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多维函数型数据的低秩协方差函数估计AI 解读

Jiayi Wanga, Raymond K. W. Wonga* & Xiaoke Zhangb a Department of Statistics, Texas A&M University, College Station, TX; b Department of Statistics, George Washington University, Washington, DC Supplementary materials for this article are available online. Please go to www.tandfonline.com/r/JASA. CONTACT Raymond K. W. Wong raywong@tamu.edu Department of Statistics, Texas A&M University , College Station , TX 77843.AbstractMultidimensional function data arise from many fields…

基于模式导向抽样的大规模数据流监测AI 解读

Monitoring large-scale datastreams with limited resources has become increasingly important for real-time detection of abnormal activities in many applications. Despite the availability of large datasets, the challenges associated with designing an efficient change-detection when clustering or spatial pattern exists are not yet well addressed. In this article, a design-adaptive testing procedure is developed when only a limited number of streaming observations can be…

函数型数据的 Copula 高斯图模型AI 解读

We introduce a statistical graphical model for multivariate functional data, which are common in medical applications such as EEG and fMRI. Recently published functional graphical models rely on the multivariate Gaussian process assumption, but we relax it by introducing the functional copula Gaussian graphical model (FCGGM). This model removes the marginal Gaussian assumption but retains the simplicity of the Gaussian dependence structure, which is particularly attractive…

随机系数二元响应模型的非参数极大似然方法AI 解读

The venerable method of maximum likelihood has found numerous recent applications in nonparametric estimation of regression and shape constrained densities. For mixture models the nonparametric maximum likelihood estimator (NPMLE) of Kiefer and Wolfowitz plays a central role in recent developments of empirical Bayes methods. The NPMLE has also been proposed by Cosslett as an estimation method for single index linear models for binary response with random coefficients.…

刻画效应修饰的半参数方法AI 解读

One fundamental statistical question for research areas such as precision medicine and health disparity is about discovering effect modification of treatment or exposure by observed covariates. We propose a semiparametric framework for identifying such effect modification. Instead of using the traditional outcome models, we directly posit semiparametric models on contrasts, or expected differences of the outcome under different treatment choices or exposures. Through…

通过与替代分布混合进行贝叶斯因子的蒙特卡洛近似AI 解读

By mixing the target posterior distribution with a surrogate distribution, of which the normalizing constant is tractable, we propose a method for estimating the marginal likelihood using the Wang–Landau algorithm. We show that a faster convergence of the proposed method can be achieved via the momentum acceleration. Two implementation strategies are detailed: (i) facilitating global jumps between the posterior and surrogate distributions via the multiple-try Metropolis…

在大量测量不完整的大型系统发育树上推断表型性状演化AI 解读

Comparative biologists are often interested in inferring covariation between multiple biological traits sampled across numerous related taxa. To properly study these relationships, we must control for the shared evolutionary history of the taxa to avoid spurious inference. An additional challenge arises as obtaining a full suite of measurements becomes increasingly difficult with increasing taxa. This generally necessitates data imputation or integration, and existing…

相关数据的交叉验证AI 解读

–K-fold cross-validation (CV) with squared error loss is widely used for evaluating predictive models, especially when strong distributional assumptions cannot be taken. However, CV with squared error loss is not free from distributional assumptions, in particular in cases involving non-iid data. This article analyzes CV for correlated data. We present a criterion for suitability of standard CV in presence of correlations. When this criterion does not hold, we introduce a…

面向多响应数据的低秩高维多元线性模型估计AI 解读

In this article, we study low rank high-dimensional multivariate linear models (LRMLM) for high-dimensional multi-response data. We propose an intuitively appealing estimation approach and develop an algorithm for implementation purposes. Asymptotic properties are established to justify the estimation procedure theoretically. Intensive simulation studies are also conducted to demonstrate performance when the sample size is finite, and a comparison is made with some popular…

基于高斯混合模型的多变量缺失数据半参数分数插补AI 解读

Item nonresponse is frequently encountered in practice. Ignoring missing data can lose efficiency and lead to misleading inference. Fractional imputation is a frequentist approach of imputation for handling missing data. However, the parametric fractional imputation may be subject to bias under model misspecification. In this article, we propose a novel semiparametric fractional imputation (SFI) method using Gaussian mixture models. The proposed method is computationally…

基于最优匹配的分布无关多样本检验及单细胞基因组学应用AI 解读

In this article, we propose a nonparametric graphical test based on optimal matching, for assessing the equality of multiple unknown multivariate probability distributions. Our procedure pools the data from the different classes to create a graph based on the minimum non-bipartite matching, and then utilizes the number of edges connecting data points from different classes to examine the closeness between the distributions. The proposed test is exactly distribution-free (the…

Hellinger 相关系数AI 解读

In this article, the defining properties of any valid measure of the dependence between two continuous random variables are revisited and complemented with two original ones, shown to imply other usual postulates. While other popular choices are proved to violate some of these requirements, a class of dependence measures satisfying all of them is identified. One particular measure, that we call the Hellinger correlation, appears as a natural choice within that class due to…

动态治疗方案：精准医疗的统计方法AI 解读

Dynamic treatment regimes (DTRs) are used for managing chronic disease, and fit nicely into the larger paradigm of precision medicine. There is an increasing focus on methodology for dynamic treatm...

