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《随机对象理论：概率、随机过程与推断》AI 解读

The task of writing a novel textbook on general probability theory seems virtually impossible nowadays. In Theory of Stochastic Objects, the author Athanasios Micheas aims to overcome this challeng...

组学与成像大数据：整合分析与因果推断AI 解读

Despite our expanding knowledge, we are still very ignorant about many parts of the function and functioning of the human brain and the genes. The challenges and ignorance are equally large for sta...

分布型数据的分位数函数对标量回归分析AI 解读

Radiomics involves the study of tumor images to identify quantitative markers explaining cancer heterogeneity. The predominant approach is to extract hundreds to thousands of image features, including histogram features comprised of summaries of the marginal distribution of pixel intensities, which leads to multiple testing problems and can miss out on insights not contained in the selected features. In this paper, we present methods to model the entire marginal distribution…

离散结果的分位数函数与分位数效应函数的一般推断AI 解读

Quantile and quantile effect functions are important tools for descriptive and causal analyses due to their natural and intuitive interpretation. Existing inference methods for these functions do not apply to discrete random variables. This paper offers a simple, practical construction of simultaneous confidence bands for quantile and quantile effect functions of possibly discrete random variables. It is based on a natural transformation of simultaneous confidence bands for…

患者预警系统中缺失数据下的预测与推断AI 解读

We describe the Bedside Patient Rescue (BPR) project, the goal of which is risk prediction of adverse events for non-intensive care unit patients using ∼100 variables (vitals, lab results, assessments, etc.). There are several missing predictor values for most patients, which in the health sciences is the norm, rather than the exception. A Bayesian approach is presented that addresses many of the shortcomings to standard approaches to missing predictors: (i) treatment of the…

具有随机分组的需求模型AI 解读

Many economic models of consumer demand require researchers to partition sets of products or attributes prior to the analysis. These models are common in applied problems when the product space is large or spans multiple categories. While the partition is traditionally fixed a priori, we let the partition be a model parameter and propose a Bayesian method for inference. The challenge is that demand systems are commonly multivariate models that are not conditionally conjugate…

多状态隐马尔可夫模型的贝叶斯方法：痴呆进展应用AI 解读

People are living longer than ever before, and with this arises new complications and challenges for humanity. Among the most pressing of these challenges is of understanding the role of aging in the development of dementia. This article is motivated by the Mayo Clinic Study of Aging data for 4742 subjects since 2004, and how it can be used to draw inference on the role of aging in the development of dementia. We construct a hidden Markov model (HMM) to represent progression…

用于分组数据聚类的分层归一化完全随机测度AI 解读

In this article, we propose a Bayesian nonparametric model for clustering grouped data. We adopt a hierarchical approach: at the highest level, each group of data is modeled according to a mixture, where the mixing distributions are conditionally independent normalized completely random measures (NormCRMs) centered on the same base measure, which is itself a NormCRM. The discreteness of the shared base measure implies that the processes at the data level share the same…

元分析中未测量混杂的敏感性分析AI 解读

Random-effects meta-analyses of observational studies can produce biased estimates if the synthesized studies are subject to unmeasured confounding. We propose sensitivity analyses quantifying the extent to which unmeasured confounding of specified magnitude could reduce to below a certain threshold the proportion of true effect sizes that are scientifically meaningful. We also develop converse methods to estimate the strength of confounding capable of reducing the…

L2RM：高维矩阵响应的低秩线性回归模型AI 解读

The aim of this paper is to develop a low-rank linear regression model (L2RM) to correlate a high-dimensional response matrix with a high dimensional vector of covariates when coefficient matrices have low-rank structures. We propose a fast and efficient screening procedure based on the spectral norm of each coefficient matrix in order to deal with the case when the number of covariates is extremely large. We develop an efficient estimation procedure based on the trace norm…

对称误差下潜在变量边界的估计AI 解读

Consider the model Y=X+ε with X=τ+Z, where τ is an unknown constant (the boundary of X), Z is a random variable defined on R+, ε is a symmetric error, and ε and Z are independent. Based on an iid sample of Y, we aim at identifying and estimating the boundary τ when the law of ε is unknown (apart from symmetry) and in particular its variance is unknown. We propose an estimation procedure based on a minimal distance approach and by making use of Laguerre polynomials.…

柯西组合检验：任意依赖结构下的解析 p 值计算AI 解读

–Combining individual p-values to aggregate multiple small effects has a long-standing interest in statistics, dating back to the classic Fisher’s combination test. In modern large-scale data analysis, correlation and sparsity are common features and efficient computation is a necessary requirement for dealing with massive data. To overcome these challenges, we propose a new test that takes advantage of the Cauchy distribution. Our test statistic has a simple form and is…

