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To Adjust or not to Adjust? Estimating the Average Treatment Effect in Randomized Experiments with Missing Covariates

调整还是不调整?协变量缺失时随机实验平均处理效应的估计

Complete randomization allows for consistent estimation of the average treatment effect based on the difference in means of the outcomes without strong modeling assumptions on the outcome-generating process. Appropriate use of the pretreatment covariates can further improve the estimation efficiency. However, missingness in covariates is common in experiments and raises an important question: should we adjust for covariates subject to missingness, and if so, how? The…

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An Additive Graphical Model for Discrete Data

离散数据的加性图模型

We introduce a nonparametric graphical model for discrete node variables based on additive conditional independence. Additive conditional independence is a three-way statistical relation that shares similar properties with conditional independence by satisfying the semi-graphoid axioms. Based on this relation we build an additive graphical model for discrete variables that does not suffer from the restriction of a parametric model such as the Ising model. We develop an…

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Selective Inference for Hierarchical Clustering

层次聚类的选择后推断

Classical tests for a difference in means control the Type I error rate when the groups are defined a priori. However, when the groups are instead defined via clustering, then applying a classical test yields an extremely inflated Type I error rate. Notably, this problem persists even if two separate and independent datasets are used to define the groups and to test for a difference in their means. To address this problem, in this article, we propose a selective inference…

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Using SVD for Topic Modeling

利用奇异值分解进行主题建模

The probabilistic topic model imposes a low-rank structure on the expectation of the corpus matrix. Therefore, singular value decomposition (SVD) is a natural tool of dimension reduction. We propose an SVD-based method for estimating a topic model. Our method constructs an estimate of the topic matrix from only a few leading singular vectors of the data matrix, and has a great advantage in memory use and computational cost for large-scale corpora. The core ideas behind our…

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Fast and Numerically Stable Particle-Based Online Additive Smoothing: The AdaSmooth Algorithm

快速且数值稳定的粒子在线加性平滑:AdaSmooth 算法

We present a novel sequential Monte Carlo approach to online smoothing of additive functionals in a very general class of path-space models. Hitherto, the solutions proposed in the literature suffer from either long-term numerical instability due to particle-path degeneracy or, in the case that degeneracy is remedied by particle approximation of the so-called backward kernel, high computational demands. In order to balance optimally computational speed against numerical…

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Subspace Estimation with Automatic Dimension and Variable Selection in Sufficient Dimension Reduction

充分降维中兼具自动维数与变量选择的子空间估计

Sufficient dimension reduction (SDR) methods target finding lower-dimensional representations of a multivariate predictor to preserve all the information about the conditional distribution of the response given the predictor. The reduction is commonly achieved by projecting the predictor onto a low-dimensional subspace. The smallest such subspace is known as the Central Subspace (CS) and is the key parameter of interest for most SDR methods. In this article, we propose a…

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Dynamic Principal Component Analysis in High Dimensions

高维动态主成分分析

Principal component analysis is a versatile tool to reduce dimensionality which has wide applications in statistics and machine learning. It is particularly useful for modeling data in high-dimensional scenarios where the number of variables p is comparable to, or much larger than the sample size n. Despite an extensive literature on this topic, researchers have focused on modeling static principal eigenvectors, which are not suitable for stochastic processes that are…

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Optimal One-Pass Nonparametric Estimation Under Memory Constraint

内存约束下最优的单遍非参数估计

For nonparametric regression in the streaming setting, where data constantly flow in and require real-time analysis, a main challenge is that data are cleared from the computer system once processed due to limited computer memory and storage. We tackle the challenge by proposing a novel one-pass estimator based on penalized orthogonal basis expansions and developing a general framework to study the interplay between statistical efficiency and memory consumption of…

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Optimal Nonparametric Inference with Two-Scale Distributional Nearest Neighbors

