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Inference for treatment effect parameters in potentially misspecified high-dimensional models

可能误设的高维模型中处理效应参数的推断

Summary Eliminating the effect of confounding in observational studies typically involves fitting a model for an outcome adjusted for covariates. When, as often, these covariates are high-dimensional, this necessitates the use of sparse estimators, such as the lasso, or other regularization approaches. Naïve use of such estimators yields confidence intervals for the conditional treatment effect parameter that are not uniformly valid. Moreover, as the number of covariates…

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On the use of a penalized quasilikelihood information criterion for generalized linear mixed models

广义线性混合模型的惩罚拟似然信息准则

Summary Information criteria are commonly used for joint fixed and random effects selection in mixed models. While information criteria are straightforward to implement, a major difficulty in applying them is that they are typically based on maximum likelihood estimates, but calculating such estimates for one candidate mixed model, let alone multiple models, presents a major computational challenge. To overcome this hurdle, we study penalized quasilikelihood estimation and…

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Approximating posteriors with high-dimensional nuisance parameters via integrated rotated Gaussian approximation

通过积分旋转高斯近似处理高维干扰参数的后验近似

Summary Posterior computation for high-dimensional data with many parameters can be challenging. This article focuses on a new method for approximating posterior distributions of a low- to moderate-dimensional parameter in the presence of a high-dimensional or otherwise computationally challenging nuisance parameter. The focus is on regression models and the key idea is to separate the likelihood into two components through a rotation. One component involves only the…

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Poisson reduced-rank models with an application to political text data

泊松降秩模型及其在政治文本数据中的应用

Summary We discuss Poisson reduced-rank models for low-dimensional summaries of high-dimensional Poisson vectors that allow inference on the location of individuals in a low-dimensional space. We show that under weak dependence conditions, which allow for certain correlations between the Poisson random variables, the locations can be consistently estimated using Poisson maximum likelihood estimation. Moreover, we develop consistent rules for determining the dimension of the…

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High dimensional minimum variance portfolio estimation under statistical factor models

统计因子模型下的高维最小方差组合估计

We propose a high dimensional minimum variance portfolio estimator under statistical factor models, and show that our estimated portfolio enjoys sharp risk consistency. Our approach relies on properly integrating ℓ1 constraint on portfolio weights with an appropriate covariance matrix estimator. In terms of covariance matrix estimation, we extend the theoretical results of POET (Fan et al., 2013) to a setting that is coherent with principal component analysis. Simulation and…

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(Machine) learning parameter regions

用机器学习刻画参数区域

How many random points from an identified set, a confidence set, or a highest posterior density set suffice to describe them? This paper argues that taking random draws from a parameter region in order to approximate its shape is a supervised learning problem (analogous to sampling pixels of an image to recognize it). Misclassification error – a common criterion in machine learning – provides an off-the-shelf tool to assess the quality of a given approximation. We say a…

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Bayesian MIDAS penalized regressions: Estimation, selection, and prediction

贝叶斯MIDAS惩罚回归:估计、选择与预测

We propose a new approach to mixed-frequency regressions in a high-dimensional environment that resorts to Group Lasso penalization and Bayesian estimation and inference. In particular, to improve the prediction properties of the model and its sparse recovery ability, we consider a Group Lasso with a spike-and-slab prior. Penalty hyper-parameters governing the model shrinkage are automatically tuned via an adaptive MCMC algorithm. We establish good frequentist asymptotic…

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Time-varying general dynamic factor models and the measurement of financial connectedness

时变广义动态因子模型与金融关联度测量

We propose a new time-varying Generalized Dynamic Factor Model for high-dimensional, locally stationary time series. Estimation is based on dynamic principal component analysis jointly with singular VAR estimation, and extends to the locally stationary case the one-sided estimation method proposed by Forni et al. (2017) for stationary data. We prove consistency of our estimators of time-varying impulse response functions as both the sample size T and the dimension n of the…

