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利用复杂抽样数据构建一致的回归树AI 解读

In the past several years a wide range of methods for the construction of regression trees and other estimators based on the recursive partitioning of samples have appeared in the statistics literature. Many applications involve data collected through a complex sample design. At present, however, relatively little is known regarding the properties of these methods under complex designs. This article proposes a method for incorporating information about the complex sample…

长度偏倚数据的最大似然估计与 EM 算法AI 解读

Length-biased sampling has been well recognized in economics, industrial reliability, etiology applications, epidemiological, genetic and cancer screening studies. Length-biased right-censored data have a unique data structure different from traditional survival data. The nonparametric and semiparametric estimations and inference methods for traditional survival data are not directly applicable for length-biased right-censored data. We propose new expectation-maximization…

纵向研究中变化速率函数的半参数随机建模AI 解读

In longitudinal biomedical studies, there is often interest in the rate functions, which describe the functional rates of change of biomarker profiles. This paper proposes a semiparametric approach to model these functions as the realizations of stochastic processes defined by stochastic differential equations. These processes are dependent on the covariates of interest and vary around a specified parametric function. An efficient Markov chain Monte Carlo algorithm is…

用于蛋白质组通路分析的正则化 Hotelling T² 检验AI 解读

Recent proteomic studies have identified proteins related to specific phenotypes. In addition to marginal association analysis for individual proteins, analyzing pathways (functionally related sets of proteins) may yield additional valuable insights. Identifying pathways that differ between phenotypes can be conceptualized as a multivariate hypothesis testing problem: whether the mean vector μ of a p-dimensional random vector X is μ0. Proteins within the same biological…

大规模相关性筛选AI 解读

This article addresses the problem of screening for variables with high correlations in high-dimensional data in which there can be many fewer samples than variables. We focus on threshold-based correlation screening methods for three related applications: screening for variables with large correlations within a single treatment (autocorrelation screening), screening for variables with large cross-correlations over two treatments (cross-correlation screening), and screening…

多变量时间序列的动态正交成分AI 解读

We introduce dynamic orthogonal components (DOC) for multivariate time series and propose a procedure for estimating and testing the existence of DOCs for a given time series. We estimate the dynamic orthogonal components via a generalized decorrelation method that minimizes the linear and quadratic dependence across components and across time. We then use Ljung–Box type statistics to test the existence of dynamic orthogonal components. When DOCs exist, univariate analysis…

随机效应分位数回归模型的半参数方法AI 解读

We consider a random effects quantile regression analysis of clustered data and propose a semiparametric approach using empirical likelihood. The random regression coefficients are assumed independent with a common mean, following parametrically specified distributions. The common mean corresponds to the population-average effects of explanatory variables on the conditional quantile of interest, while the random coefficients represent cluster specific deviations in the…

积分波动率的预测推断AI 解读

Numerous volatility-based derivative products have been engineered in recent years. This has led to interest in constructing conditional predictive densities and confidence intervals for integrated volatility. In this article we propose nonparametric estimators of the aforementioned quantities, based on model-free volatility estimators. We establish consistency and asymptotic normality for the feasible estimators and study their finite-sample properties through a Monte Carlo…

耦合可选 Pólya 树与两样本问题AI 解读

Testing and characterizing the difference between two data samples is of fundamental interest in statistics. Existing methods such as Kolmogorov–Smirnov and Cramer–von Mises tests do not scale well as the dimensionality increases and provide no easy way to characterize the difference should it exist. In this work, we propose a theoretical framework for inference that addresses these challenges in the form of a prior for Bayesian nonparametric analysis. The new prior is…

离散指数族的不稳定性、敏感性与退化AI 解读

In applications to dependent data, first and foremost relational data, a number of discrete exponential family models has turned out to be near-degenerate and problematic in terms of Markov chain Monte Carlo simulation and statistical inference. We introduce the notion of instability with an eye to characterize, detect, and penalize discrete exponential family models that are near-degenerate and problematic in terms of Markov chain Monte Carlo simulation and statistical…

多元二元数据的序约束推断及其毒理学应用AI 解读

In many applications researchers collect multivariate binary response data under two or more, naturally ordered, experimental conditions. In such situations one is often interested in using all binary outcomes simultaneously to detect an ordering among the experimental conditions. To make such comparisons we develop a general methodology for testing for the multivariate stochastic order between K ≥ 2 multivariate binary distributions. The proposed test uses order restricted…

因果推断中连续中间变量的贝叶斯半参数建模AI 解读

In causal inference studies, treatment comparisons often need to be adjusted for confounded post-treatment variables. Principal stratification (PS) is a framework to deal with such variables within the potential outcome approach to causal inference. Continuous intermediate variables introduce inferential challenges to PS analysis. Existing methods either dichotomize the intermediate variable, or assume a fully parametric model for the joint distribution of the potential…