基于双尺度分布近邻的最优非参数推断

The weighted nearest neighbors (WNN) estimator has been popularly used as a flexible and easy-to-implement nonparametric tool for mean regression estimation. The bagging technique is an elegant way to form WNN estimators with weights automatically generated to the nearest neighbors (Steele, 2009; Biau et al., 2010); we name the resulting estimator as the distributional nearest neighbors (DNN) for easy reference. Yet, there is a lack of distributional results for such…

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Off-Policy Confidence Interval Estimation with Confounded Markov Decision Process

存在混杂的马尔可夫决策过程中的离线策略价值置信区间估计

This article is concerned with constructing a confidence interval for a target policy’s value offline based on a pre-collected observational data in infinite horizon settings. Most of the existing works assume no unmeasured variables exist that confound the observed actions. This assumption, however, is likely to be violated in real applications such as healthcare and technological industries. In this article, we show that with some auxiliary variables that mediate the…

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Scaled Process Priors for Bayesian Nonparametric Estimation of the Unseen Genetic Variation

用于未观测遗传变异估计的贝叶斯非参数缩放过程先验

There is a growing interest in the estimation of the number of unseen features, mostly driven by biological applications. A recent work brought out a peculiar property of the popular completely random measures (CRMs) as prior models in Bayesian nonparametric (BNP) inference for the unseen-features problem: for fixed prior's parameters, they all lead to a Poisson posterior distribution for the number of unseen features, which depends on the sampling information only through…

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An Empirical Bayes Approach to Shrinkage Estimation on the Manifold of Symmetric Positive-Definite Matrices

对称正定矩阵流形上收缩估计的经验贝叶斯方法

The James–Stein estimator is an estimator of the multivariate normal mean and dominates the maximum likelihood estimator (MLE) under squared error loss. The original work inspired great interest in developing shrinkage estimators for a variety of problems. Nonetheless, research on shrinkage estimation for manifold-valued data is scarce. In this article, we propose shrinkage estimators for the parameters of the Log-Normal distribution defined on the manifold of N × N…

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Nearly Dimension-Independent Sparse Linear Bandit over Small Action Spaces via Best Subset Selection

通过最佳子集选择实现小行动空间下近乎维数无关的稀疏线性赌博机

We consider the stochastic contextual bandit problem under the high dimensional linear model. We focus on the case where the action space is finite and random, with each action associated with a randomly generated contextual covariate. This setting finds essential applications such as personalized recommendations, online advertisements, and personalized medicine. However, it is very challenging to balance the exploration and exploitation tradeoff. We modify the LinUCB…

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Statistically Efficient Advantage Learning for Offline Reinforcement Learning in Infinite Horizons

无限期离线强化学习中的统计高效优势学习

We consider reinforcement learning (RL) methods in offline domains without additional online data collection, such as mobile health applications. Most of existing policy optimization algorithms in the computer science literature are developed in online settings where data are easy to collect or simulate. Their generalizations to mobile health applications with a pre-collected offline dataset remain are less explored. The aim of this article is to develop a novel advantage…

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Hidden Markov Pólya Trees for High-Dimensional Distributions

用于高维分布的隐马尔可夫 Pólya 树

The Pólya tree (PT) process is a general-purpose Bayesian nonparametric model that has found wide application in a range of inference problems. It has a simple analytic form and the posterior computation boils down to beta-binomial conjugate updates along a partition tree over the sample space. Recent development in PT models shows that performance of these models can be substantially improved by (i) allowing the partition tree to adapt to the structure of the underlying…

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Bias-Correction and Test for Mark-Point Dependence with Replicated Marked Point Processes

重复标记点过程中的标记与点依赖:偏差校正及检验

Mark-point dependence plays a critical role in research problems that can be fitted into the general framework of marked point processes. In this work, we focus on adjusting for mark-point dependence when estimating the mean and covariance functions of the mark process, given independent replicates of the marked point process. We assume that the mark process is a Gaussian process and the point process is a log-Gaussian Cox process, where the mark-point dependence is…

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Conformal Sensitivity Analysis for Individual Treatment Effects

