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最大稳定过程的似然推断AI 解读

The last decade has seen max-stable processes emerge as a common tool for the statistical modeling of spatial extremes. However, their application is complicated due to the unavailability of the multivariate density function, and so likelihood-based methods remain far from providing a complete and flexible framework for inference. In this article we develop inferentially practical, likelihood-based methods for fitting max-stable processes derived from a composite-likelihood…

状态空间模型的近似方法AI 解读

State-space models provide an important body of techniques for analyzing time-series, but their use requires estimating unobserved states. The optimal estimate of the state is its conditional expectation given the observation histories, and computing this expectation is hard when there are nonlinearities. Existing filtering methods, including sequential Monte Carlo, tend to be either inaccurate or slow. In this paper, we study a nonlinear filter for nonlinear/non-Gaussian…

使用工具变量的边际与嵌套结构模型AI 解读

The objective of many scientific studies is to evaluate the effect of a treatment on an outcome of interest ceteris paribus. Instrumental variables (IVs) serve as an experimental handle, independent of potential outcomes and potential treatment status and affecting potential outcomes only through potential treatment status. We propose marginal and nested structural models using IVs, in the spirit of marginal and nested structural models under no unmeasured confounding. A…

大规模离散选择模型的变分推断AI 解读

Discrete choice models are commonly used by applied statisticians in numerous fields, such as marketing, economics, finance, and operations research. When agents in discrete choice models are assumed to have differing preferences, exact inference is often intractable. Markov chain Monte Carlo techniques make approximate inference possible, but the computational cost is prohibitive on the large datasets now becoming routinely available. Variational methods provide a…

不可忽略无应答与抽样选择下小域 BMI 数据的贝叶斯分析AI 解读

Here we analyze body mass index (BMI) data for children and adolescents from the Third National Health and Nutrition Examination Survey (NHANES III). Because of the lack of BMI values for a considerable number of the children and adolescents, and the differential probabilities of selection of these individuals, serious nonresponse and selection bias in inference can be present. To analyze the NHANES III BMI data, a nonignorable nonresponse model has been proposed to estimate…

大肠杆菌 SecYEG 孔道的单通道与多通道电流：含噪观测的模态数检验AI 解读

We analyze a new dataset from an electrophysiological recording of transmembrane currents through a bacterial membrane channel to demonstrate the existence of single and multiple channel currents. Protein channels mediate transport through biological membranes; knowledge of the channel properties gained from electrophysiological recordings is important for a targeted drug design. We investigate the bacterial membrane protein SecYEG which is of essential importance for the…

分析纵向数据的广义经验似然方法AI 解读

Abstract Efficient estimation of parameters is a major objective in analyzing longitudinal data. We propose two generalized empirical likelihood-based methods that take into consideration within-subject correlations. A nonparametric version of the Wilks theorem for the limiting distributions of the empirical likelihood ratios is derived. It is shown that one of the proposed methods is locally efficient among a class of within-subject variance-covariance matrices. A…

检验周期性的全局与局部谱方法AI 解读

We investigate tests for periodicity based on a spectral analysis of a time series, differentiating between global and local spectral-based tests. Global tests use information across the entire frequency band,whereas local tests are based on a window around the test frequency.We show that many spectral-based tests can be expressed in terms of a regression-based F test, which allows for approximate size and power calculations. Since global tests are usually derived assuming…

病例对照与队列研究中因果效应的锐界AI 解读

Evaluating the causal effect of an exposure on a response from case-control and cohort studies is a major concern in epidemiological and medical research. Since causal effects are in general nonidentifiable from such studies, this paper derives bounds on two causal measures: the causal risk difference and the causal risk ratio. We use the potential response approach and a linear programming method to derive sharp bounds on the causal risk difference, and a novel fractional…

医疗费用研究中反变换条件均值的估计AI 解读

We propose a new approach for analyzing skewed and heteroscedastic health care cost data through regression of the conditional quantiles of the transformed cost. Using the appealing equivariance property of quantiles to monotone transformations, we propose a distribution-free estimator of the conditional mean cost on the original scale. The proposed method is extended to a two-part heteroscedastic model to account for zero costs commonly seen in health care cost studies.…

利用随机序检验聚类二元数据的趋势AI 解读

We introduce the use of stochastic ordering for defining treatment-related trend in clustered exchangeable binary data for both when cluster sizes are fixed and when they vary randomly. In the latter case, there is a well-documented tendency for such data to be sparse, a problem we address by making an assumption of interpretability or, equivalently, marginal compatibility. Our procedures are based on a representation of the joint distribution of binary exchangeable random…

函数型二次回归AI 解读

We extend the common linear functional regression model to the case where the dependency of a scalar response on a functional predictor is of polynomial rather than linear nature. Focusing on the quadratic case, we demonstrate the usefulness of the polynomial functional regression model, which encompasses linear functional regression as a special case. Our approach works under mild conditions for the case of densely spaced observations and also can be extended to the…

