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异质个体化治疗效应下最优治疗决策的最大最小投影学习AI 解读

Summary A salient feature of data from clinical trials and medical studies is inhomogeneity. Patients not only differ in baseline characteristics, but also in the way that they respond to treatment. Optimal individualized treatment regimes are developed to select effective treatments based on patient's heterogeneity. However, the optimal treatment regime might also vary for patients across different subgroups. We mainly consider patients’ heterogeneity caused by groupwise…

存在无效工具变量时的因果效应置信区间：两阶段硬阈值与投票AI 解读

Summary A major challenge in instrumental variable (IV) analysis is to find instruments that are valid, or have no direct effect on the outcome and are ignorable. Typically one is unsure whether all of the putative IVs are in fact valid. We propose a general inference procedure in the presence of invalid IVs, called two-stage hard thresholding with voting. The procedure uses two hard thresholding steps to select strong instruments and to generate candidate sets of valid IVs.…

病例对照研究次要结局分位数回归的半参数有效估计AI 解读

Summary Analysing secondary outcomes is a common practice for case–control studies. Traditional secondary analysis employs either completely parametric models or conditional mean regression models to link the secondary outcome to covariates. In many situations, quantile regression models complement mean-based analyses and provide alternative new insights on the associations of interest. For example, biomedical outcomes are often highly asymmetric, and median regression is…

用共同因子建模非平稳多元计数时间序列AI 解读

Summary We develop a new parameter-driven model for multivariate time series of counts. The time series is not necessarily stationary. We model the mean process as the product of modulating factors and unobserved stationary processes. The former characterizes the long-run movement in the data, whereas the latter is responsible for rapid fluctuations and other unknown or unavailable covariates. The unobserved stationary processes evolve independently of the past observed…

基于辅助变量与梯度的采样算法AI 解读

Summary We introduce a new family of Markov chain Monte Carlo samplers that combine auxiliary variables, Gibbs sampling and Taylor expansions of the target density. Our approach permits the marginalization over the auxiliary variables, yielding marginal samplers, or the augmentation of the auxiliary variables, yielding auxiliary samplers. The well-known Metropolis-adjusted Langevin algorithm MALA and preconditioned Crank–Nicolson–Langevin algorithm pCNL are shown to be…

误设广义线性混合模型的渐近性质与信息准则AI 解读

Summary The problem of misspecification poses challenges in model selection. The paper studies the asymptotic properties of estimators for generalized linear mixed models with misspecification under the framework of conditional Kullback–Leibler divergence. A conditional generalized information criterion is introduced, and a model selection procedure is proposed by minimizing the criterion. We prove that the model selection procedure proposed is asymptotically loss efficient…

近似残差平衡：高维平均处理效应的去偏推断AI 解读

Summary There are many settings where researchers are interested in estimating average treatment effects and are willing to rely on the unconfoundedness assumption, which requires that the treatment assignment be as good as random conditional on pretreatment variables. The unconfoundedness assumption is often more plausible if a large number of pretreatment variables are included in the analysis, but this can worsen the performance of standard approaches to treatment effect…

估计的 Wold 表示与谱密度驱动的时间序列自助法AI 解读

Summary The second-order dependence structure of purely non-deterministic stationary processes is described by the coefficients of the famous Wold representation. These coefficients can be obtained by factorizing the spectral density of the process. This relationship together with some spectral density estimator is used to obtain consistent estimators of these coefficients. A spectral-density-driven bootstrap for time series is then developed which uses the entire sequence…

随机网络、图模型与可交换性AI 解读

Summary We study conditional independence relationships for random networks and their interplay with exchangeability. We show that, for finitely exchangeable network models, the empirical subgraph densities are maximum likelihood estimates of their theoretical counterparts. We then characterize all possible Markov structures for finitely exchangeable random graphs, thereby identifying a new class of Markov network models corresponding to bidirected Kneser graphs. In…

Summary Many contemporary large-scale applications involve building interpretable models linking a large set of potential covariates to a response in a non-linear fashion, such as when the response is binary. Although this modelling problem has been extensively studied, it remains unclear how to control the fraction of false discoveries effectively even in high dimensional logistic regression, not to mention general high dimensional non-linear models. To address such a…

高效评估模型预测表现的半监督方法AI 解读

Summary In many modern machine learning applications, the outcome is expensive or time consuming to collect whereas the predictor information is easy to obtain. Semi-supervised (SS) learning aims at utilizing large amounts of ‘unlabelled’ data along with small amounts of ‘labelled’ data to improve the efficiency of a classical supervised approach. Though numerous SS learning classification and prediction procedures have been proposed in recent years, no methods currently…

利用工具变量进行有界、高效且多重稳健的平均处理效应估计AI 解读

Summary Instrumental variables are widely used for estimating causal effects in the presence of unmeasured confounding. Under the standard instrumental variable model, however, the average treatment effect is only partially identifiable. To address this, we propose novel assumptions that enable identification of the average treatment effect. Our identification assumptions are clearly separated from model assumptions that are needed for estimation, so researchers are not…