个体处理效应的共形敏感性分析

Estimating an individual treatment effect (ITE) is essential to personalized decision making. However, existing methods for estimating the ITE often rely on unconfoundedness, an assumption that is fundamentally untestable with observed data. To assess the robustness of individual-level causal conclusion with unconfoundedness, this paper proposes a method for sensitivity analysis of the ITE, a way to estimate a range of the ITE under unobserved confounding. The method we…

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Low-Rank Regression Models for Multiple Binary Responses and their Applications to Cancer Cell-Line Encyclopedia Data

多重二元响应的低秩回归及其癌症细胞系百科数据应用

In this paper, we study high-dimensional multivariate logistic regression models in which a common set of covariates is used to predict multiple binary outcomes simultaneously. Our work is primarily motivated from many biomedical studies with correlated multiple responses such as the cancer cell-line encyclopedia project. We assume that the underlying regression coefficient matrix is simultaneously low-rank and row-wise sparse. We propose an intuitively appealing selection…

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Bayesian Markov-Switching Tensor Regression for Time-Varying Networks

用于时变网络的贝叶斯马尔可夫切换张量回归

Modeling time series of multilayer network data is challenging due to the peculiar characteristics of real-world networks, such as sparsity and abrupt structural changes. Moreover, the impact of external factors on the network edges is highly heterogeneous due to edge- and time-specific effects. Capturing all these features results in a very high-dimensional inference problem. A novel tensor-on-tensor regression model is proposed, which integrates zero-inflated logistic…

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Heavy-Tailed Density Estimation

重尾密度估计

A novel statistical method is proposed and investigated for estimating a heavy tailed density under mild smoothness assumptions. Statistical analyses of heavy-tailed distributions are susceptible to the problem of sparse information in the tail of the distribution getting washed away by unrelated features of a hefty bulk. The proposed Bayesian method avoids this problem by incorporating smoothness and tail regularization through a carefully specified semiparametric prior…

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Nonparametric Estimation of Repeated Densities with Heterogeneous Sample Sizes

样本量异质情形下多组密度的非参数估计

We consider the estimation of densities in multiple subpopulations, where the available sample size in each subpopulation greatly varies. This problem occurs in epidemiology, for example, where different diseases may share similar pathogenic mechanism but differ in their prevalence. Without specifying a parametric form, our proposed method pools information from the population and estimate the density in each subpopulation in a data-driven fashion. Drawing from functional…

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Randomization-based Joint Central Limit Theorem and Efficient Covariate Adjustment in Randomized Block 2 K Factorial Experiments

随机区组析因实验的随机化联合中心极限定理与高效协变量调整

Randomized block factorial experiments are widely used in industrial engineering, clinical trials, and social science. Researchers often use a linear model and analysis of covariance to analyze experimental results; however, limited studies have addressed the validity and robustness of the resulting inferences because assumptions for a linear model might not be justified by randomization in randomized block factorial experiments. In this article, we establish a new finite…

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A New and Unified Family of Covariate Adaptive Randomization Procedures and Their Properties

统一的协变量自适应随机化程序族及其性质

In clinical trials and other comparative studies, covariate balance is crucial for credible and efficient assessment of treatment effects. Covariate adaptive randomization (CAR) procedures are extensively used to reduce the likelihood of covariate imbalances occurring. In the literature, most studies have focused on balancing of discrete covariates. Applications of CAR with continuous covariates remain rare, especially when the interest goes beyond balancing only the first…

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Latent Network Structure Learning From High-Dimensional Multivariate Point Processes

高维多元点过程的潜在网络结构学习

Learning the latent network structure from large scale multivariate point process data is an important task in a wide range of scientific and business applications. For instance, we might wish to estimate the neuronal functional connectivity network based on spiking times recorded from a collection of neurons. To characterize the complex processes underlying the observed data, we propose a new and flexible class of nonstationary Hawkes processes that allow both excitatory…

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