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Max-linear regression models with regularization

带正则化的最大线性回归模型

Motivated by the newly developed max-linear competing copula factor models and max-stable nonlinear time series models, we propose a new class of max-linear regression models to take advantages of easy interpretable features embedded in linear regression models. It can be seen that linear relation is a special case of max-linear relation. We develop an EM algorithm based maximum likelihood estimation procedure. The consistency and asymptotics of the estimators for parameters…

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Using penalized likelihood to select parameters in a random coefficients multinomial logit model

随机系数多项 Logit 模型中的惩罚似然参数选择

This paper is about estimating a random coefficients logit model in which the distribution of each coefficient is characterized by finitely many parameters, some of which may be zero. The paper gives conditions under which, with probability approaching 1 as the sample size increases, penalized maximum likelihood (PML) estimation with the adaptive LASSO (AL) penalty distinguishes correctly between zero and non-zero parameters. The paper also gives conditions under which PML…

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Log-Linear Bayesian Additive Regression Trees for Multinomial Logistic and Count Regression Models

多项 Logistic 与计数回归的对数线性贝叶斯加性回归树

We introduce Bayesian additive regression trees (BART) for log-linear models including multinomial logistic regression and count regression with zero-inflation and overdispersion. BART has been applied to nonparametric mean regression and binary classification problems in a range of settings. However, existing applications of BART have been mostly limited to models for Gaussian “data,” either observed or latent. This is primarily because efficient MCMC algorithms are…

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The Interplay of Demographic Variables and Social Distancing Scores in Deep Prediction of U.S. COVID-19 Cases

人口特征与社交距离指标在美国COVID-19病例深度预测中的作用

With the severity of the COVID-19 outbreak, we characterize the nature of the growth trajectories of counties in the United States using a novel combination of spectral clustering and the correlation matrix. As the United States and the rest of the world are still suffering from the effects of the virus, the importance of assigning growth membership to counties and understanding the determinants of the growth is increasingly evident. For the two communities (faster versus…

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Modeling Multiple Time-Varying Related Groups: A Dynamic Hierarchical Bayesian Approach With an Application to the Health and Retirement Study

多个时变关联群组的建模:动态层次贝叶斯方法及其在健康与退休研究中的应用

As the population of the older individuals continues to grow, it is important to study the relationship among the variables measuring financial health and physical health of the older individuals to better understand the demand for healthcare, and health insurance. We propose a semiparametric approach to jointly model these variables. We use data from the Health and Retirement Study which includes a set of correlated longitudinal variables measuring financial and physical…

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Parametric Modeling of Quantile Regression Coefficient Functions With Longitudinal Data

纵向数据分位数回归系数函数的参数化建模

In ordinary quantile regression, quantiles of different order are estimated one at a time. An alternative approach, which is referred to as quantile regression coefficients modeling (qrcm), is to model quantile regression coefficients as parametric functions of the order of the quantile. In this article, we describe how the qrcm paradigm can be applied to longitudinal data. We introduce a two-level quantile function, in which two different quantile regression models are used…

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Privacy-Preserving Parametric Inference: A Case for Robust Statistics

保护隐私的参数推断:稳健统计的作用

Differential privacy is a cryptographically motivated approach to privacy that has become a very active field of research over the last decade in theoretical computer science and machine learning. In this paradigm, one assumes there is a trusted curator who holds the data of individuals in a database and the goal of privacy is to simultaneously protect individual data while allowing the release of global characteristics of the database. In this setting, we introduce a…

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Rare Feature Selection in High Dimensions

高维稀有特征选择

It is common in modern prediction problems for many predictor variables to be counts of rarely occurring events. This leads to design matrices in which many columns are highly sparse. The challenge posed by such “rare features” has received little attention despite its prevalence in diverse areas, ranging from natural language processing (e.g., rare words) to biology (e.g., rare species). We show, both theoretically and empirically, that not explicitly accounting for the…

