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On the Properties of the Synthetic Control Estimator with Many Periods and Many Controls

大量时期与大量对照单位下合成控制估计量的性质

We consider the asymptotic properties of the synthetic control (SC) estimator when both the number of pretreatment periods and control units are large. If potential outcomes follow a linear factor model, we provide conditions under which the SC unit asymptotically recovers the factor structure of the treated unit, even when the pretreatment fit is imperfect. This happens when there are weights diluted among an increasing number of control units such that a weighted average…

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The Augmented Synthetic Control Method

增广合成控制法

The synthetic control method (SCM) is a popular approach for estimating the impact of a treatment on a single unit in panel data settings. The “synthetic control” is a weighted average of control units that balances the treated unit’s pretreatment outcomes and other covariates as closely as possible. A critical feature of the original proposal is to use SCM only when the fit on pretreatment outcomes is excellent. We propose Augmented SCM as an extension of SCM to settings…

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On Robustness of Principal Component Regression

主成分回归的稳健性

Principal component regression (PCR) is a simple, but powerful and ubiquitously utilized method. Its effectiveness is well established when the covariates exhibit low-rank structure. However, its ability to handle settings with noisy, missing, and mixed-valued, that is, discrete and continuous, covariates is not understood and remains an important open challenge. As the main contribution of this work, we establish the robustness of PCR, without any change, in this respect…

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An Exact and Robust Conformal Inference Method for Counterfactual and Synthetic Controls

反事实与合成控制的精确稳健共形推断方法

We introduce new inference procedures for counterfactual and synthetic control methods for policy evaluation. We recast the causal inference problem as a counterfactual prediction and a structural breaks testing problem. This allows us to exploit insights from conformal prediction and structural breaks testing to develop permutation inference procedures that accommodate modern high-dimensional estimators, are valid under weak and easy-to-verify conditions, and are provably…

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Matrix Completion Methods for Causal Panel Data Models

因果面板数据模型的矩阵补全方法

In this paper we study methods for estimating causal effects in settings with panel data, where some units are exposed to a treatment during some periods and the goal is estimating counterfactual (untreated) outcomes for the treated unit/period combinations. We propose a class of matrix completion estimators that uses the observed elements of the matrix of control outcomes corresponding to untreated unit/periods to impute the "missing" elements of the control outcome matrix,…

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A Bayesian Hierarchical CACE Model Accounting for Incomplete Noncompliance With Application to a Meta-analysis of Epidural Analgesia on Cesarean Section

处理不完整依从信息的贝叶斯分层 CACE 模型:硬膜外镇痛与剖宫产的荟萃分析

Noncompliance with assigned treatments is a common challenge in analyzing and interpreting randomized clinical trials (RCTs). One way to handle noncompliance is to estimate the complier-average causal effect (CACE), the intervention's efficacy in the subpopulation that complies with assigned treatment. In a two-step meta-analysis, one could first estimate CACE for each study, then combine them to estimate the population-averaged CACE. However, when some trials do not report…

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Forecasting Unemployment Using Internet Search Data via PRISM

利用互联网搜索数据与 PRISM 预测失业保险初次申请人数

Big data generated from the Internet offer great potential for predictive analysis. Here we focus on using online users’ Internet search data to forecast unemployment initial claims weeks into the future, which provides timely insights into the direction of the economy. To this end, we present a novel method Penalized Regression with Inferred Seasonality Module (PRISM), which uses publicly available online search data from Google. PRISM is a semiparametric method, motivated…

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A Semiparametric Kernel Independence Test With Application to Mutational Signatures

半参数核独立性检验及其突变特征应用

Cancers arise owing to somatic mutations, and the characteristic combinations of somatic mutations form mutational signatures. Despite many mutational signatures being identified, mutational processes underlying a number of mutational signatures remain unknown, which hinders the identification of interventions that may reduce somatic mutation burdens and prevent the development of cancer. We demonstrate that the unknown cause of a mutational signature can be inferred by the…

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A Bayesian State-Space Approach to Mapping Directional Brain Networks

刻画有向脑网络的贝叶斯状态空间方法

The human brain is a directional network system of brain regions involving directional connectivity. Seizures are a directional network phenomenon as abnormal neuronal activities start from a seizure onset zone (SOZ) and propagate to otherwise healthy regions. To localize the SOZ of an epileptic patient, clinicians use intracranial electroencephalography (iEEG) to record the patient’s intracranial brain activity in many small regions. iEEG data are high-dimensional…

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Biased Encouragements and Heterogeneous Effects in an Instrumental Variable Study of Emergency General Surgical Outcomes

急诊普外科结局工具变量研究中的偏倚鼓励与异质性效应

We investigate the efficacy of surgical versus nonsurgical management for two gastrointestinal conditions, colitis and diverticulitis, using observational data. We deploy an instrumental variable design with surgeons’ tendencies to operate as an instrument. Assuming instrument validity, we find that nonsurgical alternatives can reduce both hospital length of stay and the risk of complications, with estimated effects larger for septic patients than for nonseptic patients. The…

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IFAA: Robust Association Identification and Inference for Absolute Abundance in Microbiome Analyses

IFAA:微生物组绝对丰度的稳健关联识别与推断

The target of inference in microbiome analyses is usually relative abundance (RA) because RA in a sample (e.g., stool) can be considered as an approximation of RA in an entire ecosystem (e.g., gut). However, inference on RA suffers from the fact that RA are calculated by dividing absolute abundances (AAs) over the common denominator (CD), the summation of all AA (i.e., library size). Because of that, perturbation in one taxon will result in a change in the CD and thus cause…

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A New Coefficient of Correlation

