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On the asymptotic distribution of scrambled net quadrature

扰乱网数值积分的渐近分布

Recently, in a series of articles, Owen proposed the use of scrambled (t.m.s) nets and (t.s) sequences in high-dimensional numerical integration. These scrambled nets and sequences achieve the superior accuracy of equidistribution methods while allowing for the simpler error estimation techniques of Monte Carlo methods. The main aim of this article is to use Stein's method to study the asymptotic distribution of the scrambled (0.m.s) net integral estimate. In particular, it…

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Likelihood ratio of unidentifiable models and multilayer neural networks

不可识别模型与多层神经网络的似然比

This paper discusses the behavior of the maximum likelihood estimator (MLE), in the case that the true parameter cannot be identified uniquely. Among many statistical models with unidentifiability, neural network models are the main concern of this paper. It is known in some models with unidentifiability that the asymptotics of the likelihood ratio of the MLE has an unusually larger order. Using the framework of locally conic models put forth by Dacunha-Castelle and Gassiat…

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Semiparametric Regression for the Area Under the Receiver Operating Characteristic Curve

受试者工作特征曲线下面积的半参数回归

Medical advances continue to provide new and potentially better means for detecting disease. Such is true in cancer, for example, where biomarkers are sought for early detection and where improvements in imaging methods may pick up the initial functional and molecular changes associated with cancer development. In other binary classification tasks, computational algorithms such as neural networks, support vector machines, and evolutionary algorithms have been applied to…

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Detecting Differentially Expressed Genes in Microarrays Using Bayesian Model Selection

利用贝叶斯模型选择识别微阵列中的差异表达基因

DNA microarrays open up a broad new horizon for investigators interested in studying the genetic determinants of disease. The high throughput nature of these arrays, where differential expression for thousands of genes can be measured simultaneously, creates an enormous wealth of information, but also poses a challenge for data analysis because of the large multiple testing problem involved. The solution has generally been to focus on optimizing false-discovery rates while…

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Boosting With the L 2 Loss

采用平方损失的提升方法

This article investigates a computationally simple variant of boosting, L2Boost, which is constructed from a functional gradient descent algorithm with the L2-loss function. Like other boosting algorithms, L2Boost uses many times in an iterative fashion a prechosen fitting method, called the learner. Based on the explicit expression of refitting of residuals of L2Boost, the case with (symmetric) linear learners is studied in detail in both regression and classification. In…

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Classical Model Selection via Simulated Annealing

通过模拟退火进行经典模型选择

Summary The classical approach to statistical analysis is usually based upon finding values for model parameters that maximize the likelihood function. Model choice in this context is often also based on the likelihood function, but with the addition of a penalty term for the number of parameters. Though models may be compared pairwise by using likelihood ratio tests for example, various criteria such as the Akaike information criterion have been proposed as alternatives…

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On the Predictive Distributions of Outcome Gains in the Presence of an Unidentified Parameter

存在未识别参数时的结果增益预测分布

distributions of outcome gains in the framework of a standard latent variable selection model. Although most previous work has focused on estimation of mean treatment parameters as the method for characterizing outcome gains from program participation, we show how the entire distributions associated with these gains can be obtained in certain situations. Although the out-of-sample outcome gain distributions depend on an unidentified parameter, we use the results of Koop and…

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On Additive Conditional Quantiles With High-Dimensional Covariates

高维协变量下的加性条件分位数

We investigate the estimation of the conditional quantile when many covariates are involved. In particular, we model the conditional quantile of a response as a nonlinear additive function of relevant covariates. For this setup, we propose a nonparametric smoother to estimate the unknown functions. The estimator provides direct computation of the nonlinear functions. Because it does not require any iteration, the estimator allows fast and routine data analysis. On the…

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Building Adaptive Estimating Equations When Inverse of Covariance Estimation is Difficult

协方差逆矩阵难以估计时的自适应估计方程

Summary To construct an optimal estimating function by weighting a set of score functions, we must either know or estimate consistently the covariance matrix for the individual scores. In problems with high dimensional correlated data the estimated covariance matrix could be unreliable. The smallest eigenvalues of the covariance matrix will be the most important for weighting the estimating equations, but in high dimensions these will be poorly determined. Generalized…

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Thin Plate Regression Splines

薄板回归样条

Summary I discuss the production of low rank smoothers for d ≥ 1 dimensional data, which can be fitted by regression or penalized regression methods. The smoothers are constructed by a simple transformation and truncation of the basis that arises from the solution of the thin plate spline smoothing problem and are optimal in the sense that the truncation is designed to result in the minimum possible perturbation of the thin plate spline smoothing problem given the dimension…

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Model selection in nonparametric regression

非参数回归中的模型选择

Model selection using a penalized data-splitting device is studied in the context of nonparametric regression. Finite sample bounds under mild conditions are obtained. The resulting estimates are adaptive for large classes of functions.

