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Discussion of “A Tale of Two Datasets: Representativeness and Generalisability of Inference for Samples of Networks”

对《两个数据集的故事:网络样本推断的代表性与可推广性》的讨论

I congratulate the authors on their timely and insightful article. Since the advent of network analysis, there has been the question of the meaning of sample size in a network setting, which in the...

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Power and Multicollinearity in Small Networks: A Discussion of “Tale of Two Datasets: Representativeness and Generalisability of Inference for Samples of Networks” by Krivitsky, Coletti, and Hens

小型网络中的检验功效与多重共线性:关于网络样本推断的评论

The recent work by Krivitsky, Coletti & Hens [KCH] provides an important new contribution to the Exponential-Family Random Graph Models [ERGMs], a start-to-finish approach to dealing with multi-network ERGMs. Although multi-network ERGMs have been around for a while (mostly in the form of block-diagonal models and multi-level ERGMs, see Duxbury and Wertsching (2023), Wang et al. (2013), Slaughter and Koehly (2016)), not much care has been given to the estimation and…

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A Tale of Two Datasets: Representativeness and Generalisability of Inference for Samples of Networks

两个数据集的故事:网络样本推断的代表性与可推广性

The last two decades have seen considerable progress in foundational aspects of statistical network analysis, but the path from theory to application is not straightforward.Two large, heterogeneous samples of small networks of within-household contacts in Belgium were collected using two different but complementary sampling designs: one smaller but with all contacts in each household observed, the other larger and more representative but recording contacts of only one person…

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Bayesian Nonparametric Common Atoms Regression for Generating Synthetic Controls in Clinical Trials

利用贝叶斯非参数共同原子回归构建临床试验合成对照

The availability of electronic health records (EHR) has opened opportunities to supplement increasingly expensive and difficult to carry out randomized controlled trials (RCT) with evidence from readily available real world data. In this paper, we use EHR data to construct synthetic control arms for treatment-only single arm trials. We propose a novel nonparametric Bayesian common atoms mixture model that allows us to find equivalent population strata in the EHR and the…

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Discussion of “A Tale of Two Datasets: Representativeness and Generalisability of Inference for Samples of Networks” by Pavel N. Krivitsky, Pietro Coletti, and Niel Hens

关于《两个数据集的故事:网络样本推断的代表性与可推广性》的讨论

The notions of sample and population have been at the heart of statistics since R.A. Fisher and others distinguished sample quantities from population quantities. While sample-to-population inferen...

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Mixed-Response State-Space Model for Analyzing Multi-Dimensional Digital Phenotypes

分析多维数字表型的混合响应状态空间模型

Digital technologies (e.g., mobile phones) can be used to obtain objective, frequent, and real-world digital phenotypes from individuals. However, modeling these data poses substantial challenges since observational data are subject to confounding and various sources of variabilities. For example, signals on patients' underlying health status and treatment effects are mixed with variation due to the living environment and measurement noises. The digital phenotype data thus…

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Accommodating Time-Varying Heterogeneity in Risk Estimation under the Cox Model: A Transfer Learning Approach

容纳风险估计中的时变异质性:Cox 模型下的迁移学习

Transfer learning has attracted increasing attention in recent years for adaptively borrowing information across different data cohorts in various settings. Cancer registries have been widely used in clinical research because of their easy accessibility and large sample size. Our method is motivated by the question of how to utilize cancer registry data as a complement to improve the estimation precision of individual risks of death for inflammatory breast cancer (IBC)…

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Analyzing Big EHR Data—Optimal Cox Regression Subsampling Procedure with Rare Events

大型电子健康记录分析:稀有事件下的最优 Cox 回归子抽样

Massive sized survival datasets become increasingly prevalent with the development of the healthcare industry, and pose computational challenges unprecedented in traditional survival analysis use cases. In this work we analyze the UK-biobank colorectal cancer data with genetic and environmental risk factors, including a time-dependent coefficient, which transforms the dataset into “pseudo-observation” form, thus, critically inflating its size. A popular way for coping with…

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Modeling Postoperative Mortality in Older Patients by Boosting Discrete-Time Competing Risks Models

利用提升式离散时间竞争风险模型分析老年患者术后死亡

Elderly patients are at a high risk of suffering from postoperative death. Personalized strategies to improve their recovery after intervention are therefore urgently needed. A popular way to analyze postoperative mortality is to develop a prognostic model that incorporates risk factors measured at hospital admission, for example, comorbidities. When building such models, numerous issues must be addressed, including censoring and the presence of competing events (such as…

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Covariate-Informed Latent Interaction Models: Addressing Geographic & Taxonomic Bias in Predicting Bird–Plant Interactions

协变量引导的潜在交互模型:校正鸟类与植物互动预测的地理及分类偏差

Reductions in natural habitats urge that we better understand species’ interconnection and how biological communities respond to environmental changes. However, ecological studies of species’ interactions are limited by their geographic and taxonomic focus which can distort our understanding of interaction dynamics. We focus on bird–plant interactions that refer to situations of potential fruit consumption and seed dispersal. We develop an approach for predicting species’…

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What is a Randomization Test?

什么是随机化检验?

