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利用纵向健康信息学数据对复发事件进行全局与发作特异性预测AI 解读

Accurate prediction of recurrent clinical events is crucial for effective management of chronic conditions such as cancer and cardiovascular disease. In recent years, longitudinal health informatics databases, which routinely collect data on repeated clinical events, have been increasingly utilized to construct risk prediction models. We introduce a novel nonparametric framework to predict recurrent events on a gap time scale using survival tree ensembles. Our framework…

多重异质结果下基因组数据的因果推断AI 解读

With the evolution of single-cell RNA sequencing techniques into a standard approach in genomics, it has become possible to conduct cohort-level causal inferences based on single-cell-level measurements. However, the individual gene expression levels of interest are not directly observable; instead, only repeated proxy measurements from each individual's cells are available, providing a derived outcome to estimate the underlying outcome for each of many genes. In this paper,…

通过自归一化检验函数型参数假设AI 解读

Testing simple or composite hypothesis on a functional parameter has attracted considerable attention in time series analysis. To accommodate for the unknown temporal dependence, classical nonparametric approaches such as block bootstrapping and subsampling all involve a bandwidth parameter, the choice of which can substantially affect the finite sample performance. The self normalization (SN) method is tuning parameter free when applied to the inference of a…

贝叶斯后验分析设计的低成本方法AI 解读

To design Bayesian studies, criteria for the operating characteristics of posterior analyses – such as power and the type I error rate – are often assessed by estimating sampling distributions of posterior probabilities via simulation. In this paper, we propose an economical method to determine optimal sample sizes and decision criteria for such studies. Using our theoretical results that model posterior probabilities as a function of the sample size, we assess operating…

高维卷积秩回归的统计推断AI 解读

High-dimensional penalized rank regression is a powerful tool for modeling high-dimensional data due to its robustness and estimation efficiency. However, the non-smoothness of the rank loss brings great challenges to the computation. To solve this critical issue, high-dimensional convoluted rank regression has been recently proposed, introducing penalized convoluted rank regression estimators. However, these developed estimators cannot be directly used to make inference. In…

从自动建模视角估计过参数化模型AI 解读

From a model-building perspective, we propose a paradigm shift for fitting over-parameterized models. Philosophically, the mindset is to fit models to future observations rather than to the observed sample. Technically, given an imputation method to generate future observations, we fit over-parameterized models to these future observations by optimizing an approximation of the desired expected loss function based on its sample counterpart and an adaptive duality function.…

大型向量自回归模型中的网络格兰杰因果关系发现AI 解读

This article proposes novel inferential procedures for discovering the network Granger causality in highdimensional vector autoregressive models.In particular, we mainly offer two multiple testing procedures designed to control the false discovery rate (FDR).The first procedure is based on the limiting normal distribution of the t-statistics with the debiased lasso estimator.The second procedure is its bootstrap version.We also provide a robustification of the first…

利用高维部分线性半参数混合效应模型比较纵向轨迹AI 解读

In longitudinal research, it is essential to compare sets of trajectories, commonly seen as changes over time in different treatment or patient groups. This paper presents a partial linear semiparametric mixed-effects model (PLSMM) for the analysis and comparison of nonlinear longitudinal trajectories with high-dimensional covariates across groups. Our flexible modeling framework can effectively handle complex temporal effects and extensive data while providing statistical…

再生核希尔伯特空间上的非参数期望短缺回归估计与推断AI 解读

Expected shortfall (ES) has emerged as an important metric for characterizing the tail behavior of a random outcome, specifically associated with rarer events that entail severe consequences. In climate science, the threats of flooding and heatwaves loom large, impacting natural environments and human communities. In actuarial studies, a key observation in modeling insurance claim sizes is that features exhibit distinct effects in explaining small and large claims. This…

基于样本协方差矩阵的完全随机缺失检验AI 解读

We study the problem of testing whether the missing values of a potentially high-dimensional dataset are Missing Completely at Random (MCAR). We relax the problem of testing MCAR to the problem of testing the compatibility of a collection of covariance matrices, motivated by the fact that this procedure is feasible when the dimension grows with the sample size. Our first contributions are to define a natural measure of the incompatibility of a collection of correlation…

海量数据线性分类的多分辨率子抽样AI 解读

Abstract Subsampling is one of the popular methods to balance statistical efficiency and computational efficiency in the big data era. Most approaches aim to select informative or representative sample points to achieve good overall information of the full data. The present work takes the view that sampling techniques are recommended for the region we focus on and summary measures are enough to collect the information for the rest according to a well-designed data…

通过下注构造序贯蒙特卡洛检验AI 解读

Abstract In a Monte Carlo test, the observed dataset is fixed, and several resampled or permuted versions of the dataset are generated in order to test a null hypothesis that the original dataset is exchangeable with the resampled/permuted ones. Sequential Monte Carlo tests aim to save computational resources by generating these additional datasets sequentially one by one and potentially stopping early. While earlier tests yield valid inference at a particular prespecified…

