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A proximal distance algorithm for likelihood-based sparse covariance estimation

基于似然的稀疏协方差估计:近端距离算法

Summary This paper addresses the task of estimating a covariance matrix under a patternless sparsity assumption. In contrast to existing approaches based on thresholding or shrinkage penalties, we propose a likelihood-based method that regularizes the distance from the covariance estimate to a symmetric sparsity set. This formulation avoids unwanted shrinkage induced by more common norm penalties, and enables optimization of the resulting nonconvex objective by solving a…

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High-dimensional linear regression via implicit regularization

通过隐式正则化进行高维线性回归

Summary Many statistical estimators for high-dimensional linear regression are $M$-estimators, formed through minimizing a data-dependent square loss function plus a regularizer. This work considers a new class of estimators implicitly defined through a discretized gradient dynamic system under overparameterization. We show that, under suitable restricted isometry conditions, overparameterization leads to implicit regularization: if we directly apply gradient descent to the…

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Adjusting the Benjamini–Hochberg method for controlling the false discovery rate in knockoff-assisted variable selection

调整Benjamini–Hochberg方法以控制knockoff变量选择的错误发现率

Summary We consider the knockoff-based multiple testing set-up of Barber & Candès (2015). for variable selection in multiple regression. The method of Benjamini & Hochberg (1995) and an adaptive version of it are adjusted to this set-up, transforming them to valid $p$-value-based, false discovery rate-controlling methods that do not rely on specifying the correlation structure of the explanatory variables. Simulations and real data applications show that the proposed methods…

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Significance testing for canonical correlation analysis in high dimensions

高维典型相关分析的显著性检验

Summary We consider the problem of testing for the presence of linear relationships between large sets of random variables based on a postselection inference approach to canonical correlation analysis. The challenge is to adjust for the selection of subsets of variables having linear combinations with maximal sample correlation. To this end, we construct a stabilized one-step estimator of the Euclidean norm of the canonical correlations maximized over subsets of variables of…

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High-Dimensional Principal Component Analysis with Heterogeneous Missingness

异质缺失下的高维主成分分析

Abstract We study the problem of high-dimensional Principal Component Analysis (PCA) with missing observations. In a simple, homogeneous observation model, we show that an existing observed-proportion weighted (OPW) estimator of the leading principal components can (nearly) attain the minimax optimal rate of convergence, which exhibits an interesting phase transition. However, deeper investigation reveals that, particularly in more realistic settings where the observation…

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Conditional Independence Testing in Hilbert Spaces with Applications to Functional Data Analysis

Hilbert 空间中的条件独立检验及函数型数据应用

Abstract We study the problem of testing the null hypothesis that X and Y are conditionally independent given Z, where each of X, Y and Z may be functional random variables. This generalises testing the significance of X in a regression model of scalar response Y on functional regressors X and Z. We show, however, that even in the idealised setting where additionally (X, Y, Z) has a Gaussian distribution, the power of any test cannot exceed its size. Further modelling…

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CovNet: Covariance Networks for Functional Data on Multidimensional Domains

CovNet:多维定义域函数型数据的协方差网络

Abstract Covariance estimation is ubiquitous in functional data analysis. Yet, the case of functional observations over multidimensional domains introduces computational and statistical challenges, rendering the standard methods effectively inapplicable. To address this problem, we introduce Covariance Networks (CovNet) as a modelling and estimation tool. The CovNet model is universal—it can be used to approximate any covariance up to desired precision. Moreover, the model…

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Dimension-Free Mixing for High-Dimensional Bayesian Variable Selection

高维贝叶斯变量选择中不依赖维度的混合时间

Abstract Yang et al. proved that the symmetric random walk Metropolis–Hastings algorithm for Bayesian variable selection is rapidly mixing under mild high-dimensional assumptions. We propose a novel Markov chain Monte Carlo (MCMC) sampler using an informed proposal scheme, which we prove achieves a much faster mixing time that is independent of the number of covariates, under the assumptions of Yang et al. To the best of our knowledge, this is the first high-dimensional…

