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A Unified Nonparametric Fiducial Approach to Interval-Censored Data

区间删失数据的统一非参数 fiducial 推断

Censored data, where the event time is partially observed, are challenging for survival probability estimation. In this article, we introduce a novel nonparametric fiducial approach to interval-censored data, including right-censored, current status, case II censored, and mixed case censored data. The proposed approach leveraging a simple Gibbs sampler has a useful property of being “one size fits all,” that is, the proposed approach automatically adapts to all types of…

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Asymptotic Distribution-Free Independence Test for High-Dimension Data

高维数据的渐近分布无关独立性检验

Test of independence is of fundamental importance in modern data analysis, with broad applications in variable selection, graphical models, and causal inference. When the data is high dimensional and the potential dependence signal is sparse, independence testing becomes very challenging without distributional or structural assumptions. In this paper, we propose a general framework for independence testing by first fitting a classifier that distinguishes the joint and…

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Ideal Bayesian Spatial Adaptation

理想的贝叶斯局部自适应

Many real-life applications involve estimation of curves that exhibit complicated shapes including jumps or varying-frequency oscillations. Practical methods have been devised that can adapt to a locally varying complexity of an unknown function (e.g. variable-knot splines, sparse wavelet reconstructions, kernel methods or trees/forests). However, the overwhelming majority of existing asymptotic minimaxity theory is predicated on homogeneous smoothness assumptions. Focusing…

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A Wasserstein Index of Dependence for Random Measures

随机测度依赖性的 Wasserstein 指数

Optimal transport and Wasserstein distances are flourishing in many scientific fields as a means for comparing and connecting random structures. Here we pioneer the use of an optimal transport distance between Lévy measures to solve a statistical problem. Dependent Bayesian nonparametric models provide flexible inference on distinct, yet related, groups of observations. Each component of a vector of random measures models a group of exchangeable observations, while their…

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Smoothness-Penalized Deconvolution (SPeD) of a Density Estimate

密度估计的平滑惩罚反卷积方法

This article addresses the deconvolution problem of estimating a square-integrable probability density from observations contaminated with additive measurement errors having a known density. The estimator begins with a density estimate of the contaminated observations and minimizes a reconstruction error penalized by an integrated squared mth derivative. Theory for deconvolution has mainly focused on kernel- or wavelet-based techniques, but other methods including…

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Robust Leave-One-Out Cross-Validation for High-Dimensional Bayesian Models

高维贝叶斯模型的稳健留一交叉验证

Leave-one-out cross-validation (LOO-CV) is a popular method for estimating out-of-sample predictive accuracy. However, computing LOO-CV criteria can be computationally expensive due to the need to fit the model multiple times. In the Bayesian context, importance sampling provides a possible solution but classical approaches can easily produce estimators whose asymptotic variance is infinite, making them potentially unreliable. Here we propose and analyze a novel mixture…

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Spatiotemporal Clustering with Neyman-Scott Processes via Connections to Bayesian Nonparametric Mixture Models

通过贝叶斯非参数混合模型联系实现 Neyman–Scott 时空聚类

Neyman-Scott processes (NSPs) are point process models that generate clusters of points in time or space. They are natural models for a wide range of phenomena, ranging from neural spike trains to document streams. The clustering property is achieved via a doubly stochastic formulation: first, a set of latent events is drawn from a Poisson process; then, each latent event generates a set of observed data points according to another Poisson process. This construction is…

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HAC Covariance Matrix Estimation in Quantile Regression

分位数回归中的异方差与自相关稳健协方差矩阵估计

This study considers an estimator for the asymptotic variance-covariance matrix in time-series quantile regression models which is robust to the presence of heteroscedasticity and autocorrelation. When regression errors are serially correlated, the conventional quantile regression standard errors are invalid. The proposed solution is a quantile analogue of the Newey-West robust standard errors. We establish the asymptotic properties of the heteroscedasticity and…

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A Randomized Pairwise Likelihood Method for Complex Statistical Inferences

复杂统计推断的随机化成对似然方法

Pairwise likelihood methods are commonly used for inference in parametric statistical models in cases where the full likelihood is too complex to be used, such as multivariate count data. Although pairwise likelihood methods represent a useful solution to perform inference for intractable likelihoods, several computational challenges remain. The pairwise likelihood function still requires the computation of a sum over all pairs of variables and all observations, which may be…

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Graphical Model Inference with Erosely Measured Data

不规则测量数据下的高斯图模型推断

In this article, we investigate the Gaussian graphical model inference problem in a novel setting that we call erose measurements, referring to irregularly measured or observed data. For graphs, this results in different node pairs having vastly different sample sizes which frequently arises in data integration, genomics, neuroscience, and sensor networks. Existing works characterize the graph selection performance using the minimum pairwise sample size, which provides…

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Generalized Bayesian Inference for Discrete Intractable Likelihood

离散难计算似然的广义贝叶斯推断

Discrete state spaces represent a major computational challenge to statistical inference, since the computation of normalization constants requires summation over large or possibly infinite sets, which can be impractical. This article addresses this computational challenge through the development of a novel generalized Bayesian inference procedure suitable for discrete intractable likelihood. Inspired by recent methodological advances for continuous data, the main idea is to…

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Nonparametric Finite Mixture: Applications in Overcoming Misclassification Bias

非参数有限混合:克服误分类偏误的应用

Investigating the differential effect of treatments in groups defined by patient characteristics is of paramount importance in personalized medicine research. In some studies, participants are first classified as having or not of the characteristic of interest by diagnostic tools, but such classifiers may not be perfectly accurate. The impact of diagnostic misclassification in statistical inference has been recently investigated in parametric model contexts and shown to…

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Semiparametrically Efficient Method for Enveloped Central Space

