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Estimation of sums of random variables: Examples and information bounds

随机变量函数之和的估计:实例与信息界

This paper concerns the estimation of sums of functions of observable and unobservable variables. Lower bounds for the asymptotic variance and a convolution theorem are derived in general finite- and infinite-dimensional models. An explicit relationship is established between efficient influence functions for the estimation of sums of variables and the estimation of their means. Certain “plug-in” estimators are proved to be asymptotically efficient in finite-dimensional…

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PARTIALLY LINEAR MODELS WITH UNIT ROOTS

含单位根的部分线性模型

This paper studies the asymptotic properties of a nonstationary partially linear regression model. In particular, we allow for covariates to enter the unit root (or near unit root) model in a nonparametric fashion, so that our model is an extension of the semiparametric model analyzed in Robinson (1988, Econometrica 56, 931–954). It is proved that the autoregressive parameter can be estimated at rate N even though part of the model is estimated nonparametrically. Unit root…

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Minimum distance estimation for the logistic regression model

Logistic 回归模型的最小距离估计

It is well known that the maximum likelihood fit of the logistic regression parameters can be greatly affected by atypical observations. Several robust alternatives have been proposed. However, if we consider the model from the case-control viewpoint, it is clear that current techniques can exhibit poor behaviour in many common situations. A new robust class of estimation procedures is introduced. The estimators are constructed via a minimum distance approach after…

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Comparison of hierarchical likelihood versus orthodox best linear unbiased predictor approaches for frailty models

脆弱性模型中层级似然与传统最佳线性无偏预测方法的比较

Hierarchical likelihood provides a statistically efficient procedure for frailty models. Recently, a method using the computationally attractive orthodox best linear unbiased predictor has been proposed; this uses Pearson-type estimation. We compare both approaches and discuss their relative merits. With semiparametric frailty models difficulties can arise for the orthodox method, if the number of nuisance parameters increases with the sample size. This difficulty is avoided…

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The accelerated gap times model

加速间隔时间模型

This paper develops a new semiparametric model for the effect of covariates on the conditional intensity of a recurrent event counting process. The model is a transparent extension of the accelerated failure time model for univariate survival data. Estimation of the regression parameter is motivated by semiparametric efficiency considerations, extending the class of weighted log-rank estimating functions originally proposed in Prentice (1978) and subsequently studied in…

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Semiparametric inference in observational duration-response studies, with duration possibly right-censored

治疗时长可能右删失的观察性时长—响应研究中的半参数推断

Once treatment is found to be effective in clinical studies, attention often focuses on optimum or efficacious treatment delivery. In treatment duration-response studies, the optimum treatment delivery refers to the treatment length that optimises the mean response. In many studies, the treatment length is often left to the discretion of an attending investigator or physician but may be abruptly terminated because of treatment-terminating events. Thus, a recommended…

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Semiparametric Box–Cox power transformation models for censored survival observations

删失生存观测的半参数 Box–Cox 幂变换模型

The accelerated failure time model specifies that the logarithm of the failure time is linearly related to the covariate vector without assuming a parametric error distribution. In this paper, we consider the semiparametric Box–Cox transformation model, which includes the above regression model as a special case, to analyse possibly censored failure time observations. Inference procedures for the transformation and regression parameters are proposed via a resampling…

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A semiparametric regression cure model with current status data

This paper considers the analysis of current status data with a cured proportion in the population using a mixture model that combines a logistic regression formulation for the probability of cure with a semiparametric regression model for the time to occurrence of the event. The semiparametric regression model belongs to the flexible class of partly linear models that allows one to explore the possibly nonlinear effect of a certain covariate on the response variable. A…

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Estimated Estimating Equations: Semiparametric Inference for Clustered and Longitudinal Data

估计型估计方程:聚类与纵向数据的半参数推断

Summary We introduce a flexible marginal modelling approach for statistical inference for clustered and longitudinal data under minimal assumptions. This estimated estimating equations approach is semiparametric and the proposed models are fitted by quasi-likelihood regression, where the unknown marginal means are a function of the fixed effects linear predictor with unknown smooth link, and variance–covariance is an unknown smooth function of the marginal means. We propose…

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Frailty Survival Model Analysis of the National Deceased Donor Kidney Transplant Dataset Using Poisson Variance Structures

利用泊松方差结构分析亡故供者肾移植数据的脆弱性生存模型

In a recent study of transplant outcomes, donor age, cerebrovascular accident as the cause of death (CVA), renal insufficiency (serum creatinine >1.5 mg/dL), and history of hypertension have been identified as donor factors associated with elevated risk of kidney transplant failure. It is of great interest to know whether there remain other unmeasured donor factors associated with elevated risk of graft failure. In this article we study a sample of 6,024 deceased donor…

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Locally Efficient Semiparametric Estimators for Generalized Skew-Elliptical Distributions

广义偏斜椭圆分布的局部有效半参数估计

We consider a class of generalized skew-normal distributions that is useful for selection modeling and robustness analysis and derive a class of semiparametric estimators for the location and scale parameters of the central part of the model. We show that these estimators are consistent and asymptotically normal. We present the semiparametric efficiency bound and derive the locally efficient estimator that achieves this bound if the model for the skewing function is…

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Estimation of Long Memory in the Presence of a Smooth Nonparametric Trend

