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稀疏矩阵图模型AI 解读

Matrix-variate observations are frequently encountered in many contemporary statistical problems due to a rising need to organize and analyze data with structured information. In this article, we propose a novel sparse matrix graphical model for these types of statistical problems. By penalizing, respectively, two precision matrices corresponding to the rows and columns, our method yields a sparse matrix graphical model that synthetically characterizes the underlying…

含变换噪声数据分类中的反卷积AI 解读

In the present study, we consider the problem of classifying spatial data distorted by a linear transformation or convolution and contaminated by additive random noise. In this setting, we show that classifier performance can be improved if we carefully invert the data before the classifier is applied. However, the inverse transformation is not constructed so as to recover the original signal, and in fact, we show that taking the latter approach is generally inadvisable. We…

缺失数据下多元位置与散布的稳健估计AI 解读

Two main issues regarding data quality are data contamination (outliers) and data completion (missing data). These two problems have attracted much attention and research but surprisingly, they are seldom considered together. Popular robust methods such as S-estimators of multivariate location and scatter offer protection against outliers but cannot deal with missing data, except for the obviously inefficient approach of deleting all incomplete cases. We generalize the…

面向遥感应用的空间统计数据融合AI 解读

Aerosols are tiny solid or liquid particles suspended in the atmosphere; examples of aerosols include windblown dust, sea salts, volcanic ash, smoke from wildfires, and pollution from factories. The global distribution of aerosols is a topic of great interest in climate studies since aerosols can either cool or warm the atmosphere depending on their location, type, and interaction with clouds. Aerosol concentrations are important input components of global climate models,…

评论：错误发现比例、错误发现率与条件化的影响AI 解读

Accurate estimation of the false discovery proportion (FDP) and false discovery rate (FDR) is a problem that has been eagerly waiting for a solution. Fan, Han and Gu have found one. They have achieved this by both clarifying the concept of the problem and providing a feasible algorithmic solution. In this comment, I discuss some of the central concepts involving FDP and its estimation via conditioning in contrast with the estimators by Efron (2007) and Friguet et al. (2009).

时变自回归模型中波动方差函数的峰数识别AI 解读

In many applications, time series exhibit nonstationary behavior that might reasonably be modeled as a time-varying autoregressive (AR) process. In the context of such a model, we discuss the problem of testing for modality of the variance function. We propose a test of modality that is local and, when used iteratively, can be used to identify the total number of modes in a given series. This problem is closely related to peak detection and identification, which has…

随机块模型图的一致邻接谱嵌入AI 解读

We present a method to estimate block membership of nodes in a random graph generated by a stochastic blockmodel. We use an embedding procedure motivated by the random dot product graph model, a particular example of the latent position model. The embedding associates each node with a vector; these vectors are clustered via minimization of a square error criterion. We prove that this method is consistent for assigning nodes to blocks, as only a negligible number of nodes…

任意协方差依赖下的错误发现比例估计AI 解读

Multiple hypothesis testing is a fundamental problem in high dimensional inference, with wide applications in many scientific fields. In genome-wide association studies, tens of thousands of tests are performed simultaneously to find if any SNPs are associated with some traits and those tests are correlated. When test statistics are correlated, false discovery control becomes very challenging under arbitrary dependence. In the current paper, we propose a novel method based…

混合效应设计：对称性假设与缺失数据AI 解读

The classical F test for the hypothesis of no main fixed effects in the two-way crossed mixed effects design is derived under model assumptions that include normality, variance homogeneity, and symmetry. The symmetry assumption specifies that the random main and interaction effects are independent. While it is known that the F test is robust against violations of the normality assumption and/or the homoscedasticity assumption in the balanced case, the effects of the symmetry…

刻画非对称性与非线性的广义相关度量AI 解读

Applicability of Pearson's correlation as a measure of explained variance is by now well understood. One of its limitations is that it does not account for asymmetry in explained variance. Aiming to develop broad applicable correlation measures, we study a pair of generalized measures of correlation (GMC) that deals with asymmetries in explained variances, and linear or nonlinear relations between random variables. We present examples under which the paired measures are…

分位数回归模型的最优设计AI 解读

Despite their importance, optimal designs for quantile regression models have not been developed so far. In this article, we investigate the D-optimal design problem for nonlinear quantile regression analysis. We provide a necessary condition to check the optimality of a given design and use it to determine bounds for the number of support points of locally D-optimal designs. The results are illustrated, determining locally, Bayesian and standardized maximin D-optimal…

时间序列的混合野生自助法AI 解读

We introduce a new and simple bootstrap procedure for general linear processes, called the hybrid wild bootstrap. The hybrid wild bootstrap generates frequency domain replicates of the periodogram that imitate asymptotically correct the first- and second-order properties of the ordinary periodogram including its weak dependence structure at different frequencies. As a consequence, the hybrid wild bootstrapped periodogram succeeds in approximating consistently the…

