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Adaptive and Dynamic Adaptive Procedures for False Discovery Rate Control and Estimation

错误发现率控制与估计的自适应及动态自适应程序

Summary Many methods for estimation or control of the false discovery rate (FDR) can be improved by incorporating information about π0, the proportion of all tested null hypotheses that are true. Estimates of π0 are often based on the number of p-values that exceed a threshold λ. We first give a finite sample proof for conservative point estimation of the FDR when the λ-parameter is fixed. Then we establish a condition under which a dynamic adaptive procedure, whose…

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Control Variates for Estimation Based on Reversible Markov Chain Monte Carlo Samplers

可逆马尔可夫链蒙特卡洛估计的控制变量方法

Summary A general methodology is introduced for the construction and effective application of control variates to estimation problems involving data from reversible Markov chain Monte Carlo samplers. We propose the use of a specific class of functions as control variates, and we introduce a new consistent estimator for the values of the coefficients of the optimal linear combination of these functions. For a specific Markov chain Monte Carlo scenario, the form and proposed…

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Conditional Quantile Analysis When Covariates are Functions, with Application to Growth Data

函数型协变量的条件分位数分析及生长数据应用

Summary Motivated by the conditional growth charts problem, we develop a method for conditional quantile analysis when predictors take values in a functional space. The method proposed aims at estimating conditional distribution functions under a generalized functional regression framework. This approach facilitates balancing of model flexibility and the curse of dimensionality for the infinite dimensional functional predictors. Its good performance in comparison with other…

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Variance Estimation Using Refitted Cross-Validation in Ultrahigh Dimensional Regression

超高维回归中基于重拟合交叉验证的方差估计

Summary Variance estimation is a fundamental problem in statistical modelling. In ultrahigh dimensional linear regression where the dimensionality is much larger than the sample size, traditional variance estimation techniques are not applicable. Recent advances in variable selection in ultrahigh dimensional linear regression make this problem accessible. One of the major problems in ultrahigh dimensional regression is the high spurious correlation between the unobserved…

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New Consistent and Asymptotically Normal Parameter Estimates for Random-Graph Mixture Models

随机图混合模型的一致且渐近正态的新参数估计

Summary Random-graph mixture models are very popular for modelling real data networks. Parameter estimation procedures usually rely on variational approximations, either combined with the expectation–maximization (EM) algorithm or with Bayesian approaches. Despite good results on synthetic data, the validity of the variational approximation is, however, not established. Moreover, these variational approaches aim at approximating the maximum likelihood or the maximum a…

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A Full Scale Approximation of Covariance Functions for Large Spatial Data Sets

大型空间数据协方差函数的全尺度近似

Summary Gaussian process models have been widely used in spatial statistics but face tremendous computational challenges for very large data sets. The model fitting and spatial prediction of such models typically require O(n3) operations for a data set of size n. Various approximations of the covariance functions have been introduced to reduce the computational cost. However, most existing approximations cannot simultaneously capture both the large- and the small-scale…

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Augmented Designs to Assess Principal Strata Direct Effects

用于评估主层直接效应的增强实验设计

Summary Many studies involving causal questions are often concerned with understanding the causal pathways by which a treatment affects an outcome. Thus, the concept of ‘direct’versus‘indirect’ effects comes into play. We tackle the problem of disentangling direct and indirect effects by investigating new augmented experimental designs, where the treatment is randomized, and the mediating variable is not forced, but only randomly encouraged. There are two key features of our…

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Estimation of Direct Effects for Survival Data by using the Aalen Additive Hazards Model

使用Aalen加性风险模型估计生存数据的直接效应

Summary We extend the definition of the controlled direct effect of a point exposure on a survival outcome, other than through some given, time-fixed intermediate variable, to the additive hazard scale. We propose two-stage estimators for this effect when the exposure is dichotomous and randomly assigned and when the association between the intermediate variable and the survival outcome is confounded only by measured factors, which may themselves be affected by the exposure.…

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Asymptotic Behaviour of the Posterior Distribution in Overfitted Mixture Models

过拟合混合模型中后验分布的渐近行为

Summary We study the asymptotic behaviour of the posterior distribution in a mixture model when the number of components in the mixture is larger than the true number of components: a situation which is commonly referred to as an overfitted mixture. We prove in particular that quite generally the posterior distribution has a stable and interesting behaviour, since it tends to empty the extra components. This stability is achieved under some restriction on the prior, which…

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Banded Regularization of Autocovariance Matrices in Application to Parameter Estimation and Forecasting of Time Series

自协方差矩阵的带状正则化:时间序列参数估计与预测

Summary The paper addresses a ‘large p–small n’ problem in a time series framework and considers properties of banded regularization of an empirical autocovariance matrix of a time series process. Utilizing the banded autocovariance matrix enables us to fit a much longer auto-regressive AR(p) model to the observed data than typically suggested by the Akaike information criterion, while controlling how many parameters are to be estimated precisely and the level of accuracy.…

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Optimal Detection of Heterogeneous and Heteroscedastic Mixtures

异质且异方差混合分布的最优检测

Summary The problem of detecting heterogeneous and heteroscedastic Gaussian mixtures is considered. The focus is on how the parameters of heterogeneity, heteroscedasticity and proportion of non-null component influence the difficulty of the problem. We establish an explicit detection boundary which separates the detectable region where the likelihood ratio test is shown to detect the presence of non-null effects reliably from the undetectable region where no method can do…

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Dynamic Multiscale Spatiotemporal Models for Gaussian Areal Data

Summary We introduce a new class of dynamic multiscale models for spatiotemporal processes arising from Gaussian areal data. Specifically, we use nested geographical structures to decompose the original process into multiscale coefficients which evolve through time following state space equations. Our approach naturally accommodates data that are observed on irregular grids as well as heteroscedasticity. Moreover, we propose a multiscale spatiotemporal clustering algorithm…