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Bias and High-Dimensional Adjustment in Observational Studies of Peer Effects

同伴效应观察性研究中的偏差与高维调整

Peer effects, in which an individual’s behavior is affected by peers’ behavior, are posited by multiple theories in the social sciences. Randomized field experiments that identify peer effects, however, are often expensive or infeasible, so many studies of peer effects use observational data, which is expected to suffer from confounding. Here we show, in the context of information and media diffusion, that high-dimensional adjustment of a nonexperimental control group (660…

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Bayesian Joint Modeling of Multiple Brain Functional Networks

多个脑功能网络的贝叶斯联合建模

Investigating the similarity and changes in brain networks under different mental conditions has become increasingly important in neuroscience research. A standard separate estimation strategy fails to pool information across networks and hence has reduced estimation accuracy and power to detect between-network differences. Motivated by a fMRI Stroop task experiment that involves multiple related tasks, we develop an integrative Bayesian approach for jointly modeling…

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Bayesian Structure Learning in Multilayered Genomic Networks

多层基因组网络中的贝叶斯结构学习

Integrative network modeling of data arising from multiple genomic platforms provides insight into the holistic picture of the interactive system, as well as the flow of information across many disease domains including cancer. The basic data structure consists of a sequence of hierarchically ordered datasets for each individual subject, which facilitates integration of diverse inputs, such as genomic, transcriptomic, and proteomic data. A primary analytical task in such…

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Nonbifurcating Phylogenetic Tree Inference via the Adaptive LASSO

通过自适应 LASSO 推断非二叉系统发育树

Phylogenetic tree inference using deep DNA sequencing is reshaping our understanding of rapidly evolving systems, such as the within-host battle between viruses and the immune system. Densely sampled phylogenetic trees can contain special features, including sampled ancestors in which we sequence a genotype along with its direct descendants, and polytomies in which multiple descendants arise simultaneously. These features are apparent after identifying zero-length branches…

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Bayesian Regression With Undirected Network Predictors With an Application to Brain Connectome Data

以无向网络为预测变量的贝叶斯回归:脑连接组应用

This article focuses on the relationship between a measure of creativity and the human brain network for subjects in a brain connectome dataset obtained using a diffusion weighted magnetic resonance imaging procedure. We identify brain regions and interconnections that have a significant effect on creativity. Brain networks are often expressed in terms of symmetric adjacency matrices, with row and column indices of the matrix representing the regions of interest (ROI), and a…

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On the Length of Post-Model-Selection Confidence Intervals Conditional on Polyhedral Constraints

多面体约束条件下模型选择后置信区间的长度

Valid inference after model selection is currently a very active area of research. The polyhedral method, pioneered by Lee, et al. (2016), allows for valid inference after model selection if the model selection event can be described by polyhedral constraints. In that reference, the method is exemplified by constructing two valid confidence intervals when the Lasso estimator is used to select a model. We here study the length of these intervals. For one of these confidence…

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A Distributed and Integrated Method of Moments for High-Dimensional Correlated Data Analysis

高维相关数据分析的分布式整合矩方法

This paper is motivated by a regression analysis of electroencephalography (EEG) neuroimaging data with high-dimensional correlated responses with multi-level nested correlations. We develop a divide-and-conquer procedure implemented in a fully distributed and parallelized computational scheme for statistical estimation and inference of regression parameters. Despite significant efforts in the literature, the computational bottleneck associated with high-dimensional…

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Covariate Regularized Community Detection in Sparse Graphs

稀疏图中协变量正则化的社区发现

In this article, we investigate community detection in networks in the presence of node covariates. In many instances, covariates and networks individually only give a partial view of the cluster structure. One needs to jointly infer the full cluster structure by considering both. In statistics, an emerging body of work has been focused on combining information from both the edges in the network and the node covariates to infer community memberships. However, so far the…

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