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An Efficient Estimator for the Generalized Semilinear Model

广义半线性模型的有效估计量

The generalized semilinear model (GSLIM) extends the generalized linear model by allowing the addition of an unknown smooth function to the predictor parameter, producing a semiparametric model. Some previously proposed score-based estimators for the parametric component in this model are not √n consistent. We propose efficient estimators for both the parametric and nonparametric components of the GSLIM. The estimator for the parametric component is the solution to an…

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Penalized quasi-likelihood estimation in partial linear models

部分线性模型中的惩罚准似然估计

Consider a partial linear model, where the expectation of a random variable Y depends on covariates $(x, z)$ through $F(\theta_0 x + m_0(z))$, with $\theta_0$ an unknown parameter, and $m_0$ an unknown function. We apply the theory of empirical processes to derive the asymptotic properties of the penalized quasi-likelihood estimator.

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Interpolation Methods for Adapting to Sparse Design in Nonparametric Regression

非参数回归中适应稀疏设计的插值方法

We suggest interpolation methods for overcoming the problem of sparse design in local linear smoothing. These methods are based on simple rules, determined by the kernel and bandwidth, for deciding when and where pseudo-design points should be added to augment the original design sequence. New ordinates for the added design points are computed by simple interpolation, then local linear smoothing is applied directly to the expanded dataset. The method is competitive with…

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No-Observed-Adverse-Effect Levels in Severity Data

毒性严重程度数据中的未观察到不良反应剂量水平

Toxicity data are often categorized by severity of response and dose level with the assumption that there is a tolerated dose below which there is no toxicity. For data from a controlled experiment, the largest observed dose at or below the tolerated dose is called the no-observed-adverse-effect level (NOAEL). The problem of identifying the NOAEL can be viewed statistically as estimating the maximal observed dose for which there is no increased severity or frequency of toxic…

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Interpolation Methods for Adapting to Sparse Design in Nonparametric Regression: Comment

适应非参数回归稀疏设计的插值方法:评论

We suggest interpolation methods for overcoming the problem of sparse design in local linear smoothing. These methods are based on simple rules, determined by the kernel and bandwidth, for deciding when and where pseudo-design points should be added to augment the original design sequence. New ordinates for the added design points are computed by simple interpolation, then local linear smoothing is applied directly to the expanded dataset. The method is competitive with…

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Interpolation Methods for Adapting to Sparse Design in Nonparametric Regression

非参数回归中适应稀疏设计的插值方法

We suggest interpolation methods for overcoming the problem of sparse design in local linear smoothing. These methods are based on simple rules, determined by the kernel and bandwidth, for deciding when and where pseudo-design points should be added to augment the original design sequence. New ordinates for the added design points are computed by simple interpolation, then local linear smoothing is applied directly to the expanded dataset. The method is competitive with…

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No-Observed-Adverse-Effect Levels in Severity Data

毒性严重程度数据中的无可观察不良效应水平

Toxicity data are often categorized by severity of response and dose level with the assumption that there is a tolerated dose below which there is no toxicity. For data from a controlled experiment, the largest observed dose at or below the tolerated dose is called the no-observed-adverse-effect level (NOAEL). The problem of identifying the NOAEL can be viewed statistically as estimating the maximal observed dose for which there is no increased severity or frequency of toxic…

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Bayesian Model Averaging for Linear Regression Models

线性回归模型的贝叶斯模型平均

We consider the problem of accounting for model uncertainty in linear regression models. Conditioning on a single selected model ignores model uncertainty, and thus leads to the underestimation of uncertainty when making inferences about quantities of interest. A Bayesian solution to this problem involves averaging over all possible models (i.e., combinations of predictors) when making inferences about quantities of interest. This approach is often not practical. In this…

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Maximum Likelihood Algorithms for Generalized Linear Mixed Models

广义线性混合模型的最大似然算法

Maximum likelihood algorithms are described for generalized linear mixed models. I show how to construct a Monte Carlo version of the EM algorithm, propose a Monte Carlo Newton-Raphson algorithm, and evaluate and improve the use of importance sampling ideas. Calculation of the maximum likelihood estimates is feasible for a wide variety of problems where they were not previously. I also use the Newton-Raphson algorithm as a framework to compare maximum likelihood to the…

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Locally adaptive regression splines

局部自适应回归样条

Least squares penalized regression estimates with total variation penalties are considered. It is shown that these estimators are least squares splines with locally data adaptive placed knot points. The definition of these variable knot splines as minimizers of global functionals can be used to study their asymptotic properties. In particular, these results imply that the estimates adapt well to spatially inhomogeneous smoothness. We show rates of convergence in bounded…

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Generalised information criteria in model selection

模型选择中的广义信息准则

The problem of evaluating the goodness of statistical models is investigated from an information-theoretic point of view. Information criteria are proposed for evaluating models constructed by various estimation procedures when the specified family of probability distributions does not contain the distribution generating the data. The proposed criteria are applied to the evaluation of models estimated by maximum likelihood, robust, penalised likelihood, Bayes procedures,…

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Regularized Gaussian Discriminant Analysis through Eigenvalue Decomposition

基于特征值分解的正则化高斯判别分析

Friedman proposed a regularization technique (RDA) of discriminant analysis in the Gaussian framework. RDA uses two regularization parameters to design an intermediate classifier between the linear, the quadratic the nearest-means classifiers. In this article we propose an alternative approach, called EDDA, that is based on the reparameterization of the covariance matrix [Σ k ] of a group Gk in terms of its eigenvalue decomposition Σ k = λ k D k A k D k ′, where λk specifies…

