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Copula Modeling of Serially Correlated Multivariate Data with Hidden Structures

具有隐含结构的序列相关多变量数据 Copula 建模

We propose a copula-based extension of the hidden Markov model (HMM) which applies when the observations recorded at each time in the sample are multivariate. The joint model produced by the copula extension allows decoding of the hidden states based on information from multiple observations. However, unlike the case of independent marginals, the copula dependence structure embedded into the likelihood poses additional computational challenges. We tackle the latter using a…

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Discovery and Inference of a Causal Network with Hidden Confounding

存在隐蔽混杂的因果网络发现与推断

This article proposes a novel causal discovery and inference method called GrIVET for a Gaussian directed acyclic graph with unmeasured confounders. GrIVET consists of an order-based causal discovery method and a likelihood-based inferential procedure. For causal discovery, we generalize the existing peeling algorithm to estimate the ancestral relations and candidate instruments in the presence of hidden confounders. Based on this, we propose a new procedure for instrumental…

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A Regression-Based Approach to Robust Estimation and Inference for Genetic Covariance

基于回归的遗传协方差稳健估计与推断

Genome-wide association studies (GWAS) have identified thousands of genetic variants associated with complex traits, and some variants are shown to be associated with multiple complex traits. Genetic covariance between two traits is defined as the underlying covariance of genetic effects and can be used to measure the shared genetic architecture. The data used to estimate such a genetic covariance can be from the same group or different groups of individuals, and the traits…

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Ultimate Pólya Gamma Samplers–Efficient MCMC for Possibly Imbalanced Binary and Categorical Data

面向可能不平衡二元及分类数据的高效 Pólya–Gamma 采样器

Modeling binary and categorical data is one of the most commonly encountered tasks of applied statisticians and econometricians.While Bayesian methods in this context have been available for decades now, they often require a high level of familiarity with Bayesian statistics or suffer from issues such as low sampling efficiency.To contribute to the accessibility of Bayesian models for binary and categorical data, we introduce novel latent variable representations based on…

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Bayesian Inference on High-Dimensional Multivariate Binary Responses

高维多变量二元响应的贝叶斯推断

It has become increasingly common to collect high-dimensional binary response data; for example, with the emergence of new sampling techniques in ecology. In smaller dimensions, multivariate probit (MVP) models are routinely used for inferences. However, algorithms for fitting such models face issues in scaling up to high dimensions due to the intractability of the likelihood, involving an integral over a multivariate normal distribution having no analytic form. Although a…

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Matrix Completion When Missing Is Not at Random and Its Applications in Causal Panel Data Models

非随机缺失下的矩阵补全及其在因果面板模型中的应用

This paper develops an inferential framework for matrix completion when missing is not at random and without the requirement of strong signals. Our development is based on the observation that if the number of missing entries is small enough compared to the panel size, then they can be estimated well even when missing is not at random. Taking advantage of this fact, we divide the missing entries into smaller groups and estimate each group via nuclear norm regularization. In…

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Statistical Methods in Health Disparity Research

健康差异研究中的统计方法

In Statistical Methods in Health Disparity Research, author J. Sunil Rao invokes the U.S. Department of Health and Human Services’ Healthy People 2020 definition of health disparity, which is “a pa...

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Coexchangeable Process Modeling for Uncertainty Quantification in Joint Climate Reconstruction

联合气候重建不确定性量化的联合可交换过程模型

Any experiment with climate models relies on a potentially large set of spatio-temporal boundary conditions. These can represent both the initial state of the system and/or forcings driving the model output throughout the experiment. These boundary conditions are typically fixed using available reconstructions in climate modeling studies; however, in reality they are highly uncertain, that uncertainty is unquantified, and the effect on the output of the experiment can be…

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Tree-Guided Rare Feature Selection and Logic Aggregation with Electronic Health Records Data

电子健康记录中的树引导稀有特征选择与逻辑聚合

Statistical learning with a large number of rare binary features is commonly encountered in analyzing electronic health records (EHR) data, especially in the modeling of disease onset with prior medical diagnoses and procedures. Dealing with the resulting highly sparse and large-scale binary feature matrix is notoriously challenging as conventional methods may suffer from a lack of power in testing and inconsistency in model fitting, while machine learning methods may suffer…

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Latent Multimodal Functional Graphical Model Estimation

潜在多模态函数型图模型估计

Joint multimodal functional data acquisition, where functional data from multiple modes are measured simultaneously from the same subject, has emerged as an exciting modern approach enabled by recent engineering breakthroughs in the neurological and biological sciences. One prominent motivation to acquire such data is to enable new discoveries of the underlying connectivity by combining multimodal signals. Despite the scientific interest, there remains a gap in principled…

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Frequency Detection and Change Point Estimation for Time Series of Complex Oscillation

复杂振荡时间序列的频率检测与变点估计

We consider detecting the evolutionary oscillatory pattern of a signal when it is contaminated by nonstationary noises with complexly time-varying data generating mechanism. A high-dimensional dense progressive periodogram test is proposed to accurately detect all oscillatory frequencies. A further phase-adjusted local change point detection algorithm is applied in the frequency domain to detect the locations at which the oscillatory pattern changes. Our method is shown to…

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Evaluating Dynamic Conditional Quantile Treatment Effects with Applications in Ridesharing

动态条件分位数处理效应的评估及网约车应用

Many modern tech companies, such as Google, Uber, and Didi, utilize online experiments (also known as A/B testing) to evaluate new policies against existing ones. While most studies concentrate on average treatment effects, situations with skewed and heavy-tailed outcome distributions may benefit from alternative criteria, such as quantiles. However, assessing dynamic quantile treatment effects (QTE) remains a challenge, particularly when dealing with data from ride-sourcing…

