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Identifying Effects of Multiple Treatments in the Presence of Unmeasured Confounding

存在未测量混杂时多重处理效应的识别

Identification of treatment effects in the presence of unmeasured confounding is a persistent problem in the social, biological, and medical sciences. The problem of unmeasured confounding in settings with multiple treatments is most common in statistical genetics and bioinformatics settings, where researchers have developed many successful statistical strategies without engaging deeply with the causal aspects of the problem. Recently there have been a number of attempts to…

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Causal Spillover Effects Using Instrumental Variables

利用工具变量识别因果溢出效应

I set up a potential outcomes framework to analyze spillover effects using instrumental variables. I characterize the population compliance types in a setting in which spillovers can occur on both treatment take-up and outcomes, and provide conditions for identification of the marginal distribution of compliance types. I show that intention-to-treat (ITT) parameters aggregate multiple direct and spillover effects for different compliance types, and hence do not have a clear…

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A Deep Generative Approach to Conditional Sampling

条件抽样的深度生成方法

We propose a deep generative approach to sampling from a conditional distribution based on a unified formulation of conditional distribution and generalized nonparametric regression function using the noise-outsourcing lemma. The proposed approach aims at learning a conditional generator, so that a random sample from the target conditional distribution can be obtained by transforming a sample drawn from a reference distribution. The conditional generator is estimated…

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Orthogonalized Kernel Debiased Machine Learning for Multimodal Data Analysis

用于多模态数据分析的正交化核去偏机器学习

Multimodal imaging has transformed neuroscience research. While it presents unprecedented opportunities, it also imposes serious challenges. Particularly, it is difficult to combine the merits of the interpretability attributed to a simple association model with the flexibility achieved by a highly adaptive nonlinear model. In this article, we propose an orthogonalized kernel debiased machine learning approach, which is built upon the Neyman orthogonality and a form of…

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Fairness-Oriented Learning for Optimal Individualized Treatment Rules

面向公平性的最优个体化处理规则学习

There has recently been a surge on the methodological development for optimal individualized treatment rule (ITR) estimation. The standard methods in the literature are designed to maximize the potential average performance (assuming larger outcomes are desirable). A notable drawback of the standard approach, due to heterogeneity in treatment response, is that the estimated optimal ITR may be suboptimal or even detrimental to certain disadvantaged subpopulations. Motivated…

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Spectral Density Estimation for Nonstationary Data With Nonzero Mean Function

非零均值函数下非平稳数据的谱密度估计

We introduce a new approach for nonparametric spectral density estimation based on the subsampling technique, which we apply to the important class of nonstationary time series. These are almost periodically correlated sequences. In contrary to existing methods, our technique does not require demeaning of the data. On the simulated data examples, we compare our estimator of spectral density function with the classical one. Additionally, we propose a modified estimator, which…

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Sparse Topic Modeling: Computational Efficiency, Near-Optimal Algorithms, and Statistical Inference

稀疏主题模型:计算效率、近最优算法与统计推断

Sparse topic modeling under the probabilistic latent semantic indexing (pLSI) model is studied. Novel and computationally fast algorithms for estimation and inference of both the word-topic matrix and the topic-document matrix are proposed and their theoretical properties are investigated. Both minimax upper and lower bounds are established and the results show that the proposed algorithms are rate-optimal, up to a logarithmic factor. Moreover, a refitting algorithm is…

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Generalized Good-Turing Improves Missing Mass Estimation

广义Good–Turing方法改进未观测概率质量估计

Consider a finite sample from an unknown distribution over a countable alphabet. The missing mass refers to the probability of symbols that do not appear in the sample. Estimating the missing mass is a basic problem in statistics and related fields, which dates back to the early work of Laplace, and the more recent seminal contribution of Good and Turing. In this article, we introduce a generalized Good-Turing (GT) framework for missing mass estimation. We derive an…

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Multifile Partitioning for Record Linkage and Duplicate Detection

用于记录链接与重复检测的多文件划分方法

Merging datafiles containing information on overlapping sets of entities is a challenging task in the absence of unique identifiers, and is further complicated when some entities are duplicated in the datafiles. Most approaches to this problem have focused on linking two files assumed to be free of duplicates, or on detecting which records in a single file are duplicates. However, it is common in practice to encounter scenarios that fit somewhere in between or beyond these…

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Inference and Estimation for Random Effects in High-Dimensional Linear Mixed Models

高维线性混合模型中随机效应的推断与估计

We consider three problems in high-dimensional linear mixed models. Without any assumptions on the design for the fixed effects, we construct asymptotic statistics for testing whether a collection of random effects is zero, derive an asymptotic confidence interval for a single random effect at the parametric rate n, and propose an empirical Bayes estimator for a part of the mean vector in ANOVA type models that performs asymptotically as well as the oracle Bayes estimator.…

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An Outer-Product-of-Gradient Approach to Dimension Reduction and its Application to Classification in High Dimensional Space

梯度外积降维方法及其在高维分类中的应用

Sufficient dimension reduction (SDR) has progressed steadily. However, its ability to improve general function estimation or classification has not been well received, especially for high-dimensional data. In this article, we first devise a local linear smoother for high dimensional nonparametric regression and then utilise it in the outer-product-of-gradient (OPG) approach of SDR. We call the method high-dimensional OPG (HOPG). To apply SDR to classification in…

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Community Detection in General Hypergraph Via Graph Embedding

