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Higher-Order Least Squares: Assessing Partial Goodness of Fit of Linear Causal Models

高阶最小二乘:评估线性因果模型的局部拟合优度

We introduce a simple diagnostic test for assessing the overall or partial goodness of fit of a linear causal model with errors being independent of the covariates. In particular, we consider situations where hidden confounding is potentially present. We develop a method and discuss its capability to distinguish between covariates that are confounded with the response by latent variables and those that are not. Thus, we provide a test and methodology for partial goodness of…

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Confidently Comparing Estimates with the c-value

用 c 值有置信保证地比较估计结果

Modern statistics provides an ever-expanding toolkit for estimating unknown parameters. Consequently, applied statisticians frequently face a difficult decision: retain a parameter estimate from a familiar method or replace it with an estimate from a newer or more complex one. While it is traditional to compare estimates using risk, such comparisons are rarely conclusive in realistic settings. In response, we propose the “c-value” as a measure of confidence that a new…

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Variational Bayes for Fast and Accurate Empirical Likelihood Inference

用于快速准确经验似然推断的变分贝叶斯

We develop a fast and accurate approach to approximate posterior distributions in the Bayesian empirical likelihood framework. Bayesian empirical likelihood allows for the use of Bayesian shrinkage without specification of a full likelihood but is notorious for leading to several computational difficulties. By coupling the stochastic variational Bayes procedure with an adjusted empirical likelihood framework, the proposed method overcomes the intractability of both the exact…

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Are Latent Factor Regression and Sparse Regression Adequate?

潜在因子回归与稀疏回归是否充分?

We propose the Factor Augmented sparse linear Regression Model (FARM) that not only encompasses both the latent factor regression and sparse linear regression as special cases but also bridges dimension reduction and sparse regression together. We provide theoretical guarantees for the estimation of our model under the existence of sub-Gaussian and heavy-tailed noises (with bounded (1+x)-th moment, for all x>0), respectively. In addition, the existing works on supervised…

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Guaranteed Functional Tensor Singular Value Decomposition

具有理论保证的函数型张量奇异值分解

This paper introduces the functional tensor singular value decomposition (FTSVD), a novel dimension reduction framework for tensors with one functional mode and several tabular modes. The problem is motivated by high-order longitudinal data analysis. Our model assumes the observed data to be a random realization of an approximate CP low-rank functional tensor measured on a discrete time grid. Incorporating tensor algebra and the theory of Reproducing Kernel Hilbert Space…

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Partially Linear Additive Regression with a General Hilbertian Response

一般希尔伯特空间响应的部分线性加性回归

In this article we develop semiparametric regression techniques for fitting partially linear additive models. The methods are for a general Hilbert-space-valued response. They use a powerful technique of additive regression in profiling out the additive nonparametric components of the models, which necessarily involves additive regression of the nonadditive effects of covariates. We show that the estimators of the parametric components are n-consistent and asymptotically…

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A Random Projection Approach to Hypothesis Tests in High-Dimensional Single-Index Models

高维单指标模型假设检验的随机投影方法

In this article, we consider the problem of hypothesis testing in high-dimensional single-index models. First, we study the feasibility of applying the classical F-test to a single-index model when the dimension of covariate vector and sample size are of the same order, and derive its asymptotic null distribution and asymptotic local power function. For the ultrahigh-dimensional single-index model, we construct F-statistics based on lower-dimensional random projections of…

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Adaptive Algorithm for Multi-Armed Bandit Problem with High-Dimensional Covariates

具有高维协变量的多臂老虎机自适应算法

This article studies an important sequential decision making problem known as the multi-armed stochastic bandit problem with covariates. Under a linear bandit framework with high-dimensional covariates, we propose a general multi-stage arm allocation algorithm that integrates both arm elimination and randomized assignment strategies. By employing a class of high-dimensional regression methods for coefficient estimation, the proposed algorithm is shown to have near optimal…

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Simultaneous Decorrelation of Matrix Time Series

矩阵时间序列的同步去相关

We propose a contemporaneous bilinear transformation for a $p\times q$ matrix time series to alleviate the difficulties in modeling and forecasting matrix time series when $p$ and/or $q$ are large. The resulting transformed matrix assumes a block structure consisting of several small matrices, and those small matrix series are uncorrelated across all times. Hence an overall parsimonious model is achieved by modelling each of those small matrix series separately without the…

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Finite-dimensional Discrete Random Structures and Bayesian Clustering

有限维离散随机结构与贝叶斯聚类

Discrete random probability measures stand out as effective tools for Bayesian clustering. The investigation in the area has been very lively, with a strong emphasis on nonparametric procedures based on either the Dirichlet process or on more flexible generalizations, such as the normalized random measures with independent increments (NRMI). The literature on finite-dimensional discrete priors is much more limited and mostly confined to the standard Dirichlet-multinomial…

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Proximal Learning for Individualized Treatment Regimes Under Unmeasured Confounding

未测混杂下个体化治疗规则的近端学习

Data-driven individualized decision making has recently received increasing research interest. However, most existing methods rely on the assumption of no unmeasured confounding, which cannot be ensured in practice especially in observational studies. Motivated by the recently proposed proximal causal inference, we develop several proximal learning methods to estimate optimal individualized treatment regimes (ITRs) in the presence of unmeasured confounding. Explicitly, in…

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Valid Model-Free Spatial Prediction

有效的无模型空间预测

Predicting the response at an unobserved location is a fundamental problem in spatial statistics. Given the difficulty in modeling spatial dependence, especially in non-stationary cases, model-based prediction intervals are at risk of misspecification bias that can negatively affect their validity. Here we present a new approach for model-free nonparametric spatial prediction based on the conformal prediction machinery. Our key observation is that spatial data can be treated…

