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Sparse Learning and Structure Identification for Ultrahigh-Dimensional Image-on-Scalar Regression

超高维图像对标量回归中的稀疏学习与结构识别

This article considers high-dimensional image-on-scalar regression, where the spatial heterogeneity of covariate effects on imaging responses is investigated via a flexible partially linear spatially varying coefficient model. To tackle the challenges of spatial smoothing over the imaging response’s complex domain consisting of regions of interest, we approximate the spatially varying coefficient functions via bivariate spline functions over triangulation. We first study…

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Smooth Backfitting of Proportional Hazards With Multiplicative Components

具有乘法分量的比例风险模型的光滑回代估计

Smooth backfitting has proven to have a number of theoretical and practical advantages in structured regression. By projecting the data down onto the structured space of interest smooth backfitting provides a direct link between data and estimator. This article introduces the ideas of smooth backfitting to survival analysis in a proportional hazard model, where we assume an underlying conditional hazard with multiplicative components. We develop asymptotic theory for the…

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Integrating Multisource Block-Wise Missing Data in Model Selection

模型选择中多来源分块缺失数据的整合

For multisource data, blocks of variable information from certain sources are likely missing. Existing methods for handling missing data do not take structures of block-wise missing data into consideration. In this article, we propose a multiple block-wise imputation (MBI) approach, which incorporates imputations based on both complete and incomplete observations. Specifically, for a given missing pattern group, the imputations in MBI incorporate more samples from groups…

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Bayesian Projected Calibration of Computer Models

计算机模型的贝叶斯投影校准

We develop a Bayesian approach called the Bayesian projected calibration to address the problem of calibrating an imperfect computer model using observational data from an unknown complex physical system. The calibration parameter and the physical system are parameterized in an identifiable fashion via the L2-projection. The physical system is imposed a Gaussian process prior distribution, which naturally induces a prior distribution on the calibration parameter through the…

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Spherical Regression Under Mismatch Corruption With Application to Automated Knowledge Translation

配对错配污染下的球面回归及自动知识转换应用

Motivated by a series of applications in data integration, language translation, bioinformatics, and computer vision, we consider spherical regression with two sets of unit-length vectors when the data are corrupted by a small fraction of mismatch in the response-predictor pairs. We propose a three-step algorithm in which we initialize the parameters by solving an orthogonal Procrustes problem to estimate a translation matrix W ignoring the mismatch. We then estimate a…

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Randomization Tests for Weak Null Hypotheses in Randomized Experiments

随机实验中弱零假设的随机化检验

The Fisher randomization test (FRT) is appropriate for any test statistic, under a sharp null hypothesis that can recover all missing potential outcomes. However, it is often sought after to test a weak null hypothesis that the treatment does not affect the units on average. To use the FRT for a weak null hypothesis, we must address two issues. First, we need to impute the missing potential outcomes although the weak null hypothesis cannot determine all of them. Second, we…

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Discussion of “A Gibbs Sampler for a Class of Random Convex Polytopes”

《一类随机凸多面体的 Gibbs 采样器》讨论

This very welcome article is a fascinating contribution to an important subject. Persistent questions about the lower and upper probabilities includeWhat does it do in simple problems?What does it ...

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Discussion of “A Gibbs Sampler for a Class of Random Convex Polytopes”

对《一类随机凸多面体的 Gibbs 抽样器》的讨论

I commend the authors for their efforts in revisiting the DS framework for statistical inference, but from a computational perspective. It is perhaps untraditional for the Theory and Methods sectio...

