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基于随机生成辅助变量的统计推断AI 解读

Summary In most real life studies, auxiliary variables are available and are employed to explain and understand missing data patterns and to evaluate and control causal relationships with variables of interest. Usually their availability is assumed to be a fact, even if the variables are measured without the objectives of the study in mind. As a result, inference with missing data and causal inference require some assumptions that cannot easily be validated or checked. In…

大数据极限下的期望传播AI 解读

Summary Expectation propagation (EP) is a widely successful algorithm for variational inference. EP is an iterative algorithm used to approximate complicated distributions, typically to find a Gaussian approximation of posterior distributions. In many applications of this type, EP performs extremely well. Surprisingly, despite its widespread use, there are very few theoretical guarantees on Gaussian EP, and it is quite poorly understood. To analyse EP, we first introduce a…

受控实验设计中的最优事前平衡AI 解读

Summary We develop a unified theory of designs for controlled experiments that balance baseline covariates a priori (before treatment and before randomization) using the framework of minimax variance and a new method called kernel allocation. We show that any notion of a priori balance must go hand in hand with a notion of structure, since with no structure on the dependence of outcomes on baseline covariates complete randomization (no special covariate balance) is always…

函数型参数置信域与置信带的几何方法AI 解读

Summary Functional data analysis is now a well-established discipline of statistics, with its core concepts and perspectives in place. Despite this, there are still fundamental statistical questions which have received relatively little attention. One of these is the systematic construction of confidence regions for functional parameters. This work is concerned with developing, understanding and visualizing such regions. We provide a general strategy for constructing…

多元高斯过程驱动的时空 Cox 过程精确贝叶斯推断AI 解读

Summary We present a novel inference methodology to perform Bayesian inference for spatiotemporal Cox processes where the intensity function depends on a multivariate Gaussian process. Dynamic Gaussian processes are introduced to enable evolution of the intensity function over discrete time. The novelty of the method lies on the fact that no discretization error is involved despite the non-tractability of the likelihood function and infinite dimensionality of the problem.…

基于核的联合独立性检验AI 解读

Summary We investigate the problem of testing whether d possibly multivariate random variables, which may or may not be continuous, are jointly (or mutually) independent. Our method builds on ideas of the two-variable Hilbert–Schmidt independence criterion but allows for an arbitrary number of variables. We embed the joint distribution and the product of the marginals in a reproducing kernel Hilbert space and define the d-variable Hilbert–Schmidt independence criterion dHSIC…

有限空间上经验 Wasserstein 距离的统计推断AI 解读

Summary The Wasserstein distance is an attractive tool for data analysis but statistical inference is hindered by the lack of distributional limits. To overcome this obstacle, for probability measures supported on finitely many points, we derive the asymptotic distribution of empirical Wasserstein distances as the optimal value of a linear programme with random objective function. This facilitates statistical inference (e.g. confidence intervals for sample-based Wasserstein…

高维线性模型的拟合优度检验AI 解读

Summary We propose a framework for constructing goodness-of-fit tests in both low and high dimensional linear models. We advocate applying regression methods to the scaled residuals following either an ordinary least squares or lasso fit to the data, and using some proxy for prediction error as the final test statistic. We call this family residual prediction tests. We show that simulation can be used to obtain the critical values for such tests in the low dimensional…

利用可交换随机测度构造稀疏图AI 解读

Summary Statistical network modelling has focused on representing the graph as a discrete structure, namely the adjacency matrix. When assuming exchangeability of this array—which can aid in modelling, computations and theoretical analysis—the Aldous–Hoover theorem informs us that the graph is necessarily either dense or empty. We instead consider representing the graph as an exchangeable random measure and appeal to the Kallenberg representation theorem for this object. We…

直接与间接处理效应：工具变量下的因果链与中介分析AI 解读

Summary The paper discusses the non-parametric identification of causal direct and indirect effects of a binary treatment based on instrumental variables. We identify the indirect effect, which operates through a mediator (i.e. intermediate variable) that is situated on the causal path between the treatment and the outcome, as well as the unmediated direct effect of the treatment by using distinct instruments for the endogenous treatment and the endogenous mediator. We…

局部平稳时间序列的分位数谱分析AI 解读

Summary Classical spectral methods are subject to two fundamental limitations: they can account only for covariance-related serial dependences, and they require second-order stationarity. Much attention has been devoted lately to quantile-based spectral methods that go beyond covariance-based serial dependence features. At the same time, covariance-based methods relaxing stationarity into much weaker local stationarity conditions have been developed for a variety of time…

半参数剂量探索方法AI 解读

Summary We describe a new class of dose finding methods to be used in early phase clinical trials. Under some added parametric conditions the class reduces to the family of continual reassessment method (CRM) designs. Under some relaxation of the underlying structure the method is equivalent to the cumulative cohort design, the modified toxicity probability interval method or Bayesian optimal interval design classes of methods, which are non-parametric in nature whereas the…