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Optimal Design of Experiments on Riemannian Manifolds

黎曼流形上的最优实验设计

The theory of optimal design of experiments has been traditionally developed on an Euclidean space. In this article, new theoretical results and an algorithm for finding the optimal design of an experiment located on a Riemannian manifold are provided. It is shown that analogously to the results in Euclidean spaces, D-optimal and G-optimal designs are equivalent on manifolds, and we provide a lower bound for the maximum prediction variance of the response evaluated over the…

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Two-Way Truncated Linear Regression Models with Extremely Thresholding Penalization

采用极端阈值惩罚的双向截断线性回归

This article introduces a new type of linear regression model with regularization. Each predictor is conditionally truncated through the presence of unknown thresholds. The new model, called the two-way truncated linear regression model (TWT-LR), is not only viewed as a nonlinear generalization of a linear model but is also a much more flexible model with greatly enhanced interpretability and applicability. The TWT-LR model performs classifications through thresholds similar…

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Operator-Induced Structural Variable Selection for Identifying Materials Genes

识别材料基因的算子诱导结构变量选择

In the emerging field of materials informatics, a fundamental task is to identify physicochemically meaningful descriptors, or materials genes, which are engineered from primary features and a set of elementary algebraic operators through compositions. Standard practice directly analyzes the high-dimensional candidate predictor space in a linear model; statistical analyses are then substantially hampered by the daunting challenge posed by the astronomically large number of…

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Handbook of Matching and Weighting Adjustments for Causal Inference

因果推断中匹配与加权调整手册

For observational studies, causal inference often relies on adjustment methods for the adjustment of confounding effects. The research of adjustment methods has a long history, and, in recent years...

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Bayesian Lesion Estimation with a Structured Spike-and-Slab Prior

采用结构化尖峰厚尾先验的贝叶斯病灶估计

Neural demyelination and brain damage accumulated in white matter appear as hyperintense areas on T2-weighted MRI scans in the form of lesions. Modeling binary images at the population level, where each voxel represents the existence of a lesion, plays an important role in understanding aging and inflammatory diseases. We propose a scalable hierarchical Bayesian spatial model, called BLESS, capable of handling binary responses by placing continuous spike-and-slab mixture…

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Fundamentals of Causal Inference: With R

因果推断基础:使用R

Fundamentals of Causal Inference: With R, by Babette Brumback provides an excellent introduction to causal inference methods and their implementations using R. The book is well-written, with many t...

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Large Scale Prediction with Decision Trees

利用决策树进行大规模预测

This article shows that decision trees constructed with Classification and Regression Trees (CART) and C4.5 methodology are consistent for regression and classification tasks, even when the number of predictor variables grows sub-exponentially with the sample size, under natural 0-norm and 1-norm sparsity constraints. The theory applies to a wide range of models, including (ordinary or logistic) additive regression models with component functions that are continuous, of…

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A Feasibility Study of Differentially Private Summary Statistics and Regression Analyses with Evaluations on Administrative and Survey Data

差分隐私汇总统计与回归分析的可行性:行政及调查数据评估

Federal administrative data, such as tax data, are invaluable for research, but because of privacy concerns, access to these data is typically limited to select agencies and a few individuals. An alternative to sharing microlevel data is to allow individuals to query statistics without directly accessing the confidential data. This article studies the feasibility of using differentially private (DP) methods to make certain queries while preserving privacy. We also include…

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A Semiparametric Inverse Reinforcement Learning Approach to Characterize Decision Making for Mental Disorders

刻画精神障碍决策行为的半参数逆强化学习方法

Major depressive disorder (MDD) is one of the leading causes of disability-adjusted life years. Emerging evidence indicates the presence of reward processing abnormalities in MDD. An important scientific question is whether the abnormalities are due to reduced sensitivity to received rewards or reduced learning ability. Motivated by the probabilistic reward task (PRT) experiment in the EMBARC study, we propose a semiparametric inverse reinforcement learning (RL) approach to…

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Heterogeneous Distributed Lag Models to Estimate Personalized Effects of Maternal Exposures to Air Pollution

估计孕期空气污染个体化效应的异质分布滞后模型

Children’s health studies support an association between maternal environmental exposures and children’s birth outcomes. A common goal is to identify critical windows of susceptibility—periods during gestation with increased association between maternal exposures and a future outcome. The timing of the critical windows and magnitude of the associations are likely heterogeneous across different levels of individual, family, and neighborhood characteristics. Using an…

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Overcoming Repeated Testing Schedule Bias in Estimates of Disease Prevalence

纠正疾病患病率估计中的重复检测安排偏差

During the COVID-19 pandemic, many institutions such as universities and workplaces implemented testing regimens with every member of some population tested longitudinally, and those testing positive isolated for some time. Although the primary purpose of such regimens was to suppress disease spread by identifying and isolating infectious individuals, testing results were often also used to obtain prevalence and incidence estimates. Such estimates are helpful in risk…

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Robust Inference and Modeling of Mean and Dispersion for Generalized Linear Models

广义线性模型中均值与离散度的稳健建模及推断

Generalized Linear Models (GLMs) are a popular class of regression models when the responses follow a distribution in the exponential family. In real data the variability often deviates from the relation imposed by the exponential family distribution, which results in over- or underdispersion. Dispersion effects may even vary in the data. Such datasets do not follow the traditional GLM distributional assumptions, leading to unreliable inference. Therefore, the family of…

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