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Causal Inference by using Invariant Prediction: Identification and Confidence Intervals

利用不变预测进行因果推断:识别与置信区间

Summary What is the difference between a prediction that is made with a causal model and that with a non-causal model? Suppose that we intervene on the predictor variables or change the whole environment. The predictions from a causal model will in general work as well under interventions as for observational data. In contrast, predictions from a non-causal model can potentially be very wrong if we actively intervene on variables. Here, we propose to exploit this invariance…

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A General Framework for Updating Belief Distributions

信念分布更新的一般框架

Summary We propose a framework for general Bayesian inference. We argue that a valid update of a prior belief distribution to a posterior can be made for parameters which are connected to observations through a loss function rather than the traditional likelihood function, which is recovered as a special case. Modern application areas make it increasingly challenging for Bayesians to attempt to model the true data-generating mechanism. For instance, when the object of…

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Variable Selection via Additive Conditional Independence

基于加性条件独立的变量选择

Summary We propose a non-parametric variable selection method which does not rely on any regression model or predictor distribution. The method is based on a new statistical relationship, called additive conditional independence, that has been introduced recently for graphical models. Unlike most existing variable selection methods, which target the mean of the response, the method proposed targets a set of attributes of the response, such as its mean, variance or entire…

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Tests for High Dimensional Generalized Linear Models

高维广义线性模型的检验

Summary We consider testing regression coefficients in high dimensional generalized linear models. By modifying the test statistic of Goeman and his colleagues for large but fixed dimensional settings, we propose a new test, based on an asymptotic analysis, that is applicable for diverging dimensions and is robust to accommodate a wide range of link functions. The power properties of the tests are evaluated asymptotically under two families of alternative hypotheses. In…

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Set Estimation from Reflected Brownian Motion

基于反射布朗运动的集合估计

Summary We study the problem of estimating a compact set S⊂Rd from a trajectory of a reflected Brownian motion in S with reflections on the boundary of S. We establish consistency and rates of convergence for various estimators of S and its boundary. This problem has relevant applications in ecology in estimating the home range of an animal on the basis of tracking data. There are a variety of studies on the habitat of animals that employ the notion of home range. The paper…

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Model Checking for Parametric Single-index Models: A Dimension Reduction Model-Adaptive Approach

参数单指标模型检验:降维模型自适应方法

Summary Local smoothing testing based on multivariate non-parametric regression estimation is one of the main model checking methodologies in the literature. However, the relevant tests suffer from the typical curse of dimensionality, resulting in slow rates of convergence to their limits under the null hypothesis and less deviation from the null hypothesis under alternative hypotheses. This problem prevents tests from maintaining the level of significance well and makes…

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Distance Shrinkage and Euclidean Embedding via Regularized Kernel Estimation

通过正则化核估计实现距离收缩与欧氏嵌入

Summary Although recovering a Euclidean distance matrix from noisy observations is a common problem in practice, how well this could be done remains largely unknown. To fill in this void, we study a simple distance matrix estimate based on the so-called regularized kernel estimate. We show that such an estimate can be characterized as simply applying a constant amount of shrinkage to all observed pairwise distances. This fact allows us to establish risk bounds for the…

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Estimation of a Two-component Mixture Model with Applications to Multiple Testing

双成分混合模型的估计及其多重检验应用

Summary We consider a two-component mixture model with one known component. We develop methods for estimating the mixing proportion and the unknown distribution non-parametrically, given independent and identically distributed data from the mixture model, using ideas from shape-restricted function estimation. We establish the consistency of our estimators. We find the rate of convergence and asymptotic limit of the estimator for the mixing proportion. Completely automated…

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Robust Inference in Sample Selection Models

样本选择模型中的稳健推断

Summary The problem of non-random sample selectivity often occurs in practice in many fields. The classical estimators introduced by Heckman are the backbone of the standard statistical analysis of these models. However, these estimators are very sensitive to small deviations from the distributional assumptions which are often not satisfied in practice. We develop a general framework to study the robustness properties of estimators and tests in sample selection models. We…

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Inference for Multiple Change Points in Time Series via Likelihood Ratio Scan Statistics

利用似然比扫描统计量推断时间序列的多个变点

Summary We propose a likelihood ratio scan method for estimating multiple change points in piecewise stationary processes. Using scan statistics reduces the computationally infeasible global multiple-change-point estimation problem to a number of single-change-point detection problems in various local windows. The computation can be efficiently performed with order O{npt log (n)}. Consistency for the estimated numbers and locations of the change points are established.…

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Principal Causal Effect Identification and Surrogate end point Evaluation by Multiple Trials

利用多项试验识别主层因果效应并评价替代终点

Summary Principal stratification is a causal framework to analyse randomized experiments with a post-treatment variable between the treatment and end point variables. Because the principal strata defined by the potential outcomes of the post-treatment variable are not observable, we generally cannot identify the causal effects within principal strata. Motivated by a real data set of phase III adjuvant colon cancer clinical trials, we propose approaches to identifying and…

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Making the Cut: Improved Ranking and Selection for Large-Scale Inference

划定入选名单:大规模推断中的排序与筛选改进

Summary Identifying leading measurement units from a large collection is a common inference task in various domains of large-scale inference. Testing approaches, which measure evidence against a null hypothesis rather than effect magnitude, tend to overpopulate lists of leading units with those associated with low measurement error. By contrast, local maximum likelihood approaches tend to favour units with high measurement error. Available Bayesian and empirical Bayesian…

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Double One-sided Cross-validation of Local Linear Hazards

