Nonparametric modelling of continuous-time Markov chains with scalable exact and approximate gradients
连续时间马尔可夫链的非参数建模:可扩展的精确与近似梯度
Abstract Inferring the infinitesimal rates of continuous-time Markov chains (CTMCs) is a central challenge in many scientific domains. This task is hindered by 3 factors: quadratic growth in the number of rates as the CTMC state space expands, strong dependencies among rates, and incomplete information for many transitions. We introduce a new Bayesian framework that flexibly models CTMC rates by incorporating covariates through Gaussian processes. This approach improves…