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Modelling the COVID-19 Infection Trajectory: A Piecewise Linear Quantile Trend Model

COVID-19 感染轨迹建模:分段线性分位数趋势模型

Abstract We propose a piecewise linear quantile trend model to analyse the trajectory of the COVID-19 daily new cases (i.e. the infection curve) simultaneously across multiple quantiles. The model is intuitive, interpretable and naturally captures the phase transitions of the epidemic growth rate via change-points. Unlike the mean trend model and least squares estimation, our quantile-based approach is robust to outliers, captures heteroscedasticity (commonly exhibited by…

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Tail and center rounding of probabilistic expectations in the Health and Retirement Study

健康与退休研究中概率预期的尾部与中心舍入

We study rounding of numerical expectations in the Health and Retirement Study (HRS) between 2002 and 2014. We document that respondent-specific rounding patterns across questions in individual waves are quite stable across waves. We discover a tendency by about half of the respondents to provide more refined responses in the tails of the 0–100 scale than the center. In contrast, only about five percent of the respondents give more refined responses in the center than the…

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Forecasting low‐frequency macroeconomic events with high‐frequency data

利用高频数据预测低频宏观事件

Summary High‐frequency financial and economic indicators are usually time‐aggregated before computing forecasts of macroeconomic events, such as recessions. We propose a mixed‐frequency alternative that delivers high‐frequency probability forecasts (including their confidence bands) for low‐frequency events. The new approach is compared with single‐frequency alternatives using loss functions for rare‐event forecasting. We find (i) the weekly‐sampled term spread improves over…

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Long‐run predictability tests are even worse than you thought

长期预测能力检验比你想象的更糟

Summary We derive asymptotic results for the long‐horizon ordinary least squares (OLS) estimator and corresponding ‐statistic for stationary autoregressive predictors. The ‐statistic—formed using the correct asymptotic variance—together with standard‐normal critical values result in a correctly‐sized test for exogenous predictors. For endogenous predictors, the test is size distorted regardless of the persistence in the predictor and adjusted critical values are necessary.…

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Normal but skewed?

正态,却有偏态?

Summary We propose a multivariate normality test against skew normal distributions using higher‐order log‐likelihood derivatives, which is asymptotically equivalent to the likelihood ratio but only requires estimation under the null. Numerically, it is the supremum of the univariate skewness coefficient test over all linear combinations of the variables. We can simulate its exact finite sample distribution for any multivariate dimension and sample size. Our Monte Carlo…

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Regression with an imputed dependent variable

使用插补因变量的回归

Summary Researchers are often interested in the relationship between two variables, with no single data set containing both. A common strategy is to use proxies for the dependent variable that are common to two surveys to impute the dependent variable into the data set containing the independent variable. We show that commonly employed regression or matching‐based imputation procedures lead to inconsistent estimates. We offer a consistent and easily implemented two‐step…

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Inference on Multi-level Partial Correlations Based on Multi-subject Time Series Data

基于多受试者时间序列的多层偏相关推断

Partial correlations are commonly used to analyze the conditional dependence among variables. In this work, we propose a hierarchical model to study both the subject- and population-level partial correlations based on multi-subject time-series data. Multiple testing procedures adaptive to temporally dependent data with false discovery proportion control are proposed to identify the nonzero partial correlations in both the subject and population levels. A computationally…

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Modeling Time-Varying Random Objects and Dynamic Networks

时变随机对象与动态网络的建模

Samples of dynamic or time-varying networks and other random object data such as time-varying probability distributions are increasingly encountered in modern data analysis. Common methods for time-varying data such as functional data analysis are infeasible when observations are time courses of networks or other complex non-Euclidean random objects that are elements of general metric spaces. In such spaces, only pairwise distances between the data objects are available and…

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Inference of Breakpoints in High-dimensional Time Series

高维时间序列的断点推断

For multiple change-points detection of high-dimensional time series, we provide asymptotic theory concerning the consistency and the asymptotic distribution of the breakpoint statistics and estimated break sizes. The theory backs up a simple two-step procedure for detecting and estimating multiple change-points. The proposed two-step procedure involves the maximum of a MOSUM (moving sum) type statistics in the first step and a CUSUM (cumulative sum) refinement step on an…

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Testing Independence Under Biased Sampling

有偏抽样下的独立性检验

Testing for dependence between pairs of random variables is a fundamental problem in statistics. In some applications, data are subject to selection bias that can create spurious dependence. An important example is truncation models, in which observed pairs are restricted to a specific subset of the X-Y plane. Standard tests for independence are not suitable in such cases, and alternative tests that take the selection bias into account are required. Here, we generalize the…

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Single-index Thresholding in Quantile Regression

分位数回归中的单指标门限模型

Threshold regression models are useful for identifying subgroups with heterogeneous parameters. The conventional threshold regression models split the sample based on a single and observed threshold variable, which enforces the threshold point to be equal for all subgroups of the population. In this article, we consider a more flexible single-index threshold model in the quantile regression setup, in which the sample is split based on a linear combination of predictors. We…

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Integrative Factor Regression and Its Inference for Multimodal Data Analysis

多模态数据的整合因子回归及其推断

Multimodal data, where different types of data are collected from the same subjects, are fast emerging in a large variety of scientific applications. Factor analysis is commonly used in integrative analysis of multimodal data, and is particularly useful to overcome the curse of high dimensionality and high correlations. However, there is little work on statistical inference for factor analysis based supervised modeling of multimodal data. In this article, we consider an…

