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树结构响应的非参数回归模型AI 解读

Developments in science and technology over the last two decades has motivated the study of complex data objects. In this article, we consider the topological properties of a population of tree-structured objects. Our interest centers on modeling the relationship between a tree-structured response and other covariates. For tree-structured objects, this poses serious challenges since most regression methods rely on linear operations in Euclidean space. We generalize the…

高阶无穷小稳健性AI 解读

Using the von Mises expansion, we study the higher-order infinitesimal robustness of a general M-functional and characterize its second-order properties. We show that second-order robustness is equivalent to the boundedness of both the estimator’s estimating function and its derivative with respect to the parameter. It implies, at the same time, (i) variance robustness and (ii) robustness of higher-order saddlepoint approximations to the estimator’s finite sample density.…

结构加性回归模型中用于函数选择的尖峰—厚尾先验AI 解读

Fabian Scheipla, Ludwig Fahrmeira & Thomas Kneibb a Department of Statistics , Ludwig-Maximilians-Universität München , Munich , Germany b Department of Economics , Georg-August-Universität Göttingen , Göttingen , Germany Structured additive regression (STAR) provides a general framework for complex Gaussian and non-Gaussian regression models, with predictors comprising arbitrary combinations of nonlinear functions and surfaces, spatial effects, varying coefficients, random…

具有线性计算成本的最优变点检测AI 解读

In this article, we consider the problem of detecting multiple changepoints in large datasets. Our focus is on applications where the number of changepoints will increase as we collect more data: for example, in genetics as we analyze larger regions of the genome, or in finance as we observe time series over longer periods. We consider the common approach of detecting changepoints through minimizing a cost function over possible numbers and locations of changepoints. This…

重复函数型观测的建模AI 解读

We introduce a new methodological framework for repeatedly observed and thus dependent functional data, aiming at situations where curves are recorded repeatedly for each subject in a sample. Our methodology covers the case where the recordings of the curves are scheduled on a regular and dense grid and also situations more typical for longitudinal studies, where the timing of recordings is often sparse and random. The proposed models lead to an interpretable and…

二元结局的工具变量估计量AI 解读

Instrumental variables (IVs) can be used to construct estimators of exposure effects on the outcomes of studies affected by nonignorable selection of the exposure. Estimators that fail to adjust for the effects of nonignorable selection will be biased and inconsistent. Such situations commonly arise in observational studies, but are also a problem for randomized experiments affected by nonignorable noncompliance. In this article, we review IV estimators for studies in which…

同时降维与变量选择的稀疏降秩回归AI 解读

The reduced-rank regression is an effective method in predicting multiple response variables from the same set of predictor variables. It reduces the number of model parameters and takes advantage of interrelations between the response variables and hence improves predictive accuracy. We propose to select relevant variables for reduced-rank regression by using a sparsity-inducing penalty. We apply a group-lasso type penalty that treats each row of the matrix of the…

异方差层级模型中的 SURE 估计AI 解读

Hierarchical models are extensively studied and widely used in statistics and many other scientific areas. They provide an effective tool for combining information from similar resources and achieving partial pooling of inference. Since the seminal work by James and Stein (1961 James, W. and Stein, C. M. 1961. “Estimation With Quadratic Loss,”. Proceedings of the 4th Berkeley Symposium on Probability and Statistics, I: 367–379. [Google Scholar]) and Stein (1962 Stein, C. M.…

大型协方差矩阵的正定 ℓ1 惩罚估计AI 解读

The thresholding covariance estimator has nice asymptotic properties for estimating sparse large covariance matrices, but it often has negative eigenvalues when used in real data analysis. To fix this drawback of thresholding estimation, we develop a positive-definite ℓ1-penalized covariance estimator for estimating sparse large covariance matrices. We derive an efficient alternating direction method to solve the challenging optimization problem and establish its convergence…

重尾分布的高位条件分位数估计AI 解读

Estimation of conditional quantiles at very high or low tails is of interest in numerous applications. Quantile regression provides a convenient and natural way of quantifying the impact of covariates at different quantiles of a response distribution. However, high tails are often associated with data sparsity, so quantile regression estimation can suffer from high variability at tails especially for heavy-tailed distributions. In this article, we develop new estimation…

纳入短期事件时间信息的长期生存 Landmark 预测AI 解读

In recent years, a wide range of markers have become available as potential tools to predict risk or progression of disease. In addition to such biological and genetic markers, short term outcome information may be useful in predicting long term disease outcomes. When such information is available, it would be desirable to combine this along with predictive markers to improve the prediction of long term survival. Most existing methods for incorporating censored short term…

扩散过程参数估计的多分辨率方法AI 解读

Diffusion process models are widely used in science, engineering and finance. Most diffusion processes are described by stochastic differential equations in continuous time. In practice, however, data is typically only observed at discrete time points. Except for a few very special cases, no analytic form exists for the likelihood of such discretely observed data. For this reason, parametric inference is often achieved by using discrete-time approximations, with accuracy…

