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贝叶斯:贝叶斯建模、后验推断与 MCMC。
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Smoothing spline ANOVA models for large data sets with Bernoulli observations and the randomized GACV

大规模伯努利数据的平滑样条 ANOVA 模型与随机化 GACV

We propose the randomized Generalized Approximate Cross Validation (ranGACV) method for choosing multiple smoothing parameters in penalized likelihood estimates for Bernoulli data. The method is intended for application with penalized likelihood smoothing spline ANOVA models. In addition we propose a class of approximate numerical methods for solving the penalized likelihood variational problem which, in conjunction with the ranGACV method allows the application of smoothing…

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Hierarchical Models: A Current Computational Perspective

层级模型:当时的计算视角

Hierarchical models (HMs) provide a flexible framework for modeling data. The ongoing development of techniques like the EM algorithm and Markov chain Monte Carlo has enabled statisticians to make use of increasingly more complicated HMs over the last few decades. In this article, we consider Bayesian and frequentist versions of a general, two-stage HM, and describe several examples from the literature that illustrate its versatility. Some key aspects of the computational…

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Inference for Deterministic Simulation Models: The Bayesian Melding Approach

确定性模拟模型的推断:贝叶斯融合方法

Deterministic simulation models are used in many areas of science, engineering, and policy making. Typically, these are complex models that attempt to capture underlying mechanisms in considerable detail, and they have many user-specified inputs. The inputs are often specified by some form of trial-and-error approach in which plausible values are postulated, the corresponding outputs inspected, and the inputs modified until plausible outputs are obtained. Here we address the…

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Asymptotic Distribution of P Values in Composite Null Models

复合原假设模型中 p 值的渐近分布

We investigate the compatibility of a null model H 0 with the data by calculating a p value; that is, the probability, under H 0, that a given test statistic T exceeds its observed value. When the null model consists of a single distribution, the p value is readily obtained, and it has a uniform distribution under H 0. On the other hand, when the null model depends on an unknown nuisance parameter θ one must somehow get rid of θ, (e.g., by estimating it) to calculate a p…

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P Values for Composite Null Models

复合原假设模型的p值

The problem of investigating compatibility of an assumed model with the data is investigated in the situation when the assumed model has unknown parameters. The most frequently used measures of compatibility are p values, based on statistics T for which large values are deemed to indicate incompatibility of the data and the model. When the null model has unknown parameters, p values are not uniquely defined. The proposals for computing a p value in such a situation include…

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Nonparametric Bayes Estimation of Contamination Levels Using Observations from the Residual Distribution

利用阈值以上样本非参数贝叶斯估计污染水平

Data on contamination concentrations for chromium from one of the EPA's toxic waste sites consist of independent and identically distributed (iid) measurements along with additional observations from the residual distribution. The residual sample is obtained by sampling from hot spots, where contamination concentrations are assumed to be above a given threshold value. The data are modeled using a nonparametric Bayes estimator of the distribution function. The Dirichlet…

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Bayesian Analysis and Mapping of Mortality Rates for Chronic Obstructive Pulmonary Disease

慢性阻塞性肺疾病死亡率的贝叶斯分析与制图

This article summarizes our research on estimation of age-specific and age-adjusted mortality rates for chronic obstructive pulmonary disease (COPD) for white males. Our objectives are more precise and informative displays (than previously available) of geographic variation of the age-specific mortality rates for COPD, and investigation of the relationships between the geographic variation in mortality rates and the corresponding variation in selected covariates. For a given…

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Spatial Poisson Regression for Health and Exposure Data Measured at Disparate Resolutions

不同空间分辨率健康与暴露数据的空间泊松回归

Ecological regression studies are widely used to examine relationships between disease rates for small geographical areas and exposure to environmental risk factors. The raw data for such studies, including disease cases, environmental pollution concentrations, and the reference population at risk, are typically measured at various levels of spatial aggregation but are accumulated to a common geographical scale to facilitate statistical analysis. In this traditional…

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A Bayesian Model for Fecundability and Sterility