基于距离协方差的高维相互独立性检验AI 解读

Summary We introduce an L2-type test for testing mutual independence and banded dependence structure for high dimensional data. The test is constructed on the basis of the pairwise distance covariance and it accounts for the non-linear and non-monotone dependences among the data, which cannot be fully captured by the existing tests based on either Pearson correlation or rank correlation. Our test can be conveniently implemented in practice as the limiting null distribution…

Summary Methodology is proposed to uncover structural breaks in functional data that is ‘fully functional’ in the sense that it does not rely on dimension reduction techniques. A thorough asymptotic theory is developed for a fully functional break detection procedure as well as for a break date estimator, assuming a fixed break size and a shrinking break size. The latter result is utilized to derive confidence intervals for the unknown break date. The main results highlight…

从多组高斯序列到函数型数据：一种 Stein 估计方法AI 解读

Summary We expand the notion of Gaussian sequence models to n experiments and propose a Stein estimation strategy which relies on pooling information across experiments. An oracle inequality is established to assess conditional risks given the underlying effects, based on which we can quantify the size of relative error and obtain a tuning-free recovery strategy that is easy to compute, produces model parsimony and extends to unknown variance. We show that the simultaneous…

分位数回归中的边际线性效应检验AI 解读

Summary The paper develops a new marginal testing procedure to detect significant predictors that are associated with the conditional quantiles of a scalar response. The idea is to fit the marginal quantile regression on each predictor one at a time, and then to base the test on the t-statistics that are associated with the most predictive predictors. A resampling method is devised to calibrate this test statistic, which has non-regular limiting behaviour due to the…

多元时间序列的半参数动态 max-copula 模型AI 解读

Summary The paper presents a novel non-linear framework for the construction of flexible multivariate dependence structure (i.e. copulas) from existing copulas based on a straightforward ‘pairwise max-’rule. The newly constructed max-copula has a closed form and has strong interpretability. Compared with the classical ‘linear symmetric’ mixture copula, the max-copula can be viewed as a ‘non-linear asymmetric’ framework. It is capable of modelling asymmetric dependence and…

基于极端期望分位数的尾部风险估计AI 解读

Summary We use tail expectiles to estimate alternative measures to the value at risk and marginal expected shortfall, which are two instruments of risk protection of utmost importance in actuarial science and statistical finance. The concept of expectiles is a least squares analogue of quantiles. Both are M-quantiles as the minimizers of an asymmetric convex loss function, but expectiles are the only M-quantiles that are coherent risk measures. Moreover, expectiles define…

高维混合模型成分协方差矩阵的结构检验AI 解读

Summary By studying the family of p-dimensional scale mixtures, the paper shows for the first time a non-trivial example where the eigenvalue distribution of the corresponding sample covariance matrix does not converge to the celebrated Marčenko–Pastur law. A different and new limit is found and characterized. The reasons for failure of the Marčenko–Pastur limit in this situation are found to be a strong dependence between the p-co-ordinates of the mixture. Next, we address…

矩阵变量回归与包络模型AI 解读

Summary Modern technology often generates data with complex structures in which both response and explanatory variables are matrix valued. Existing methods in the literature can tackle matrix-valued predictors but are rather limited for matrix-valued responses. We study matrix variate regressions for such data, where the response Y on each experimental unit is a random matrix and the predictor X can be either a scalar, a vector or a matrix, treated as non-stochastic in terms…

函数型同期线性模型的统一经验似然比检验及稀疏到稠密数据的相变AI 解读

Summary We consider the problem of testing functional constraints in a class of functional concurrent linear models where both the predictors and the response are functional data measured at discrete time points. We propose test procedures based on the empirical likelihood with bias-corrected estimating equations to conduct both pointwise and simultaneous inferences. The asymptotic distributions of the test statistics are derived under the null and local alternative…

具有社区结构的网络中节点受欢迎度的区块模型AI 解读

Summary The community structure that is observed in empirical networks has been of particular interest in the statistics literature, with a strong emphasis on the study of block models. We study an important network feature called node popularity, which is closely associated with community structure. Neither the classical stochastic block model nor its degree-corrected extension can satisfactorily capture the dynamics of node popularity as observed in empirical networks. We…

重新审视距离加权判别AI 解读

Summary Distance-weighted discrimination (DWD) is a modern margin-based classifier with an interesting geometric motivation. It was proposed as a competitor to the support vector machine (SVM). Despite many recent references on DWD, DWD is far less popular than the SVM, mainly because of computational and theoretical reasons. We greatly advance the current DWD methodology and its learning theory. We propose a novel thrifty algorithm for solving standard DWD and generalized…

基于稀疏投影的高维变点估计AI 解读

Summary Change points are a very common feature of ‘big data’ that arrive in the form of a data stream. We study high dimensional time series in which, at certain time points, the mean structure changes in a sparse subset of the co-ordinates. The challenge is to borrow strength across the co-ordinates to detect smaller changes than could be observed in any individual component series. We propose a two-stage procedure called inspect for estimation of the change points: first,…