半参数后验修正AI 解读

Abstract We present a new approach to semiparametric inference using corrected posterior distributions. The method allows us to leverage the adaptivity, regularization, and predictive power of nonparametric Bayesian procedures to estimate low-dimensional functionals of interest without being restricted by the holistic Bayesian formalism. Starting from a conventional posterior on the whole data-generating distribution, we correct the marginal posterior for each functional of…

二元结果随机实验精确置信区间的快速计算AI 解读

Given a randomized experiment with binary outcomes, exact confidence intervals for the average causal effect of the treatment can be computed through a series of permutation tests. This approach requires minimal assumptions and is valid for all sample sizes, as it does not rely on large-sample approximations such as those implied by the central limit theorem. We show that these confidence intervals can be found in O(nlogn) permutation tests in the case of balanced designs,…

面板数据政策评价方法的预测区间AI 解读

ABSTRACT We consider the inference on individual and time specific treatment effects on the treated within the framework of panel data approach for programme evaluation. We formulate the target problem as constructing prediction intervals for high‐dimensional linear regressions with weakly dependent data. Post‐LASSO OLS is used for estimation, while dependent wild bootstrap and simple residual bootstrap are used for the construction of prediction intervals. The proposed…

低秩随机矩阵特征向量的逐元素高阶分析：偏差校正、Edgeworth 展开与自助法AI 解读

Understanding the distributions of spectral estimators in low-rank random matrix models, also known as signal-plus-noise matrix models, is fundamentally important in various statistical learning problems, including network analysis, matrix denoising and matrix completion. This paper investigates the entrywise eigenvector distributions in a broad range of low-rank signal-plus-noise matrix models by establishing their higher-order accurate stochastic expansions. At a high…

动态二元选择面板数据模型的半参数估计AI 解读

We propose a new approach to the semiparametric analysis of panel data binary choice models with fixed effects and dynamics (lagged dependent variables). The model under consideration has the same random utility framework as in Honoré and Kyriazidou (2000, Econometrica 68, 839–874). We demonstrate that, with additional serial dependence conditions on the process of deterministic utility and tail restrictions on the error distribution, the (point) identification of the model…

因果中介分析：选择与渐近有效推断AI 解读

Abstract Researchers are often interested in learning not only the effect of treatments on outcomes, but also the mechanisms that transmit these effects. A mediator is a variable that is affected by treatment and subsequently affects outcome. Existing methods for penalized mediation analyses may lead to ignoring important mediators and either assume that finite-dimensional linear models are sufficient to remove confounding bias, or perform no confounding control at all. In…

高维惩罚回归中具有高阶精度的对称 Bootstrap 置信区间AI 解读

This article develops methodology for higher order accurate two-sided Bootstrap confidence intervals (CIs) in high dimensional penalized regression models using the Bootstrap. We consider a large class of penalized regression methods that satisfy the Oracle property of Fan and Li and a stronger variant of it, called the Strong Oracle property. While second order accuracy of the Bootstrap is known for both classes, it is typically not sufficient to guarantee better accuracy…

复杂区域上分位数空间变系数模型的估计与推断AI 解读

This article presents a flexible quantile spatially varying coefficient model (QSVCM) for the regression analysis of spatial data. The proposed model enables researchers to assess the dependence of conditional quantiles of the response variable on covariates while accounting for spatial nonstationarity. Our approach facilitates learning and interpreting heterogeneity in spatial data distributed over complex or irregular domains. We introduce a quantile regression method that…

高维谱密度矩阵的统计推断AI 解读

The spectral density matrix is a fundamental object of interest in time series analysis, and it encodes both contemporary and dynamic linear relationships between component processes of the multivariate system. In this paper we develop novel inference procedures for the spectral density matrix in the high-dimensional setting. Specifically, we introduce a new global testing procedure to test the nullity of the cross-spectral density for a given set of frequencies and across…

时间序列数据的高维 Knockoffs 推断AI 解读

We make some initial attempt to establish the theoretical and methodological foundation for the model-X knockoffs inference for time series data. We suggest the method of time series knockoffs inference (TSKI) by exploiting the ideas of subsampling and e-values to address the difficulty caused by the serial dependence. We also generalize the robust knockoffs inference in Barber, Candès, and Samworth to the time series setting to relax the assumption of known covariate…

隐私化数据的基于模拟的有限样本推断AI 解读

Privacy protection methods, such as differentially private mechanisms, introduce noise into resulting statistics which often produces complex and intractable sampling distributions. In this article, we propose a simulation-based “repro sample” approach to produce statistically valid confidence intervals and hypothesis tests, which builds on the work of Xie and Wang. We show that this methodology is applicable to a wide variety of private inference problems, appropriately…

高维部分线性测量误差模型的校准均衡估计与双重选择AI 解读

In practice, measurement error data is frequently encountered and needs to be handled appropriately. As a result of additional bias induced by measurement error, many existing estimation methods fail to achieve satisfactory performances. This paper studies high-dimensional partially linear measurement error models. It proposes a calibrated equilibrium (CARE) estimation method to calibrate the bias caused by measurement error and overcomes the technical difficulty of the…