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Combining Estimates in Regression and Classification

回归与分类中的估计组合

We consider the problem of how to combine a collection of general regression fit vectors to obtain a better predictive model. The individual fits may be from subset linear regression, ridge regression, or something more complex like a neural network. We develop a general framework for this problem and examine a cross-validation—based proposal called “model mix” or “stacking” in this context. We also derive combination methods based on the bootstrap and analytic methods and…

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Smoothing Hazard Functions and Time-Varying Effects in Discrete Duration and Competing Risks Models

离散持续期与竞争风险模型中风险率及时变效应的平滑估计

State-space or dynamic approaches to discrete or grouped duration data with competing risks or multiple terminating events allow simultaneous modeling and smooth estimation of hazard functions and time-varying effects in a flexible way. Full Bayesian or posterior mean estimation, using numerical integration techniques or Monte Carlo methods, can become computationally rather demanding or even infeasible for higher dimensions and larger datasets. Therefore, based on previous…

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Smoothing Hazard Functions and Time-Varying Effects in Discrete Duration and Competing Risks Models

离散持续期与竞争风险模型中风险函数和时变效应的平滑

State-space or dynamic approaches to discrete or grouped duration data with competing risks or multiple terminating events allow simultaneous modeling and smooth estimation of hazard functions and time-varying effects in a flexible way. Full Bayesian or posterior mean estimation, using numerical integration techniques or Monte Carlo methods, can become computationally rather demanding or even infeasible for higher dimensions and larger datasets. Therefore, based on previous…

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Continuum Regression is Not Always Continuous

连续统回归并不总是连续

SUMMARY Continuum regression (CR) is regression of a response y on that linear combination t γ of explanatory variables which maximizes r 2(y, t) var(t)γ, where γ is chosen from a continuum of candidates. CR includes several common methods as special cases: ordinary least squares, principal component regression, partial least squares and a modified ridge regression. We demonstrate that CR, despite its name, can yield a predictor that is a discontinuous function of γ and of…

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Bias Correction in Generalized Linear Mixed Models with Multiple Components of Dispersion

多离散度分量广义线性混合模型的偏差校正

General formulas are derived for the asymptotic bias in regression coefficients and variance components estimated by penalized quasi-likelihood (PQL) in generalized linear mixed models with canonical link function and multiple sets of independent random effects. Easily computed correction matrices result in variance component estimates that have satisfactory asymptotic behavior for small values of the variance components and significantly reduce bias for larger values. Both…

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Automatic estimation of the cross-spectrum of a bivariate time series

二元时间序列互谱的自动估计

The penalised Whittle likelihood has recently been shown to have good properties in nonparametric estimation of spectral density functions. This paper extends the approach to the estimation of the cross-spectrum of a bivariate time series. One major difference from the univariate case is that the cross-spectrum estimate is not constrained to be positive, but must result in a positive definite spectral density matrix. An efficient computational method based on iterative…

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Predictive specification of prior model probabilities in variable selection

变量选择中模型先验概率的预测式设定

We examine the problem of specifying prior probabilities for all possible subset models in the context of variable selection in normal linear models. A solution is proposed that uses a prior prediction for the observable, an associated weight, and prior opinion regarding error precision as the only required input. Numerical examples are given to illustrate the method.

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Finite-Sample Variance of Local Polynomials: Analysis and Solutions

局部多项式的有限样本方差:分析与解决方法

Fitting local polynomials in nonparametric regression has a number of advantages. The attractive theoretical features are in a partial contradiction to variance properties for random design and to practical experience over a broad range of situations. No upper bound can be given for the conditional variance. The unconditional variance is infinite when using optimal weights with compact support. Properties are better for Gaussian weights. We analyze local polynomials for…

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Regression Shrinkage and Selection Via the Lasso

通过 Lasso 实现回归收缩与变量选择

SUMMARY We propose a new method for estimation in linear models. The ‘lasso’ minimizes the residual sum of squares subject to the sum of the absolute value of the coefficients being less than a constant. Because of the nature of this constraint it tends to produce some coefficients that are exactly 0 and hence gives interpretable models. Our simulation studies suggest that the lasso enjoys some of the favourable properties of both subset selection and ridge regression. It…

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Variational Solution of Penalized Likelihood Problems and Smooth Curve Estimation

惩罚似然问题的变分解与平滑曲线估计

Usual nonparametric regression estimators often show many little wiggles which do not appear to be necessary for a good description of the data. The new "Wp" smoother is a maximum penalized likelihood (MPL) estimate with a novel roughness penalty. It penalizes a relative change of curvature. This leads to disjoint classes of functions, each with given number, $n_w$, of inflection points. For a "Wp" estimate, $f"(x) = \pm (x - w_1)\cdots (x - w_{n_w}) \cdot \exp h_f(x)$,…

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Nonparametric Transformations for Both Sides of a Regression Model

回归模型两侧的非参数变换

SUMMARY One way to model heteroscedasticity and skewness of the error distribution in regression is to transform both sides of the regression equation. If it is possible to transform the regression equation to result in normally distributed errors, then we can obtain more efficient parameter estimates and valid prediction intervals. One problem with this approach is that the choice of transformation is usually restricted to the power or shifted power family. Often there is…

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