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High-Dimensional Spatial Quantile Function-on-Scalar Regression

高维空间分位数函数对标量回归

This article develops a novel spatial quantile function-on-scalar regression model, which studies the conditional spatial distribution of a high-dimensional functional response given scalar predictors. With the strength of both quantile regression and copula modeling, we are able to explicitly characterize the conditional distribution of the functional or image response on the whole spatial domain. Our method provides a comprehensive understanding of the effect of scalar…

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Nonparametric Tests of the Causal Null With Nondiscrete Exposures

非离散暴露下因果零假设的非参数检验

In many scientific studies, it is of interest to determine whether an exposure has a causal effect on an outcome. In observational studies, this is a challenging task due to the presence of confounding variables that affect both the exposure and the outcome. Many methods have been developed to test for the presence of a causal effect when all such confounding variables are observed and when the exposure of interest is discrete. In this article, we propose a class of…

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Survival Regression Models With Dependent Bayesian Nonparametric Priors

具有相依贝叶斯非参数先验的生存回归模型

We present a novel Bayesian nonparametric model for regression in survival analysis. Our model builds on the classical neutral to the right model of Doksum and on the Cox proportional hazards model of Kim and Lee. The use of a vector of dependent Bayesian nonparametric priors allows us to efficiently model the hazard as a function of covariates while allowing nonproportionality. The model can be seen as having competing latent risks. We characterize the posterior of the…

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Minimax Efficient Random Experimental Design Strategies With Application to Model-Robust Design for Prediction

极小极大高效随机实验设计及其模型稳健预测应用

In game theory and statistical decision theory, a random (i.e., mixed) decision strategy often outperforms a deterministic strategy in minimax expected loss. As experimental design can be viewed as a game pitting the Statistician against Nature, the use of a random strategy to choose a design will often be beneficial. However, the topic of minimax-efficient random strategies for design selection is mostly unexplored, with consideration limited to Fisherian randomization of…

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Sensitivity Analysis via the Proportion of Unmeasured Confounding

基于未测量混杂比例的敏感性分析

In observational studies, identification of ATEs is generally achieved by assuming that the correct set of confounders has been measured and properly included in the relevant models. Because this assumption is both strong and untestable, a sensitivity analysis should be performed. Common approaches include modeling the bias directly or varying the propensity scores to probe the effects of a potential unmeasured confounder. In this article, we take a novel approach whereby…

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Estimating Malaria Vaccine Efficacy in the Absence of a Gold Standard Case Definition: Mendelian Factorial Design

无金标准病例定义下的疟疾疫苗效力估计:孟德尔析因设计

Accurate estimates of malaria vaccine efficacy require a reliable definition of a malaria case. However, the symptoms of clinical malaria are unspecific, overlapping with other childhood illnesses. Additionally, children in endemic areas tolerate varying levels of parasitemia without symptoms. Together, this makes finding a gold-standard case definition challenging. We present a method to identify and estimate malaria vaccine efficacy that does not require an observable…

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Multicategory Angle-Based Learning for Estimating Optimal Dynamic Treatment Regimes With Censored Data

利用多类别角度学习估计删失数据下的最优动态治疗方案

An optimal dynamic treatment regime (DTR) consists of a sequence of decision rules in maximizing long-term benefits, which is applicable for chronic diseases such as HIV infection or cancer. In this article, we develop a novel angle-based approach to search the optimal DTR under a multicategory treatment framework for survival data. The proposed method targets to maximize the conditional survival function of patients following a DTR. In contrast to most existing approaches…

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Semiparametric Inference for Nonmonotone Missing-Not-at-Random Data: The No Self-Censoring Model

非单调非随机缺失数据的半参数推断:无自我删失模型

We study the identification and estimation of statistical functionals of multivariate data missing non-monotonically and not-at-random, taking a semiparametric approach. Specifically, we assume that the missingness mechanism satisfies what has been previously called "no self-censoring" or "itemwise conditionally independent nonresponse," which roughly corresponds to the assumption that no partially-observed variable directly determines its own missingness status. We show…

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LAWS: A Locally Adaptive Weighting and Screening Approach to Spatial Multiple Testing

LAWS:空间多重检验的局部自适应加权与筛选方法

Exploiting spatial patterns in large-scale multiple testing promises to improve both power and interpretability of false discovery rate (FDR) analyses. This article develops a new class of locally adaptive weighting and screening (LAWS) rules that directly incorporates useful local patterns into inference. The idea involves constructing robust and structure-adaptive weights according to the estimated local sparsity levels. LAWS provides a unified framework for a broad range…

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Multiscale Quantile Segmentation

多尺度分位数分段

We introduce a new methodology for analyzing serial data by quantile regression assuming that the underlying quantile function consists of constant segments. The procedure does not rely on any distributional assumption besides serial independence. It is based on a multiscale statistic, which allows to control the (finite sample) probability for selecting the correct number of segments S at a given error level, which serves as a tuning parameter. For a proper choice of this…

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High-Dimensional Vector Autoregressive Time Series Modeling via Tensor Decomposition

基于张量分解的高维向量自回归时间序列建模

The classical vector autoregressive model is a fundamental tool for multivariate time series analysis. However, it involves too many parameters when the number of time series and lag order are even moderately large. This article proposes to rearrange the transition matrices of the model into a tensor form such that the parameter space can be restricted along three directions simultaneously via tensor decomposition. In contrast, the reduced-rank regression method can restrict…

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Functional Sequential Treatment Allocation

以分布泛函为目标的序贯处理分配

Consider a setting in which a policy maker assigns subjects to treatments, observing each outcome before the next subject arrives. Initially, it is unknown which treatment is best, but the sequential nature of the problem permits learning about the effectiveness of the treatments. While the multi-armed-bandit literature has shed much light on the situation when the policy maker compares the effectiveness of the treatments through their mean, much less is known about other…

