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Simultaneous Estimation and Reduction of Nonconformity in Interlaboratory Studies

实验室间研究中的同时估计与不一致性降低

Summary Several procedures that are designed to reduce nonconformity in interlaboratory studies by shrinking data towards a consensus weighted mean are suggested. Some of them are shown to have a smaller quadratic risk than the vector sample means. Shrinkage towards a weighted mean in a random-effects model and a statistic appearing in models which allow for systematic errors are also considered. The results are illustrated by two examples of collaborative studies.

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Likelihood for Statistically Equivalent Models

统计等价模型下的似然推断

Summary In likelihood inference we usually assume that the model is fixed and then base inference on the corresponding likelihood function. Often, however, the choice of model is rather arbitrary, and there may be other models which fit the data equally well. We study robustness of likelihood inference over such ‘statistically equivalent’ models and suggest a simple ‘envelope likelihood’ to capture this aspect of model uncertainty. Robustness depends critically on how we…

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Local Additive Estimation

局部加性估计

Summary Additive models are popular in high dimensional regression problems owing to their flexibility in model building and optimality in additive function estimation. Moreover, they do not suffer from the so-called curse of dimensionality generally arising in non-parametric regression settings. Less known is the model bias that is incurred from the restriction to the additive class of models. We introduce a new class of estimators that reduces additive model bias, yet…

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On the use of Non-Local Prior Densities in Bayesian Hypothesis Tests

非局部先验密度在贝叶斯假设检验中的应用

Summary We examine philosophical problems and sampling deficiencies that are associated with current Bayesian hypothesis testing methodology, paying particular attention to objective Bayes methodology. Because the prior densities that are used to define alternative hypotheses in many Bayesian tests assign non-negligible probability to regions of the parameter space that are consistent with null hypotheses, resulting tests provide exponential accumulation of evidence in…

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Signed Directed Acyclic Graphs for Causal Inference

用于因果推断的带符号有向无环图

Summary Formal rules governing signed edges on causal directed acyclic graphs are described and it is shown how these rules can be useful in reasoning about causality. Specifically, the notions of a monotonic effect, a weak monotonic effect and a signed edge are introduced. Results are developed relating these monotonic effects and signed edges to the sign of the causal effect of an intervention in the presence of intermediate variables. The incorporation of signed edges in…

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Ordering and Selecting Components in Multivariate or Functional Data Linear Prediction

多元或函数型数据线性预测中的成分排序与选择

Summary The problem of component choice in regression-based prediction has a long history. The main cases where important choices must be made are functional data analysis, and problems in which the explanatory variables are relatively high dimensional vectors. Indeed, principal component analysis has become the basis for methods for functional linear regression. In this context the number of components can also be interpreted as a smoothing parameter, and so the viewpoint…

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Combining Probability Forecasts

概率预测的组合

Summary Linear pooling is by far the most popular method for combining probability forecasts. However, any non-trivial weighted average of two or more distinct, calibrated probability forecasts is necessarily uncalibrated and lacks sharpness. In view of this, linear pooling requires recalibration, even in the ideal case in which the individual forecasts are calibrated. Towards this end, we propose a beta-transformed linear opinion pool for the aggregation of probability…

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Combining Information from Multiple Surveys by using Regression for Efficient Small Domain Estimation

通过回归合并多项调查信息以提高小域估计效率

Summary In sample surveys of finite populations, subpopulations for which the sample size is too small for estimation of adequate precision are referred to as small domains. Demand for small domain estimates has been growing in recent years among users of survey data. We explore the possibility of enhancing the precision of domain estimators by combining comparable information collected in multiple surveys of the same population. For this, we propose a regression method of…

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Criteria for Surrogate end Points Based on Causal Distributions

基于因果分布的替代终点判据

Summary When a treatment has a positive average causal effect (ACE) on an intermediate variable or surrogate end point which in turn has a positive ACE on a true end point, the treatment may have a negative ACE on the true end point due to the presence of unobserved confounders, which is called the surrogate paradox. A criterion for surrogate end points based on ACEs has recently been proposed to avoid the surrogate paradox. For a continuous or ordinal discrete end point,…

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Local Composite Quantile Regression Smoothing: An Efficient and Safe Alternative to Local Polynomial Regression

局部复合分位数回归平滑:局部多项式回归的替代方法

Summary Local polynomial regression is a useful non-parametric regression tool to explore fine data structures and has been widely used in practice. We propose a new non-parametric regression technique called local composite quantile regression smoothing to improve local polynomial regression further. Sampling properties of the estimation procedure proposed are studied. We derive the asymptotic bias, variance and normality of the estimate proposed. The asymptotic relative…

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Sparse Partial Least Squares Regression for Simultaneous Dimension Reduction and Variable Selection

同时降维与变量选择的稀疏偏最小二乘回归

Summary Partial least squares regression has been an alternative to ordinary least squares for handling multicollinearity in several areas of scientific research since the 1960s. It has recently gained much attention in the analysis of high dimensional genomic data. We show that known asymptotic consistency of the partial least squares estimator for a univariate response does not hold with the very large p and small n paradigm. We derive a similar result for a multivariate…

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Controlling the Familywise Error Rate with Plug-in Estimator for the Proportion of True Null Hypotheses

利用真实零假设比例的插件估计控制族错误率

Summary Estimation of the number or proportion of true null hypotheses in multiple-testing problems has become an interesting area of research. The first important work in this field was performed by Schweder and Spjøtvoll. Among others, they proposed to use plug-in estimates for the proportion of true null hypotheses in multiple-test procedures to improve the power. We investigate the problem of controlling the familywise error rate FWER when such estimators are used as…

