM) for the regression analysis of spatial data. The proposed model enables researchers to assess the dependence of conditional quantiles of the response variable on covariates while accounting for spatial nonstationarity. Our approach facilitates learning and interpreting heterogeneity in spatial data distributed over complex or irregular domains. We introduce a quantile regression method that…

高维谱密度矩阵的统计推断AI 解读

The spectral density matrix is a fundamental object of interest in time series analysis, and it encodes both contemporary and dynamic linear relationships between component processes of the multivariate system. In this paper we develop novel inference procedures for the spectral density matrix in the high-dimensional setting. Specifically, we introduce a new global testing procedure to test the nullity of the cross-spectral density for a given set of frequencies and across…

高维时间序列的频域统计推断AI 解读

Analyzing time series in the frequency domain enables the development of powerful tools for investigating the second-order characteristics of multivariate processes. Parameters like the spectral density matrix and its inverse, the coherence or the partial coherence, encode comprehensively the complex linear relations between the component processes of the multivariate system. In this paper, we develop inference procedures for such parameters in a high-dimensional, time…

误设 Copula 模型中的反馈切断AI 解读

In copula models the marginal distributions and copula function are specified separately. We treat these as two modules in a modular Bayesian inference framework, and propose conducting modified Bayesian inference by “cutting feedback”. Cutting feedback limits the influence of potentially misspecified modules in posterior inference. We consider two types of cuts. The first limits the influence of a misspecified copula on inference for the marginals, which is a Bayesian…

重复观测与纵向随机对象的测地线混合效应模型AI 解读

Mixed effect modeling for longitudinal data is challenging when the observed data are random objects, which are complex data taking values in a general metric space without either global linear or local linear (Riemannian) structure. In such settings the classical additive error model and distributional assumptions are unattainable. Due to the rapid advancement of technology, longitudinal data containing complex random objects, such as covariance matrices, data on Riemannian…

通过乐观数据重加权增强似然稳健性AI 解读

Likelihood-based inferences have been remarkably successful in wide-spanning application areas. However, even after due diligence in selecting a good model for the data at hand, there is inevitably some amount of model misspecification: outliers, data contamination or inappropriate parametric assumptions such as Gaussianity mean that most models are at best rough approximations of reality. A significant practical concern is that for certain inferences, even small amounts of…

基于分位数函数的分布型结局回归及心率与活动量应用AI 解读

Modern clinical and epidemiological studies widely employ wearables to record parallel streams of real-time data on human physiology and behavior. With recent advances in distributional data analysis, these high-frequency data are now often treated as distributional observations resulting in novel regression settings. Motivated by these modeling setups, we develop a distributional outcome regression via quantile functions (DORQF) that expands existing literature with three…

通过自适应合并实现纵向网络的高效估计AI 解读

Longitudinal networks consist of sequences of temporal edges among multiple nodes, where the temporal edges are observed in real-time. They have become ubiquitous with the rise of online social platforms and e-commerce, but largely under-investigated in the literature. In this article, we propose an efficient estimation framework for longitudinal networks, leveraging strengths of adaptive network merging, tensor decomposition, and point processes. It merges neighboring…

快速信号区域检测及其全基因组关联研究应用AI 解读

Research on the localization of the genetic basis associated with diseases or traits has been widely conducted in the last few decades. Scan methods have been developed for region-based analysis in whole-genome association studies, helping us better understand how genetics influences human diseases or traits, especially when the aggregated effects of multiple causal variants are present. In this paper, we propose a fast and effective algorithm coupling with high-dimensional…

用于筛估计的相位型分布AI 解读

In many semiparametric models, the infinite-dimensional parameter of direct interest is a probability density, but its nonparametric estimation is usually difficult in the presence of incomplete data. To address this issue, this study promotes phase-type distributions as a method of sieve. Phase-type distributions are dense in the space of nonnegative distributions, closed under minimum, maximum, and convolution, and compatible with the accelerated failure time model. This…

基于弱依赖随机过程极大值的高维变量聚类AI 解读

We propose a new class of models for variable clustering called Asymptotic Independent block (AI-block) models, which defines population-level clusters based on the independence of the maxima of a multivariate stationary mixing random process among clusters. This class of models is identifiable, meaning that there exists a maximal element with a partial order between partitions, allowing for statistical inference. We also present an algorithm depending on a tuning parameter…

