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多参数非参数融合学习：结合数据深度与置信分布AI 解读

Fusion learning refers to synthesizing inferences from multiple sources or studies to make a more effective inference and prediction than from any individual source or study alone. Most existing methods for synthesizing inferences rely on parametric model assumptions, such as normality, which often do not hold in practice. We propose a general nonparametric fusion learning framework for synthesizing inferences for multiparameters from different studies. The main tool…

配对随机实验中的推断AI 解读

This article studies inference for the average treatment effect in randomized controlled trials where treatment status is determined according to a “matched pairs” design. By a “matched pairs” design, we mean that units are sampled iid from the population of interest, paired according to observed, baseline covariates and finally, within each pair, one unit is selected at random for treatment. This type of design is used routinely throughout the sciences, but fundamental…

网络函数型变系数模型AI 解读

We consider functional responses with network dependence observed for each individual at irregular time points. To model both the interindividual dependence and within-individual dynamic correlation, we propose a network functional varying coefficient (NFVC) model. The response of each individual is characterized by a linear combination of responses from its connected nodes and its exogenous covariates. All the model coefficients are allowed to be time dependent. The NFVC…

高维数据变点的自适应推断AI 解读

In this article, we propose a class of test statistics for a change point in the mean of high-dimensional independent data. Our test integrates the U-statistic based approach in a recent work by Wang et al. and the Lq-norm based high-dimensional test in a recent work by He et al., and inherits several appealing features such as being tuning parameter free and asymptotic independence for test statistics corresponding to even q’s. A simple combination of test statistics…

高维响应线性模型中的线性假设检验AI 解读

In this paper, we propose a new projection test for linear hypotheses on regression coefficient matrices in linear models with high dimensional responses. We systematically study the theoretical properties of the proposed test. We first derive the optimal projection matrix for any given projection dimension to achieve the best power and provide an upper bound for the optimal dimension of projection matrix. We further provide insights into how to construct the optimal…

核常微分方程AI 解读

Ordinary differential equation (ODE) is widely used in modeling biological and physical processes in science. In this article, we propose a new reproducing kernel-based approach for estimation and inference of ODE given noisy observations. We do not assume the functional forms in ODE to be known, or restrict them to be linear or additive, and we allow pairwise interactions. We perform sparse estimation to select individual functionals, and construct confidence intervals for…

结合目标总体汇总统计与源总体个体数据的事件发生风险外推AI 解读

Predicting risks of chronic diseases has become increasingly important in clinical practice. When a prediction model is developed in a cohort, there is a great interest to apply the model to other cohorts. Due to potential discrepancy in baseline disease incidences between different cohorts and shifts in patient composition, the risk predicted by the model built in the source cohort often under- or over-estimates the risk in a new cohort. In this article, we assume the…

时间序列模型的稳健两步小波推断AI 解读

) models with additional stochastic processes are increasingly used for data analysis in biology, ecology, engineering, and economics. Inference on and/or prediction from these models can be highly challenging: (i) the data may contain outliers that can adversely affect the estimation procedure; (ii) the computational complexity can become prohibitive when the time series are extremely large; (iii) model selection adds another layer of (computational) complexity; and (iv)…

本福特定律的刻画与检验AI 解读

Benford’s law defines a probability distribution for patterns of significant digits in real numbers. When the law is expected to hold for genuine observations, deviation from it can be taken as evidence of possible data manipulation. We derive results on a transform of the significand function that provide motivation for new tests of conformance to Benford’s law exploiting its sum-invariance characterization. We also study the connection between sum invariance of the first…

嵌套误差回归模型中经验最佳线性无偏预测的渐近理论AI 解读

In this article we derive the asymptotic distribution of estimated best linear unbiased predictors (EBLUPs) of the random effects in a nested error regression model. Under very mild conditions which do not require the assumption of normality, we show that asymptotically the distribution of the EBLUPs as both the number of clusters and the cluster sizes diverge to infinity is the convolution of the true distribution of the random effects and a normal distribution. This result…

预先多重检验估计及其在多样本协方差估计中的应用AI 解读

Multisample covariance estimation—that is, estimation of the covariance matrices associated with k distinct populations—is a classical problem in multivariate statistics. A common solution is to base estimation on the outcome of a test that these covariance matrices show some given pattern. Such a preliminary test may, for example, investigate whether or not the various covariance matrices are equal to each other (test of homogeneity), or whether or not they have common…

利用布尔矩阵逻辑检验中介效应AI 解读

A central question in high-dimensional mediation analysis is to infer the significance of individual mediators. The main challenge is that the total number of potential paths that go through any mediator is super-exponential in the number of mediators. Most existing mediation inference solutions either explicitly impose that the mediators are conditionally independent given the exposure, or ignore any potential directed paths among the mediators. In this article, we propose…

