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Deconvolution Methods for Non-Parametric Inference in two-level Mixed Models

两层混合模型中非参数推断的反卷积方法

Summary We develop a general non-parametric approach to the analysis of clustered data via random effects. Assuming only that the link function is known, the regression functions and the distributions of both cluster means and observation errors are treated non-parametrically. Our argument proceeds by viewing the observation error at the cluster mean level as though it were a measurement error in an errors-in-variables problem, and using a deconvolution argument to access…

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A General Dynamical Statistical model with Causal Interpretation

Summary We develop a general dynamical model as a framework for causal interpretation. We first state a criterion of local independence in terms of measurability of processes that are involved in the Doob–Meyer decomposition of stochastic processes; then we define direct and indirect influence. We propose a definition of causal influence using the concepts of a ‘physical system’. This framework makes it possible to link descriptive and explicative statistical models, and…

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Two-Step Estimation for Inhomogeneous Spatial Point Processes

非齐次空间点过程的两步估计

Summary The paper is concerned with parameter estimation for inhomogeneous spatial point processes with a regression model for the intensity function and tractable second-order properties (K-function). Regression parameters are estimated by using a Poisson likelihood score estimating function and in the second step minimum contrast estimation is applied for the residual clustering parameters. Asymptotic normality of parameter estimates is established under certain mixing…

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Covariance-Regularized Regression and Classification for high Dimensional Problems

高维问题中的协方差正则化回归与分类

Summary We propose covariance-regularized regression, a family of methods for prediction in high dimensional settings that uses a shrunken estimate of the inverse covariance matrix of the features to achieve superior prediction. An estimate of the inverse covariance matrix is obtained by maximizing the log-likelihood of the data, under a multivariate normal model, subject to a penalty; it is then used to estimate coefficients for the regression of the response onto the…

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Splines for Financial Volatility

金融波动率的样条建模

Summary We propose a flexible generalized auto-regressive conditional heteroscedasticity type of model for the prediction of volatility in financial time series. The approach relies on the idea of using multivariate B-splines of lagged observations and volatilities. Estimation of such a B-spline basis expansion is constructed within the likelihood framework for non-Gaussian observations. As the dimension of the B-spline basis is large, i.e. many parameters, we use…

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On-Line Expectation–Maximization Algorithm for latent Data Models

潜变量模型的在线期望最大化算法

Summary We propose a generic on-line (also sometimes called adaptive or recursive) version of the expectation–maximization (EM) algorithm applicable to latent variable models of independent observations. Compared with the algorithm of Titterington, this approach is more directly connected to the usual EM algorithm and does not rely on integration with respect to the complete-data distribution. The resulting algorithm is usually simpler and is shown to achieve convergence to…

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Shrinkage Tuning Parameter Selection with a Diverging number of Parameters

参数数量发散时的收缩调节参数选择

Summary Contemporary statistical research frequently deals with problems involving a diverging number of parameters. For those problems, various shrinkage methods (e.g. the lasso and smoothly clipped absolute deviation) are found to be particularly useful for variable selection. Nevertheless, the desirable performances of those shrinkage methods heavily hinge on an appropriate selection of the tuning parameters. With a fixed predictor dimension, Wang and co-worker have…

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Approximate Bayesian Inference for Latent Gaussian models by using Integrated Nested Laplace Approximations

利用积分嵌套拉普拉斯近似进行潜在高斯模型的近似贝叶斯推断

Summary Structured additive regression models are perhaps the most commonly used class of models in statistical applications. It includes, among others, (generalized) linear models, (generalized) additive models, smoothing spline models, state space models, semiparametric regression, spatial and spatiotemporal models, log-Gaussian Cox processes and geostatistical and geoadditive models. We consider approximate Bayesian inference in a popular subset of structured additive…

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On Distribution-Weighted Partial Least Squares with Diverging Number of Highly Correlated Predictors

预测变量数量增长且高度相关时的分布加权偏最小二乘

Summary Because highly correlated data arise from many scientific fields, we investigate parameter estimation in a semiparametric regression model with diverging number of predictors that are highly correlated. For this, we first develop a distribution-weighted least squares estimator that can recover directions in the central subspace, then use the distribution-weighted least squares estimator as a seed vector and project it onto a Krylov space by partial least squares to…

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Smoothing Parameter Selection for a Class of Semiparametric Linear Models

一类半参数线性模型的平滑参数选择

Summary Spline-based approaches to non-parametric and semiparametric regression, as well as to regression of scalar outcomes on functional predictors, entail choosing a parameter controlling the extent to which roughness of the fitted function is penalized. We demonstrate that the equations determining two popular methods for smoothing parameter selection, generalized cross-validation and restricted maximum likelihood, share a similar form that allows us to prove several…

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Large-Scale Multiple Testing under Dependence

依赖结构下的大规模多重检验

Summary The paper considers the problem of multiple testing under dependence in a compound decision theoretic framework. The observed data are assumed to be generated from an underlying two-state hidden Markov model. We propose oracle and asymptotically optimal data-driven procedures that aim to minimize the false non-discovery rate FNR subject to a constraint on the false discovery rate FDR. It is shown that the performance of a multiple-testing procedure can be…

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Some Asymptotic Results on Generalized Penalized Spline Smoothing

广义惩罚样条平滑的若干渐近结果

Summary The paper discusses asymptotic properties of penalized spline smoothing if the spline basis increases with the sample size. The proof is provided in a generalized smoothing model allowing for non-normal responses. The results are extended in two ways. First, assuming the spline coefficients to be a priori normally distributed links the smoothing framework to generalized linear mixed models. We consider the asymptotic rates such that the Laplace approximation is…

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Variance Estimation in the Analysis of Microarray Data

