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Non-parametric Methods for Doubly Robust Estimation of Continuous Treatment Effects

连续处理效应双重稳健估计的非参数方法

Summary Continuous treatments (e.g. doses) arise often in practice, but many available causal effect estimators are limited by either requiring parametric models for the effect curve, or by not allowing doubly robust covariate adjustment. We develop a novel kernel smoothing approach that requires only mild smoothness assumptions on the effect curve and still allows for misspecification of either the treatment density or outcome regression. We derive asymptotic properties and…

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On Estimation of Optimal Treatment Regimes for Maximizing t -Year Survival Probability

最大化 t 年生存概率的最优治疗策略估计

Summary A treatment regime is a deterministic function that dictates personalized treatment based on patients’ individual prognostic information. There is increasing interest in finding optimal treatment regimes, which determine treatment at one or more treatment decision points to maximize expected long-term clinical outcomes, where larger outcomes are preferred. For chronic diseases such as cancer or human immunodeficiency virus infection, survival time is often the…

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Injectivity of a class of integral operators with compactly supported kernels

一类紧支撑核积分算子的单射性

Injectivity of integral operators is related to completeness conditions of their corresponding kernel functions. Completeness provides a useful way of obtaining nonparametric identification in various models including nonparametric regression models with instrumental variables, nonclassical measurement error models, and auction models, etc. However, the condition is quite abstract for empirical work and lacks a proper economic interpretation. We rely on known results…

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UNIFORM CONVERGENCE RATES OF KERNEL-BASED NONPARAMETRIC ESTIMATORS FOR CONTINUOUS TIME DIFFUSION PROCESSES: A DAMPING FUNCTION APPROACH

连续时间扩散过程核非参数估计的一致收敛速率:阻尼函数方法

In this paper, we derive uniform convergence rates of nonparametric estimators for continuous time diffusion processes. In particular, we consider kernel-based estimators of the Nadaraya–Watson type, introducing a new technical device called a damping function . This device allows us to derive sharp uniform rates over an infinite interval with minimal requirements on the processes: The existence of the moment of any order is not required and the boundedness of relevant…

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ADAPTIVE BAYESIAN ESTIMATION OF CONDITIONAL DENSITIES

条件密度的自适应贝叶斯估计

We consider a nonparametric Bayesian model for conditional densities. The model is a finite mixture of normal distributions with covariate dependent multinomial logit mixing probabilities. A prior for the number of mixture components is specified on positive integers. The marginal distribution of covariates is not modeled. We study asymptotic frequentist behavior of the posterior in this model. Specifically, we show that when the true conditional density has a certain…

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Set-Based Tests for the Gene–Environment Interaction in Longitudinal Studies

纵向研究中基因与环境交互的集合检验

We propose a generalized score type test for set-based inference for gene-environment interaction with longitudinally measured quantitative traits. The test is robust to misspecification of within subject correlation structure and has enhanced power compared to existing alternatives. Unlike tests for marginal genetic association, set-based tests for gene-environment interaction face the challenges of a potentially misspecified and high-dimensional main effect model under the…

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MWPCR: Multiscale Weighted Principal Component Regression for High-Dimensional Prediction

MWPCR:用于高维预测的多尺度加权主成分回归

We propose a multiscale weighted principal component regression (MWPCR) framework for the use of high dimensional features with strong spatial features (e.g., smoothness and correlation) to predict an outcome variable, such as disease status. This development is motivated by identifying imaging biomarkers that could potentially aid detection, diagnosis, assessment of prognosis, prediction of response to treatment, and monitoring of disease status, among many others. The…

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An Effective Semiparametric Estimation Approach for the Sufficient Dimension Reduction Model

充分降维模型的一种有效半参数估计方法

In the exploratory data analysis, the sufficient dimension reduction model has been widely used to characterize the conditional distribution of interest. Different from the existing approaches, our main achievement is to simultaneously estimate two essential elements, basis and structural dimension, of the central subspace and the bandwidth of a kernel distribution estimator through a single estimation criterion. With an appropriate order of kernel function, the proposed…