高维期望短缺回归AI 解读

Expected shortfall is defined as the average over the tail below (or above) a certain quantile of a probability distribution. Expected shortfall regression provides powerful tools for learning the relationship between a response variable and a set of covariates while exploring the heterogeneous effects of the covariates. In the health disparity research, for example, the lower/upper tail of the conditional distribution of a health-related outcome, given high-dimensional…

目标处理效应的联邦自适应因果估计AI 解读

Federated learning of causal estimands may greatly improve estimation efficiency by leveraging data from multiple study sites, but robustness to heterogeneity and model misspecifications is vital for ensuring validity. We develop a Federated Adaptive Causal Estimation (FACE) framework to incorporate heterogeneous data from multiple sites to provide treatment effect estimation and inference for a flexibly specified target population of interest. FACE accounts for site-level…

U 统计量缩减：高阶精确风险控制与统计计算权衡AI 解读

U-statistics play central roles in many statistical learning tools but face the haunting issue of scalability. Despite extensive research on accelerating computation by U-statistic reduction, existing results almost exclusively focused on power analysis. Little work addresses risk control accuracy, which requires distinct and much more challenging techniques. In this paper, we establish the first statistical inference procedure with provably higher-order accurate risk…

利用球协方差排序与聚合识别脑连接相关遗传变异AI 解读

Understanding the genetic architecture of brain functions is essential to clarify the biological etiologies of behavioral and psychiatric disorders. Functional connectivity, representing pairwise correlations of neural activities between brain regions, is moderately heritable. Current methods to identify single nucleotide polymorphisms (SNPs) linked to functional connectivity either neglect the complex structure of functional connectivity or fail to control false…

时间序列数据的高维 Knockoffs 推断AI 解读

We make some initial attempt to establish the theoretical and methodological foundation for the model-X knockoffs inference for time series data. We suggest the method of time series knockoffs inference (TSKI) by exploiting the ideas of subsampling and e-values to address the difficulty caused by the serial dependence. We also generalize the robust knockoffs inference in Barber, Candès, and Samworth to the time series setting to relax the assumption of known covariate…

联邦元学习的稳健推断AI 解读

Synthesizing information from multiple data sources is critical to ensure knowledge generalizability. Integrative analysis of multi-source data is challenging due to the heterogeneity across sources and data-sharing constraints due to privacy concerns. In this paper, we consider a general robust inference framework for federated meta-learning of data from multiple sites, enabling statistical inference for the prevailing model, defined as the one matching the majority of the…

零膨胀与离群计数的稳健贝叶斯建模：理论稳健性与高效计算AI 解读

Count data with zero inflation and large outliers are ubiquitous in many scientific applications. However, posterior analysis under a standard statistical model, such as Poisson or negative binomial distribution, is sensitive to such contamination. This study introduces a novel framework for Bayesian modeling of counts that is robust to both zero inflation and large outliers. In doing so, we introduce rescaled beta distribution and adopt it to absorb undesirable effects from…

高维数据的自适应检验AI 解读

In this article, we propose a class of Lq-norm based U-statistics for a family of global testing problems related to high-dimensional data. This includes testing of mean vector and its spatial sign, simultaneous testing of linear model coefficients, and testing of component-wise independence for high-dimensional observations, among others. Under the null hypothesis, we derive asymptotic normality and independence between Lq-norm based U-statistics for several qs under mild…

匹配观察研究中隐蔽偏差分位数的敏感性分析AI 解读

Causal conclusions from observational studies may be sensitive to unmeasured confounding. In such cases, a sensitivity analysis is often conducted, which tries to infer the minimum amount of hidden biases or the minimum strength of unmeasured confounding needed in order to explain away the observed association between treatment and outcome. If the needed bias is large, then the treatment is likely to have significant effects. The Rosenbaum sensitivity analysis is a modern…

偏好建模：排名与评分的贝叶斯有限混合之混合模型AI 解读

Rankings and ratings are commonly used to express preferences but provide distinct and complementary information.Rankings give ordinal and scale-free comparisons but lack granularity; ratings provide cardinal and granular assessments but may be highly subjective or inconsistent.Collecting and analyzing rankings and ratings jointly has not been performed until recently due to a lack of principled methods.In this work, we propose a flexible, joint statistical model for…