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《利用不完整数据理解 COVID-19 疫情动态的回归模型》讨论AI 解读

We would like to congratulate Quick, Dey, and Lin on developing the flexible statistical modeling framework MERMAID for assessing transmissibility of COVID-19 and associated drivers with incomplete...

合成控制方法的预测区间AI 解读

Uncertainty quantification is a fundamental problem in the analysis and interpretation of synthetic control (SC) methods. We develop conditional prediction intervals in the SC framework, and provide conditions under which these intervals offer finite-sample probability guarantees. Our method allows for covariate adjustment and non-stationary data. The construction begins by noting that the statistical uncertainty of the SC prediction is governed by two distinct sources of…

结合匹配与合成控制以权衡外推和内插偏差AI 解读

The synthetic control (SC) method is widely used in comparative case studies to adjust for differences in pre-treatment characteristics. SC limits extrapolation bias at the potential expense of interpolation bias, whereas traditional matching estimators have the opposite properties. This complementarity motives us to propose a matching and synthetic control (or MASC) estimator as a model averaging estimator that combines the standard SC and matching estimators. We show how…

面向细分数据的惩罚合成控制估计量AI 解读

Synthetic control methods are commonly applied in empirical research to estimate the effects of treatments or interventions on aggregate outcomes. A synthetic control estimator compares the outcome of a treated unit to the outcome of a weighted average of untreated units that best resembles the characteristics of the treated unit before the intervention. When disaggregated data are available, constructing separate synthetic controls for each treated unit may help avoid…

交错采用处理的观察性研究中的随机化检验AI 解读

This article considers the problem of inference in observational studies with time-varying adoption of treatment. In addition to an unconfoundedness assumption that the potential outcomes are independent of the times at which units adopt treatment conditional on the units’ observed characteristics, our analysis assumes that the time at which each unit adopts treatment follows a Cox proportional hazards model. This assumption permits the time at which each unit adopts…

矩阵补全、反事实与缺失数据的因子分析AI 解读

This paper proposes an imputation procedure that uses the factors estimated from a tall block along with the re-rotated loadings estimated from a wide block to impute missing values in a panel of data. Assuming that a strong factor structure holds for the full panel of data and its sub-blocks, it is shown that the common component can be consistently estimated at four different rates of convergence without requiring regularization or iteration. An asymptotic analysis of the…

大量时期与大量对照单位下合成控制估计量的性质AI 解读

We consider the asymptotic properties of the synthetic control (SC) estimator when both the number of pretreatment periods and control units are large. If potential outcomes follow a linear factor model, we provide conditions under which the SC unit asymptotically recovers the factor structure of the treated unit, even when the pretreatment fit is imperfect. This happens when there are weights diluted among an increasing number of control units such that a weighted average…

人工对照的反事实分析：推断、高维与非平稳性AI 解读

Recently, there has been growing interest in developing statistical tools to conduct counterfactual analysis with aggregate data when a single “treated” unit suffers an intervention, such as a policy change, and there is no obvious control group. Usually, the proposed methods are based on the construction of an artificial counterfactual from a pool of “untre ated” peers, organized in a panel data structure. In this article, we consider a general framework for counterfactual…

增广合成控制法AI 解读

The synthetic control method (SCM) is a popular approach for estimating the impact of a treatment on a single unit in panel data settings. The “synthetic control” is a weighted average of control units that balances the treated unit’s pretreatment outcomes and other covariates as closely as possible. A critical feature of the original proposal is to use SCM only when the fit on pretreatment outcomes is excellent. We propose Augmented SCM as an extension of SCM to settings…

主成分回归的稳健性AI 解读

Principal component regression (PCR) is a simple, but powerful and ubiquitously utilized method. Its effectiveness is well established when the covariates exhibit low-rank structure. However, its ability to handle settings with noisy, missing, and mixed-valued, that is, discrete and continuous, covariates is not understood and remains an important open challenge. As the main contribution of this work, we establish the robustness of PCR, without any change, in this respect…

反事实与合成控制的精确稳健共形推断方法AI 解读

We introduce new inference procedures for counterfactual and synthetic control methods for policy evaluation. We recast the causal inference problem as a counterfactual prediction and a structural breaks testing problem. This allows us to exploit insights from conformal prediction and structural breaks testing to develop permutation inference procedures that accommodate modern high-dimensional estimators, are valid under weak and easy-to-verify conditions, and are provably…

因果面板数据模型的矩阵补全方法AI 解读

In this paper we study methods for estimating causal effects in settings with panel data, where some units are exposed to a treatment during some periods and the goal is estimating counterfactual (untreated) outcomes for the treated unit/period combinations. We propose a class of matrix completion estimators that uses the observed elements of the matrix of control outcomes corresponding to untreated unit/periods to impute the "missing" elements of the control outcome matrix,…

离散马尔可夫随机场及相关图模型的采样算法AI 解读

Discrete Markov random fields are undirected graphical models in which the nodes of a graph are discrete random variables with values usually represented by colors. Typically, graphs are taken to be square lattices, although more general graphs are also of interest. Such discrete MRFs have been studied in many disciplines. We describe the two most popular types of discrete MRFs, namely the two-state Ising model and the q-state Potts model, and variations such as the cellular…