受孕能力与不育的贝叶斯模型

There is increasing evidence that exposure to environmental toxins during key stages of development can disrupt the human reproductive system. Such effects have proven difficult to study due to the many behavioral and biological factors involved in human reproduction. We analyze data from a North Carolina fertility study to assess the effect of prenatal, childhood, and current cigarette smoking exposure on fecundability and sterility. We use a mixture model that adjusts for…

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Transmission of Pneumococcal Carriage in Families: A Latent Markov Process Model for Binary Longitudinal Data

家庭内肺炎链球菌携带传播:二元纵向数据的潜在马尔可夫过程模型

We present a Bayesian data augmentation model to estimate acquisition and clearance rates of carriage of Streptococcus pneumoniae (Pnc) bacteria. The panel observation data comprise 10 measurements of Pnc carriage (carrier/noncarrier of the bacteria) in all members of 97 families with young children over a period of 2 years. Using natural conditional independence assumptions, a transmission model is constructed for the unobserved dependent binary processes of the augmented…

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Nonparametric Bayes Estimation of Contamination Levels Using Observations from the Residual Distribution

利用阈值以上样本的污染水平非参数贝叶斯估计

Data on contamination concentrations for chromium from one of the EPA's toxic waste sites consist of independent and identically distributed (iid) measurements along with additional observations from the residual distribution. The residual sample is obtained by sampling from hot spots, where contamination concentrations are assumed to be above a given threshold value. The data are modeled using a nonparametric Bayes estimator of the distribution function. The Dirichlet…

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Flexible Empirical Bayes Estimation for Wavelets

灵活的小波经验贝叶斯估计

Summary Wavelet shrinkage estimation is an increasingly popular method for signal denoising and compression. Although Bayes estimators can provide excellent mean-squared error (MSE) properties, the selection of an effective prior is a difficult task. To address this problem, we propose empirical Bayes (EB) prior selection methods for various error distributions including the normal and the heavier-tailed Student t-distributions. Under such EB prior distributions, we obtain…

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Inference in Molecular Population Genetics

分子群体遗传学中的统计推断

Summary Full likelihood-based inference for modern population genetics data presents methodological and computational challenges. The problem is of considerable practical importance and has attracted recent attention, with the development of algorithms based on importance sampling (IS) and Markov chain Monte Carlo (MCMC) sampling. Here we introduce a new IS algorithm. The optimal proposal distribution for these problems can be characterized, and we exploit a detailed…

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Dealing With Label Switching in Mixture Models

混合模型中标签交换问题的处理

Summary In a Bayesian analysis of finite mixture models, parameter estimation and clustering are sometimes less straightforward than might be expected. In particular, the common practice of estimating parameters by their posterior mean, and summarizing joint posterior distributions by marginal distributions, often leads to nonsensical answers. This is due to the so-called ‘label switching’ problem, which is caused by symmetry in the likelihood of the model parameters. A…

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Econometric applications of maxmin expected utility

最大最小期望效用的计量经济学应用

Abstract Gilboa and Schmeidler (1989) develop a set of axioms for decision making under uncertainty. The axioms imply a utility function and a set of distributions such that the preference ordering is obtained by calculating expected utility with respect to each distribution in the set, and then taking the minimum of expected utility over the set. In a portfolio choice problem, the distributions are joint distributions for the data that will be available when the choice is…

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Loss function‐based evaluation of DSGE models

基于损失函数的 DSGE 模型评估

Abstract In this paper we propose a Bayesian econometric procedure for the evaluation and comparison of DSGE models. Unlike in many previous econometric approaches we explicitly take into account the possibility that the DSGE models are misspecified and introduce a reference model to complete the model space. Three loss functions are proposed to assess the discrepancy between DSGE model predictions and an overall posterior distribution of population characteristics that the…

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Daily exchange rate behaviour and hedging of currency risk

日度汇率行为与货币风险对冲

Abstract We construct models which enable a decision maker to analyse the implications of typical time series patterns of daily exchange rates for currency risk management. Our approach is Bayesian where extensive use is made of Markov chain Monte Carlo methods. The effects of several model characteristics (unit roots, GARCH, stochastic volatility, heavy‐tailed disturbance densities) are investigated in relation to the hedging strategies. Consequently, we can make a…

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