局部线性风险率估计的双重单侧交叉验证

Summary The paper brings together the theory and practice of local linear kernel hazard estimation. Bandwidth selection is fully analysed, including double one-sided cross-validation that is shown to have good practical and theoretical properties. Insight is provided into the choice of the weighting function in the local linear minimization and it is pointed out that classical weighting sometimes lacks stability. A new semiparametric hazard estimator transforming the…

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Extensible Grids: Uniform Sampling on a Space Filling Curve

可扩展网格:空间填充曲线上的均匀采样

Summary We study the properties of points in [0,1]d generated by applying Hilbert's space filling curve to uniformly distributed points in [0, 1]. For deterministic sampling we obtain a discrepancy of O(n−1/d) for d⩾2. For random stratified sampling, and scrambled van der Corput points, we derive a mean-squared error of O(n−1−2/d) for integration of Lipschitz continuous integrands, when d⩾3. These rates are the same as those obtained by sampling on d-dimensional grids and…

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Generalized Additive and Index Models with Shape Constraints

带形状约束的广义加性模型与指数模型

Summary We study generalized additive models, with shape restrictions (e.g. monotonicity, convexity and concavity) imposed on each component of the additive prediction function. We show that this framework facilitates a non-parametric estimator of each additive component, obtained by maximizing the likelihood. The procedure is free of tuning parameters and under mild conditions is proved to be uniformly consistent on compact intervals. More generally, our methodology can be…

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Mixtures, Envelopes and Hierarchical Duality

混合表示、包络表示与层级对偶

Summary We develop a connection between mixture and envelope representations of objective functions that arise frequently in statistics. We refer to this connection by using the term ‘hierarchical duality’. Our results suggest an interesting and previously underexploited relationship between marginalization and profiling, or equivalently between the Fenchel–Moreau theorem for convex functions and the Bernstein–Widder theorem for Laplace transforms. We give several different…

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Bayesian Regularization of the Length of Memory in Reversible Sequences

可逆序列记忆长度的贝叶斯正则化

Summary Variable order Markov chains have been used to model discrete sequential data in a variety of fields. A host of methods exist to estimate the history-dependent lengths of memory which characterize these models and to predict new sequences. In several applications, the data-generating mechanism is known to be reversible, but combining this information with the procedures mentioned is far from trivial. We introduce a Bayesian analysis for reversible dynamics, which…

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Of Quantiles and Expectiles: Consistent Scoring Functions, Choquet Representations and Forecast Rankings

分位数与期望分位数:一致评分函数、Choquet 表示与预测排序

Summary In the practice of point prediction, it is desirable that forecasters receive a directive in the form of a statistical functional. For example, forecasters might be asked to report the mean or a quantile of their predictive distributions. When evaluating and comparing competing forecasts, it is then critical that the scoring function used for these purposes be consistent for the functional at hand, in the sense that the expected score is minimized when following the…

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Estimating Multivariate Volatility Models Equation by Equation

多元波动率模型的逐方程估计

Summary The paper investigates the estimation of a wide class of multivariate volatility models. Instead of estimating an m-multivariate volatility model, a much simpler and numerically efficient method consists in estimating m univariate generalized auto-regressive conditional heteroscedasticity type models equation by equation in the first step, and a correlation matrix in the second step. Strong consistency and asymptotic normality of the equation-by-equation estimator…

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High Dimensional Ordinary Least Squares Projection for Screening Variables

用于变量筛选的高维普通最小二乘投影

Summary Variable selection is a challenging issue in statistical applications when the number of predictors p far exceeds the number of observations n. In this ultrahigh dimensional setting, the sure independence screening procedure was introduced to reduce the dimensionality significantly by preserving the true model with overwhelming probability, before a refined second-stage analysis. However, the aforementioned sure screening property strongly relies on the assumption…

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Globally Efficient Non-Parametric Inference of Average Treatment Effects by Empirical Balancing Calibration Weighting

通过经验平衡校准加权实现平均处理效应的全局有效非参数推断

Summary The estimation of average treatment effects based on observational data is extremely important in practice and has been studied by generations of statisticians under different frameworks. Existing globally efficient estimators require non-parametric estimation of a propensity score function, an outcome regression function or both, but their performance can be poor in practical sample sizes. Without explicitly estimating either function, we consider a wide class of…

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Randomization Inference for Treatment Effect Variation

处理效应变异的随机化推断

Summary Applied researchers are increasingly interested in whether and how treatment effects vary in randomized evaluations, especially variation that is not explained by observed covariates. We propose a model-free approach for testing for the presence of such unexplained variation. To use this randomization-based approach, we must address the fact that the average treatment effect, which is generally the object of interest in randomized experiments, actually acts as a…

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Drift Estimation in Sparse Sequential Dynamic Imaging, With Application to Nanoscale Fluorescence Microscopy

稀疏序贯动态成像中的漂移估计及纳米荧光显微应用

Summary A major challenge in many modern superresolution fluorescence microscopy techniques at the nanoscale lies in the correct alignment of long sequences of sparse but spatially and temporally highly resolved images. This is caused by the temporal drift of the protein structure, e.g. due to temporal thermal inhomogeneity of the object of interest or its supporting area during the observation process. We develop a simple semiparametric model for drift correction in…

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Truncated Linear Models for Functional Data

函数型数据的截断线性模型

Summary A conventional linear model for functional data involves expressing a response variable Y in terms of the explanatory function X (t), via the model Y=a+∫Ib(t)X(t)dt+error, where a is a scalar, b is an unknown function and I=[0,α] is a compact interval. However, in some problems the support of b or X, I1 say, is a proper and unknown subset of I, and is a quantity of particular practical interest. Motivated by a real data example involving particulate emissions, we…

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