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Sparse Additive Models

稀疏加性模型

Summary We present a new class of methods for high dimensional non-parametric regression and classification called sparse additive models. Our methods combine ideas from sparse linear modelling and additive non-parametric regression. We derive an algorithm for fitting the models that is practical and effective even when the number of covariates is larger than the sample size. Sparse additive models are essentially a functional version of the grouped lasso of Yuan and Lin.…

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Bayesian Non-Parametric Inference for Species Variety with a Two-Parameter Poisson–Dirichlet Process Prior

双参数 Poisson–Dirichlet 过程先验下的物种多样性贝叶斯非参数推断

Summary A Bayesian non-parametric methodology has been recently proposed to deal with the issue of prediction within species sampling problems. Such problems concern the evaluation, conditional on a sample of size n, of the species variety featured by an additional sample of size m. Genomic applications pose the additional challenge of having to deal with large values of both n and m. In such a case the computation of the Bayesian non-parametric estimators is cumbersome and…

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A Hierarchical Eigenmodel for Pooled Covariance Estimation

用于协方差联合估计的层次特征向量模型

Summary Although the covariance matrices corresponding to different populations are unlikely to be exactly equal they can still exhibit a high degree of similarity. For example, some pairs of variables may be positively correlated across most groups, whereas the correlation between other pairs may be consistently negative. In such cases much of the similarity across covariance matrices can be described by similarities in their principal axes, which are the axes that are…

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Causal Inference in Outcome-Dependent Two-Phase Sampling Designs

结局依赖的两阶段抽样设计中的因果推断

Summary We consider estimation of the causal effect of a treatment on an outcome from observational data collected in two phases. In the first phase, a simple random sample of individuals is drawn from a population. On these individuals, information is obtained on treatment, outcome and a few low dimensional covariates. These individuals are then stratified according to these factors. In the second phase, a random subsample of individuals is drawn from each stratum, with…

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A Bayesian Discovery Procedure

一种贝叶斯发现程序

Summary We discuss a Bayesian discovery procedure for multiple-comparison problems. We show that, under a coherent decision theoretic framework, a loss function combining true positive and false positive counts leads to a decision rule that is based on a threshold of the posterior probability of the alternative. Under a semiparametric model for the data, we show that the Bayes rule can be approximated by the optimal discovery procedure, which was recently introduced by…

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Detecting Changes in the Mean of Functional Observations

函数型观测均值变化的检测

Summary Principal component analysis has become a fundamental tool of functional data analysis. It represents the functional data as Xi(t) = μ(t)+Σ1≤l<∞ηi, l+ vl(t), where μ is the common mean, vl are the eigenfunctions of the covariance operator and the ηi, l are the scores. Inferential procedures assume that the mean function μ(t) is the same for all values of i. If, in fact, the observations do not come from one population, but rather their mean changes at some point(s),…

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Tilting Methods for Assessing the Influence of Components in a Classifier

利用倾斜方法评估分类器中各分量的影响

Summary Many contemporary classifiers are constructed to provide good performance for very high dimensional data. However, an issue that is at least as important as good classification is determining which of the many potential variables provide key information for good decisions. Responding to this issue can help us to determine which aspects of the datagenerating mechanism (e.g. which genes in a genomic study) are of greatest importance in terms of distinguishing between…

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Semiparametric Estimation and Inference for Distributional and General Treatment Effects

分布性及一般处理效应的半参数估计与推断

Summary There is a large literature on methods of analysis for randomized trials with noncompliance which focuses on the effect of treatment on the average outcome. The paper considers evaluating the effect of treatment on the entire distribution and general functions of this effect. For distributional treatment effects, fully non-parametric and fully parametric approaches have been proposed. The fully non-parametric approach could be inefficient but the fully parametric…

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Bootstrapping Frequency Domain Tests in Multivariate Time Series with an Application to Comparing Spectral Densities

多元时间序列频域检验的自助法:谱密度比较应用

Summary We propose a general bootstrap procedure to approximate the null distribution of non-parametric frequency domain tests about the spectral density matrix of a multivariate time series. Under a set of easy-to-verify conditions, we establish asymptotic validity of the bootstrap procedure proposed. We apply a version of this procedure together with a new statistic to test the hypothesis that the spectral densities of not necessarily independent time series are equal. The…

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Hybrid Dirichlet Mixture Models for Functional Data

函数型数据的混合式 Dirichlet 混合模型

Summary In functional data analysis, curves or surfaces are observed, up to measurement error, at a finite set of locations, for, say, a sample of n individuals. Often, the curves are homogeneous, except perhaps for individual-specific regions that provide heterogeneous behaviour (e.g. ‘damaged’ areas of irregular shape on an otherwise smooth surface). Motivated by applications with functional data of this nature, we propose a Bayesian mixture model, with the aim of…

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Adaptively Varying-Coefficient Spatiotemporal Models

自适应变系数时空模型

Summary We propose an adaptive varying-coefficient spatiotemporal model for data that are observed irregularly over space and regularly in time. The model is capable of catching possible non-linearity (both in space and in time) and non-stationarity (in space) by allowing the auto-regressive coefficients to vary with both spatial location and an unknown index variable. We suggest a two-step procedure to estimate both the coefficient functions and the index variable, which is…

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Copula Structure Analysis

Copula结构分析

Summary We extend the standard approach of correlation structure analysis for dimension reduction of high dimensional statistical data. The classical assumption of a linear model for the distribution of a random vector is replaced by the weaker assumption of a model for the copula. For elliptical copulas a correlation-like structure remains, but different margins and non-existence of moments are possible. After introducing the new concept and deriving some theoretical…

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