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Assessing COVID-19 Prevalence in Austria with Infection Surveys and Case Count Data as Auxiliary Information

结合感染调查与病例计数辅助信息估计奥地利新冠感染率

Countries officially record the number of COVID-19 cases based on medical tests of a subset of the population. These case count data obviously suffer from participation bias, and for prevalence estimation, these data are typically discarded in favour of infection surveys, or possibly also completed with auxiliary information. One exception is the series of infection surveys recorded by the Statistics Austria Federal Institute to study the prevalence of COVID-19 in Austria in…

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Bayesian Integrative Region Segmentation in Spatially Resolved Transcriptomic Studies

空间转录组研究中的贝叶斯整合区域分割

The spatially resolved transcriptomic study is a recently developed biological experiment that can measure gene expressions and retain spatial information simultaneously, opening a new avenue to characterize fine-grained tissue structures. In this article, we propose a nonparametric Bayesian method named BINRES to carry out the region segmentation for a tissue section by integrating all the three types of data generated during the study—gene expressions, spatial coordinates,…

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A Unified Nonparametric Fiducial Approach to Interval-Censored Data

区间删失数据的统一非参数 fiducial 推断

Censored data, where the event time is partially observed, are challenging for survival probability estimation. In this article, we introduce a novel nonparametric fiducial approach to interval-censored data, including right-censored, current status, case II censored, and mixed case censored data. The proposed approach leveraging a simple Gibbs sampler has a useful property of being “one size fits all,” that is, the proposed approach automatically adapts to all types of…

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Asymptotic Distribution-Free Independence Test for High-Dimension Data

高维数据的渐近分布无关独立性检验

Test of independence is of fundamental importance in modern data analysis, with broad applications in variable selection, graphical models, and causal inference. When the data is high dimensional and the potential dependence signal is sparse, independence testing becomes very challenging without distributional or structural assumptions. In this paper, we propose a general framework for independence testing by first fitting a classifier that distinguishes the joint and…

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Ideal Bayesian Spatial Adaptation

理想的贝叶斯局部自适应

Many real-life applications involve estimation of curves that exhibit complicated shapes including jumps or varying-frequency oscillations. Practical methods have been devised that can adapt to a locally varying complexity of an unknown function (e.g. variable-knot splines, sparse wavelet reconstructions, kernel methods or trees/forests). However, the overwhelming majority of existing asymptotic minimaxity theory is predicated on homogeneous smoothness assumptions. Focusing…

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Group Network Hawkes Process

群组网络Hawkes过程

In this work, we study the event occurrences of individuals interacting in a network. To characterize the dynamic interactions among the individuals, we propose a group network Hawkes process (GNHP) model whose network structure is observed and fixed. In particular, we introduce a latent group structure among individuals to account for the heterogeneous user-specific characteristics. A maximum likelihood approach is proposed to simultaneously cluster individuals in the…

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A Wasserstein Index of Dependence for Random Measures

随机测度依赖性的 Wasserstein 指数

Optimal transport and Wasserstein distances are flourishing in many scientific fields as a means for comparing and connecting random structures. Here we pioneer the use of an optimal transport distance between Lévy measures to solve a statistical problem. Dependent Bayesian nonparametric models provide flexible inference on distinct, yet related, groups of observations. Each component of a vector of random measures models a group of exchangeable observations, while their…

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Smoothness-Penalized Deconvolution (SPeD) of a Density Estimate

密度估计的平滑惩罚反卷积方法

This article addresses the deconvolution problem of estimating a square-integrable probability density from observations contaminated with additive measurement errors having a known density. The estimator begins with a density estimate of the contaminated observations and minimizes a reconstruction error penalized by an integrated squared mth derivative. Theory for deconvolution has mainly focused on kernel- or wavelet-based techniques, but other methods including…

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Robust Leave-One-Out Cross-Validation for High-Dimensional Bayesian Models

高维贝叶斯模型的稳健留一交叉验证

Leave-one-out cross-validation (LOO-CV) is a popular method for estimating out-of-sample predictive accuracy. However, computing LOO-CV criteria can be computationally expensive due to the need to fit the model multiple times. In the Bayesian context, importance sampling provides a possible solution but classical approaches can easily produce estimators whose asymptotic variance is infinite, making them potentially unreliable. Here we propose and analyze a novel mixture…

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Spatiotemporal Clustering with Neyman-Scott Processes via Connections to Bayesian Nonparametric Mixture Models

通过贝叶斯非参数混合模型联系实现 Neyman–Scott 时空聚类

Neyman-Scott processes (NSPs) are point process models that generate clusters of points in time or space. They are natural models for a wide range of phenomena, ranging from neural spike trains to document streams. The clustering property is achieved via a doubly stochastic formulation: first, a set of latent events is drawn from a Poisson process; then, each latent event generates a set of observed data points according to another Poisson process. This construction is…

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HAC Covariance Matrix Estimation in Quantile Regression

分位数回归中的异方差与自相关稳健协方差矩阵估计

This study considers an estimator for the asymptotic variance-covariance matrix in time-series quantile regression models which is robust to the presence of heteroscedasticity and autocorrelation. When regression errors are serially correlated, the conventional quantile regression standard errors are invalid. The proposed solution is a quantile analogue of the Newey-West robust standard errors. We establish the asymptotic properties of the heteroscedasticity and…

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