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Active sequential hypothesis testing

主动序贯假设检验

Consider a decision maker who is responsible to dynamically collect observations so as to enhance his information about an underlying phenomena of interest in a speedy manner while accounting for the penalty of wrong declaration. Due to the sequential nature of the problem, the decision maker relies on his current information state to adaptively select the most “informative” sensing action among the available ones. In this paper, using results in dynamic programming, lower…

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Gaussian approximations and multiplier bootstrap for maxima of sums of high-dimensional random vectors

高维随机向量和最大值的高斯近似与乘子自助法

We derive a Gaussian approximation result for the maximum of a sum of high-dimensional random vectors. Specifically, we establish conditions under which the distribution of the maximum is approximated by that of the maximum of a sum of the Gaussian random vectors with the same covariance matrices as the original vectors. This result applies when the dimension of random vectors ($p$) is large compared to the sample size ($n$); in fact, $p$ can be much larger than $n$, without…

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Sequential estimation of shape parameters in multivariate dynamic models

多元动态模型中分布形状参数的序贯估计

Sequential maximum likelihood and GMM estimators of distributional parameters obtained from the standardised innovations of multivariate conditionally heteroskedastic dynamic regression models evaluated at Gaussian PML estimators preserve the consistency of mean and variance parameters while allowing for realistic distributions. We assess their efficiency, and obtain moment conditions leading to sequential estimators as efficient as their joint ML counterparts. We also…

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Predictive regression under various degrees of persistence and robust long-horizon regression

不同持久性程度下的预测回归与稳健长跨度回归

The paper proposes a novel inference procedure for long-horizon predictive regression with persistent regressors, allowing the autoregressive roots to lie in a wide vicinity of unity. The invalidity of conventional tests when regressors are persistent has led to a large literature dealing with inference in predictive regressions with local to unity regressors. Magdalinos and Phillips (2009b) recently developed a new framework of extended IV procedures (IVX) that enables…

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Testing for unit roots in the possible presence of multiple trend breaks using minimum Dickey–Fuller statistics

利用最小 Dickey–Fuller 统计量检验可能含多重趋势断点的单位根

Trend breaks appear to be prevalent in macroeconomic time series, and unit root tests therefore need to make allowance for these if they are to avoid the serious effects that unmodelled trend breaks have on power. Carrion-i-Silvestre et al. (2009) propose a pre-test-based approach which delivers near asymptotically efficient unit root inference both when breaks do not occur and where multiple breaks occur, provided the break magnitudes are fixed. Unfortunately, however, the…

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Forecasting by factors, by variables, by both or neither?

用因子、变量、二者还是都不用来预测?

We consider forecasting with factors, variables and both, modeling in-sample using Autometrics so all principal components and variables can be included jointly, while tackling multiple breaks by impulse-indicator saturation. A forecast-error taxonomy for factor models highlights the impacts of location shifts on forecast-error biases. Forecasting US GDP over 1-, 4- and 8-step horizons using the dataset from Stock and Watson (2009) updated to 2011:2 shows factor models are…

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Consistent factor estimation in dynamic factor models with structural instability

结构不稳定下动态因子模型的一致因子估计

This paper considers the estimation of approximate dynamic factor models when there is temporal instability in the factor loadings. We characterize the type and magnitude of instabilities under which the principal components estimator of the factors is consistent and find that these instabilities can be larger than earlier theoretical calculations suggest. We also discuss implications of our results for the robustness of regressions based on the estimated factors and of…

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Conditional predictive density evaluation in the presence of instabilities

存在不稳定性时的条件预测密度评价

We propose new methods for evaluating predictive densities. The methods include Kolmogorov–Smirnov and Cramér–von Mises-type tests for the correct specification of predictive densities robust to dynamic mis-specification. The novelty is that the tests can detect mis-specification in the predictive densities even if it appears only over a fraction of the sample, due to the presence of instabilities. Our results indicate that our tests are well sized and have good power in…

