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Distribution-Free Consistent Independence Tests via Center-Outward Ranks and Signs

基于中心向外秩与符号的分布无关一致独立性检验

This article investigates the problem of testing independence of two random vectors of general dimensions. For this, we give for the first time a distribution-free consistent test. Our approach combines distance covariance with the center-outward ranks and signs developed by Marc Hallin and collaborators. In technical terms, the proposed test is consistent and distribution-free in the family of multivariate distributions with nonvanishing (Lebesgue) probability densities.…

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Covariate Adaptive False Discovery Rate Control With Applications to Omics-Wide Multiple Testing

协变量自适应的错误发现率控制及组学多重检验应用

Conventional multiple testing procedures often assume hypotheses for different features are exchangeable. However, in many scientific applications, additional covariate information regarding the patterns of signals and nulls are available. In this article, we introduce an FDR control procedure in large-scale inference problem that can incorporate covariate information. We develop a fast algorithm to implement the proposed procedure and prove its asymptotic validity even when…

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Model-Free Feature Screening and FDR Control With Knockoff Features

利用 Knockoff 特征进行无模型特征筛选与错误发现率控制

This article proposes a model-free and data-adaptive feature screening method for ultrahigh-dimensional data. The proposed method is based on the projection correlation which measures the dependence between two random vectors. This projection correlation based method does not require specifying a regression model, and applies to data in the presence of heavy tails and multivariate responses. It enjoys both sure screening and rank consistency properties under weak…

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Estimation of Subgraph Densities in Noisy Networks

含噪网络中的子图密度估计

While it is common practice in applied network analysis to report various standard network summary statistics, these numbers are rarely accompanied by uncertainty quantification. Yet any error inherent in the measurements underlying the construction of the network, or in the network construction procedure itself, necessarily must propagate to any summary statistics reported. Here we study the problem of estimating the density of an arbitrary subgraph, given a noisy version…

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Detection of Local Differences in Spatial Characteristics Between Two Spatiotemporal Random Fields

两个时空随机场空间特征局部差异的检测

Comparing the spatial characteristics of spatiotemporal random fields is often at demand. However, the comparison can be challenging due to the high-dimensional feature and dependency in the data. We develop a new multiple testing approach to detect local differences in the spatial characteristics of two spatiotemporal random fields by taking the spatial information into account. Our method adopts a two-component mixture model for location wise p-values and then derives a…

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An Empirical Bayes Method for Chi-Squared Data

卡方数据的经验贝叶斯方法

In a thought-provoking paper, Efron investigated the merit and limitation of an empirical Bayes method to correct selection bias based on Tweedie’s formula first reported in the study by Robbins. The exceptional virtue of Tweedie’s formula for the normal distribution lies in its representation of selection bias as a simple function of the derivative of log marginal likelihood. Since the marginal likelihood and its derivative can be estimated from the data directly without…

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Regularized Optimal Transport of Covariates and Outcomes in Data Recoding

数据重编码中协变量与结果的正则化最优传输

When databases are constructed from heterogeneous sources, it is not unusual that different encodings are used for the same outcome. In such case, it is necessary to recode the outcome variable before merging two databases. The method proposed for the recoding is an application of optimal transportation where we search for a bijective mapping between the distributions of such variable in two databases. In this article, we build upon the work by Garés et al., where they…

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Optimal Distributed Subsampling for Maximum Quasi-Likelihood Estimators With Massive Data

海量数据下最大准似然估计的最优分布式子抽样

Nonuniform subsampling methods are effective to reduce computational burden and maintain estimation efficiency for massive data. Existing methods mostly focus on subsampling with replacement due to its high computational efficiency. If the data volume is so large that nonuniform subsampling probabilities cannot be calculated all at once, then subsampling with replacement is infeasible to implement. This article solves this problem using Poisson subsampling. We first derive…

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Estimating and Accounting for Unobserved Covariates in High-Dimensional Correlated Data

高维相关数据中未观测协变量的估计与调整

Many high dimensional and high-throughput biological datasets have complex sample correlation structures, which include longitudinal and multiple tissue data, as well as data with multiple treatment conditions or related individuals. These data, as well as nearly all high-throughput 'omic' data, are influenced by technical and biological factors unknown to the researcher, which, if unaccounted for, can severely obfuscate estimation of and inference on the effects of…

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A Multiple-Testing Procedure for High-Dimensional Mediation Hypotheses

高维中介假设的多重检验程序

Mediation analysis is of rising interest in epidemiology and clinical trials. Among existing methods, the joint significance (JS) test yields an overly conservative type I error rate and low power, particularly for high-dimensional mediation hypotheses. In this article we develop a multiple-testing procedure that accurately controls the family-wise error rate (FWER) and the false discovery rate (FDR) when testing high-dimensional mediation hypotheses. The core of our…

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Separable Effects for Causal Inference in the Presence of Competing Events

存在竞争事件时用于因果推断的可分离效应

In time-to-event settings, the presence of competing events complicates the definition of causal effects. Here we propose the new separable effects to study the causal effect of a treatment on an event of interest. The separable direct effect is the treatment effect on the event of interest not mediated by its effect on the competing event. The separable indirect effect is the treatment effect on the event of interest only through its effect on the competing event. Similar…

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Testing for Balance in Social Networks

社会网络平衡性检验

Friendship and antipathy exist in concert with one another in real social networks. Despite the role they play in social interactions, antagonistic ties are poorly understood and infrequently measured. One important theory of negative ties that has received relatively little empirical evaluation is balance theory, the codification of the adage “the enemy of my enemy is my friend” and similar sayings. Unbalanced triangles are those with an odd number of negative ties, and the…