暴露测量误差下超额相对风险回归的联合非参数校正估计AI 解读

Summary Observational epidemiological studies often confront the problem of estimating exposure–disease relationships when the exposure is not measured exactly. We investigate exposure measurement error in excess relative risk regression, which is a widely used model in radiation exposure effect research. In the study cohort, a surrogate variable is available for the true unobserved exposure variable. The surrogate variable satisfies a generalized version of the classical…

通过 ℓ1 融合惩罚实现凸聚类AI 解读

Summary We study the large sample behaviour of a convex clustering framework, which minimizes the sample within cluster sum of squares under an l 1 fusion constraint on the cluster centroids. This recently proposed approach has been gaining in popularity; however, its asymptotic properties have remained mostly unknown. Our analysis is based on a novel representation of the sample clustering procedure as a sequence of cluster splits determined by a sequence of maximization…

未知方差的异质正态观测之共同均值估计AI 解读

Summary To determine the common mean of heterogeneous normal observations, the Bayes procedures and the invariant maximum likelihood estimators of the weights forming the weighted means statistic are obtained when there are no variance estimates. The Bayes statistic is based on the reference, Geisser–Cornfield prior distribution which makes the posterior (discrete) distribution of the mean to be supported by the observed data with probabilities determined via the geometric…

响应延迟下序贯实验的贝叶斯决策模型AI 解读

Summary We propose a Bayesian decision theoretic model of a fully sequential experiment in which the real-valued primary end point is observed with delay. The goal is to identify the sequential experiment which maximizes the expected benefits of technology adoption decisions, minus sampling costs. The solution yields a unified policy defining the optimal ‘do not experiment’–‘fixed sample size experiment’–‘sequential experiment’ regions and optimal stopping boundaries for…

高维比例风险模型的检验与置信区间AI 解读

Summary The paper considers the problem of hypothesis testing and confidence intervals in high dimensional proportional hazards models. Motivated by a geometric projection principle, we propose a unified likelihood ratio inferential framework, including score, Wald and partial likelihood ratio statistics for hypothesis testing. Without assuming model selection consistency, we derive the asymptotic distributions of these test statistics, establish their semiparametric…

检测误差不确定时估计患病率的最优合并检测设计AI 解读

Summary We construct optimal designs for group testing experiments where the goal is to estimate the prevalence of a trait by using a test with uncertain sensitivity and specificity. Using optimal design theory for approximate designs, we show that the most efficient design for simultaneously estimating the prevalence, sensitivity and specificity requires three different group sizes with equal frequencies. However, if estimating prevalence as accurately as possible is the…

因子设计中的秩方法：关于非参数处理效应的假设检验AI 解读

Summary Existing tests for factorial designs in the non-parametric case are based on hypotheses formulated in terms of distribution functions. Typical null hypotheses, however, are formulated in terms of some parameters or effect measures, particularly in heteroscedastic settings. Here this idea is extended to non-parametric models by introducing a novel non-parametric analysis-of-variance type of statistic based on ranks or pseudoranks which is suitable for testing…

时变 ARCH 模型中的参数稳定性与半参数推断AI 解读

Summary We develop a complete methodology for detecting time varying or non-time-varying parameters in auto-regressive conditional heteroscedasticity (ARCH) processes. For this, we estimate and test various semiparametric versions of time varying ARCH models which include two well-known non-stationary ARCH-type models introduced in the econometrics literature. Using kernel estimation, we show that non-time-varying parameters can be estimated at the usual parametric rate of…

最小二乘估计的覆盖理论AI 解读

Summary A sensible use of an estimation method requires that assessment criteria for the quality of the estimate be available. We present a coverage theory for the least squares estimate. By suitably modifying the empirical costs, one constructs statistics that are guaranteed to cover with known probability the cost associated with a next, still unseen, member of the population. All results of this paper are distribution free and can be applied to least squares problems in…

用于估计最优个体化治疗规则的一致性辅助学习AI 解读

Summary We propose new concordance-assisted learning for estimating optimal individualized treatment regimes. We first introduce a type of concordance function for prescribing treatment and propose a robust rank regression method for estimating the concordance function. We then find treatment regimes, up to a threshold, to maximize the concordance function, named the prescriptive index. Finally, within the class of treatment regimes that maximize the concordance function, we…

跨站点迁移鼓励设计干预效应的稳健估计AI 解读

Summary We develop robust targeted maximum likelihood estimators (TMLEs) for transporting intervention effects from one population to another. Specifically, we develop TMLEs for three transported estimands: the intent-to-treat average treatment effect (ATE) and complier ATE, which are relevant for encouragement design interventions and instrumental variable analyses, and the ATE of the exposure on the outcome, which is applicable to any randomized or observational study. We…

随机投影集成分类AI 解读

Summary We introduce a very general method for high dimensional classification, based on careful combination of the results of applying an arbitrary base classifier to random projections of the feature vectors into a lower dimensional space. In one special case that we study in detail, the random projections are divided into disjoint groups, and within each group we select the projection yielding the smallest estimate of the test error. Our random-projection ensemble…