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Adaptive forecasting in the presence of recent and ongoing structural change

近期及持续结构变化下的自适应预测

We consider time series forecasting in the presence of ongoing structural change where both the time series dependence and the nature of the structural change are unknown. Methods that downweight older data, such as rolling regressions, forecast averaging over different windows and exponentially weighted moving averages, known to be robust to historical structural change, are found also to be useful in the presence of ongoing structural change in the forecast period. A…

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Optimal forecasts in the presence of structural breaks

存在结构突变时的最优预测

This paper considers the problem of forecasting under continuous and discrete structural breaks and proposes weighting observations to obtain optimal forecasts in the MSFE sense. We derive optimal weights for one step ahead forecasts. Under continuous breaks, our approach largely recovers exponential smoothing weights. Under discrete breaks, we provide analytical expressions for optimal weights in models with a single regressor, and asymptotically valid weights for models…

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A Marginal Approach to Reduced-Rank Penalized Spline Smoothing With Application to Multilevel Functional Data

降秩惩罚样条平滑的边际方法及其多层函数数据应用

Multilevel functional data is collected in many biomedical studies. For example, in a study of the effect of Nimodipine on patients with subarachnoid hemorrhage (SAH), patients underwent multiple 4-hour treatment cycles. Within each treatment cycle, subjects' vital signs were reported every 10 minutes. This data has a natural multilevel structure with treatment cycles nested within subjects and measurements nested within cycles. Most literature on nonparametric analysis of…

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Resampling Procedures for Making Inference Under Nested Case–Control Studies

嵌套病例对照研究中的推断重抽样程序

The nested case-control (NCC) design have been widely adopted as a cost-effective solution in many large cohort studies for risk assessment with expensive markers, such as the emerging biologic and genetic markers. To analyze data from NCC studies, conditional logistic regression (Goldstein and Langholz, 1992; Borgan et al., 1995) and maximum likelihood (Scheike and Juul, 2004; Zeng et al., 2006) based methods have been proposed. However, most of these methods either cannot…

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A Progressive Block Empirical Likelihood Method for Time Series

时间序列的渐进分块经验似然方法

This article develops a new blockwise empirical likelihood (BEL) method for stationary, weakly dependent time processes, called the progressive block empirical likelihood (PBEL). In contrast to the standard version of BEL, which uses data blocks of constant length for a given sample size and whose performance can depend crucially on the block length selection, this new approach involves a data-blocking scheme where blocks increase in length by an arithmetic progression.…

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Locally Adaptive Bayes Nonparametric Regression via Nested Gaussian Processes

通过嵌套高斯过程实现局部自适应贝叶斯非参数回归

We propose a nested Gaussian process (nGP) as a locally adaptive prior for Bayesian nonparametric regression. Specified through a set of stochastic differential equations (SDEs), the nGP imposes a Gaussian process prior for the function’s mth-order derivative. The nesting comes in through including a local instantaneous mean function, which is drawn from another Gaussian process inducing adaptivity to locally varying smoothness. We discuss the support of the nGP prior in…

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Adaptive Testing of Conditional Association Through Recursive Mixture Modeling

通过递归混合建模进行条件关联的自适应检验

In many case-control studies, a central goal is to test for association or dependence between the predictors and the response. Relevant covariates must be conditioned on to avoid false positives and loss in power. Conditioning on covariates is easy in parametric frameworks such as the logistic regression—by incorporating the covariates into the model as additional variables. In contrast, nonparametric methods such as the Cochran-Mantel-Haenszel test accomplish conditioning…

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Generalized Residuals for General Models for Contingency Tables With Application to Item Response Theory

一般列联表模型的广义残差及其项目反应理论应用

Generalized residuals are a tool employed in the analysis of contingency tables to examine possible sources of model error. They have typically been applied to log-linear models and to latent-class models. A general approach to generalized residuals is developed for a very general class of models for contingency tables. To illustrate their use, generalized residuals are applied to models based on item response theory (IRT) models. Such models are commonly applied to analysis…

