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Anomaly Detection for a Large Number of Streams: A Permutation-Based Higher Criticism Approach

大量数据流的异常检测:基于置换的高批评统计量方法

Anomaly detection when observing a large number of data streams is essential in a variety of applications, ranging from epidemiological studies to monitoring of complex systems. High-dimensional scenarios are usually tackled with scan-statistics and related methods, requiring stringent modeling assumptions for proper calibration. In this work we take a nonparametric stance, and propose a permutation-based variant of the higher criticism statistic not requiring knowledge of…

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Bootstrapping Extreme Value Estimators

极值估计量的自助法

This article develops a bootstrap analogue of the well-known asymptotic expansion of the tail quantile process in extreme value theory. One application of this result is to construct confidence intervals for estimators of the extreme value index such as the Probability Weighted Moment (PWM) estimator. For the peaks-over-threshold method, we show the bootstrap consistency of the confidence intervals. By contrast, the asymptotic expansion of the quantile process of the…

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A Mass-Shifting Phenomenon of Truncated Multivariate Normal Priors

截断多元正态先验的概率质量偏移现象

We show that lower-dimensional marginal densities of dependent zero-mean normal distributions truncated to the positive orthant exhibit a mass-shifting phenomenon. Despite the truncated multivariate normal density having a mode at the origin, the marginal density assigns increasingly small mass near the origin as the dimension increases. The phenomenon accentuates with stronger correlation between the random variables. This surprising behavior has serious implications toward…

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Estimating the Spectral Density at Frequencies Near Zero

零频率附近的谱密度估计

Estimating the spectral density function f(w) for some w∈[−π,π] has been traditionally performed by kernel smoothing the periodogram and related techniques. Kernel smoothing is tantamount to local averaging, that is, approximating f(w) by a constant over a window of small width. Although f(w) is uniformly continuous and periodic with period 2π, in this article we recognize the fact that w = 0 effectively acts as a boundary point in the underlying kernel smoothing problem,…

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Distribution of Distances based Object Matching: Asymptotic Inference

基于距离分布的对象匹配:渐近推断

In this article, we aim to provide a statistical theory for object matching based on a lower bound of the Gromov-Wasserstein distance related to the distribution of (pairwise) distances of the considered objects. To this end, we model general objects as metric measure spaces. Based on this, we propose a simple and efficiently computable asymptotic statistical test for pose invariant object discrimination. This is based on a (β-trimmed) empirical version of the…

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Inference in Heavy-Tailed Nonstationary Multivariate Time Series

重尾非平稳多元时间序列中的推断

We study inference on the common stochastic trends in a non-stationary, $N$-variate time series $y_{t}$, in the possible presence of heavy tails. We propose a novel methodology which does not require any knowledge or estimation of the tail index, or even knowledge as to whether certain moments (such as the variance) exist or not, and develop an estimator of the number of stochastic trends $m$ based on the eigenvalues of the sample second moment matrix of $y_{t}$. We study…

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Fisher-Pitman Permutation Tests Based on Nonparametric Poisson Mixtures with Application to Single Cell Genomics

基于非参数泊松混合的 Fisher–Pitman 置换检验及其单细胞基因组学应用

This article investigates the theoretical and empirical performance of Fisher-Pitman-type permutation tests for assessing the equality of unknown Poisson mixture distributions. Building on nonparametric maximum likelihood estimators (NPMLEs) of the mixing distribution, these tests are theoretically shown to be able to adapt to complicated unspecified structures of count data and also consistent against their corresponding ANOVA-type alternatives; the latter is a result in…

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Fisher’s Combined Probability Test for High-Dimensional Covariance Matrices

高维协方差矩阵的Fisher合并概率检验

Testing large covariance matrices is of fundamental importance in statistical analysis with high-dimensional data. In the past decade, three types of test statistics have been studied in the literature: quadratic form statistics, maximum form statistics, and their weighted combination. It is known that quadratic form statistics would suffer from low power against sparse alternatives and maximum form statistics would suffer from low power against dense alternatives. The…

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Assumption-Lean Cox Regression