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Wavelet threshold estimation for additive regression models

加性回归模型的小波阈值估计

Additive regression models have turned out to be useful statistical tools in the analysis of high-dimensional data. The attraction of such models is that the additive component can be estimated with the same optimal convergence rate as a one-dimensional nonparametric regression. However, this optimal property holds only when all the additive components have the same degree of "homogeneous" smoothness. In this paper, we propose a two-step wavelet thresholding estimation…

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An investigation of tests for linearity and the accuracy of likelihood based inference using random fields

随机场方法的线性检验与似然推断准确性考察

We analyze the random field regression model approach recently suggested by Hamilton (2001, Econometrica, 69, 537--73). We show through extensive simulation studies that although the random field approach is indeed very closely related to the non-parametric spline smoother it seems to offer several advantages over the latter. First, tests for neglected nonlinearity based on Hamilton's random field approach seem to be more powerful than existing test statistics developed…

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Parsimonious Covariance Matrix Estimation for Longitudinal Data

纵向数据的简约协方差矩阵估计

This article proposes a data-driven method to identify parsimony in the covariance matrix of longitudinal data and to exploit any such parsimony to produce a statistically efficient estimator of the covariance matrix. The approach parameterizes the covariance matrix through the Cholesky decomposition of its inverse. For longitudinal data, this is a one-step-ahead predictive representation, and the Cholesky factor is likely to have off-diagonal elements that are zero or close…

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Penalized Spline Estimation for Partially Linear Single-Index Models

部分线性单指标模型的惩罚样条估计

Single-index models are potentially important tools for multivariate nonparametric regression. They generalize linear regression by replacing the linear combination α0Tx with a nonparametric component, η0(α0Tx), where η0(·) is an unknown univariate link function. By reducing the dimensionality from that of a general covariate vector x to a univariate index α0Tx, single-index models avoid the so-called “curse of dimensionality.” We propose penalized spline (P-spline)…

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Nearest-Neighbor Variance Estimation (NNVE)

最近邻方差估计(NNVE)

Robust covariance estimation commonly proceeds by downweighting outliers. In this article we measure the “outlyingness” of a data point by the standardized distance between the point and its Kth nearest neighbor. The appropriate weights for robust estimation are found by a model-based mixture modeling approach that follows from considering the data cloud as a realization of a high-dimensional point process. To correct a potential bias when there are no outliers, we introduce…

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Predictive Variable Selection in Generalized Linear Models

广义线性模型中的预测式变量选择

Here we extend predictive method for model selection of Laud and Ibrahim to the generalized linear model. This prescription avoids the need to directly specify prior probabilities of models and prior densities for the parameters. Instead, a prior prediction for the response induces the required priors. We propose normal and conjugate priors for generalized linear models, each using a single prior prediction for the mean response to induce suitable priors for each…

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Markov Chain Marginal Bootstrap

马尔可夫链边际自助法

Markov chain marginal bootstrap (MCMB) is a new method for constructing confidence intervals or regions for maximum likelihood estimators of certain parametric models and for a wide class of M estimators of linear regression. The MCMB method distinguishes itself from the usual bootstrap methods in two important aspects: it involves solving only one-dimensional equations for parameters of any dimension and produces a Markov chain rather than a (conditionally) independent…

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Bayes Model Averaging with Selection of Regressors

结合回归变量选择的贝叶斯模型平均

Summary When a number of distinct models contend for use in prediction, the choice of a single model can offer rather unstable predictions. In regression, stochastic search variable selection with Bayesian model averaging offers a cure for this robustness issue but at the expense of requiring very many predictors. Here we look at Bayes model averaging incorporating variable selection for prediction. This offers similar mean-square errors of prediction but with a vastly…

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An Adaptive Estimation of Dimension Reduction Space

降维空间的自适应估计

Summary Searching for an effective dimension reduction space is an important problem in regression, especially for high dimensional data. We propose an adaptive approach based on semiparametric models, which we call the (conditional) minimum average variance estimation (MAVE) method, within quite a general setting. The MAVE method has the following advantages. Most existing methods must undersmooth the nonparametric link function estimator to achieve a faster rate of…

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Influence Diagnostics and Outlier Tests for Semiparametric Mixed Models

半参数混合模型的影响诊断与异常值检验

Summary Semiparametric mixed models are useful in biometric and econometric applications, especially for longitudinal data. Maximum penalized likelihood estimators (MPLEs) have been shown to work well by Zhang and co-workers for both linear coefficients and nonparametric functions. This paper considers the role of influence diagnostics in the MPLE by extending the case deletion and subject deletion analysis of linear models to accommodate the inclusion of a nonparametric…

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Vines--a new graphical model for dependent random variables

Vine:依赖随机变量的一种新图模型

A new graphical model, called a vine, for dependent random variables is introduced. Vines generalize the Markov trees often used in modelling high-dimensional distributions. They differ from Markov trees and Bayesian belief nets in that the concept of conditional independence is weakened to allow for various forms of conditional dependence. Vines can be used to specify multivariate distributions in a straightforward way by specifying various marginal distributions and the…

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