包络中心子空间的半参数有效估计

The estimation of the central space is at the core of the sufficient dimension reduction (SDR) literature. However, it is well known that the finite-sample estimation suffers from collinearity among predictors. Cook et al. (2013) proposed the predictor envelope method under linear models that can alleviate the problem by targeting a bigger space - which not only envelopes the central information, but also partitions the predictors by finding an uncorrelated set of material…

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Unified Unconditional Regression for Multivariate Quantiles, M-Quantiles, and Expectiles

多元分位数、M分位数与期望分位数的统一无条件回归

In this article, we develop a unified regression approach to model unconditional quantiles, M-quantiles and expectiles of multivariate dependent variables exploiting the multidimensional Huber’s function. To assess the impact of changes in the covariates across the entire unconditional distribution of the responses, we extend the work of Firpo, Fortin, and Lemieux by running a mean regression of the recentered influence function on the explanatory variables. We discuss the…

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Estimation and Inference of Extremal Quantile Treatment Effects for Heavy-Tailed Distributions

重尾分布下极端分位数处理效应的估计与推断

Causal inference for extreme events has many potential applications in fields such as climate science, medicine and economics. We study the extremal quantile treatment effect of a binary treatment on a continuous, heavy-tailed outcome. Existing methods are limited to the case where the quantile of interest is within the range of the observations. For applications in risk assessment, however, the most relevant cases relate to extremal quantiles that go beyond the data range.…

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Unveiling the Unobservable: Causal Inference on Multiple Derived Outcomes

揭示不可观测量:多个衍生结果的因果推断

In many applications, the interest is in treatment effects on random quantities of subjects, where those random quantities are not directly observable but can be estimated based on data from each subject. In this article, we propose a general framework for conducting causal inference in a hierarchical data generation setting. The identifiability of causal parameters of interest is shown under a condition on the biasedness of subject level estimates and an ignorability…

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A Negative Correlation Strategy for Bracketing in Difference-in-Differences

双重差分中构造效应界限的负相关策略

The method of difference-in-differences (DID) is widely used to study the causal effect of policy interventions in observational studies. DID employs a before and after comparison of the treated and control units to remove bias due to time-invariant unmeasured confounders under the parallel trends assumption. Estimates from DID, however, will be biased if the outcomes for the treated and control units evolve differently in the absence of treatment, namely if the parallel…

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Exact Decoding of a Sequentially Markov Coalescent Model in Genetics

遗传学序列马尔可夫溯祖模型的精确解码

In statistical genetics, the sequentially Markov coalescent (SMC) is an important family of models for approximating the distribution of genetic variation data under complex evolutionary models. Methods based on SMC are widely used in genetics and evolutionary biology, with significant applications to genotype phasing and imputation, recombination rate estimation, and inferring population history. SMC allows for likelihood-based inference using hidden Markov models (HMMs),…

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Empirical Likelihood for Network Data

网络数据的经验似然

This article develops a concept of nonparametric likelihood for network data based on network moments, and proposes general inference methods by adapting the theory of jackknife empirical likelihood. Our methodology can be used not only to conduct inference on population network moments and parameters in network formation models, but also to implement goodness-of-fit testing, such as testing block size for stochastic block models. Theoretically we show that the jackknife…

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Inference in High-Dimensional Multivariate Response Regression with Hidden Variables

存在隐变量的高维多响应回归推断

This article studies the inference of the regression coefficient matrix under multivariate response linear regressions in the presence of hidden variables. A novel procedure for constructing confidence intervals of entries of the coefficient matrix is proposed. Our method first uses the multivariate nature of the responses by estimating and adjusting the hidden effect to construct an initial estimator of the coefficient matrix. By further deploying a low-dimensional…

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De-confounding Causal Inference Using Latent Multiple-Mediator Pathways

利用潜在多中介路径消除因果推断中的混杂

Causal effect estimation from observational data is one of the essential problems in causal inference. However, most estimation methods rely on the strong assumption that all confounders are observed, which is impractical and untestable in the real world. We develop a mediation analysis framework inferring the latent confounder for debiasing both direct and indirect causal effects. Specifically, we introduce generalized structural equation modeling that incorporates…

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Sensitivity to Unobserved Confounding in Studies with Factor-Structured Outcomes

因子结构结果研究中对未观测混杂的敏感性分析

In this work, we propose an approach for assessing sensitivity to unobserved confounding in studies with multiple outcomes. We demonstrate how prior knowledge unique to the multi-outcome setting can be leveraged to strengthen causal conclusions beyond what can be achieved from analyzing individual outcomes in isolation. We argue that it is often reasonable to make a shared confounding assumption, under which residual dependence amongst outcomes can be used to simplify and…

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A Ridge-Regularized Jackknifed Anderson-Rubin Test

岭正则化的刀切 Anderson–Rubin 检验

We consider hypothesis testing in instrumental variable regression models with few included exogenous covariates but many instruments-possibly more than the number of observations. We show that a ridge-regularized version of the jackknifed Anderson and Rubin (henceforth AR) test controls asymptotic size in the presence of heteroscedasticity, and when the instruments may be arbitrarily weak. Asymptotic size control is established under weaker assumptions than those imposed…

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Variational Inference for Large Bayesian Vector Autoregressions

大型贝叶斯向量自回归的变分推断

We propose a novel variational Bayes approach to estimate high-dimensional Vector Autoregressive (VAR) models with hierarchical shrinkage priors.Our approach does not rely on a conventional structural representation of the parameter space for posterior inference.Instead, we elicit hierarchical shrinkage priors directly on the matrix of regression coefficients so that (a) the prior structure maps into posterior inference on the reduced-form transition matrix and (b) posterior…

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