弱模型假设下的Cox回归

Inference for the conditional association between an exposure and a time-to-event endpoint, given covariates, is routinely based on partial likelihood estimators for hazard ratios indexing Cox proportional hazards models. This approach is flexible and makes testing straightforward, but is nonetheless not entirely satisfactory. First, there is no good understanding of what it infers when the model is misspecified. Second, it is common to employ variable selection procedures…

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To Adjust or not to Adjust? Estimating the Average Treatment Effect in Randomized Experiments with Missing Covariates

调整还是不调整?协变量缺失时随机实验平均处理效应的估计

Complete randomization allows for consistent estimation of the average treatment effect based on the difference in means of the outcomes without strong modeling assumptions on the outcome-generating process. Appropriate use of the pretreatment covariates can further improve the estimation efficiency. However, missingness in covariates is common in experiments and raises an important question: should we adjust for covariates subject to missingness, and if so, how? The…

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Selective Inference for Hierarchical Clustering

层次聚类的选择后推断

Classical tests for a difference in means control the Type I error rate when the groups are defined a priori. However, when the groups are instead defined via clustering, then applying a classical test yields an extremely inflated Type I error rate. Notably, this problem persists even if two separate and independent datasets are used to define the groups and to test for a difference in their means. To address this problem, in this article, we propose a selective inference…

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Fast and Numerically Stable Particle-Based Online Additive Smoothing: The AdaSmooth Algorithm

快速且数值稳定的粒子在线加性平滑:AdaSmooth 算法

We present a novel sequential Monte Carlo approach to online smoothing of additive functionals in a very general class of path-space models. Hitherto, the solutions proposed in the literature suffer from either long-term numerical instability due to particle-path degeneracy or, in the case that degeneracy is remedied by particle approximation of the so-called backward kernel, high computational demands. In order to balance optimally computational speed against numerical…

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Optimal Nonparametric Inference with Two-Scale Distributional Nearest Neighbors

基于双尺度分布近邻的最优非参数推断

The weighted nearest neighbors (WNN) estimator has been popularly used as a flexible and easy-to-implement nonparametric tool for mean regression estimation. The bagging technique is an elegant way to form WNN estimators with weights automatically generated to the nearest neighbors (Steele, 2009; Biau et al., 2010); we name the resulting estimator as the distributional nearest neighbors (DNN) for easy reference. Yet, there is a lack of distributional results for such…

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Off-Policy Confidence Interval Estimation with Confounded Markov Decision Process

存在混杂的马尔可夫决策过程中的离线策略价值置信区间估计

This article is concerned with constructing a confidence interval for a target policy’s value offline based on a pre-collected observational data in infinite horizon settings. Most of the existing works assume no unmeasured variables exist that confound the observed actions. This assumption, however, is likely to be violated in real applications such as healthcare and technological industries. In this article, we show that with some auxiliary variables that mediate the…

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Scaled Process Priors for Bayesian Nonparametric Estimation of the Unseen Genetic Variation

用于未观测遗传变异估计的贝叶斯非参数缩放过程先验

There is a growing interest in the estimation of the number of unseen features, mostly driven by biological applications. A recent work brought out a peculiar property of the popular completely random measures (CRMs) as prior models in Bayesian nonparametric (BNP) inference for the unseen-features problem: for fixed prior's parameters, they all lead to a Poisson posterior distribution for the number of unseen features, which depends on the sampling information only through…

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An Empirical Bayes Approach to Shrinkage Estimation on the Manifold of Symmetric Positive-Definite Matrices

对称正定矩阵流形上收缩估计的经验贝叶斯方法

The James–Stein estimator is an estimator of the multivariate normal mean and dominates the maximum likelihood estimator (MLE) under squared error loss. The original work inspired great interest in developing shrinkage estimators for a variety of problems. Nonetheless, research on shrinkage estimation for manifold-valued data is scarce. In this article, we propose shrinkage estimators for the parameters of the Log-Normal distribution defined on the manifold of N × N…

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Nearly Dimension-Independent Sparse Linear Bandit over Small Action Spaces via Best Subset Selection