从固定设计到随机设计回归：偏差—方差分解、协方差惩罚与预测误差估计——更正AI 解读

Saharon Rosseta and Ryan J. TibshiranibaDepartment of Statistics and Operations Research, Tel Aviv University, Tel Aviv, Israel; bDepartment of Statistics and Data Science, Carnegie Mellon Universi...

带标记仅出现数据建模：马拉维女性性工作者规模估计AI 解读

Certain subpopulations like female sex workers (FSW), men who have sex with men (MSM), and people who inject drugs (PWID) often have higher prevalence of HIV/AIDS and are difficult to map directly due to stigma, discrimination, and criminalization. Fine-scale mapping of those populations contributes to the progress towards reducing the inequalities and ending the AIDS epidemic. In 2016 and 2017, the PLACE surveys were conducted at 3,290 venues in 20 out of the total 28…

额叶脑电不对称与抑郁的年龄及性别相关性：函数回归中的多重插补AI 解读

Frontal power asymmetry (FA), a measure of brain function derived from electroencephalography, is a potential biomarker for major depressive disorder (MDD). Though FA is functional in nature, it is typically reduced to a scalar value prior to analysis, possibly obscuring its relationship with MDD and leading to a number of studies that have provided contradictory results. To overcome this issue, we sought to fit a functional regression model to characterize the association…

高维张量时间序列的因子模型AI 解读

Large tensor (multi-dimensional array) data routinely appear nowadays in a wide range of applications, due to modern data collection capabilities. Often such observations are taken over time, forming tensor time series. In this article we present a factor model approach to the analysis of high-dimensional dynamic tensor time series and multi-category dynamic transport networks. This article presents two estimation procedures along with their theoretical properties and…

通过模型定向掩蔽与多重插补平衡推断完整性和披露风险AI 解读

There is a growing expectation that data collected by government-funded studies should be openly available to ensure research reproducibility, and so is the concern on data-privacy. A strategy to protect individuals' identity is to release multiply imputed (MI) synthetic datasets with masked sensitivity values (Rubin, 1993). However, information loss or incorrectly specified imputation models can weaken or invalidate the inferences obtained from the MI-datasets. Studying a…

采用可逆 SGLD 提议的小批量 Metropolis–Hastings 方法AI 解读

Traditional Markov chain Monte Carlo (MCMC) algorithms are computationally intensive and do not scale well to large data. In particular, the Metropolis–Hastings (MH) algorithm requires passing over the entire dataset to evaluate the likelihood ratio in each iteration. We propose a general framework for performing MH-MCMC using mini-batches of the whole dataset and show that this gives rise to approximately a tempered stationary distribution. We prove that the algorithm…

超高维协方差矩阵序列中的变化点估计AI 解读

This article considers the problem of estimating a change point in the covariance matrix in a sequence of high-dimensional vectors, where the dimension is substantially larger than the sample size. A two-stage approach is proposed to efficiently estimate the location of the change point. The first step consists of a reduction of the dimension to identify elements of the covariance matrices corresponding to significant changes. In a second step, we use the components after…

非理性亢奋：校正概率估计中的偏差AI 解读

We consider the common setting where one observes probability estimates for a large number of events, such as default risks for numerous bonds. Unfortunately, even with unbiased estimates, selecting events corresponding to the most extreme probabilities can result in systematically underestimating the true level of uncertainty. We develop an empirical Bayes approach “excess certainty adjusted probabilities” (ECAP), using a variant of Tweedie’s formula, which updates…

存在测量误差的间歇性食物摄入分布的半参数估计AI 解读

Dietary data collected from 24-hour dietary recalls are observed with significant measurement errors. In the nonparametric curve estimation literature, much of the effort has been devoted to designing methods that are consistent under contamination by noise, and which have been traditionally applied for analyzing those data. However, some foods such as alcohol or fruits are consumed only episodically, and may not be consumed during the day when the 24-hour recall is…

函数片段的均值与协方差估计AI 解读

We consider estimation of mean and covariance functions of functional snippets, which are short segments of functions possibly observed irregularly on an individual specific subinterval that is much shorter than the entire study interval. Estimation of the covariance function for functional snippets is challenging since information for the far off-diagonal regions of the covariance structure is completely missing. We address this difficulty by decomposing the covariance…

动态网络上部分观测疫情的似然推断AI 解读

We propose a generative model and an inference scheme for epidemic processes on dynamic, adaptive contact networks. Network evolution is formulated as a link-Markovian process, which is then coupled to an individual-level stochastic susceptible-infectious-recovered model, to describe the interplay between the dynamics of the disease spread and the contact network underlying the epidemic. A Markov chain Monte Carlo framework is developed for likelihood-based inference from…