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Gradient-Based Markov Chain Monte Carlo for Bayesian Inference With Non-differentiable Priors

非可微先验下贝叶斯推断的梯度型 MCMC

The use of nondifferentiable priors in Bayesian statistics has become increasingly popular, in particular in Bayesian imaging analysis. Current state-of-the-art methods are approximate in the sense that they replace the posterior with a smooth approximation via Moreau-Yosida envelopes, and apply gradient-based discretized diffusions to sample from the resulting distribution. We characterize the error of the Moreau-Yosida approximation and propose a novel implementation using…

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Semi-Supervised Linear Regression

半监督线性回归

We study a regression problem where for some part of the data we observe both the label variable (Y) and the predictors (X), while for other part of the data only the predictors are given. Such a problem arises, for example, when observations of the label variable are costly and may require a skilled human agent. When the conditional expectation E[Y|X] is not exactly linear, one can consider the best linear approximation to the conditional expectation, which can be estimated…

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Design-Based Ratio Estimators and Central Limit Theorems for Clustered, Blocked RCTs

聚类分区随机试验的设计型比率估计与中心极限定理

This article develops design-based ratio estimators for clustered, blocked randomized controlled trials (RCTs), with an application to a federally funded, school-based RCT testing the effects of behavioral health interventions. We consider finite population weighted least-square estimators for average treatment effects (ATEs), allowing for general weighting schemes and covariates. We consider models with block-by-treatment status interactions as well as restricted models…

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Generalized Bayes Quantification Learning under Dataset Shift

数据集偏移下的广义贝叶斯类别比例学习

Quantification learning is the task of prevalence estimation for a test population using predictions from a classifier trained on a different population. Quantification methods assume that the sensitivities and specificities of the classifier are either perfect or transportable from the training to the test population. These assumptions are inappropriate in the presence of dataset shift, when the misclassification rates in the training population are not representative of…

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Nonparametric Fusion Learning for Multiparameters: Synthesize Inferences From Diverse Sources Using Data Depth and Confidence Distribution

多参数非参数融合学习:结合数据深度与置信分布

Fusion learning refers to synthesizing inferences from multiple sources or studies to make a more effective inference and prediction than from any individual source or study alone. Most existing methods for synthesizing inferences rely on parametric model assumptions, such as normality, which often do not hold in practice. We propose a general nonparametric fusion learning framework for synthesizing inferences for multiparameters from different studies. The main tool…

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Inference in Experiments With Matched Pairs

配对随机实验中的推断

This article studies inference for the average treatment effect in randomized controlled trials where treatment status is determined according to a “matched pairs” design. By a “matched pairs” design, we mean that units are sampled iid from the population of interest, paired according to observed, baseline covariates and finally, within each pair, one unit is selected at random for treatment. This type of design is used routinely throughout the sciences, but fundamental…

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Adaptive Inference for Change Points in High-Dimensional Data

高维数据变点的自适应推断

In this article, we propose a class of test statistics for a change point in the mean of high-dimensional independent data. Our test integrates the U-statistic based approach in a recent work by Wang et al. and the Lq-norm based high-dimensional test in a recent work by He et al., and inherits several appealing features such as being tuning parameter free and asymptotic independence for test statistics corresponding to even q’s. A simple combination of test statistics…

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Linear Hypothesis Testing in Linear Models With High-Dimensional Responses

高维响应线性模型中的线性假设检验

In this paper, we propose a new projection test for linear hypotheses on regression coefficient matrices in linear models with high dimensional responses. We systematically study the theoretical properties of the proposed test. We first derive the optimal projection matrix for any given projection dimension to achieve the best power and provide an upper bound for the optimal dimension of projection matrix. We further provide insights into how to construct the optimal…

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Kernel Ordinary Differential Equations

核常微分方程

Ordinary differential equation (ODE) is widely used in modeling biological and physical processes in science. In this article, we propose a new reproducing kernel-based approach for estimation and inference of ODE given noisy observations. We do not assume the functional forms in ODE to be known, or restrict them to be linear or additive, and we allow pairwise interactions. We perform sparse estimation to select individual functionals, and construct confidence intervals for…

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Risk Projection for Time-to-Event Outcome Leveraging Summary Statistics With Source Individual-Level Data

结合目标总体汇总统计与源总体个体数据的事件发生风险外推

Predicting risks of chronic diseases has become increasingly important in clinical practice. When a prediction model is developed in a cohort, there is a great interest to apply the model to other cohorts. Due to potential discrepancy in baseline disease incidences between different cohorts and shifts in patient composition, the risk predicted by the model built in the source cohort often under- or over-estimates the risk in a new cohort. In this article, we assume the…

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Robust Two-Step Wavelet-Based Inference for Time Series Models

时间序列模型的稳健两步小波推断

) models with additional stochastic processes are increasingly used for data analysis in biology, ecology, engineering, and economics. Inference on and/or prediction from these models can be highly challenging: (i) the data may contain outliers that can adversely affect the estimation procedure; (ii) the computational complexity can become prohibitive when the time series are extremely large; (iii) model selection adds another layer of (computational) complexity; and (iv)…

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On Characterizations and Tests of Benford’s Law

本福特定律的刻画与检验

Benford’s law defines a probability distribution for patterns of significant digits in real numbers. When the law is expected to hold for genuine observations, deviation from it can be taken as evidence of possible data manipulation. We derive results on a transform of the significand function that provide motivation for new tests of conformance to Benford’s law exploiting its sum-invariance characterization. We also study the connection between sum invariance of the first…

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