AdaptSPEC：非平稳时间序列的自适应谱估计AI 解读

We propose a method for analyzing possibly nonstationary time series by adaptively dividing the time series into an unknown but finite number of segments and estimating the corresponding local spectra by smoothing splines. The model is formulated in a Bayesian framework, and the estimation relies on reversible jump Markov chain Monte Carlo (RJMCMC) methods. For a given segmentation of the time series, the likelihood function is approximated via a product of local Whittle…

结合 Google 流感趋势数据与状态空间 SEIR 模型追踪疫情AI 解读

In this article, we use Google Flu Trends data together with a sequential surveillance model based on state-space methodology to track the evolution of an epidemic process over time. We embed a classical mathematical epidemiology model [a susceptible-exposed-infected-recovered (SEIR) model] within the state-space framework, thereby extending the SEIR dynamics to allow changes through time. The implementation of this model is based on a particle filtering algorithm, which…

基于惩罚可信区域的一致高维贝叶斯变量选择AI 解读

For high-dimensional data, particularly when the number of predictors greatly exceeds the sample size, selection of relevant predictors for regression is a challenging problem. Methods such as sure screening, forward selection, or penalized regressions are commonly used. Bayesian variable selection methods place prior distributions on the parameters along with a prior over model space, or equivalently, a mixture prior on the parameters having mass at zero. Since exhaustive…

将犯罪历程建模为对单峰总体年龄—犯罪曲线的偏离：大麻使用案例AI 解读

A major aim of longitudinal analyses of life course data is to describe the within- and between-individual variability in a behavioral outcome, such as crime. Statistical analyses of such data typically draw on mixture and mixed-effects growth models. In this work, we present a functional analytic point of view and develop an alternative method that models individual crime trajectories as departures from a population age-crime curve. Drawing on empirical and theoretical…

纵向观测的半参数变点回归模型AI 解读

Many longitudinal studies involve relating an outcome process to a set of possibly time-varying covariates, giving rise to the usual regression models for longitudinal data. When the purpose of the study is to investigate the covariate effects when experimental environment undergoes abrupt changes or to locate the periods with different levels of covariate effects, a simple and easy-to-interpret approach is to introduce change-points in regression coefficients. In this…

利用混合隶属度模型估计身份披露风险AI 解读

Statistical agencies and other organizations that disseminate data are obligated to protect data subjects' confidentiality. For example, ill-intentioned individuals might link data subjects to records in other databases by matching on common characteristics (keys). Successful links are particularly problematic for data subjects with combinations of keys that are unique in the population. Hence, as part of their assessments of disclosure risks, many data stewards estimate the…

参数受约束模型的 Minkowski–Weyl 先验：BioCycle 研究分析AI 解读

We propose a general framework for performing full Bayesian analysis under linear inequality parameter constraints. The proposal is motivated by the BioCycle Study, a large cohort study of hormone levels of healthy women where certain well-established linear inequality constraints on the log-hormone levels should be accounted for in the statistical inferential procedure. Based on the Minkowski–Weyl decomposition of polyhedral regions, we propose a class of priors that are…

复杂生物混合物代谢物解卷积与定量的贝叶斯核磁共振谱模型AI 解读

Nuclear magnetic resonance (NMR) spectra are widely used in metabolomics to obtain profiles of metabolites dissolved in biofluids such as cell supernatants. Methods for estimating metabolite concentrations from these spectra are presently confined to manual peak fitting and to binning procedures for integrating resonance peaks. Extensive information on the patterns of spectral resonance generated by human metabolites is now available in online databases. By incorporating…

考虑测量误差的病例序列模型：老年透析患者感染与心血管风险AI 解读

Infection and cardiovascular disease are leading causes of hospitalization and death in older patients on dialysis. Our recent work found an increase in the relative incidence of cardiovascular outcomes during the ~ 30 days after infection-related hospitalizations using the case series model, which adjusts for measured and unmeasured baseline confounders. However, a major challenge in modeling/assessing the infection-cardiovascular risk hypothesis is that the exact time of…

函数型因果中介分析及脑连接应用AI 解读

Mediation analysis is often used in the behavioral sciences to investigate the role of intermediate variables that lie on the causal path between a randomized treatment and an outcome variable. Typically, mediation is assessed using structural equation models (SEMs), with model coefficients interpreted as causal effects. In this article, we present an extension of SEMs to the functional data analysis (FDA) setting that allows the mediating variable to be a continuous…

可加模型的直接同时推断及营养不足建模应用AI 解读

This article proposes a simple and fast approach to build simultaneous confidence bands and perform specification tests for smooth curves in additive models. The method allows for handling of spatially heterogeneous functions and its derivatives as well as heteroscedasticity in the data. It is applied to study the determinants of chronic undernutrition of Kenyan children, with a particular focus on the highly nonlinear age pattern in undernutrition. Model estimation using…

函数型线性回归的极小极大与自适应预测AI 解读

This article considers minimax and adaptive prediction with functional predictors in the framework of functional linear model and reproducing kernel Hilbert space. Minimax rate of convergence for the excess prediction risk is established. It is shown that the optimal rate is determined jointly by the reproducing kernel and the covariance kernel. In particular, the alignment of these two kernels can significantly affect the difficulty of the prediction problem. In contrast,…