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Predicting the Number of Future Events

未来事件数量的预测

This article describes prediction methods for the number of future events from a population of units associated with an on-going time-to-event process. Examples include the prediction of warranty returns and the prediction of the number of future product failures that could cause serious threats to property or life. Important decisions such as whether a product recall should be mandated are often based on such predictions. Data, generally right-censored (and sometimes left…

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Gaining Outlier Resistance With Progressive Quantiles: Fast Algorithms and Theoretical Studies

利用渐进分位数增强离群值抵抗力:快速算法与理论研究

Outliers widely occur in big-data applications and may severely affect statistical estimation and inference. In this article, a framework of outlier-resistant estimation is introduced to robustify an arbitrarily given loss function. It has a close connection to the method of trimming and includes explicit outlyingness parameters for all samples, which in turn facilitates computation, theory, and parameter tuning. To tackle the issues of nonconvexity and nonsmoothness, we…

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Regression Analysis of Asynchronous Longitudinal Functional and Scalar Data

异步纵向函数型与标量数据的回归分析

Many modern large-scale longitudinal neuroimaging studies, such as the Alzheimer’s Disease Neuroimaging Initiative (ADNI) study, have collected/are collecting asynchronous scalar and functional variables that are measured at distinct time points. The analyses of temporally asynchronous functional and scalar variables pose major technical challenges to many existing statistical approaches. We propose a class of generalized functional partial-linear varying-coefficient models…

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Standard Synthetic Control Methods: The Case of Using All Preintervention Outcomes Together With Covariates

标准合成控制:同时使用全部干预前结果与协变量的情形

It is becoming increasingly popular in applications of standard synthetic control methods to include the entire pretreatment path of the outcome variable as economic predictors. We demonstrate both theoretically and empirically that using all outcome lags as separate predictors renders all other covariates irrelevant in such settings. This finding holds irrespective of how important these covariates are for accurately predicting posttreatment values of the outcome,…

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Realized Quantiles *

已实现分位数

This article proposes a simple approach to estimate quantiles of daily financial returns directly from high-frequency data. We denote the resulting estimator as realized quantile (RQ) and use it to forecast tail risk measures, such as Value at Risk (VaR) and Expected Shortfall (ES). The RQ estimator is built on the assumption that financial logarithm prices are subordinated self-similar processes in intrinsic time. The intrinsic time dimension stochastically transforms the…

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A Structural Model of Homophily and Clustering in Social Networks

社交网络中同质性与聚类的结构模型

I develop and estimate a structural model of network formation with heterogeneous players and latent community structure, whose equilibrium homophily and clustering levels match those usually observed in real-world social networks. Players belong to communities unobserved by the econometrician and have community-specific payoffs, allowing preferences to have a bias for similar people. Players meet sequentially and decide whether to form bilateral links, after receiving a…

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Quasi-Bayesian Inference for Production Frontiers

生产前沿的准贝叶斯推断

This article proposes to estimate and infer the production frontier by combining multiple first-stage extreme quantile estimates via the quasi-Bayesian method. We show the asymptotic properties of the proposed estimator and the validity of the inference procedure. The finite sample performance of our method is illustrated through simulations and an empirical application.

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Synthetic Control Estimation Beyond Comparative Case Studies: Does the Minimum Wage Reduce Employment?

超越比较案例研究的合成控制估计:最低工资是否减少就业?

Panel data are often used in empirical work to account for fixed additive time and unit effects. The synthetic control estimator relaxes the assumption of additive fixed effects for comparative case studies in which a treated unit adopts a single policy. This article generalizes the synthetic control estimator to estimate parameters associated with multiple discrete or continuous explanatory variables, jointly estimating the parameters and synthetic controls for each unit. I…

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State-Varying Factor Models of Large Dimensions

高维状态依赖因子模型

This article develops an inferential theory for state-varying factor models of large dimensions. Unlike constant factor models, loadings are general functions of some recurrent state process. We develop an estimator for the latent factors and state-varying loadings under a large cross-section and time dimension. Our estimator combines nonparametric methods with principal component analysis. We derive the rate of convergence and limiting normal distribution for the factors,…

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Local Polynomial Order in Regression Discontinuity Designs

断点回归设计中的局部多项式阶数选择

Treatment effect estimates in regression discontinuity (RD) designs are often sensitive to the choice of bandwidth and polynomial order, the two important ingredients of widely used local regression methods. While Imbens and Kalyanaraman and Calonico, Cattaneo, and Titiunik provided guidance on bandwidth, the sensitivity to polynomial order still poses a conundrum to RD practitioners. It is understood in the econometric literature that applying the argument of bias reduction…

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Imputations for High Missing Rate Data in Covariates Via Semi-supervised Learning Approach

利用半监督学习插补高缺失率协变量

Advancements in data collection techniques and the heterogeneity of data resources can yield high percentages of missing observations on variables, such as block-wise missing data. Under missing-data scenarios, traditional methods such as the simple average, k-nearest neighbor, multiple, and regression imputations may lead to results that are unstable or unable be computed. Motivated by the concept of semi-supervised learning, we propose a novel approach with which to fill…

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High-Dimensional Interaction Detection With False Sign Rate Control

控制错误符号率的高维交互项筛选

Identifying interaction effects is fundamentally important in many scientific discoveries and contemporary applications, but it is challenging since the number of pairwise interactions increases quadratically with the number of covariates and that of higher-order interactions grows even faster. Although there is a growing literature on interaction detection, little work has been done on the prediction and false sign rate on interaction detection in ultrahigh-dimensional…

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