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Generalized Additive Models for Gigadata: Modeling the U.K. Black Smoke Network Daily Data

海量数据的广义加性模型:英国黑烟监测网日度数据建模

We develop scalable methods for fitting penalized regression spline based generalized additive models with of the order of 104 coefficients to up to 108 data. Computational feasibility rests on: (i) a new iteration scheme for estimation of model coefficients and smoothing parameters, avoiding poorly scaling matrix operations; (ii) parallelization of the iteration’s pivoted block Cholesky and basic matrix operations; (iii) the marginal discretization of model covariates to…

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Identification and estimation of a bidding model for electronic auctions

电子拍卖竞价模型的识别与估计

Because of discrete bid increments, bidders at electronic auctions engage in shading instead of revealing their valuations, which would occur under the commonly assumed second-price rule. We demonstrate that misspecifying the pricing rule can lead to biased estimates of the latent valuation distribution, and then explore identification and estimation of a model with a correctly specified pricing rule. A further challenge to econometricians is that only a lower bound on the…

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Continuous Auto-Regressive Moving Average Random Fields on Rn

实数空间中的连续自回归移动平均随机场

Summary We define an isotropic Lévy-driven continuous auto-regressive moving average CARMA(p, q) random field on Rn as the integral of a radial CARMA kernel with respect to a Lévy sheet. Such fields constitute a parametric family characterized by an auto-regressive polynomial a and a moving average polynomial b having zeros in both the left and the right complex half-planes. They extend the well-balanced Ornstein–Uhlenbeck process of Schnurr and Woerner to a well-balanced…

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Nonlinear sufficient dimension reduction for functional data

函数型数据的非线性充分降维

We propose a general theory and the estimation procedures for nonlinear sufficient dimension reduction where both the predictor and the response may be random functions. The relation between the response and predictor can be arbitrary and the sets of observed time points can vary from subject to subject. The functional and nonlinear nature of the problem leads to construction of two functional spaces: the first representing the functional data, assumed to be a Hilbert space,…

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Randomized sketches for kernels: Fast and optimal nonparametric regression

核方法的随机压缩:快速且最优的非参数回归

Kernel ridge regression (KRR) is a standard method for performing nonparametric regression over reproducing kernel Hilbert spaces. Given $n$ samples, the time and space complexity of computing the KRR estimate scale as $\mathcal{O}(n^{3})$ and $\mathcal{O}(n^{2})$, respectively, and so is prohibitive in many cases. We propose approximations of KRR based on $m$-dimensional randomized sketches of the kernel matrix, and study how small the projection dimension $m$ can be chosen…

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BIAS CORRECTION OF SEMIPARAMETRIC LONG MEMORY PARAMETER ESTIMATORS VIA THE PREFILTERED SIEVE BOOTSTRAP

用预滤波筛自助法修正半参数长记忆估计偏差

This paper investigates bootstrap-based bias correction of semiparametric estimators of the long memory parameter, d , in fractionally integrated processes. The re-sampling method involves the application of the sieve bootstrap to data prefiltered by a preliminary semiparametric estimate of the long memory parameter. Theoretical justification for using the bootstrap technique to bias adjust log periodogram and semiparametric local Whittle estimators of the memory parameter…

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Estimating the Competitive Storage Model with Trending Commodity Prices

商品价格存在趋势时的竞争性储藏模型估计

We present a method to estimate jointly the parameters of a standard commodity storage model and the parameters characterizing the trend in commodity prices. This procedure allows the influence of a possible trend to be removed without restricting the model specification, and allows model and trend selection based on statistical criteria. The trend is modeled deterministically using linear or cubic spline functions of time. The results show that storage models with trend are…

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A Bayesian Multivariate Functional Dynamic Linear Model

贝叶斯多变量函数型动态线性模型

We present a Bayesian approach for modeling multivariate, dependent functional data. To account for the three dominant structural features in the data—functional, time dependent, and multivariate components—we extend hierarchical dynamic linear models for multivariate time series to the functional data setting. We also develop Bayesian spline theory in a more general constrained optimization framework. The proposed methods identify a time-invariant functional basis for the…