存在平滑非参数趋势时的长记忆估计

We consider semiparametric estimation of the long-memory parameter of a stationary process in the presence of an additive nonparametric mean function. We use a semiparametric Whittle-type estimator, applied to the tapered, differenced series. Because the mean function is not necessarily a polynomial of finite order, no amount of differencing will completely remove the mean. We establish a central limit theorem for the estimator of the memory parameter, assuming that a slowly…

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A Two-Way Semilinear Model for Normalization and Analysis of cDNA Microarray Data

用于 cDNA 微阵列归一化与分析的双向半线性模型

A basic question in analyzing cDNA microarray data is normalization, the purpose of which is to remove systematic bias in the observed expression values by establishing a normalization curve across the whole dynamic range. A proper normalization procedure ensures that the normalized intensity ratios provide meaningful measures of relative expression levels. We propose a two-way semilinear model (TW–SLM) for normalization and analysis of microarray data. This method does not…

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Semilinear High-Dimensional Model for Normalization of Microarray Data

微阵列数据归一化的半线性高维模型

Normalization of microarray data is essential for removing experimental biases and revealing meaningful biological results. Motivated by a problem of normalizing microarray data, a semilinear in-slide model (SLIM) has been proposed. To aggregate information from other arrays, SLIM is generalized to account for across-array information, resulting in an even more dynamic semiparametric regression model. This model can be used to normalize microarray data even when there is no…

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The Profile Sampler

剖面似然采样器

We consider frequentist inference for the parametric component θ separately from the nuisance parameter η in semiparametric models based on sampling from the posterior of the profile likelihood. We prove that this procedure gives a first-order–correct approximation to the maximum likelihood estimator and consistent estimation of the efficient Fisher information for θ, without computing derivatives or using complicated numerical approximations. An exact Bayesian…

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Inference for a Class of Transformed Hazards Models

一类变换风险率模型的统计推断

A new class of transformed hazard rate models is considered that contains both the multiplicative hazards model and the additive hazards model as special cases. The sieve maximum likelihood estimators are derived for the model parameters, and the estimators for the regression coefficients are shown to be consistent and asymptotically normal with variance achieving the semiparametric efficiency bound. Simulation studies are conducted to examine the small-sample properties of…

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Semiparametric Regression Analysis of Longitudinal Data With Informative Observation Times

信息性观测时点下纵向数据的半参数回归分析

Statistical analysis of longitudinal data has been discussed by many authors, and a number of methods have been proposed. Most of the research have focused on situations where observation times are independent of or carry no information about the response variable and therefore rely on conditional inference procedures given the observation times. This article considers a different situation, where the independence assumption may not hold; that is, the observation times may…

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Semiparametric Bayesian inference in multiple equation models

多方程模型中的半参数贝叶斯推断

Abstract This paper outlines an approach to Bayesian semiparametric regression in multiple equation models which can be used to carry out inference in seemingly unrelated regressions or simultaneous equations models with nonparametric components. The approach treats the points on each nonparametric regression line as unknown parameters and uses a prior on the degree of smoothness of each line to ensure valid posterior inference despite the fact that the number of parameters…

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Semiparametric three‐step estimation methods for simultaneous equation systems

联立方程系统的半参数三步估计方法

Abstract This paper proposes a new method for estimating a structural model of labour supply in which hours of work depend on (log) wages and the wage rate is considered endogenous. The main innovation with respect to other related estimation procedures is that a nonparametric additive structure in the hours of work equation is permitted. Though the focus of the paper is on this particular application, a three‐step methodology for estimating models in the presence of the…

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Semiparametric estimation for stationary processes whose spectra have an unknown pole

谱密度具有未知极点的平稳过程半参数估计

We consider the estimation of the location of the pole and memory parameter, λ0 and α, respectively, of covariance stationary linear processes whose spectral density function f(λ) satisfies f(λ)∼C|λ−λ0|−α in a neighborhood of λ0. We define a consistent estimator of λ0 and derive its limit distribution Zλ0. As in related optimization problems, when the true parameter value can lie on the boundary of the parameter space, we show that Zλ0 is distributed as a normal random…

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Efficiency improvements in inference on stationary and nonstationary fractional time series

平稳与非平稳分数阶时间序列推断的效率改进

We consider a time series model involving a fractional stochastic component, whose integration order can lie in the stationary/invertible or nonstationary regions and be unknown, and an additive deterministic component consisting of a generalized polynomial. The model can thus incorporate competing descriptions of trending behavior. The stationary input to the stochastic component has parametric autocorrelation, but innovation with distribution of unknown form. The model is…

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SOME CONVERGENCE THEORY FOR ITERATIVE ESTIMATION PROCEDURES WITH AN APPLICATION TO SEMIPARAMETRIC ESTIMATION

迭代估计程序的收敛理论及其半参数估计应用

We develop general conditions for rates of convergence and convergence in distribution of iterative procedures for estimating finite-dimensional parameters. An asymptotic contraction mapping condition is the centerpiece of the theory. We illustrate some of the results by deriving the limiting distribution of a two-stage iterative estimator of regression parameters in a semiparametric binary response model. Simulation results illustrating the computational benefits of the…

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Estimating Long Memory in Volatility

波动率长记忆的估计

We consider semiparametric estimation of the memory parameter in a model that includes as special cases both long-memory stochastic volatility and fractionally integrated exponential GARCH (FIEGARCH) models. Under our general model the logarithms of the squared returns can be decomposed into the sum of a long-memory signal and a white noise. We consider periodogram-based estimators using a local Whittle criterion function. We allow the optional inclusion of an additional…

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