一致稀疏深度学习：理论与计算AI 解读

Deep learning has been the engine powering many successes of data science. However, the deep neural network (DNN), as the basic model of deep learning, is often excessively over-parameterized, causing many difficulties in training, prediction and interpretation. We propose a frequentist-like method for learning sparse DNNs and justify its consistency under the Bayesian framework: the proposed method could learn a sparse DNN with at most O(n/ log (n)) connections and nice…

无需估计非可忽略缺失机制的通用估计程序AI 解读

We consider the estimation problem in a regression setting where the outcome variable is subject to nonignorable missingness and identifiability is ensured by the shadow variable approach. We propose a versatile estimation procedure where modeling of missingness mechanism is completely bypassed. We show that our estimator is easy to implement and we derive the asymptotic theory of the proposed estimator. We also investigate some alternative estimators under different…

普通最小二乘二次泛函的中等维度推断AI 解读

Statistical inferences for quadratic functionals of linear regression parameter have found wide applications including signal detection, global testing, inferences of error variance and fraction of variance explained. Classical theory based on ordinary least squares estimator works perfectly in the low-dimensional regime, but fails when the parameter dimension pn grows proportionally to the sample size n. In some cases, its performance is not satisfactory even when n≥5pn.…

含分类变量的变量选择：模型选择视角AI 解读

In the context of a Gaussian multiple regression model, we address the problem of variable selection when in the list of potential predictors there are factors, that is, categorical variables. We adopt a model selection perspective, that is, we approach the problem by constructing a class of models, each corresponding to a particular selection of active variables. The methodology is Bayesian and proceeds by computing the posterior probability of each of these models. We…

高维线性混合效应模型的推断：拟似然方法AI 解读

Linear mixed-effects models are widely used in analyzing clustered or repeated measures data. We propose a quasi-likelihood approach for estimation and inference of the unknown parameters in linear mixed-effects models with high-dimensional fixed effects. The proposed method is applicable to general settings where the dimension of the random effects and the cluster sizes are possibly large. Regarding the fixed effects, we provide rate optimal estimators and valid inference…

用于分布式估计与推断的一阶牛顿型估计量AI 解读

This article studies distributed estimation and inference for a general statistical problem with a convex loss that could be nondifferentiable. For the purpose of efficient computation, we restrict ourselves to stochastic first-order optimization, which enjoys low per-iteration complexity. To motivate the proposed method, we first investigate the theoretical properties of a straightforward divide-and-conquer stochastic gradient descent approach. Our theory shows that there…

深度复合空间模型AI 解读

Spatial processes with nonstationary and anisotropic covariance structure are often used when modeling, analyzing, and predicting complex environmental phenomena. Such processes may often be expressed as ones that have stationary and isotropic covariance structure on a warped spatial domain. However, the warping function is generally difficult to fit and not constrained to be injective, often resulting in “space-folding.” Here, we propose modeling an injective warping…

利用参数化决策分析实现快速、最优与目标导向预测AI 解读

Prediction is critical for decision-making under uncertainty and lends validity to statistical inference. With targeted prediction, the goal is to optimize predictions for specific decision tasks of interest, which we represent via functionals. Although classical decision analysis extracts predictions from a Bayesian model, these predictions are often difficult to interpret and slow to compute. Instead, we design a class of parameterized actions for Bayesian decision…

含协变量的双成分混合模型AI 解读

In this article, we study a generalization of the two-groups model in the presence of covariates—a problem that has recently received much attention in the statistical literature due to its applicability in multiple hypotheses testing problems. The model we consider allows for infinite dimensional parameters and offers flexibility in modeling the dependence of the response on the covariates. We discuss the identifiability issues arising in this model and systematically study…

主成分分析的分布式估计：扩展特征子空间分析AI 解读

The growing size of modern datasets brings many challenges to the existing statistical estimation approaches, which calls for new distributed methodologies. This article studies distributed estimation for a fundamental statistical machine learning problem, principal component analysis (PCA). Despite the massive literature on top eigenvector estimation, much less is presented for the top-L-dim (L > 1) eigenspace estimation, especially in a distributed manner. We propose a…

Wald 检验中的 Hauck–Donner 效应：检测、临界点与参数空间刻画AI 解读

The Wald test remains ubiquitous in statistical practice despite shortcomings such as its inaccuracy in small samples and lack of invariance under reparameterization. This article develops on another but lesser-known shortcoming called the Hauck–Donner effect (HDE) whereby a Wald test statistic is no longer monotone increasing as a function of increasing distance between the parameter estimate and the null value. Resulting in an upward biased p-value and loss of power, the…

含噪、稀疏及片段化函数数据的同步配准与估计：贝叶斯框架AI 解读

In many applications, smooth processes generate data that is recorded under a variety of observational regimes, including dense sampling and sparse or fragmented observations that are often contaminated with error. The statistical goal of registering and estimating the individual underlying functions from discrete observations has thus far been mainly approached sequentially without formal uncertainty propagation, or in an application-specific manner by pooling information…