通过图嵌入检测一般超图中的社区结构

Conventional network data have largely focused on pairwise interactions between two entities, yet multi-way interactions among multiple entities have been frequently observed in real-life hypergraph networks. In this article, we propose a novel method for detecting community structure in general hypergraph networks, uniform or non-uniform. The proposed method introduces a null vertex to augment a nonuniform hypergraph into a uniform multi-hypergraph, and then embeds the…

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Threshold Selection in Feature Screening for Error Rate Control

控制错误率的特征筛选阈值选择

Hard thresholding rule is commonly adopted in feature screening procedures to screen out unimportant predictors for ultrahigh-dimensional data. However, different thresholds are required to adapt to different contexts of screening problems and an appropriate thresholding magnitude usually varies from the model and error distribution. With an ad-hoc choice, it is unclear whether all of the important predictors are selected or not, and it is very likely that the procedures…

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Pseudo-Bayesian Classified Mixed Model Prediction

伪贝叶斯分类混合模型预测

We propose a new classified mixed model prediction (CMMP) procedure, called pseudo-Bayesian CMMP, that uses network information in matching the group index between the training data and new data, whose characteristics of interest one wishes to predict. The current CMMP procedures do not incorporate such information; as a result, the methods are not consistent in terms of matching the group index. Although, as the number of training data groups increases, the current CMMP…

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Nonparametric Functional Graphical Modeling Through Functional Additive Regression Operator

基于函数型加性回归算子的非参数函数图模型

In this article, we develop a nonparametric graphical model for multivariate random functions. Most existing graphical models are restricted by the assumptions of multivariate Gaussian or copula Gaussian distributions, which also imply linear relations among the random variables or functions on different nodes. We relax those assumptions by building our graphical model based on a new statistical object—the functional additive regression operator. By carrying out regression…

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Classification Trees for Imbalanced Data: Surface-to-Volume Regularization

不平衡数据的分类树:表面积与体积比正则化

Classification algorithms face difficulties when one or more classes have limited training data. We are particularly interested in classification trees, due to their interpretability and flexibility. When data are limited in one or more of the classes, the estimated decision boundaries are often irregularly shaped due to the limited sample size, leading to poor generalization error. We propose a novel approach that penalizes the Surface-to-Volume Ratio (SVR) of the decision…

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High-Order Joint Embedding for Multi-Level Link Prediction

面向多层次连边预测的高阶联合嵌入

Link prediction infers potential links from observed networks, and is one of the essential problems in network analyses. In contrast to traditional graph representation modeling which only predicts two-way pairwise relations, we propose a novel tensor-based joint network embedding approach on simultaneously encoding pairwise links and hyperlinks onto a latent space, which captures the dependency between pairwise and multi-way links in inferring potential unobserved…

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Online Estimation for Functional Data

函数型数据的在线估计

Functional data analysis has attracted considerable interest and is facing new challenges, one of which is the increasingly available data in a streaming manner. In this article we develop an online nonparametric method to dynamically update the estimates of mean and covariance functions for functional data. The kernel-type estimates can be decomposed into two sufficient statistics depending on the data-driven bandwidths. We propose to approximate the future optimal…

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Transport Monte Carlo: High-Accuracy Posterior Approximation via Random Transport

传输蒙特卡洛:通过随机传输高精度近似后验

In Bayesian applications, there is a huge interest in rapid and accurate estimation of the posterior distribution, particularly for high dimensional or hierarchical models. In this article, we propose to use optimization to solve for a joint distribution (random transport plan) between two random variables, θ from the posterior distribution and β from the simple multivariate uniform. Specifically, we obtain an approximate estimate of the conditional distribution Π(β|θ) as an…

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A General Framework for Inference on Algorithm-Agnostic Variable Importance

与算法无关的变量重要性推断的一般框架

In many applications, it is of interest to assess the relative contribution of features (or subsets of features) toward the goal of predicting a response - in other words, to gauge the variable importance of features. Most recent work on variable importance assessment has focused on describing the importance of features within the confines of a given prediction algorithm. However, such assessment does not necessarily characterize the prediction potential of features, and may…

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Test of Weak Separability for Spatially Stationary Functional Field

空间平稳函数场的弱可分性检验

For spatially dependent functional data, a generalized Karhunen-Loève expansion is commonly used to decompose data into an additive form of temporal components and spatially correlated coefficients. This structure provides a convenient model to investigate the space-time interactions, but may not hold for complex spatio-temporal processes. In this work, we introduce the concept of weak separability, and propose a formal test to examine its validity for non-replicated…

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Inference for High-Dimensional Exchangeable Arrays

高维可交换数组的统计推断

We consider inference for high-dimensional separately and jointly exchangeable arrays where the dimensions may be much larger than the sample sizes. For both exchangeable arrays, we first derive high-dimensional central limit theorems over the rectangles and subsequently develop novel multiplier bootstraps with theoretical guarantees. These theoretical results rely on new technical tools such as Hoeffding-type decomposition and maximal inequalities for the degenerate…

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Gaussian Approximation and Spatially Dependent Wild Bootstrap for High-Dimensional Spatial Data

高维空间数据的高斯逼近与空间相依野生自助法

In this article, we establish a high-dimensional CLT for the sample mean of p-dimensional spatial data observed over irregularly spaced sampling sites in Rd, allowing the dimension p to be much larger than the sample size n. We adopt a stochastic sampling scheme that can generate irregularly spaced sampling sites in a flexible manner and include both pure increasing domain and mixed increasing domain frameworks. To facilitate statistical inference, we develop the spatially…

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