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事件时间结局下最优个体化决策规则的变换不变学习AI 解读

In many important applications of precision medicine, the outcome of interest is time to an event (e.g., death, relapse of disease) and the primary goal is to identify the optimal individualized decision rule (IDR) to prolong survival time. Existing work in this area have been mostly focused on estimating the optimal IDR to maximize the restricted mean survival time in the population. We propose a new robust framework for estimating an optimal static or dynamic IDR with…

删失分位数回归的高效估计AI 解读

Censored quantile regression (CQR) has received growing attention in survival analysis because of its flexibility in modeling heterogeneous effect of covariates. Advances have been made in developing various inferential procedures under different assumptions and settings. Under the conditional independence assumption, many existing CQR methods can be characterized either by stochastic integral-based estimating equations (see, e.g., Peng and Huang) or by locally weighted…

高维广义线性模型下的迁移学习AI 解读

In this work, we study the transfer learning problem under high-dimensional generalized linear models (GLMs), which aim to improve the fit on target data by borrowing information from useful source data. Given which sources to transfer, we propose a transfer learning algorithm on GLM, and derive its l1/l2-estimation error bounds as well as a bound for a prediction error measure. The theoretical analysis shows that when the target and sources are sufficiently close to each…

凸性约束模型中局部参数的统计推断AI 解读

In this article, we develop automated inference methods for “local” parameters in a collection of convexity constrained models based on the natural constrained tuning-free estimators. A canonical example is given by the univariate convex regression model, in which automated inference is drawn for the function value, the function derivative at a fixed interior point, and the anti-mode of the convex regression function, based on the widely used tuning-free, piecewise linear…

多输出分位数回归的贝叶斯方法AI 解读

This paper presents a Bayesian approach to multiple-output quantile regression. The unconditional model is proven to be consistent and asymptotically correct frequentist confidence intervals can be obtained. The prior for the unconditional model can be elicited as the ex-ante knowledge of the distance of the tau-Tukey depth contour to the Tukey median, the first prior of its kind. A proposal for conditional regression is also presented. The model is applied to the Tennessee…

函数型数据序列周期图的最大值AI 解读

We study the periodogram operator of a sequence of functional data. Using recent advances in Gaussian approximation theory, we derive the asymptotic distribution of the maximum norm over all fundamental frequencies. We consider the case where the noise variables are independent and then generalize our results to functional linear processes. Our theory can be used for detecting periodic signals in functional time series when the length of the period is unknown. We demonstrate…

通过分位数平衡开展逆倾向加权的锐敏感性分析AI 解读

Inverse propensity weighting (IPW) is a popular method for estimating treatment effects from observational data. However, its correctness relies on the untestable (and frequently implausible) assumption that all confounders have been measured. This paper introduces a robust sensitivity analysis for IPW that estimates the range of treatment effects compatible with a given amount of unobserved confounding. The estimated range converges to the narrowest possible interval (under…

分而治之：大规模时间序列的分布式层级因子建模AI 解读

This paper proposes a hierarchical approximate-factor approach to analyzing high-dimensional, large-scale heterogeneous time series data using distributed computing. The new method employs a multiple-fold dimension reduction procedure using Principal Component Analysis (PCA) and shows great promises for modeling large-scale data that cannot be stored nor analyzed by a single machine. Each computer at the basic level performs a PCA to extract common factors among the time…

矩阵值数据的协方差估计AI 解读

Covariance estimation for matrix-valued data has received an increasing interest in applications. Unlike previous works that rely heavily on matrix normal distribution assumption and the requirement of fixed matrix size, we propose a class of distribution-free regularized covariance estimation methods for high-dimensional matrix data under a separability condition and a bandable covariance structure. Under these conditions, the original covariance matrix is decomposed into a…

通过数据拆分控制错误发现率AI 解读

Selecting relevant features associated with a given response variable is an important problem in many scientific fields. Quantifying quality and uncertainty of a selection result via false discovery rate (FDR) control has been of recent interest. This article introduces a data-splitting method (referred to as “DS”) to asymptotically control the FDR while maintaining a high power. For each feature, DS constructs a test statistic by estimating two independent regression…

协变量辅助的稀疏张量补全AI 解读

We aim to provably complete a sparse and highly missing tensor in the presence of covariate information along tensor modes. Our motivation comes from online advertising where users’ click-through-rates (CTR) on ads over various devices form a CTR tensor that has about 96% missing entries and has many zeros on nonmissing entries, which makes the standalone tensor completion method unsatisfactory. Beside the CTR tensor, additional ad features or user characteristics are often…

多视图数据中的自监督度量学习：下游任务视角AI 解读

Self-supervised metric learning has been a successful approach for learning a distance from an unlabeled dataset. The resulting distance is broadly useful for improving various distance-based downstream tasks, even when no information from downstream tasks is used in the metric learning stage. To gain insights into this approach, we develop a statistical framework to theoretically study how self-supervised metric learning can benefit downstream tasks in the context of…