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Neuronized Priors for Bayesian Sparse Linear Regression

贝叶斯稀疏线性回归的神经元化先验

Although Bayesian variable selection methods have been intensively studied, their routine use in practice has not caught up with their non-Bayesian counterparts such as Lasso, likely due to difficulties in both computations and flexibilities of prior choices. To ease these challenges, we propose the neuronized priors to unify and extend some popular shrinkage priors, such as Laplace, Cauchy, horseshoe, and spike-and-slab priors. A neuronized prior can be written as the…

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Inference of Breakpoints in High-dimensional Time Series

高维时间序列的断点推断

For multiple change-points detection of high-dimensional time series, we provide asymptotic theory concerning the consistency and the asymptotic distribution of the breakpoint statistics and estimated break sizes. The theory backs up a simple two-step procedure for detecting and estimating multiple change-points. The proposed two-step procedure involves the maximum of a MOSUM (moving sum) type statistics in the first step and a CUSUM (cumulative sum) refinement step on an…

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Individual Data Protected Integrative Regression Analysis of High-Dimensional Heterogeneous Data

保护个体数据的高维异质研究整合回归

Evidence-based decision making often relies on meta-analyzing multiple studies, which enables more precise estimation and investigation of generalizability. Integrative analysis of multiple heterogeneous studies is, however, highly challenging in the ultra high-dimensional setting. The challenge is even more pronounced when the individual-level data cannot be shared across studies, known as DataSHIELD contraint. Under sparse regression models that are assumed to be similar…

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Adaptive Inference for Change Points in High-Dimensional Data

高维数据变点的自适应推断

In this article, we propose a class of test statistics for a change point in the mean of high-dimensional independent data. Our test integrates the U-statistic based approach in a recent work by Wang et al. and the Lq-norm based high-dimensional test in a recent work by He et al., and inherits several appealing features such as being tuning parameter free and asymptotic independence for test statistics corresponding to even q’s. A simple combination of test statistics…

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Linear Hypothesis Testing in Linear Models With High-Dimensional Responses

高维响应线性模型中的线性假设检验

In this paper, we propose a new projection test for linear hypotheses on regression coefficient matrices in linear models with high dimensional responses. We systematically study the theoretical properties of the proposed test. We first derive the optimal projection matrix for any given projection dimension to achieve the best power and provide an upper bound for the optimal dimension of projection matrix. We further provide insights into how to construct the optimal…

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Kernel Ordinary Differential Equations

核常微分方程

Ordinary differential equation (ODE) is widely used in modeling biological and physical processes in science. In this article, we propose a new reproducing kernel-based approach for estimation and inference of ODE given noisy observations. We do not assume the functional forms in ODE to be known, or restrict them to be linear or additive, and we allow pairwise interactions. We perform sparse estimation to select individual functionals, and construct confidence intervals for…

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Testing Mediation Effects Using Logic of Boolean Matrices

利用布尔矩阵逻辑检验中介效应

A central question in high-dimensional mediation analysis is to infer the significance of individual mediators. The main challenge is that the total number of potential paths that go through any mediator is super-exponential in the number of mediators. Most existing mediation inference solutions either explicitly impose that the mediators are conditionally independent given the exposure, or ignore any potential directed paths among the mediators. In this article, we propose…

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Consistent Sparse Deep Learning: Theory and Computation

一致稀疏深度学习:理论与计算

Deep learning has been the engine powering many successes of data science. However, the deep neural network (DNN), as the basic model of deep learning, is often excessively over-parameterized, causing many difficulties in training, prediction and interpretation. We propose a frequentist-like method for learning sparse DNNs and justify its consistency under the Bayesian framework: the proposed method could learn a sparse DNN with at most O(n/ log (n)) connections and nice…