离散统计模型参数的伪得分置信区间AI 解读

We propose pseudo-score confidence intervals for parameters in models for discrete data. The confidence interval is obtained by inverting a test that uses a Pearson chi-squared statistic to compare fitted values for the working model with fitted values of the model when a parameter of interest takes various fixed values. For multinomial models, the pseudo-score method simplifies to the score method when the model is saturated and otherwise it is asymptotically equivalent to…

抽样位置存在误差时的系统抽样AI 解读

Systematic sampling of points in continuous space is widely used in microscopy and spatial surveys. Classical theory provides asymptotic expressions for the variance of estimators based on systematic sampling as the grid spacing decreases. However, the classical theory assumes that the sample grid is exactly periodic; real physical sampling procedures may introduce errors in the placement of the sample points. This paper studies the effect of errors in sample positioning on…

随机场谱密度函数的非参数贝叶斯推断AI 解读

A powerful technique for inference concerning spatial dependence in a random field is to use spectral methods based on frequency domain analysis. Here we develop a nonparametric Bayesian approach to statistical inference for the spectral density of a random field. We construct a multi-dimensional Bernstein polynomial prior for the spectral density and devise a Markov chain Monte Carlo algorithm to simulate from the posterior of the spectral density. The posterior sampling…

半参数优势比模型中的双重稳健估计AI 解读

We consider the doubly robust estimation of the parameters in a semiparametric conditional odds ratio model. Our estimators are consistent and asymptotically normal in a union model that assumes either of two variation independent baseline functions is correctly modelled but not necessarily both. Furthermore, when either outcome has finite support, our estimators are semiparametric efficient in the union model at the intersection submodel where both nuisance functions models…

利用虚拟观测在离散剂量水平上进行随机逼近寻量AI 解读

Phase I clinical studies are experiments in which a new drug is administered to humans to determine the maximum dose that causes toxicity with a target probability. Phase I dose-finding is often formulated as a quantile estimation problem. For studies with a biological endpoint, it is common to define toxicity by dichotomizing the continuous biomarker expression. In this article, we propose a novel variant of the Robbins-Monro stochastic approximation that utilizes the…

非参数贝叶斯分析中的最小信息先验分布AI 解读

Summary We address the problem of how to conduct a minimally informative, non-parametric Bayesian analysis. The central question is how to devise a model so that the posterior distribution satisfies a few basic properties. The concept of ‘local mass’ provides the key to the development of the limiting Dirichlet process model. This model is then used to provide an engine for inference in the compound decision problem and for multiple-comparisons inference in a one-way…

统计等价模型下的似然推断AI 解读

Summary In likelihood inference we usually assume that the model is fixed and then base inference on the corresponding likelihood function. Often, however, the choice of model is rather arbitrary, and there may be other models which fit the data equally well. We study robustness of likelihood inference over such ‘statistically equivalent’ models and suggest a simple ‘envelope likelihood’ to capture this aspect of model uncertainty. Robustness depends critically on how we…

非局部先验密度在贝叶斯假设检验中的应用AI 解读

Summary We examine philosophical problems and sampling deficiencies that are associated with current Bayesian hypothesis testing methodology, paying particular attention to objective Bayes methodology. Because the prior densities that are used to define alternative hypotheses in many Bayesian tests assign non-negligible probability to regions of the parameter space that are consistent with null hypotheses, resulting tests provide exponential accumulation of evidence in…

分布性政策效应的非参数估计AI 解读

This paper proposes a fully nonparametric procedure to evaluate the effect of a counterfactual change in the distribution of some covariates on the unconditional distribution of an outcome variable of interest. In contrast to other methods, we do not restrict attention to the effect on the mean. In particular, our method can be used to conduct inference on the change of the distribution function as a whole, its moments and quantiles, inequality measures such as the Lorenz…

异质性面板中的微观与宏观协整AI 解读

We consider the issue of cross-sectional aggregation in nonstationary and heterogeneous panels where each unit cointegrates. We derive asymptotic properties of the aggregate estimate, and necessary and sufficient conditions for cointegration to hold in the aggregate relationship. We then analyze the case when cointegration does not carry through the aggregation process, and we investigate whether the violation of the formal conditions for perfect aggregation can still lead…

利用高频波动率信息预测：HEAVY 模型AI 解读

Abstract This paper studies in some detail a class of high‐frequency‐based volatility (HEAVY) models. These models are direct models of daily asset return volatility based on realised measures constructed from high‐frequency data. Our analysis identifies that the models have momentum and mean reversion effects, and that they adjust quickly to structural breaks in the level of the volatility process. We study how to estimate the models and how they perform through the credit…

多元残差的有限样本序列相关与 ARCH 检验：资产定价应用AI 解读

Abstract In this paper, we propose several finite‐sample specification tests for multivariate linear regressions (MLR). We focus on tests for serial dependence and ARCH effects with possibly non‐Gaussian errors. The tests are based on properly standardized multivariate residuals to ensure invariance to error covariances. The procedures proposed provide: (i) exact variants of standard multivariate portmanteau tests for serial correlation as well as ARCH effects, and (ii)…