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Spectral Inference under Complex Temporal Dynamics

复杂时间动态下的谱推断

We develop a unified theory and methodology for the inference of evolutionary Fourier power spectra for a general class of locally stationary and possibly nonlinear processes. In particular, simultaneous confidence regions (SCR) with asymptotically correct coverage rates are constructed for the evolutionary spectral densities on a nearly optimally dense grid of the joint time-frequency domain. A simulation based bootstrap method is proposed to implement the SCR. The SCR…

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Functional Linear Regression: Dependence and Error Contamination

函数型线性回归:序列依赖与误差污染

Functional linear regression is an important topic in functional data analysis. It is commonly assumed that samples of the functional predictor are independent realizations of an underlying stochastic process, and are observed over a grid of points contaminated by iid measurement errors. In practice, however, the dynamical dependence across different curves may exist and the parametric assumption on the error covariance structure could be unrealistic. In this article, we…

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Homogeneity and Structure Identification in Semiparametric Factor Models

半参数因子模型中的同质性与结构识别

Factor modeling is an essential tool for exploring intrinsic dependence structures in financial and economic studies through the construction of common latent variables, including the famous Fama–French three factor models for the description of asset returns in finance. However, most of the existing statistical methods for analyzing latent factors have been developed through a linear approach. In this article, we consider a semiparametric factor model and present a…

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A Projective Approach to Conditional Independence Test for Dependent Processes

依赖过程条件独立检验的投影方法

Conditional independence is a fundamental concept in many scientific fields. In this article, we propose a projective approach to measuring and testing departure from conditional independence for dependent processes. Through projecting high-dimensional dependent processes on to low-dimensional subspaces, our proposed projective approach is insensitive to the dimensions of the processes. We show that, under the common β-mixing conditions, our proposed projective test…

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Nonlinear Predictability of Stock Returns? Parametric Versus Nonparametric Inference in Predictive Regressions

股票收益的非线性可预测性?预测回归中的参数与非参数推断

Nonparametric test procedures in predictive regressions have χ2 limiting null distributions under both low and high regressor persistence, but low local power compared to misspecified linear predictive regressions. We argue that IV inference is better suited (in terms of local power) for analyzing additive predictive models with uncertain predictor persistence. Then, a two-step procedure is proposed for out-of-sample predictions. For the current estimation window, one first…

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Nonparametric Estimation and Conformal Inference of the Sufficient Forecasting With a Diverging Number of Factors

因子数增长时充分预测的非参数估计与共形推断

The sufficient forecasting (SF) provides a nonparametric procedure to estimate forecasting indices from high-dimensional predictors to forecast a single time series, allowing for the possibly nonlinear forecasting function. This article studies the asymptotic theory of the SF with a diverging number of factors and develops its predictive inference. First, we revisit the SF and explore its connections to Fama–MacBeth regression and partial least squares. Second, with a…

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Identification of Structural Vector Autoregressions by Stochastic Volatility

利用随机波动识别结构向量自回归

We propose to exploit stochastic volatility for statistical identification of structural vector autoregressive models (SV-SVAR). We discuss full and partial identification of the model and develop efficient EM algorithms for maximum likelihood inference. Simulation evidence suggests that the SV-SVAR works well in identifying structural parameters also under misspecification of the variance process, particularly if compared to alternative heteroscedastic SVARs. We apply the…

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Estimation of Conditional Average Treatment Effects With High-Dimensional Data

高维数据下条件平均处理效应的估计

Given the unconfoundedness assumption, we propose new nonparametric estimators for the reduced dimensional conditional average treatment effect (CATE) function. In the first stage, the nuisance functions necessary for identifying CATE are estimated by machine learning methods, allowing the number of covariates to be comparable to or larger than the sample size. The second stage consists of a low-dimensional local linear regression, reducing CATE to a function of the…

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Counterfactual Treatment Effects: Estimation and Inference

反事实处理效应:估计与推断

This article proposes statistical methods to evaluate the quantile counterfactual treatment effect (QCTE) if one were to change the composition of the population targeted by a status quo program. QCTE enables a researcher to carry out an ex-ante assessment of the distributional impact of certain policy interventions or to investigate the possible explanations for treatment effect heterogeneity. Assuming unconfoundedness and invariance of the conditional distributions of the…

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Counterfactual Analysis and Inference With Nonstationary Data

非平稳数据下的反事实分析与推断

Recently, there has been growing interest in developing econometric tools to conduct counterfactual analysis with aggregate data when a single “treated” unit suffers an intervention, such as a policy change, and there is no obvious control group. Usually, the proposed methods are based on the construction of an artificial/synthetic counterfactual from a pool of “untreated” peers, organized in a panel data structure. In this article, we investigate the consequences of…

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Mean-Structure and Autocorrelation Consistent Covariance Matrix Estimation

均值结构与自相关稳健的协方差矩阵估计

We consider estimation of the asymptotic covariance matrix in nonstationary time series. A nonparametric estimator that is robust against unknown forms of trends and possibly a divergent number of change points (CPs) is proposed. It is algorithmically fast because neither a search for CPs, estimation of trends, nor cross-validation is required. Together with our proposed automatic optimal bandwidth selector, the resulting estimator is both statistically and computationally…

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In Search of a Job: Forecasting Employment Growth Using Google Trends

寻找工作:利用Google Trends预测就业增长

We show that Google search activity on relevant terms is a strong out-of-sample predictor for future employment growth in the United States over the period 2004–2019 at both short and long horizons. Starting from an initial search term “jobs,” we construct a large panel of 172 variables using Google’s own algorithms to find semantically related search queries. The best Google Trends model achieves an out-of-sample R2 between 29% and 62% at horizons spanning from one month to…

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