通过最佳子集选择实现小行动空间下近乎维数无关的稀疏线性赌博机

We consider the stochastic contextual bandit problem under the high dimensional linear model. We focus on the case where the action space is finite and random, with each action associated with a randomly generated contextual covariate. This setting finds essential applications such as personalized recommendations, online advertisements, and personalized medicine. However, it is very challenging to balance the exploration and exploitation tradeoff. We modify the LinUCB…

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Hidden Markov Pólya Trees for High-Dimensional Distributions

用于高维分布的隐马尔可夫 Pólya 树

The Pólya tree (PT) process is a general-purpose Bayesian nonparametric model that has found wide application in a range of inference problems. It has a simple analytic form and the posterior computation boils down to beta-binomial conjugate updates along a partition tree over the sample space. Recent development in PT models shows that performance of these models can be substantially improved by (i) allowing the partition tree to adapt to the structure of the underlying…

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Bias-Correction and Test for Mark-Point Dependence with Replicated Marked Point Processes

重复标记点过程中的标记与点依赖:偏差校正及检验

Mark-point dependence plays a critical role in research problems that can be fitted into the general framework of marked point processes. In this work, we focus on adjusting for mark-point dependence when estimating the mean and covariance functions of the mark process, given independent replicates of the marked point process. We assume that the mark process is a Gaussian process and the point process is a log-Gaussian Cox process, where the mark-point dependence is…

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Conformal Sensitivity Analysis for Individual Treatment Effects

个体处理效应的共形敏感性分析

Estimating an individual treatment effect (ITE) is essential to personalized decision making. However, existing methods for estimating the ITE often rely on unconfoundedness, an assumption that is fundamentally untestable with observed data. To assess the robustness of individual-level causal conclusion with unconfoundedness, this paper proposes a method for sensitivity analysis of the ITE, a way to estimate a range of the ITE under unobserved confounding. The method we…

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Low-Rank Regression Models for Multiple Binary Responses and their Applications to Cancer Cell-Line Encyclopedia Data

多重二元响应的低秩回归及其癌症细胞系百科数据应用

In this paper, we study high-dimensional multivariate logistic regression models in which a common set of covariates is used to predict multiple binary outcomes simultaneously. Our work is primarily motivated from many biomedical studies with correlated multiple responses such as the cancer cell-line encyclopedia project. We assume that the underlying regression coefficient matrix is simultaneously low-rank and row-wise sparse. We propose an intuitively appealing selection…

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Bayesian Markov-Switching Tensor Regression for Time-Varying Networks

用于时变网络的贝叶斯马尔可夫切换张量回归

Modeling time series of multilayer network data is challenging due to the peculiar characteristics of real-world networks, such as sparsity and abrupt structural changes. Moreover, the impact of external factors on the network edges is highly heterogeneous due to edge- and time-specific effects. Capturing all these features results in a very high-dimensional inference problem. A novel tensor-on-tensor regression model is proposed, which integrates zero-inflated logistic…

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Randomization-based Joint Central Limit Theorem and Efficient Covariate Adjustment in Randomized Block 2 K Factorial Experiments

随机区组析因实验的随机化联合中心极限定理与高效协变量调整

Randomized block factorial experiments are widely used in industrial engineering, clinical trials, and social science. Researchers often use a linear model and analysis of covariance to analyze experimental results; however, limited studies have addressed the validity and robustness of the resulting inferences because assumptions for a linear model might not be justified by randomization in randomized block factorial experiments. In this article, we establish a new finite…

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A New and Unified Family of Covariate Adaptive Randomization Procedures and Their Properties

统一的协变量自适应随机化程序族及其性质

In clinical trials and other comparative studies, covariate balance is crucial for credible and efficient assessment of treatment effects. Covariate adaptive randomization (CAR) procedures are extensively used to reduce the likelihood of covariate imbalances occurring. In the literature, most studies have focused on balancing of discrete covariates. Applications of CAR with continuous covariates remain rare, especially when the interest goes beyond balancing only the first…

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