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Variable Selection in the Presence of Factors: A Model Selection Perspective

含分类变量的变量选择:模型选择视角

In the context of a Gaussian multiple regression model, we address the problem of variable selection when in the list of potential predictors there are factors, that is, categorical variables. We adopt a model selection perspective, that is, we approach the problem by constructing a class of models, each corresponding to a particular selection of active variables. The methodology is Bayesian and proceeds by computing the posterior probability of each of these models. We…

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Inference for High-Dimensional Linear Mixed-Effects Models: A Quasi-Likelihood Approach

高维线性混合效应模型的推断:拟似然方法

Linear mixed-effects models are widely used in analyzing clustered or repeated measures data. We propose a quasi-likelihood approach for estimation and inference of the unknown parameters in linear mixed-effects models with high-dimensional fixed effects. The proposed method is applicable to general settings where the dimension of the random effects and the cluster sizes are possibly large. Regarding the fixed effects, we provide rate optimal estimators and valid inference…

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Deep Compositional Spatial Models

深度复合空间模型

Spatial processes with nonstationary and anisotropic covariance structure are often used when modeling, analyzing, and predicting complex environmental phenomena. Such processes may often be expressed as ones that have stationary and isotropic covariance structure on a warped spatial domain. However, the warping function is generally difficult to fit and not constrained to be injective, often resulting in “space-folding.” Here, we propose modeling an injective warping…

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Fast, Optimal, and Targeted Predictions Using Parameterized Decision Analysis

利用参数化决策分析实现快速、最优与目标导向预测

Prediction is critical for decision-making under uncertainty and lends validity to statistical inference. With targeted prediction, the goal is to optimize predictions for specific decision tasks of interest, which we represent via functionals. Although classical decision analysis extracts predictions from a Bayesian model, these predictions are often difficult to interpret and slow to compute. Instead, we design a class of parameterized actions for Bayesian decision…

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Distributed Estimation for Principal Component Analysis: An Enlarged Eigenspace Analysis

主成分分析的分布式估计:扩展特征子空间分析

The growing size of modern datasets brings many challenges to the existing statistical estimation approaches, which calls for new distributed methodologies. This article studies distributed estimation for a fundamental statistical machine learning problem, principal component analysis (PCA). Despite the massive literature on top eigenvector estimation, much less is presented for the top-L-dim (L > 1) eigenspace estimation, especially in a distributed manner. We propose a…

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On the Hauck–Donner Effect in Wald Tests: Detection, Tipping Points, and Parameter Space Characterization

Wald 检验中的 Hauck–Donner 效应:检测、临界点与参数空间刻画

The Wald test remains ubiquitous in statistical practice despite shortcomings such as its inaccuracy in small samples and lack of invariance under reparameterization. This article develops on another but lesser-known shortcoming called the Hauck–Donner effect (HDE) whereby a Wald test statistic is no longer monotone increasing as a function of increasing distance between the parameter estimate and the null value. Resulting in an upward biased p-value and loss of power, the…

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Directed Community Detection With Network Embedding

结合网络嵌入的有向社区检测

Community detection in network data aims at grouping similar nodes sharing certain characteristics together. Most existing methods focus on detecting communities in undirected networks, where similarity between nodes is measured by their node features and whether they are connected. In this article, we propose a novel method to conduct network embedding and community detection simultaneously in a directed network. The network embedding model introduces two sets of vectors to…

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High-Dimensional Model-Assisted Inference for Local Average Treatment Effects With Instrumental Variables

工具变量下局部平均处理效应的高维模型辅助推断

Consider the problem of estimating the local average treatment effect with an instrument variable, where the instrument unconfoundedness holds after adjusting for a set of measured covariates. Several unknown functions of the covariates need to be estimated through regression models, such as instrument propensity score and treatment and outcome regression models. We develop a computationally tractable method in high-dimensional settings where the numbers of regression terms…

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