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Efficient Empirical Bayes Variable Selection and Estimation in Linear Models

线性模型中的高效经验贝叶斯变量选择与估计

We propose an empirical Bayes method for variable selection and coefficient estimation in linear regression models. The method is based on a particular hierarchical Bayes formulation, and the empirical Bayes estimator is shown to be closely related to the LASSO estimator. Such a connection allows us to take advantage of the recently developed quick LASSO algorithm to compute the empirical Bayes estimate, and provides a new way to select the tuning parameter in the LASSO…

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Combining Linear Regression Models

线性回归模型的组合

Model-combining (i.e., mixing) methods have been proposed in recent years to deal with uncertainty in model selection. Even though advantages of model combining over model selection have been demonstrated in simulations and data examples, it is still unclear to a large extent when model combining should be preferred. In this work, first we propose an instability measure to capture the uncertainty of model selection in estimation, called perturbation instability in estimation…

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On Consistency of Nonparametric Normal Mixtures for Bayesian Density Estimation

贝叶斯密度估计中非参数正态混合的一致性

The past decade has seen a remarkable development in the area of Bayesian nonparametric inference from both theoretical and applied perspectives. As for the latter, the celebrated Dirichlet process has been successfully exploited within Bayesian mixture models, leading to many interesting applications. As for the former, some new discrete nonparametric priors have been recently proposed in the literature that have natural use as alternatives to the Dirichlet process in a…

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A Generalized Wang–Landau Algorithm for Monte Carlo Computation

用于蒙特卡洛计算的广义 Wang–Landau 算法

Inference for a complex system with a rough energy landscape is a central topic in Monte Carlo computation. Motivated by the successes of the Wang–Landau algorithm in discrete systems, we generalize the algorithm to continuous systems. The generalized algorithm has some features that conventional Monte Carlo algorithms do not have. First, it provides a new method for Monte Carlo integration based on stochastic approximation; second, it is an excellent tool for Monte Carlo…

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Hierarchical Mixture Modeling With Normalized Inverse-Gaussian Priors

采用归一化逆高斯先验的层级混合建模

In recent years the Dirichlet process prior has experienced a great success in the context of Bayesian mixture modeling. The idea of overcoming discreteness of its realizations by exploiting it in hierarchical models, combined with the development of suitable sampling techniques, represent one of the reasons of its popularity. In this article we propose the normalized inverse-Gaussian (N–IG) process as an alternative to the Dirichlet process to be used in Bayesian…

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Bayesian Likelihood Methods for Estimating the End Point of a Distribution

估计分布端点的贝叶斯似然方法

Summary We consider maximum likelihood methods for estimating the end point of a distribution. The likelihood function is modified by a prior distribution that is imposed on the location parameter. The prior is explicit and meaningful, and has a general form that adapts itself to different settings. Results on convergence rates and limiting distributions are given. In particular, it is shown that the limiting distribution is non-normal in non-regular cases. Parametric…

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Bayes Factors Based on Test Statistics

基于检验统计量的贝叶斯因子

Summary Traditionally, the use of Bayes factors has required the specification of proper prior distributions on model parameters that are implicit to both null and alternative hypotheses. I describe an approach to defining Bayes factors based on modelling test statistics. Because the distributions of test statistics do not depend on unknown model parameters, this approach eliminates much of the subjectivity that is normally associated with the definition of Bayes factors.…

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Bayesian Inference for Stochastic Multitype Epidemics in Structured Populations Via Random Graphs

利用随机图对结构化人群中的随机多类型传染病模型进行贝叶斯推断

Summary The paper is concerned with new methodology for statistical inference for final outcome infectious disease data using certain structured population stochastic epidemic models. A major obstacle to inference for such models is that the likelihood is both analytically and numerically intractable. The approach that is taken here is to impute missing information in the form of a random graph that describes the potential infectious contacts between individuals. This level…

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Bayesian adaptive designs for clinical trials

临床试验的贝叶斯自适应设计

A Bayesian adaptive design is proposed for a comparative two-armed clinical trial using decision-theoretic approaches. A loss function is specified, based on the cost for each patient and the costs of making incorrect decisions at the end of a trial. At each interim analysis, the decision to terminate or to continue the trial is based on the expected loss function while concurrently incorporating efficacy, futility and cost. The maximum number of interim analyses is…

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A note on composite likelihood inference and model selection

复合似然推断与模型选择札记

A composite likelihood consists of a combination of valid likelihood objects, usually related to small subsets of data. The merit of composite likelihood is to reduce the computational complexity so that it is possible to deal with large datasets and very complex models, even when the use of standard likelihood or Bayesian methods is not feasible. In this paper, we aim to suggest an integrated, general approach to inference and model selection using composite likelihood…

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Modelling Directional Dispersion through Hyperspherical Log-Splines

通过超球面对数样条建模方向性离散程度

Summary We introduce the directionally dispersed class of multivariate distributions, a generalization of the elliptical class. By allowing dispersion of multivariate random variables to vary with direction it is possible to generate a very wide and flexible class of distributions. Directionally dispersed distributions have a simple form for their density, which extends a spherically symmetric density function by including a function D modelling directional dispersion. Under…

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Spike and Slab Gene Selection for Multigroup Microarray Data