使用结局加权学习估计个体化治疗规则AI 解读

There is increasing interest in discovering individualized treatment rules for patients who have heterogeneous responses to treatment. In particular, one aims to find an optimal individualized treatment rule which is a deterministic function of patient specific characteristics maximizing expected clinical outcome. In this paper, we first show that estimating such an optimal treatment rule is equivalent to a classification problem where each subject is weighted proportional…

正态混合模型成分数的推断AI 解读

Finite normal mixture models are used in a wide range of applications. Hypothesis testing on the order of the normal mixture is an important yet unsolved problem. Existing procedures often lack a rigorous theoretical foundation. Many are also hard to implement numerically. In this article, we develop a new method to fill the void in this important area. An effective expectation-maximization (EM) test is invented for testing the null hypothesis of arbitrary order m 0 under a…

多元核函数的非参数构造AI 解读

We propose a nonparametric method for constructing multivariate kernels tuned to the configuration of the sample, for density estimation in , d moderate. The motivation behind the approach is to break down the construction of the kernel into two parts: determining its overall shape and then its global concentration. We consider a framework that is essentially nonparametric, as opposed to the usual bandwidth matrix parameterization. The shape of the kernel to be employed is…

基于距离相关学习的特征筛选AI 解读

This paper is concerned with screening features in ultrahigh dimensional data analysis, which has become increasingly important in diverse scientific fields. We develop a sure independence screening procedure based on the distance correlation (DC-SIS, for short). The DC-SIS can be implemented as easily as the sure independence screening procedure based on the Pearson correlation (SIS, for short) proposed by Fan and Lv (2008). However, the DC-SIS can significantly improve the…

参与内生且存在误报时 SNAP 对儿童健康的效应识别AI 解读

The literature assessing the efficacy of the Supplemental Nutrition Assistance Program (SNAP), formerly known as the Food Stamp Program, has long puzzled over positive associations between SNAP receipt and various undesirable health outcomes such as food insecurity. Assessing the causal impacts of SNAP, however, is hampered by two key identification problems: endogenous selection into participation and extensive systematic underreporting of participation status. Using data…

用于违约概率预测的一类离散变换生存模型AI 解读

Corporate bankruptcy prediction plays a central role in academic finance research, business practice, and government regulation. Consequently, accurate default probability prediction is extremely important. We propose to apply a discrete transformation family of survival models to corporate default risk predictions. A class of Box-Cox transformations and logarithmic transformations is naturally adopted. The proposed transformation model family is shown to include the popular…

联合建模探针可测性与表达强度以检测可变剪接AI 解读

The exon tiling array offers a high throughput technology to search for aberrant splicing in biomedical research, but few methods of analysis for splicing detection have been tested both statistically and empirically. Noisy measurements on nonresponsive probe selection regions and outlying intensities at some of the samples tend to distort model-based assessments. We propose a robust analysis of variance approach that incorporates an informative model on probe measurability…

用于网络探索的多尺度社区块模型AI 解读

Real world networks exhibit a complex set of phenomena such as underlying hierarchical organization, multiscale interaction, and varying topologies of communities. Most existing methods do not adequately capture the intrinsic interplay among such phenomena. We propose a nonparametric Multiscale Community Blockmodel (MSCB) to model the generation of hierarchies in social communities, selective membership of actors to subsets of these communities, and the resultant networks…

多元离散数据的成对 Copula 构造AI 解读

Multivariate discrete response data can be found in diverse fields, including econometrics, finance, biometrics, and psychometrics. Our contribution, through this study, is to introduce a new class of models for multivariate discrete data based on pair copula constructions (PCCs) that has two major advantages. First, by deriving the conditions under which any multivariate discrete distribution can be decomposed as a PCC, we show that discrete PCCs attain highly flexible…

用于估计干预效应的结构嵌套累积失败时间模型AI 解读

In the presence of time-varying confounders affected by prior treatment, standard statistical methods for failure time analysis may be biased. Methods that correctly adjust for this type of covariate include the parametric g-formula, inverse probability weighted estimation of marginal structural Cox proportional hazards models, and g-estimation of structural nested accelerated failure time models. In this article, we propose a novel method to estimate the causal effect of a…

长度偏倚抽样下的复合偏似然估计：痴呆患病队列应用AI 解读

The Canadian Study of Health and Aging (CSHA) employed a prevalent cohort design to study survival after onset of dementia, where patients with dementia were sampled and the onset time of dementia was determined retrospectively. The prevalent cohort sampling scheme favors individuals who survive longer. Thus, the observed survival times are subject to length bias. In recent years, there has been a rising interest in developing estimation procedures for prevalent cohort…

大量零值纵向患者报告结局与生存时间的多层贝叶斯模型AI 解读

Regulatory approval of new therapies often depends on demonstrating prolonged survival. Particularly when these survival benefits are modest, consideration of therapeutic benefits to patient-reported outcomes (PROs) may add value to the traditional biomedical clinical trial endpoints. We extend a popular class of joint models for longitudinal and survival data to accommodate the excessive zeros common in PROs, building hierarchical Bayesian models that combine information…