采用正交象限正态先验的弹性网回归建模AI 解读

The elastic net procedure is a form of regularized optimization for linear regression that provides a bridge between ridge regression and the lasso. The estimate that it produces can be viewed as a Bayesian posterior mode under a prior distribution implied by the form of the elastic net penalty. This article broadens the scope of the Bayesian connection by providing a complete characterization of a class of prior distributions that generate the elastic net estimate as the…

多区域采样及其在贝叶斯网络结构推断中的应用AI 解读

When a posterior distribution has multiple modes, unconditional expectations, such as the posterior mean, may not offer informative summaries of the distribution. Motivated by this problem, we propose to decompose the sample space of a multimodal distribution into domains of attraction of local modes. Domain-based representations are defined to summarize the probability masses of and conditional expectations on domains of attraction, which are much more informative than the…

正则化回归估计推断的扰动方法AI 解读

Analysis of high dimensional data often seeks to identify a subset of important features and assess their effects on the outcome. Traditional statistical inference procedures based on standard regression methods often fail in the presence of high-dimensional features. In recent years, regularization methods have emerged as promising tools for analyzing high dimensional data. These methods simultaneously select important features and provide stable estimation of their…

基于似然比检验的信号检测及其 FDA 药物安全数据应用AI 解读

Several statistical methods that are available in the literature to analyze postmarket safety databases, such as the U.S. Federal Drug Administration’s (FDA) adverse event reporting system (AERS), for identifying drug-event combinations with disproportionately high frequencies, are subject to high false discovery rates. Here, we propose a likelihood ratio test (LRT) based method and show, via an extensive simulation study, that the proposed method while retaining good power…

结合混合效应建模的高维常微分方程动态基因调控网络识别AI 解读

Gene regulation is a complicated process. The interaction of many genes and their products forms an intricate biological network. Identification of this dynamic network will help us understand the biological process in a systematic way. However, the construction of such a dynamic network is very challenging for a high-dimensional system. In this article we propose to use a set of ordinary differential equations (ODE), coupled with dimensional reduction by clustering and…

矩条件模型的广义经验似然准则AI 解读

GEL methods that generalize and extend previous contributions are defined and analyzed for moment condition models specified in terms of weakly dependent data. These procedures offer alternative one-step estimators and tests that are asymptotically equivalent to their efficient two-step GMM counterparts. The basis for GEL estimation is via a smoothed version of the moment indicators using kernel function weights that incorporate a bandwidth parameter. Examples for the choice…

等权空间依赖的不可检验性AI 解读

We show that any invariant test for spatial autocorrelation in a spatial error or spatial lag model with equal weights matrix has power equal to size. This result holds under the assumption of an elliptical distribution. Under Gaussianity, we also show that any test whose power is larger than its size for at least one point in the parameter space must be biased.

非线性 AR–GARCH 模型的参数估计AI 解读

This paper develops an asymptotic estimation theory for nonlinear autoregressive models with conditionally heteroskedastic errors. We consider a general nonlinear autoregression of order p (AR( p )) with the conditional variance specified as a general nonlinear first-order generalized autoregressive conditional heteroskedasticity (GARCH(1,1)) model. We do not require the rescaled errors to be independent, but instead only to form a stationary and ergodic martingale…

幂核异方差与自相关稳健检验的检验力最大化和尺寸控制AI 解读

Using the power kernels of Phillips, Sun, and Jin (2006, 2007), we examine the large sample asymptotic properties of the t -test for different choices of power parameter ( ρ ). We show that the nonstandard fixed- ρ limit distributions of the t -statistic provide more accurate approximations to the finite sample distributions than the conventional large- ρ limit distribution. We prove that the second-order corrected critical value based on an asymptotic expansion of the…

平稳与单位根自回归中的一致渐近正态性AI 解读

While differencing transformations can eliminate nonstationarity, they typically reduce signal strength and correspondingly reduce rates of convergence in unit root autoregressions. The present paper shows that aggregating moment conditions that are formulated in differences provides an orderly mechanism for preserving information and signal strength in autoregressions with some very desirable properties. In first order autoregression, a partially aggregated estimator based…

摘要暂缺

过拟合混合模型中后验分布的渐近行为AI 解读

Summary We study the asymptotic behaviour of the posterior distribution in a mixture model when the number of components in the mixture is larger than the true number of components: a situation which is commonly referred to as an overfitted mixture. We prove in particular that quite generally the posterior distribution has a stable and interesting behaviour, since it tends to empty the extra components. This stability is achieved under some restriction on the prior, which…