一种新的相关系数

–Is it possible to define a coefficient of correlation which is (a) as simple as the classical coefficients like Pearson’s correlation or Spearman’s correlation, and yet (b) consistently estimates some simple and interpretable measure of the degree of dependence between the variables, which is 0 if and only if the variables are independent and 1 if and only if one is a measurable function of the other, and (c) has a simple asymptotic theory under the hypothesis of…

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Sparse Learning and Structure Identification for Ultrahigh-Dimensional Image-on-Scalar Regression

超高维图像对标量回归中的稀疏学习与结构识别

This article considers high-dimensional image-on-scalar regression, where the spatial heterogeneity of covariate effects on imaging responses is investigated via a flexible partially linear spatially varying coefficient model. To tackle the challenges of spatial smoothing over the imaging response’s complex domain consisting of regions of interest, we approximate the spatially varying coefficient functions via bivariate spline functions over triangulation. We first study…

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Smooth Backfitting of Proportional Hazards With Multiplicative Components

具有乘法分量的比例风险模型的光滑回代估计

Smooth backfitting has proven to have a number of theoretical and practical advantages in structured regression. By projecting the data down onto the structured space of interest smooth backfitting provides a direct link between data and estimator. This article introduces the ideas of smooth backfitting to survival analysis in a proportional hazard model, where we assume an underlying conditional hazard with multiplicative components. We develop asymptotic theory for the…

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Integrating Multisource Block-Wise Missing Data in Model Selection

模型选择中多来源分块缺失数据的整合

For multisource data, blocks of variable information from certain sources are likely missing. Existing methods for handling missing data do not take structures of block-wise missing data into consideration. In this article, we propose a multiple block-wise imputation (MBI) approach, which incorporates imputations based on both complete and incomplete observations. Specifically, for a given missing pattern group, the imputations in MBI incorporate more samples from groups…

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Bayesian Projected Calibration of Computer Models

计算机模型的贝叶斯投影校准

We develop a Bayesian approach called the Bayesian projected calibration to address the problem of calibrating an imperfect computer model using observational data from an unknown complex physical system. The calibration parameter and the physical system are parameterized in an identifiable fashion via the L2-projection. The physical system is imposed a Gaussian process prior distribution, which naturally induces a prior distribution on the calibration parameter through the…

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Spherical Regression Under Mismatch Corruption With Application to Automated Knowledge Translation

配对错配污染下的球面回归及自动知识转换应用

Motivated by a series of applications in data integration, language translation, bioinformatics, and computer vision, we consider spherical regression with two sets of unit-length vectors when the data are corrupted by a small fraction of mismatch in the response-predictor pairs. We propose a three-step algorithm in which we initialize the parameters by solving an orthogonal Procrustes problem to estimate a translation matrix W ignoring the mismatch. We then estimate a…

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Discussion of “Text Selection” by Bryan Kelly, Asaf Manela, and Alan Moreira

关于 Kelly、Manela 与 Moreira《文本选择》的讨论

The article addresses the important question of how to infer information from text data, which is a high-dimensional form of data. The article proposes to estimate separately the probability of sel...

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Text Selection

文本选择

Text data is ultra-high dimensional, which makes machine learning techniques indispensable for textual analysis. Text is often selected—journalists, speechwriters, and others craft messages to target their audiences’ limited attention. We develop an economically motivated high-dimensional selection model that improves learning from text (and from sparse counts data more generally). Our model is especially useful when the choice to include a phrase is more interesting than…

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Price Dividend Ratio and Long-Run Stock Returns: A Score-Driven State Space Model

价格股利比与长期股票收益:得分驱动的状态空间模型

Abstract–In this article, we develop a general framework to analyze state space models with time-varying system matrices, where time variation is driven by the score of the conditional likelihood. We derive a new filter that allows for the simultaneous estimation of the state vector and of the time-varying matrices. We use this method to study the time-varying relationship between the price dividend ratio, expected stock returns and expected dividend growth in the United…

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Closed-Form Multi-Factor Copula Models With Observation-Driven Dynamic Factor Loadings

具有观测驱动动态因子载荷的闭式多因子 Copula 模型

We develop new multi-factor dynamic copula models with time-varying factor loadings and observation-driven dynamics. The new models are highly flexible, scalable to high dimensions, and ensure positivity of covariance and correlation matrices. A closed-form likelihood expression allows for straightforward parameter estimation and likelihood inference. We apply the new model to a large panel of 100 U.S. stocks over the period 2001–2014. The proposed multi-factor structure is…

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Inference in Additively Separable Models With a High-Dimensional Set of Conditioning Variables

高维条件变量下加性可分模型的推断

This article studies nonparametric series estimation and inference for the effect of a single variable of interest x on an outcome y in the presence of potentially high-dimensional conditioning variables z. The context is an additively separable model E[y|x,z]=g0(x)+h0(z). The model is high-dimensional in the sense that the series of approximating functions for h0(z) can have more terms than the sample size, thereby allowing z potentially to have very many measured…

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A Framework for Eliciting, Incorporating, and Disciplining Identification Beliefs in Linear Models

在线性模型中引出、纳入并约束识别信念的框架

To estimate causal effects from observational data, an applied researcher must impose beliefs. The instrumental variables exclusion restriction, for example, represents the belief that the instrument has no direct effect on the outcome of interest. Yet beliefs about instrument validity do not exist in isolation. Applied researchers often discuss the likely direction of selection and the potential for measurement error in their articles but lack formal tools for incorporating…

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Generalized Jump Regressions for Local Moments

局部矩的广义跳跃回归

We develop new high-frequency-based inference procedures for analyzing the relationship between jumps in instantaneous moments of stochastic processes. The estimation consists of two steps: the nonparametric determination of the jumps as differences in local averages, followed by a minimum-distance type estimation of the parameters of interest under general loss functions that include both least-square and more robust quantile regressions as special cases. The resulting…

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