微阵列数据分析中的方差估计

Summary Microarrays are one of the most widely used high throughput technologies. One of the main problems in the area is that conventional estimates of the variances that are required in the t-statistic and other statistics are unreliable owing to the small number of replications. Various methods have been proposed in the literature to overcome this lack of degrees of freedom problem. In this context, it is commonly observed that the variance increases proportionally with…

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Efficient Estimation of Auto-Regression Parameters and Innovation Distributions for Semiparametric Integer-Valued AR( p ) Models

半参数整数值 AR(p) 模型的自回归参数与创新分布有效估计

Summary Integer-valued auto-regressive (INAR) processes have been introduced to model non-negative integer-valued phenomena that evolve over time. The distribution of an INAR(p) process is essentially described by two parameters: a vector of auto-regression coefficients and a probability distribution on the non-negative integers, called an immigration or innovation distribution. Traditionally, parametric models are considered where the innovation distribution is assumed to…

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Parameter Estimation for Partially Observed Hypoelliptic Diffusions

部分观测亚椭圆扩散过程的参数估计

Summary Hypoelliptic diffusion processes can be used to model a variety of phenomena in applications ranging from molecular dynamics to audio signal analysis. We study parameter estimation for such processes in situations where we observe some components of the solution at discrete times. Since exact likelihoods for the transition densities are typically not known, approximations are used that are expected to work well in the limit of small intersample times Δt and large…

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Shrinkage Inverse Regression Estimation for Model-Free Variable Selection

用于无模型变量选择的收缩逆回归估计

Summary The family of inverse regression estimators that was recently proposed by Cook and Ni has proven effective in dimension reduction by transforming the high dimensional predictor vector to its low dimensional projections. We propose a general shrinkage estimation strategy for the entire inverse regression estimation family that is capable of simultaneous dimension reduction and variable selection. We demonstrate that the new estimators achieve consistency in variable…

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Fourier Analysis of Irregularly Spaced Data on R d

实数空间上不规则间隔数据的傅里叶分析

Summary The purpose of the paper is to propose a frequency domain approach for irregularly spaced data on Rd. We extend the original definition of a periodogram for time series to that for irregularly spaced data and define non-parametric and parametric spectral density estimators in a way that is similar to the classical approach. Introduction of the mixed asymptotics, which are one of the asymptotics for irregularly spaced data, makes it possible to provide asymptotic…

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A New Class of Models for Bivariate Joint Tails

一类新的二元联合尾部模型

Summary A fundamental issue in applied multivariate extreme value analysis is modelling dependence within joint tail regions. The primary focus of this work is to extend the classical pseudopolar treatment of multivariate extremes to develop an asymptotically motivated representation of extremal dependence that also encompasses asymptotic independence. Starting with the usual mild bivariate regular variation assumptions that underpin the coefficient of tail dependence as a…

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Non-Parametric Tests for Distributional Treatment Effect for Randomly Censored Responses

随机删失结果的分布处理效应非参数检验

Summary For a binary treatment ν = 0, 1 and the corresponding ‘potential response’Y0 for the control group (ν = 0) and Y1 for the treatment group (ν = 1), one definition of no treatment effect is that Y0 and Y1 follow the same distribution given a covariate vector X. Koul and Schick have provided a non-parametric test for no distributional effect when the realized response (1−ν)Y0+νY1 is fully observed and the distribution of X is the same across the two groups. This test is…

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Pseudomartingale Estimating Equations for Modulated Renewal Process Models

调制更新过程模型的伪鞅估计方程

Summary We adapt martingale estimating equations based on gap time information to a general intensity model for a single realization of a modulated renewal process. The consistency and asymptotic normality of the estimators is proved under ergodicity conditions. Previous work has considered either parametric likelihood analysis or semiparametric multiplicative models using partial likelihood. The framework is generally applicable to semiparametric and parametric models,…

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Empirical Bayes Confidence Intervals Shrinking Both Means and Variances

同时收缩均值与方差的经验贝叶斯置信区间

Summary We construct empirical Bayes intervals for a large number p of means. The existing intervals in the literature assume that variances σi2 are either equal or unequal but known. When the variances are unequal and unknown, the suggestion is typically to replace them by unbiased estimators Si2. However, when p is large, there would be advantage in ‘borrowing strength’ from each other. We derive double-shrinkage intervals for means on the basis of our empirical Bayes…

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A Bayesian Approach to Non-Parametric Monotone Function Estimation

非参数单调函数估计的贝叶斯方法

Summary The paper proposes two Bayesian approaches to non-parametric monotone function estimation. The first approach uses a hierarchical Bayes framework and a characterization of smooth monotone functions given by Ramsay that allows unconstrained estimation. The second approach uses a Bayesian regression spline model of Smith and Kohn with a mixture distribution of constrained normal distributions as the prior for the regression coefficients to ensure the monotonicity of…

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Bayesian Model Selection using Test Statistics

利用检验统计量进行贝叶斯模型选择

Summary Existing Bayesian model selection procedures require the specification of prior distributions on the parameters appearing in every model in the selection set. In practice, this requirement limits the application of Bayesian model selection methodology. To overcome this limitation, we propose a new approach towards Bayesian model selection that uses classical test statistics to compute Bayes factors between possible models. In several test cases, our approach produces…

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Consistent Model Selection and Data-Driven Smooth Tests for Longitudinal Data in the Estimating Equations Approach

估计方程框架下纵向数据的一致模型选择与数据驱动光滑检验

Summary Model selection for marginal regression analysis of longitudinal data is challenging owing to the presence of correlation and the difficulty of specifying the full likelihood, particularly for correlated categorical data. The paper introduces a novel Bayesian information criterion type model selection procedure based on the quadratic inference function, which does not require the full likelihood or quasi-likelihood. With probability approaching 1, the criterion…

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