多组微阵列数据的尖峰与厚尾基因选择

DNA microarrays can provide insight into genetic changes that characterize different stages of a disease process. Accurate identification of these changes has significant therapeutic and diagnostic implications. Statistical analysis for multistage (multigroup) data is challenging, however. ANOVA-based extensions of two-sample Z-tests, a popular method for detecting differentially expressed genes in two groups, do not work well in multigroup settings. False detection rates…

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Bayesian Nonparametric Spatial Modeling With Dirichlet Process Mixing

基于狄利克雷过程混合的贝叶斯非参数空间建模

Customary modeling for continuous point-referenced data assumes a Gaussian process that is often taken to be stationary. When such models are fitted within a Bayesian framework, the unknown parameters of the process are assumed to be random, so a random Gaussian process results. Here we propose a novel spatial Dirichlet process mixture model to produce a random spatial process that is neither Gaussian nor stationary. We first develop a spatial Dirichlet process model for…

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The Profile Sampler

剖面似然采样器

We consider frequentist inference for the parametric component θ separately from the nuisance parameter η in semiparametric models based on sampling from the posterior of the profile likelihood. We prove that this procedure gives a first-order–correct approximation to the maximum likelihood estimator and consistent estimation of the efficient Fisher information for θ, without computing derivatives or using complicated numerical approximations. An exact Bayesian…

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Residual Diagnostics for Growth Mixture Models

增长混合模型的残差诊断

Growth mixture modeling has become a prominent tool for studying the heterogeneity of developmental trajectories within a population. In this article we develop graphical diagnostics to detect misspecification in growth mixture models regarding the number of growth classes, growth trajectory means, and covariance structures. For each model misspecification, we propose a different type of empirical Bayes residual to quantify the departure. Our procedure begins by imputing…

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The Joint Measurement of Technical and Allocative Inefficiencies

技术无效率与配置无效率的联合测度

This article estimates technical and allocative inefficiencies and increase in costs therefrom of individual firms using a translog cost system consisting of the cost function and the cost share equations. We call it a nonlinear random-effects system because technical and allocative inefficiencies are random (hence the term random effects) and are separated from the random noise terms appearing in each equation of the system, and because the inefficiency terms appear in the…

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Cursed Equilibrium

诅咒均衡

There is evidence that people do not fully take into account how other people's actions depend on these other people's information. This paper defines and applies a new equilibrium concept in games with private information, cursed equilibrium, which assumes that each player correctly predicts the distribution of other players' actions, but underestimates the degree to which these actions are correlated with other players' information. We apply the concept to common-values…

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Semiparametric Bayesian inference in multiple equation models

多方程模型中的半参数贝叶斯推断

Abstract This paper outlines an approach to Bayesian semiparametric regression in multiple equation models which can be used to carry out inference in seemingly unrelated regressions or simultaneous equations models with nonparametric components. The approach treats the points on each nonparametric regression line as unknown parameters and uses a prior on the degree of smoothness of each line to ensure valid posterior inference despite the fact that the number of parameters…

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A new class of generalized Bayes minimax ridge regression estimators

一类新的广义贝叶斯极小极大岭回归估计量

Let y=Aβ+ɛ, where y is an N×1 vector of observations, β is a p×1 vector of unknown regression coefficients, A is an N×p design matrix and ɛ is a spherically symmetric error term with unknown scale parameter σ. We consider estimation of β under general quadratic loss functions, and, in particular, extend the work of Strawderman [J. Amer. Statist. Assoc. 73 (1978) 623–627] and Casella [Ann. Statist. 8 (1980) 1036–1056, J. Amer. Statist. Assoc. 80 (1985) 753–758] by finding…

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Empirical Bayes selection of wavelet thresholds

小波阈值的经验贝叶斯选择

This paper explores a class of empirical Bayes methods for level-dependent threshold selection in wavelet shrinkage. The prior considered for each wavelet coefficient is a mixture of an atom of probability at zero and a heavy-tailed density. The mixing weight, or sparsity parameter, for each level of the transform is chosen by marginal maximum likelihood. If estimation is carried out using the posterior median, this is a random thresholding procedure; the estimation can also…

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Adaptive MCMC methods for inference on affine stochastic volatility models with jumps

含跳跃仿射随机波动率模型推断的自适应 MCMC 方法

In this paper we propose an efficient Markov chain Monte Carlo (MCMC) algorithm to estimate stochastic volatility models with jumps and affine structure. Our idea relies on the use of adaptive methods that aim at reducing the asymptotic variance of the estimates. We focus on the Delayed Rejection algorithm in order to find accurate proposals and to efficiently simulate the volatility path. Furthermore, Bayesian model selection is addressed through the use of reduced runs of…

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Modeling Parametric Evolution in a Random Utility Framework

随机效用框架中的参数演化建模

Random utility models have become standard econometric tools, allowing parameter inference for individual-level categorical choice data. Such models typically presume that changes in observed choices over time can be attributed to changes in either covariates or unobservables. We study how choice dynamics can be captured more faithfully by also directly modeling temporal changes in parameters, using a vector autoregressive process and Bayesian estimation. This approach…

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A Monte Carlo method for computing the marginal likelihood in nondecomposable Gaussian graphical models

非可分解高斯图模型边际似然的蒙特卡洛计算

A centred Gaussian model that is Markov with respect to an undirected graph G is characterised by the parameter set of its precision matrices which is the cone M+(G) of positive definite matrices with entries corresponding to the missing edges of G constrained to be equal to zero. In a Bayesian framework, the conjugate family for the precision parameter is the distribution with Wishart density with respect to the Lebesgue measure restricted to M+(G). We call this…

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