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Rejoinder—A Gibbs Sampler for a Class of Random Convex Polytopes

作者答复:一类随机凸多面体的Gibbs采样器

We present a Gibbs sampler for the Dempster-Shafer (DS) approach to statistical inference for Categorical distributions. The DS framework extends the Bayesian approach, allows in particular the use of partial prior information, and yields three-valued uncertainty assessments representing probabilities "for", "against", and "don't know" about formal assertions of interest. The proposed algorithm targets the distribution of a class of random convex polytopes which encapsulate…

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Thirty Years of The Network Scale-up Method

网络规模推算法三十年

Estimating the size of hard-to-reach populations is an important problem for many fields. The Network Scale-up Method (NSUM) is a relatively new approach to estimate the size of these hard-to-reach populations by asking respondents the question, "How many X's do you know," where X is the population of interest (e.g. "How many female sex workers do you know?"). The answers to these questions form Aggregated Relational Data (ARD). The NSUM has been used to estimate the size of…

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Count Time Series: A Methodological Review

计数时间序列:方法综述

A growing interest in non-Gaussian time series, particularly in series comprised of nonnegative integers (counts), is taking place in today’s statistics literature. Count series naturally arise in fields, such as agriculture, economics, epidemiology, finance, geology, meteorology, and sports. Unlike stationary Gaussian series where autoregressive moving-averages are the primary modeling vehicle, no single class of models dominates the count landscape. As such, the literature…

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A Gibbs Sampler for a Class of Random Convex Polytopes

一类随机凸多面体的 Gibbs 采样器

We present a Gibbs sampler for the Dempster–Shafer (DS) approach to statistical inference for categorical distributions. The DS framework extends the Bayesian approach, allows in particular the use of partial prior information, and yields three-valued uncertainty assessments representing probabilities “for,” “against,” and “don’t know” about formal assertions of interest. The proposed algorithm targets the distribution of a class of random convex polytopes which encapsulate…

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Marginalized Frailty-Based Illness-Death Model: Application to the UK-Biobank Survival Data

基于边际化脆弱性的疾病—死亡模型:英国生物样本库应用

The UK Biobank is a large-scale health resource comprising genetic, environmental, and medical information on approximately 500,000 volunteer participants in the United Kingdom, recruited at ages 40–69 during the years 2006–2010. The project monitors the health and well-being of its participants. This work demonstrates how these data can be used to yield the building blocks for an interpretable risk-prediction model, in a semiparametric fashion, based on known genetic and…

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Evaluation of the health impacts of the 1990 Clean Air Act Amendments using causal inference and machine learning

利用因果推断与机器学习评估1990年《清洁空气法》修正案的健康影响

We develop a causal inference approach to estimate the number of adverse health events that were prevented due to changes in exposure to multiple pollutants attributable to a large-scale air quality intervention/regulation, with a focus on the 1990 Clean Air Act Amendments (CAAA). We introduce a causal estimand called the Total Events Avoided (TEA) by the regulation, defined as the difference in the number of health events expected under the no-regulation pollution exposures…

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Bayesian Semiparametric Longitudinal Drift-Diffusion Mixed Models for Tone Learning in Adults

成人声调学习的贝叶斯半参数纵向漂移扩散混合模型

Understanding how adult humans learn nonnative speech categories such as tone information has shed novel insights into the mechanisms underlying experience-dependent brain plasticity. Scientists have traditionally examined these questions using longitudinal learning experiments under a multi-category decision making paradigm. Drift-diffusion processes are popular in such contexts for their ability to mimic underlying neural mechanisms. Motivated by these problems, we develop…

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Evaluating Proxy Influence in Assimilated Paleoclimate Reconstructions—Testing the Exchangeability of Two Ensembles of Spatial Processes

评估同化古气候重建中的代理资料影响:检验两组空间过程的可交换性

–Climate field reconstructions (CFRs) attempt to estimate spatiotemporal fields of climate variables in the past using climate proxies such as tree rings, ice cores, and corals. Data assimilation (DA) methods are a recent and promising new means of deriving CFRs that optimally fuse climate proxies with climate model output. Despite the growing application of DA-based CFRs, little is understood about how much the assimilated proxies change the statistical properties of the…

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Using Maximum Entry-Wise Deviation to Test the Goodness of Fit for Stochastic Block Models