高维均值向量与协方差矩阵的功效增强联合检验及基因集应用AI 解读

Power-enhanced tests with high-dimensional data have received growing attention in theoretical and applied statistics in recent years. Existing tests possess their respective high-power regions, and we may lack prior knowledge about the alternatives when testing for a problem of interest in practice. There is a critical need of developing powerful testing procedures against more general alternatives. This article studies the joint test of two-sample mean vectors and…

控制错误发现率的无模型条件特征筛选AI 解读

In this article, we propose a model-free conditional feature screening method with false discovery rate (FDR) control for ultra-high dimensional data. The proposed method is built upon a new measure of conditional independence. Thus, the new method does not require a specific functional form of the regression function and is robust to heavy-tailed responses and predictors. The variables to be conditional on are allowed to be multivariate. The proposed method enjoys sure…

快速黎曼优化下的广义低秩加稀疏张量估计AI 解读

We investigate a generalized framework to estimate a latent low-rank plus sparse tensor, where the low-rank tensor often captures the multi-way principal components and the sparse tensor accounts for potential model mis-specifications or heterogeneous signals that are unexplainable by the low-rank part. The framework flexibly covers both linear and generalized linear models, and can easily handle continuous or categorical variables. We propose a fast algorithm by integrating…

通过移位部分迹估计随机曲面的协方差AI 解读

The problem of covariance estimation for replicated surface-valued processes is examined from the functional data analysis perspective. Considerations of statistical and computational efficiency often compel the use of separability of the covariance, even though the assumption may fail in practice. We consider a setting where the covariance structure may fail to be separable locally—either due to noise contamination or due to the presence of a nonseparable short-range…

序贯新发现的贝叶斯建模AI 解读

We aim at modeling the appearance of distinct tags in a sequence of labeled objects. Common examples of this type of data include words in a corpus or distinct species in a sample. These sequential discoveries are often summarized via accumulation curves, which count the number of distinct entities observed in an increasingly large set of objects. We propose a novel Bayesian method for species sampling modeling by directly specifying the probability of a new discovery,…

通过分类实现 Metropolis–Hastings 后验采样AI 解读

This article develops a Bayesian computational platform at the interface between posterior sampling and optimization in models whose marginal likelihoods are difficult to evaluate. Inspired by contrastive learning and Generative Adversarial Networks (GAN), we reframe the likelihood function estimation problem as a classification problem. Pitting a Generator, who simulates fake data, against a Classifier, who tries to distinguish them from the real data, one obtains…

双层层级模型的分布无关预测集AI 解读

We consider the problem of constructing distribution-free prediction sets for data from two-layer hierarchical distributions. For iid data, prediction sets can be constructed using the method of conformal prediction. The validity of conformal prediction hinges on the exchangeability of the data, which does not hold when groups of observations come from distinct distributions, such as multiple observations on each patient in a medical database. We extend conformal methods to…

以先验预条件共轭梯度法加速大样本高维贝叶斯稀疏回归的 Gibbs 抽样AI 解读

In a modern observational study based on healthcare databases, the number of observations and of predictors typically range in the order of 10^{5}-10^{6} and of 10^{4}-10^{5}. Despite the large sample size, data rarely provide sufficient information to reliably estimate such a large number of parameters. Sparse regression techniques provide potential solutions, one notable approach being the Bayesian method based on shrinkage priors. In the "large n and large p" setting,…

两个二元中介下分解效应的尖锐非参数界限AI 解读

In randomized trials, once the total effect of the intervention has been estimated, it is often of interest to explore mechanistic effects through mediators along the causal pathway between the randomized treatment and the outcome. In the setting with two sequential mediators, there are a variety of decompositions of the total risk difference into mediation effects. We derive sharp and valid bounds for a number of mediation effects in the setting of two sequential mediators…

Fine–Gray 模型中的有效估计AI 解读

Direct regression for the cumulative incidence function (CIF) has become increasingly popular since the Fine and Gray model was suggested (Fine and Gray) due to its more direct interpretation on the probability risk scale. We here consider estimation within the Fine and Gray model using the theory of semiparametric efficient estimation. We show that the Fine and Gray estimator is semiparametrically efficient in the case without censoring. In the case of right-censored data,…

多层随机块模型中的偏差校正谱聚类AI 解读

We consider the problem of estimating common community structures in multi-layer stochastic block models, where each single layer may not have sufficient signal strength to recover the full community structure. In order to efficiently aggregate signal across different layers, we argue that the sum-of-squared adjacency matrices contain sufficient signal even when individual layers are very sparse. Our method uses a bias-removal step that is necessary when the squared noise…

极稀疏网络的一般成对比较模型AI 解读

Statistical estimation using pairwise comparison data is an effective approach to analyzing large-scale sparse networks. In this article, we propose a general framework to model the mutual interactions in a network, which enjoys ample flexibility in terms of model parameterization. Under this setup, we show that the maximum likelihood estimator for the latent score vector of the subjects is uniformly consistent under a near-minimal condition on network sparsity. This…