处理不完整依从信息的贝叶斯分层 CACE 模型：硬膜外镇痛与剖宫产的荟萃分析AI 解读

Noncompliance with assigned treatments is a common challenge in analyzing and interpreting randomized clinical trials (RCTs). One way to handle noncompliance is to estimate the complier-average causal effect (CACE), the intervention's efficacy in the subpopulation that complies with assigned treatment. In a two-step meta-analysis, one could first estimate CACE for each study, then combine them to estimate the population-averaged CACE. However, when some trials do not report…

利用互联网搜索数据与 PRISM 预测失业保险初次申请人数AI 解读

Big data generated from the Internet offer great potential for predictive analysis. Here we focus on using online users’ Internet search data to forecast unemployment initial claims weeks into the future, which provides timely insights into the direction of the economy. To this end, we present a novel method Penalized Regression with Inferred Seasonality Module (PRISM), which uses publicly available online search data from Google. PRISM is a semiparametric method, motivated…

半参数核独立性检验及其突变特征应用AI 解读

Cancers arise owing to somatic mutations, and the characteristic combinations of somatic mutations form mutational signatures. Despite many mutational signatures being identified, mutational processes underlying a number of mutational signatures remain unknown, which hinders the identification of interventions that may reduce somatic mutation burdens and prevent the development of cancer. We demonstrate that the unknown cause of a mutational signature can be inferred by the…

刻画有向脑网络的贝叶斯状态空间方法AI 解读

The human brain is a directional network system of brain regions involving directional connectivity. Seizures are a directional network phenomenon as abnormal neuronal activities start from a seizure onset zone (SOZ) and propagate to otherwise healthy regions. To localize the SOZ of an epileptic patient, clinicians use intracranial electroencephalography (iEEG) to record the patient’s intracranial brain activity in many small regions. iEEG data are high-dimensional…

急诊普外科结局工具变量研究中的偏倚鼓励与异质性效应AI 解读

We investigate the efficacy of surgical versus nonsurgical management for two gastrointestinal conditions, colitis and diverticulitis, using observational data. We deploy an instrumental variable design with surgeons’ tendencies to operate as an instrument. Assuming instrument validity, we find that nonsurgical alternatives can reduce both hospital length of stay and the risk of complications, with estimated effects larger for septic patients than for nonseptic patients. The…

利用半正交非负矩阵分解对分诊记录进行主题建模AI 解读

Emergency department (ED) crowding is a universal health issue that affects the efficiency of hospital management and patient care quality. ED crowding frequently occurs when a request for a ward-bed for a patient is delayed until a doctor makes an admission decision. In this case study, we build a classifier to predict the disposition of patients using manually typed nurse notes collected during triage as provided by the Alberta Medical Center. These predictions can…

IFAA：微生物组绝对丰度的稳健关联识别与推断AI 解读

The target of inference in microbiome analyses is usually relative abundance (RA) because RA in a sample (e.g., stool) can be considered as an approximation of RA in an entire ecosystem (e.g., gut). However, inference on RA suffers from the fact that RA are calculated by dividing absolute abundances (AAs) over the common denominator (CD), the summation of all AA (i.e., library size). Because of that, perturbation in one taxon will result in a change in the CD and thus cause…

通过图距离建模网络总体AI 解读

This article introduces a new class of models for multiple networks. The core idea is to parameterize a distribution on labeled graphs in terms of a Fréchet mean graph (which depends on a user-specified choice of metric or graph distance) and a parameter that controls the concentration of this distribution about its mean. Entropy is the natural parameter for such control, varying from a point mass concentrated on the Fréchet mean itself to a uniform distribution over all…

多阈值回归不连续设计中的处理效应外推AI 解读

In non-experimental settings, the Regression Discontinuity (RD) design is one of the most credible identification strategies for program evaluation and causal inference. However, RD treatment effect estimands are necessarily local, making statistical methods for the extrapolation of these effects a key area for development. We introduce a new method for extrapolation of RD effects that relies on the presence of multiple cutoffs, and is therefore design-based. Our approach…

条件风险价值与条件预期损失的高效回测AI 解读

–Given the importance of backtesting risk models and forecasts for financial institutions and regulators, we develop an efficient empirical likelihood backtest for either conditional value-at-risk or conditional expected shortfall when the given risk variable is modeled by an ARMA-GARCH process. Using a two-step procedure, the proposed backtests require less finite moments than existing backtests, allowing for robustness to heavier tails. Furthermore, we add a constraint on…

一种新的相关系数AI 解读

–Is it possible to define a coefficient of correlation which is (a) as simple as the classical coefficients like Pearson’s correlation or Spearman’s correlation, and yet (b) consistently estimates some simple and interpretable measure of the degree of dependence between the variables, which is 0 if and only if the variables are independent and 1 if and only if one is a measurable function of the other, and (c) has a simple asymptotic theory under the hypothesis of…