利用最大逐元素偏差检验随机区块模型的拟合优度

–The stochastic block model is widely used for detecting community structures in network data. How to test the goodness of fit of the model is one of the fundamental problems and has gained growing interests in recent years. In this article, we propose a novel goodness-of-fit test based on the maximum entry of the centered and rescaled adjacency matrix for the stochastic block model. One noticeable advantage of the proposed test is that the number of communities can be…

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Nonparametric Estimation of Galaxy Cluster Emissivity and Detection of Point Sources in Astrophysics With Two Lasso Penalties

利用双重 Lasso 惩罚非参数估计星系团辐射率并检测点源

Astrophysicists are interested in recovering the three-dimensional gas emissivity of a galaxy cluster from a two-dimensional telescope image. Blurring and point sources make this inverse problem harder to solve. The conventional approach requires in a first step to identify and mask the point sources. Instead we model all astrophysical components in a single Poisson generalized linear model. To enforce sparsity on the parameters, maximum likelihood estimation is regularized…

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Bayesian Copula Density Deconvolution for Zero-Inflated Data in Nutritional Epidemiology

营养流行病学零膨胀数据的贝叶斯 Copula 密度反卷积

Estimating the marginal and joint densities of the long-term average intakes of different dietary components is an important problem in nutritional epidemiology. Since these variables cannot be directly measured, data are usually collected in the form of 24-hour recalls of the intakes, which show marked patterns of conditional heteroscedasticity. Significantly compounding the challenges, the recalls for episodically consumed dietary components also include exact zeros. The…

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Network Dependence Can Lead to Spurious Associations and Invalid Inference

网络依赖可能导致虚假关联与无效推断

Researchers across the health and social sciences generally assume that observations are independent, even while relying on convenience samples that draw subjects from one or a small number of communities, schools, hospitals, etc. A paradigmatic example of this is the Framingham Heart Study (FHS). Many of the limitations of such samples are well-known, but the issue of statistical dependence due to social network ties has not previously been addressed. We show that, along…

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Multivariate Postprocessing Methods for High-Dimensional Seasonal Weather Forecasts

高维季节性天气预测的多元后处理方法

–Seasonal weather forecasts are crucial for long-term planning in many practical situations and skillful forecasts may have substantial economic and humanitarian implications. Current seasonal forecasting models require statistical postprocessing of the output to correct systematic biases and unrealistic uncertainty assessments. We propose a multivariate postprocessing approach using covariance tapering, combined with a dimension reduction step based on principal component…

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Training Neural Networks as Learning Data-adaptive Kernels: Provable Representation and Approximation Benefits

神经网络训练作为数据自适应核学习:表示与逼近收益

Consider the problem: given the data pair (x,y) drawn from a population with f*(x)=E[y|x=x], specify a neural network model and run gradient flow on the weights over time until reaching any stationarity. How does ft , the function computed by the neural network at time t, relate to f*, in terms of approximation and representation? What are the provable benefits of the adaptive representation by neural networks compared to the pre-specified fixed basis representation in the…

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Bayesian Factor Analysis for Inference on Interactions

用于交互作用推断的贝叶斯因子分析

This article is motivated by the problem of inference on interactions among chemical exposures impacting human health outcomes. Chemicals often co-occur in the environment or in synthetic mixtures and as a result exposure levels can be highly correlated. We propose a latent factor joint model, which includes shared factors in both the predictor and response components while assuming conditional independence. By including a quadratic regression in the latent variables in the…

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Inference on Selected Subgroups in Clinical Trials

临床试验中经选择子群的统计推断

When existing clinical trial data suggest a promising subgroup, we must address the question of how good the selected subgroup really is. The usual statistical inference applied to the selected subgroup, assuming that the subgroup is chosen independent of the data, may lead to an overly optimistic evaluation of the selected subgroup. In this article, we address the issue of selection bias and develop a de-biasing bootstrap inference procedure for the best selected subgroup…

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