The meaning of randomization tests has become obscure in statistics education and practice over the last century.This article makes a fresh attempt at rectifying this core concept of statistics.A new term-"quasirandomization test"-is introduced to define significance tests based on theoretical models and distinguish these tests from the "randomization tests" based on the physical act of randomization.The practical importance of this distinction is illustrated through a real…

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Multiple Change Point Detection in Reduced Rank High Dimensional Vector Autoregressive Models

低秩高维向量自回归模型的多重变点检测

We study the problem of detecting and locating change points in high-dimensional Vector Autoregressive (VAR) models, whose transition matrices exhibit low rank plus sparse structure. We first address the problem of detecting a single change point using an exhaustive search algorithm and establish a finite sample error bound for its accuracy. Next, we extend the results to the case of multiple change points that can grow as a function of the sample size. Their detection is…

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Reversible Jump PDMP Samplers for Variable Selection

用于变量选择的可逆跳跃分段确定性马尔可夫过程采样器

A new class of Markov chain Monte Carlo (MCMC) algorithms, based on simulating piecewise deterministic Markov processes (PDMPs), has recently shown great promise: they are nonreversible, can mix better than standard MCMC algorithms, and can use subsampling ideas to speed up computation in big data scenarios. However, current PDMP samplers can only sample from posterior densities that are differentiable almost everywhere, which precludes their use for model choice. Motivated…

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Benign Overfitting and Noisy Features

良性过拟合与含噪特征

Modern machine learning models often exhibit the benign overfitting phenomenon, which has recently been characterized using the double descent curves. In addition to the classical U-shaped learning curve, the learning risk undergoes another descent as we increase the number of parameters beyond a certain threshold. In this article, we examine the conditions under which benign overfitting occurs in the random feature (RF) models, that is, in a two-layer neural network with…

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Hypothesis Tests for Structured Rank Correlation Matrices

结构化秩相关矩阵的假设检验

Joint modeling of a large number of variables often requires dimension reduction strategies that lead to structural assumptions of the underlying correlation matrix, such as equal pair-wise correlations within subsets of variables. The underlying correlation matrix is thus of interest for both model specification and model validation. In this article, we develop tests of the hypothesis that the entries of the Kendall rank correlation matrix are linear combinations of a…

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Online Bootstrap Inference For Policy Evaluation In Reinforcement Learning

强化学习策略评估的在线自助法推断

The recent emergence of reinforcement learning (RL) has created a demand for robust statistical inference methods for the parameter estimates computed using these algorithms. Existing methods for inference in online learning are restricted to settings involving independently sampled observations, while inference methods in RL have so far been limited to the batch setting. The bootstrap is a flexible and efficient approach for statistical inference in online learning…

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Learning Topic Models: Identifiability and Finite-Sample Analysis

主题模型学习:可识别性与有限样本分析

Topic models provide a useful text-mining tool for learning, extracting, and discovering latent structures in large text corpora. Although a plethora of methods have been proposed for topic modeling, lacking in the literature is a formal theoretical investigation of the statistical identifiability and accuracy of latent topic estimation. In this article, we propose a maximum likelihood estimator (MLE) of latent topics based on a specific integrated likelihood that is…

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Permutation Tests at Nonparametric Rates

适用于非参数收敛速度的置换检验

Classical two-sample permutation tests for equality of distributions have exact size in finite samples, but they fail to control size for testing equality of parameters that summarize each distribution. This paper proposes permutation tests for equality of parameters that are estimated at root-$n$ or slower rates. Our general framework applies to both parametric and nonparametric models, with two samples or one sample split into two subsamples. Our tests have correct size…

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Bayesian Inference Using Synthetic Likelihood: Asymptotics and Adjustments

合成似然贝叶斯推断:渐近性质与调整

Implementing Bayesian inference is often computationally challenging in complex models, especially when calculating the likelihood is difficult. Synthetic likelihood is one approach for carrying out inference when the likelihood is intractable, but it is straightforward to simulate from the model. The method constructs an approximate likelihood by taking a vector summary statistic as being multivariate normal, with the unknown mean and covariance estimated by simulation.…

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Conditional Separable Effects

条件可分离效应

Researchers are often interested in treatment effects on outcomes that are only defined conditional on posttreatment events. For example, in a study of the effect of different cancer treatments on quality of life at end of follow-up, the quality of life of individuals who die during the study is undefined. In these settings, naive contrasts of outcomes conditional on posttreatment events are not average causal effects, even in randomized experiments. Therefore, the effect in…

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Rank-Based Greedy Model Averaging for High-Dimensional Survival Data

高维生存数据的秩驱动贪心模型平均

Model averaging is an effective way to enhance prediction accuracy. However, most previous works focus on low-dimensional settings with completely observed responses. To attain an accurate prediction for the risk effect of survival data with high-dimensional predictors, we propose a novel method: rank-based greedy (RG) model averaging. Specifically, adopting the transformation model with splitting predictors as working models, we doubly use the smooth concordance index…

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Approximate Selective Inference via Maximum Likelihood

基于最大似然的近似选择后推断

Several strategies have been developed recently to ensure valid inference after model selection; some of these are easy to compute, while others fare better in terms of inferential power. In this article, we consider a selective inference framework for Gaussian data. We propose a new method for inference through approximate maximum likelihood estimation. Our goal is to: (a) achieve better inferential power with the aid of randomization, (b) bypass expensive MCMC sampling…

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Improved Small Domain Estimation via Compromise Regression Weights

通过折中回归权重改进小域估计

Shrinkage estimates of small domain parameters typically use a combination of a noisy “direct” estimate that only uses data from a specific small domain and a more stable regression estimate. When the regression model is misspecified, estimation performance for the noisier domains can suffer due to substantial shrinkage toward a poorly estimated regression surface. In this article, we introduce a new class of robust, empirically-driven regression weights that target…

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Spatio-Temporal Cross-Covariance Functions under the Lagrangian Framework with Multiple Advections

多重平流拉格朗日框架下的时空交叉协方差函数

When analyzing the spatio-temporal dependence in most environmental and earth sciences variables such as pollutant concentrations at different levels of the atmosphere, a special property is observed: the covariances and cross-covariances are stronger in certain directions. This property is attributed to the presence of natural forces, such as wind, which cause the transport and dispersion of these variables. This spatio-temporal dynamics prompted the use of the Lagrangian…

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