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An Explicit Link between Gaussian Fields and Gaussian Markov Random Fields: The Stochastic Partial Differential Equation Approach

高斯场与高斯马尔可夫随机场的显式联系:随机偏微分方程方法

Summary Continuously indexed Gaussian fields (GFs) are the most important ingredient in spatial statistical modelling and geostatistics. The specification through the covariance function gives an intuitive interpretation of the field properties. On the computational side, GFs are hampered with the big n problem, since the cost of factorizing dense matrices is cubic in the dimension. Although computational power today is at an all time high, this fact seems still to be a…

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Data-Driven Density Estimation in the Presence of Additive Noise with unknown Distribution

未知分布加性噪声下的数据驱动密度估计

Summary We study the model Y = X+ε. We assume that we have at our disposal independent identically distributed observations Y1,…,Yn and ε−1,…,ε−M. The (Xj)1 ⩽j ⩽n are independent identically distributed with density f, independent of the (εj)1 ⩽j ⩽n, independent identically distributed with density f. The aim of the paper is to estimate f without knowing f. We first define an estimator, for which we provide bounds for the integrated L2-risk. We consider ordinary smooth and…

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Bayesian Smoothing of Photon-Limited Images with Applications in Astronomy

光子稀少图像的贝叶斯平滑及其天文学应用

Summary We consider a multiscale model for intensities in photon-limited images using a Bayesian framework. A typical Dirichlet prior on relative intensities is not efficient in picking up structures owing to the continuity of intensities. We propose a novel prior using the so-called ‘Chinese restaurant process’ to create structures in the form of equal intensities of some neighbouring pixels. Simulations are conducted using several photon-limited images, which are common in…

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Thick Pen Transformation for Time Series

时间序列的粗笔变换

Summary Traditional visualization of time series data often consists of plotting the time series values against time and ‘connecting the dots’. We propose an alternative, multiscale visualization technique, motivated by the scale–space approach in computer vision. In brief, our method also ‘connects the dots’ but uses a range of pens of varying thicknesses for this. The resulting multiscale map, which is termed the thick pen transform, corresponds to viewing the time series…

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Adaptive Inference for the Mean of a Gaussian Process in Functional Data

函数型数据中高斯过程均值的自适应推断

Summary We propose and analyse fully data-driven methods for inference about the mean function of a Gaussian process from a sample of independent trajectories of the process, observed at random time points and corrupted by additive random error. Our methods are based on thresholded least squares estimators relative to an approximating function basis. The variable threshold levels are determined from the data and the resulting estimates adapt to the unknown sparsity of the…

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Multiscale Adaptive Regression Models for Neuroimaging Data

神经影像数据的多尺度自适应回归模型

Summary Neuroimaging studies aim to analyse imaging data with complex spatial patterns in a large number of locations (called voxels) on a two-dimensional surface or in a three-dimensional volume. Conventional analyses of imaging data include two sequential steps: spatially smoothing imaging data and then independently fitting a statistical model at each voxel. However, conventional analyses suffer from the same amount of smoothing throughout the whole image, the arbitrary…

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Self-Consistent Method for Density Estimation

密度估计的自洽方法

Summary The estimation of a density profile from experimental data points is a challenging problem, which is usually tackled by plotting a histogram. Prior assumptions on the nature of the density, from its smoothness to the specification of its form, allow the design of more accurate estimation procedures, such as maximum likelihood. Our aim is to construct a procedure that makes no explicit assumptions, but still providing an accurate estimate of the density. We introduce…

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Regression Shrinkage and Selection via The Lasso: A Retrospective

通过 Lasso 进行回归收缩与选择:回顾

Summary In the paper I give a brief review of the basic idea and some history and then discuss some developments since the original paper on regression shrinkage and selection via the lasso.

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Non-Parametric Bayesian Inference on Bivariate Extremes

二元极值的非参数贝叶斯推断

Summary The tail of a bivariate distribution function in the domain of attraction of a bivariate extreme value distribution may be approximated by that of its extreme value attractor. The extreme value attractor has margins that belong to a three-parameter family and a dependence structure which is characterized by a probability measure on the unit interval with mean equal to 12, which is called the spectral measure. Inference is done in a Bayesian framework using a censored…

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Functional Singular Component Analysis

函数型奇异成分分析

Summary Aiming at quantifying the dependence of pairs of functional data (X,Y), we develop the concept of functional singular value decomposition for covariance and functional singular component analysis, building on the concept of ‘canonical expansion’ of compact operators in functional analysis. We demonstrate the estimation of the resulting singular values, functions and components for the practically relevant case of sparse and noise-contaminated longitudinal data and…

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Regression for Compositional Data by using Distributions Defined on the Hypersphere

利用超球面分布进行成分数据回归

Summary Compositional data can be transformed to directional data by the square-root transformation and then modelled by using distributions defined on the hypersphere. One advantage of this approach is that zero components are catered for naturally in the models. The Kent distribution for directional data is a good candidate model because it has a sufficiently general covariance structure. We propose a new regression model which models the mean direction of the Kent…

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Robustness and Accuracy of Methods for High Dimensional Data Analysis Based on Student’s t -Statistic

基于Student t统计量的高维数据分析方法:稳健性与精度

Summary Student’s t-statistic is finding applications today that were never envisaged when it was introduced more than a century ago. Many of these applications rely on properties, e.g. robustness against heavy-tailed sampling distributions, that were not explicitly considered until relatively recently. We explore these features of the t-statistic in the context of its application to very high dimensional problems, including feature selection and ranking, the simultaneous…

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