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A Sieve Semiparametric Maximum Likelihood Approach for Regression Analysis of Bivariate Interval-Censored Failure Time Data

双变量区间删失失效时间回归的筛半参数极大似然方法

Interval-censored failure time data arise in a number of fields and many authors have discussed various issues related to their analysis. However, most of the existing methods are for univariate data and there exists only limited research on bivariate data, especially on regression analysis of bivariate interval-censored data. We present a class of semiparametric transformation models for the problem and for inference, a sieve maximum likelihood approach is developed. The…

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Multiple testing of local maxima for detection of peaks in random fields

A topological multiple testing scheme is presented for detecting peaks in images under stationary ergodic Gaussian noise, where tests are performed at local maxima of the smoothed observed signals. The procedure generalizes the one-dimensional scheme of [31] to Euclidean domains of arbitrary dimension. Two methods are developed according to two different ways of computing p-values: (i) using the exact distribution of the height of local maxima, available explicitly when the…

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A fixed-bandwidth view of the pre-asymptotic inference for kernel smoothing with time series data

时间序列核平滑预渐近推断的固定带宽视角

This paper develops robust testing procedures for nonparametric kernel methods in the presence of temporal dependence of unknown forms. Based on the fixed-bandwidth asymptotic variance and the pre-asymptotic variance, we propose a heteroskedasticity and autocorrelation robust (HAR) variance estimator that achieves double robustness — it is asymptotically valid regardless of whether the temporal dependence is present or not, and whether the kernel smoothing bandwidth is held…

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The Millennium Peak in Club Convergence: A New Look at Distributional Changes in The Wealth of Nations

俱乐部趋同的千禧年高峰:国家财富分布变化的新观察

Summary This paper proposes an easy‐to‐use nonparametric indicator for club convergence, or convergence within clusters of countries: it measures whether the modes of the gross domestic product (GDP) per capita distribution become more pronounced over time. Relying on changes in the critical bandwidth for unimodality, the indicator is a dynamic extension of concepts from often‐used multimodality tests. Its evolution suggests the new empirical result of a ‘millennium peak’ in…

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Oracally Efficient Estimation and Consistent Model Selection for Auto-Regressive Moving Average Time Series with Trend

带趋势ARMA时间序列的预言效率估计与一致模型选择

Summary Most time series that are encountered in practice contain non-zero trend, yet textbook approaches to time series analysis are typically focused on zero-mean stationary auto-regressive moving average (ARMA) processes. Trend is often estimated by ad hoc methods and subtracted from time series, and the residuals are used as the true ARMA noise for data analysis and inference, including parameter estimation, lag selection and prediction. We propose a theoretically…

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Density estimation in the two-sample problem with likelihood ratio ordering

似然比有序约束下的两样本密度估计

In this paper, we propose a method for estimating the probability density functions in a two-sample problem where the ratio of the densities is monotone. This problem has been widely identified in the literature, but effective solution methods, in which the estimates should be probability densities and the corresponding density ratio should inherit monotonicity, are unavailable. If these conditions are not satisfied, the applications of the resultant density estimates might…

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Case-cohort studies with interval-censored failure time data

区间删失失效时间数据的病例队列研究

The case-cohort design has been widely used as a means of cost reduction in assembling or measuring expensive covariates in large cohort studies. The existing literature on the case-cohort design is mainly focused on right-censored data. In practice, however, the failure time is often subject to interval-censoring; it is known only to fall within some random time interval. In this paper, we consider the case-cohort study design for interval-censored failure time and develop…

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Fractional order statistic approximation for nonparametric conditional quantile inference

非参数条件分位数推断的分数阶次序统计量近似

Using and extending fractional order statistic theory, we characterize the O(n−1) coverage probability error of the previously proposed (Hutson, 1999) confidence intervals for population quantiles using L-statistics as endpoints. We derive an analytic expression for the n−1 term, which may be used to calibrate the nominal coverage level to get O(n−3/2[log(n)]3) coverage error. Asymptotic power is shown to be optimal. Using kernel smoothing, we propose a related method for…

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