高维模型中处理效应的去偏推断AI 解读

This article concerns the potential bias in statistical inference on treatment effects when a large number of covariates are present in a linear or partially linear model. While the estimation bias in an under-fitted model is well understood, we address a lesser-known bias that arises from an over-fitted model. The over-fitting bias can be eliminated through data splitting at the cost of statistical efficiency, and we show that smoothing over random data splits can be…

自适应 Huber 回归AI 解读

Big data can easily be contaminated by outliers or contain variables with heavy-tailed distributions, which makes many conventional methods inadequate. To address this challenge, we propose the adaptive Huber regression for robust estimation and inference. The key observation is that the robustification parameter should adapt to the sample size, dimension and moments for optimal tradeoff between bias and robustness. Our theoretical framework deals with heavy-tailed…

抽样网络数据下随机块模型的变分推断AI 解读

This article deals with nonobserved dyads during the sampling of a network and consecutive issues in the inference of the stochastic block model (SBM). We review sampling designs and recover missing at random (MAR) and not missing at random (NMAR) conditions for the SBM. We introduce variants of the variational EM algorithm for inferring the SBM under various sampling designs (MAR and NMAR) all available as an R package. Model selection criteria based on integrated…

协变量缺失时基于群组检测数据估计条件患病率AI 解读

We consider estimating the conditional prevalence of a disease from data pooled according to the group testing mechanism. Consistent estimators have been proposed in the literature, but they rely on the data being available for all individuals. In infectious disease studies where group testing is frequently applied, the covariate is often missing for some individuals. There, unless the missing mechanism occurs completely at random, applying the existing techniques to the…

基于数据深度的非参数缺失值插补AI 解读

We present single imputation method for missing values which borrows the idea of data depth—a measure of centrality defined for an arbitrary point of a space with respect to a probability distribution or data cloud. This consists in iterative maximization of the depth of each observation with missing values, and can be employed with any properly defined statistical depth function. For each single iteration, imputation reverts to optimization of quadratic, linear, or…

球协方差：Banach 空间中的通用依赖度量AI 解读

Technological advances in science and engineering have led to the routine collection of large and complex data objects, where the dependence structure among those objects is often of great interest. Those complex objects (e.g, different brain subcortical structures) often reside in some Banach spaces, and hence their relationship cannot be well characterized by most of the existing measures of dependence such as correlation coefficients developed in Hilbert spaces. To…

RANK：基于图结构非线性 Knockoffs 的大规模推断AI 解读

Power and reproducibility are key to enabling refined scientific discoveries in contemporary big data applications with general high-dimensional nonlinear models. In this paper, we provide theoretical foundations on the power and robustness for the model-X knockoffs procedure introduced recently in Candès, Fan, Janson and Lv (2018) in high-dimensional setting when the covariate distribution is characterized by Gaussian graphical model. We establish that under mild regularity…

金融市场的分位数共同变动：含不可观测异质性的面板分位数模型AI 解读

This article introduces a new procedure for analyzing the quantile co-movement of a large number of financial time series based on a large-scale panel data model with factor structures. The proposed method attempts to capture the unobservable heterogeneity of each of the financial time series based on sensitivity to explanatory variables and to the unobservable factor structure. In our model, the dimension of the common factor structure varies across quantiles, and the…

内生处理下异质性个体处理效应的估计AI 解读

This article estimates individual treatment effects (ITE) and its probability distribution in a triangular model with binary-valued endogenous treatments. Our estimation procedure takes two steps. First, we estimate the counterfactual outcome and hence, the ITE for every observational unit in the sample. Second, we estimate the ITE density function of the whole population. Our estimation method does not suffer from the ill-posed inverse problem associated with inverting a…

高维约束最大似然推断AI 解读

Inference in a high-dimensional situation may involve regularization of a certain form to treat overparameterization, imposing challenges to inference. The common practice of inference uses either a regularized model, as in inference after model selection, or bias-reduction known as “debias.” While the first ignores statistical uncertainty inherent in regularization, the second reduces the bias inbred in regularization at the expense of increased variance. In this article,…

从距离相关到多尺度图相关AI 解读

Understanding and developing a correlation measure that can detect general dependencies is not only imperative to statistics and machine learning, but also crucial to general scientific discovery in the big data age. In this paper, we establish a new framework that generalizes distance correlation (Dcorr)—a correlation measure that was recently proposed and shown to be universally consistent for dependence testing against all joint distributions of finite moments—to the…

贝叶斯排斥型高斯混合模型AI 解读

We develop a general class of Bayesian repulsive Gaussian mixture models that encourage well-separated clusters, aiming at reducing potentially redundant components produced by independent priors for locations (such as the Dirichlet process). The asymptotic results for the posterior distribution of the proposed models are derived, including posterior consistency and posterior contraction rate in the context of nonparametric density estimation. More importantly, we show that…