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Epistatic Clustering: A Model-Based Approach for Identifying Links Between Clusters

上位作用聚类:识别簇间联系的模型方法

Most clustering methods assume that the data can be represented by mutually exclusive clusters, although this assumption may not be the case in practice. For example, in gene expression microarray studies, investigators have often found that a gene can play multiple functions in a cell and may, therefore, belong to more than one cluster simultaneously, and that gene clusters can be linked to each other in certain pathways. This article examines the effect of the above…

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Multiple Testing in a Two-Stage Adaptive Design With Combination Tests Controlling FDR

控制错误发现率的两阶段自适应多重检验与组合检验

Testing multiple null hypotheses in two stages to decide which of these can be rejected or accepted at the first stage and which should be followed up for further testing having had additional observations is of importance in many scientific studies. We develop two procedures, each with two different combination functions, Fisher's and Simes’, to combine p-values from two stages, given prespecified boundaries on the first-stage p-values in terms of the false discovery rate…

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Two-Stage Importance Sampling With Mixture Proposals

采用混合提议分布的两阶段重要性抽样

For importance sampling (IS), multiple proposals can be combined to address different aspects of a target distribution. There are various methods for IS with multiple proposals, including Hesterberg's stratified IS estimator, Owen and Zhou's regression estimator, and Tan's maximum likelihood estimator. For the problem of efficiently allocating samples to different proposals, it is natural to use a pilot sample to select the mixture proportions before the actual sampling and…

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Semiparametric Bayesian Estimation for Marginal Parametric Potential Outcome Modeling: Application to Causal Inference

边际参数化潜在结果模型的半参数贝叶斯因果估计

We propose a new semiparametric Bayesian model for causal inference in which assignment to treatment depends on potential outcomes. The model uses the probit stick-breaking process mixture proposed by Chung and Dunson (Citation2009), a variant of the Dirichlet process mixture modeling. In contrast to previous Bayesian models, the proposed model directly estimates the parameters of the marginal parametric model of potential outcomes, while it relaxes the strong ignorability…

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Local Linear Regression on Manifolds and Its Geometric Interpretation

流形上的局部线性回归及其几何解释

High-dimensional data analysis has been an active area, and the main focus areas have been variable selection and dimension reduction. In practice, it occurs often that the variables are located on an unknown, lower-dimensional nonlinear manifold. Under this manifold assumption, one purpose of this article is regression and gradient estimation on the manifold, and another is developing a new tool for manifold learning. As regards the first aim, we suggest directly reducing…

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Bayesian Inference for Logistic Models Using Pólya–Gamma Latent Variables

利用 Pólya–Gamma 潜变量进行逻辑模型贝叶斯推断

We propose a new data-augmentation strategy for fully Bayesian inference in models with binomial likelihoods. The approach appeals to a new class of Pólya–Gamma distributions, which are constructed in detail. A variety of examples are presented to show the versatility of the method, including logistic regression, negative binomial regression, nonlinear mixed-effect models, and spatial models for count data. In each case, our data-augmentation strategy leads to simple,…

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Classification Using Censored Functional Data

利用删失函数型数据进行分类

We consider classification of functional data when the training curves are not observed on the same interval. Different types of classifier are suggested, one of which involves a new curve extension procedure. Our approach enables us to exploit the information contained in the endpoints of these intervals by incorporating it in an explicit but flexible way. We study asymptotic properties of our classifiers, and show that, in a variety of settings, they can even produce…

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Case Definition and Design Sensitivity

病例定义与设计敏感度

In a case-referent study, cases of disease are compared to non-cases with respect to their antecedent exposure to a treatment in an effort to determine whether exposure causes some cases of the disease. Because exposure is not randomly assigned in the population, as it would be if the population were a vast randomized trial, exposed and unexposed subjects may differ prior to exposure with respect to covariates that may or may not have been measured. After controlling for…

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